FLNC_HUMAN
Evidence for PS localization
Functions
Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 193 | Ala | Thr | Myopathy,distal,4(MPD4) | - |
| 251 | Met | Thr | Myopathy,distal,4(MPD4) | - |
| 123 | Val | Ala | Cardiomyopathy,familialhypertrophic,26(CMH26) | - |
| 1539 | Ala | Thr | Cardiomyopathy,familialhypertrophic,26(CMH26) | - |
| 1624 | Ser | Leu | Cardiomyopathy,familialrestrictive5(RCM5) | - |
| 2133 | Arg | His | Cardiomyopathy,familialhypertrophic,26(CMH26) | - |
| 2160 | Ile | Phe | Cardiomyopathy,familialrestrictive5(RCM5) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FLNC_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 31.3253 | 4 | no |
| GO:0043168 | anion binding | 31.3253 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.1205 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.1205 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.7108 | 4 | no |
| GO:0003723 | RNA binding | 24.0964 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 24.0964 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 24.0964 | 5 | no |
| GO:0043169 | cation binding | 24.0964 | 4 | no |
| GO:0046872 | metal ion binding | 24.0964 | 5 | no |
| GO:0005524 | ATP binding | 21.6867 | 5 | no |
| GO:0019900 | kinase binding | 21.6867 | 4 | no |
| GO:0019901 | protein kinase binding | 21.6867 | 5 | no |
| GO:0003779 | actin binding | 12.0482 | 4 | yes |
| GO:0030506 | ankyrin binding | 2.4096 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FLNC_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 56.6265 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 49.3976 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.1928 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 46.9880 | 4 | no |
| GO:0006996 | organelle organization | 44.5783 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 44.5783 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.3735 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 43.3735 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 40.9639 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 39.7590 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 39.7590 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 39.7590 | 5 | no |
| GO:0009966 | regulation of signal transduction | 37.3494 | 4 | no |
| GO:0010468 | regulation of gene expression | 37.3494 | 6 | no |
| GO:0022607 | cellular component assembly | 37.3494 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.1446 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 33.7349 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 33.7349 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 33.7349 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.7349 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.5301 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.3253 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.3253 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.1205 | 5 | no |
| GO:0008104 | protein localization | 28.9157 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.9157 | 4 | no |
| GO:0023056 | positive regulation of signaling | 28.9157 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 28.9157 | 5 | no |
| GO:0060341 | regulation of cellular localization | 27.7108 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 27.7108 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 27.7108 | 6 | no |
| GO:0031399 | regulation of protein modification process | 26.5060 | 6 | no |
| GO:0032880 | regulation of protein localization | 26.5060 | 5 | no |
| GO:0051049 | regulation of transport | 26.5060 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 26.5060 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.5060 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.5060 | 6 | no |
| GO:0071310 | cellular response to organic substance | 26.5060 | 4 | no |
| GO:0007010 | cytoskeleton organization | 25.3012 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 25.3012 | 5 | no |
| GO:0033043 | regulation of organelle organization | 25.3012 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.3012 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 25.3012 | 4 | no |
| GO:0009894 | regulation of catabolic process | 24.0964 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.0964 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.0964 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.0964 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 24.0964 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.8916 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.8916 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 22.8916 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 22.8916 | 6 | no |
| GO:1903829 | positive regulation of protein localization | 21.6867 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.6867 | 4 | no |
| GO:0080134 | regulation of response to stress | 20.4819 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 20.4819 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.4819 | 4 | no |
| GO:0043412 | macromolecule modification | 20.4819 | 4 | no |
| GO:0043933 | protein-containing complex organization | 20.4819 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 20.4819 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 20.4819 | 6 | no |
| GO:0031032 | actomyosin structure organization | 4.8193 | 4 | yes |
| GO:0045214 | sarcomere organization | 3.6145 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SHIP2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP25_HUMAN | [view interactions] | Low throughput | no | yes |
| NRAP_HUMAN | [view interactions] | Low throughput | no | no |
| SYNP2_HUMAN | [view interactions] | Low throughput | no | yes |
| MP2K4_HUMAN | [view interactions] | Low throughput | no | yes |
| MYOZ2_HUMAN | [view interactions] | Low throughput | no | no |
| MYOZ3_HUMAN | [view interactions] | Low throughput | no | no |
| PHLB2_HUMAN | [view interactions] | Low throughput | no | yes |
| RN123_HUMAN | [view interactions] | Low throughput | no | yes |
| SIAH2_HUMAN | [view interactions] | Low throughput | no | no |
| FBLI1_HUMAN | [view interactions] | Low throughput | no | yes |
| XIRP2_HUMAN | [view interactions] | Low throughput | no | no |
| CAN3_HUMAN | [view interactions] | Low throughput | no | no |
| GP1BA_HUMAN | [view interactions] | Low throughput | no | no |
| PCBP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SGCG_HUMAN | [view interactions] | Low throughput | no | no |
| SGCD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MYOZ1_HUMAN | [view interactions] | Low throughput | no | no |
| ADA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADA1D_HUMAN | [view interactions] | Low throughput | no | no |
| ADA1B_HUMAN | [view interactions] | Low throughput | no | no |
| MYOTI_HUMAN | [view interactions] | Low throughput | no | no |
| XIRP1_HUMAN | [view interactions] | Low throughput | no | no |
| SYNEM_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TRI54_HUMAN | [view interactions] | Low throughput | no | no |
| FXL22_HUMAN | [view interactions] | Low throughput | no | no |
| OTUD1_HUMAN | [view interactions] | Low throughput | no | yes |
| ANK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FLNC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DYSF_HUMAN | [view interactions] | Low throughput | no | no |
| KCND2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| BACD2_HUMAN | [view interactions] | High throughput | no | no |
| SNX24_HUMAN | [view interactions] | High throughput | no | yes |
| ERI2_HUMAN | [view interactions] | High throughput | no | yes |
| BACD1_HUMAN | [view interactions] | High throughput | no | no |
| CARD8_HUMAN | [view interactions] | High throughput | no | yes |
| DVL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI51A_HUMAN | [view interactions] | High throughput | no | yes |
| NAT8L_HUMAN | [view interactions] | High throughput | no | no |
| ELF5_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| ATOH1_HUMAN | [view interactions] | High throughput | no | no |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB7_HUMAN | [view interactions] | High throughput | no | yes |
| RAB8B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUAK2_HUMAN | [view interactions] | High throughput | no | yes |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NT5C_HUMAN | [view interactions] | High throughput | no | yes |
| PKHO1_HUMAN | [view interactions] | High throughput | no | no |
| FRYL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAX4_HUMAN | [view interactions] | High throughput | no | no |
| CF141_HUMAN | [view interactions] | High throughput | no | no |
| MFN1_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| SMOX_HUMAN | [view interactions] | High throughput | no | yes |
| RPGF5_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| RNF31_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| MGDP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| SSH1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RTF2_HUMAN | [view interactions] | High throughput | no | yes |
| NUDT5_HUMAN | [view interactions] | High throughput | no | no |
| SPRY7_HUMAN | [view interactions] | High throughput | no | yes |
| PKHG2_HUMAN | [view interactions] | High throughput | no | no |
| LRC61_HUMAN | [view interactions] | High throughput | no | yes |
| TANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAD1_HUMAN | [view interactions] | High throughput | no | no |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTX3_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX43_HUMAN | [view interactions] | High throughput | no | no |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHAX_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| PIAS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| RN207_HUMAN | [view interactions] | High throughput | no | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB2_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU133_HUMAN | [view interactions] | High throughput | no | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S30BP_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF9_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR28_HUMAN | [view interactions] | High throughput | no | no |
| AP3S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BIG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CT2NL_HUMAN | [view interactions] | High throughput | no | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| KCMF1_HUMAN | [view interactions] | High throughput | no | yes |
| CND1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| NUP88_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| PLRG1_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| SYEP_HUMAN | [view interactions] | High throughput | no | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| SPEE_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| METK2_HUMAN | [view interactions] | High throughput | no | no |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| SYQ_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYMC_HUMAN | [view interactions] | High throughput | no | yes |
| HMCS1_HUMAN | [view interactions] | High throughput | no | yes |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| SF3B2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| SYK_HUMAN | [view interactions] | High throughput | no | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| STK39_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| H2B2F_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| SMUF2_HUMAN | [view interactions] | High throughput | no | yes |
| MLH1_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP53_HUMAN | [view interactions] | High throughput | no | yes |
| P63_HUMAN | [view interactions] | High throughput | no | no |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| WIPI2_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASF5_HUMAN | [view interactions] | High throughput | no | yes |
| KKCC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP1_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK6_HUMAN | [view interactions] | High throughput | no | yes |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| FILA_HUMAN | [view interactions] | High throughput | no | no |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| M3K13_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFIP8_HUMAN | [view interactions] | High throughput | no | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| DDR1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNH2_HUMAN | [view interactions] | High throughput | no | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| UBC9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXF1_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPC2_HUMAN | [view interactions] | High throughput | no | no |
| REPS1_HUMAN | [view interactions] | High throughput | no | yes |