DVL1_HUMAN
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in DVL1_HUMAN |
---|---|---|---|---|
GO:0019900 | kinase binding | 33.3333 | 4 | yes |
GO:0019901 | protein kinase binding | 31.7460 | 5 | yes |
GO:0017076 | purine nucleotide binding | 31.7460 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 30.1587 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 30.1587 | 4 | no |
GO:0046872 | metal ion binding | 25.3968 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 23.8095 | 5 | no |
GO:0016301 | kinase activity | 22.2222 | 4 | no |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 22.2222 | 4 | no |
GO:0005524 | ATP binding | 22.2222 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 22.2222 | 5 | no |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 20.6349 | 4 | no |
GO:0031267 | small GTPase binding | 17.4603 | 5 | yes |
GO:0051020 | GTPase binding | 17.4603 | 4 | yes |
GO:0001664 | G protein-coupled receptor binding | 15.8730 | 4 | yes |
GO:0005109 | frizzled binding | 9.5238 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in DVL1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 76.1905 | 4 | yes |
GO:0010646 | regulation of cell communication | 71.4286 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 71.4286 | 4 | yes |
GO:0009966 | regulation of signal transduction | 69.8413 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 68.2540 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 68.2540 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 65.0794 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 65.0794 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 63.4921 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 61.9048 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 60.3175 | 5 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 58.7302 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 57.1429 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 53.9683 | 6 | yes |
GO:0010647 | positive regulation of cell communication | 49.2063 | 5 | yes |
GO:0023056 | positive regulation of signaling | 49.2063 | 4 | yes |
GO:0048584 | positive regulation of response to stimulus | 49.2063 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 47.6190 | 5 | yes |
GO:0010468 | regulation of gene expression | 47.6190 | 5 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 47.6190 | 5 | yes |
GO:0031399 | regulation of protein modification process | 46.0317 | 6 | yes |
GO:0036211 | protein modification process | 44.4444 | 4 | no |
GO:0043412 | macromolecule modification | 44.4444 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 44.4444 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 42.8571 | 6 | yes |
GO:0048585 | negative regulation of response to stimulus | 42.8571 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 42.8571 | 5 | yes |
GO:0033043 | regulation of organelle organization | 39.6825 | 5 | no |
GO:0006996 | organelle organization | 39.6825 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 39.6825 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 39.6825 | 4 | yes |
GO:0016055 | Wnt signaling pathway | 39.6825 | 5 | yes |
GO:0022607 | cellular component assembly | 39.6825 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 39.6825 | 5 | yes |
GO:0042325 | regulation of phosphorylation | 39.6825 | 7 | yes |
GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 39.6825 | 4 | yes |
GO:0010648 | negative regulation of cell communication | 39.6825 | 5 | no |
GO:0023057 | negative regulation of signaling | 39.6825 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 38.0952 | 7 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 38.0952 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 38.0952 | 5 | yes |
GO:0031401 | positive regulation of protein modification process | 38.0952 | 7 | yes |
GO:0009968 | negative regulation of signal transduction | 38.0952 | 5 | no |
GO:0010941 | regulation of cell death | 36.5079 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 36.5079 | 5 | yes |
GO:0045595 | regulation of cell differentiation | 36.5079 | 4 | no |
GO:0042981 | regulation of apoptotic process | 34.9206 | 6 | no |
GO:0043067 | regulation of programmed cell death | 34.9206 | 5 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 34.9206 | 6 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 34.9206 | 4 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 34.9206 | 7 | yes |
GO:0051252 | regulation of RNA metabolic process | 34.9206 | 5 | yes |
GO:0006355 | regulation of DNA-templated transcription | 33.3333 | 6 | yes |
GO:0008104 | protein localization | 33.3333 | 4 | yes |
GO:0031344 | regulation of cell projection organization | 33.3333 | 5 | yes |
GO:0042327 | positive regulation of phosphorylation | 33.3333 | 8 | yes |
GO:0051130 | positive regulation of cellular component organization | 33.3333 | 5 | yes |
GO:0051338 | regulation of transferase activity | 33.3333 | 4 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 33.3333 | 6 | yes |
GO:1903506 | regulation of nucleic acid-templated transcription | 33.3333 | 7 | yes |
GO:2001141 | regulation of RNA biosynthetic process | 33.3333 | 6 | yes |
GO:0042127 | regulation of cell population proliferation | 33.3333 | 4 | no |
GO:0001934 | positive regulation of protein phosphorylation | 31.7460 | 8 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 31.7460 | 5 | yes |
GO:0051049 | regulation of transport | 31.7460 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 31.7460 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 31.7460 | 4 | no |
GO:0051493 | regulation of cytoskeleton organization | 30.1587 | 6 | no |
GO:0009894 | regulation of catabolic process | 30.1587 | 4 | yes |
GO:0030030 | cell projection organization | 30.1587 | 4 | yes |
GO:0043549 | regulation of kinase activity | 30.1587 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 30.1587 | 4 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 30.1587 | 5 | yes |
GO:0030111 | regulation of Wnt signaling pathway | 30.1587 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 30.1587 | 4 | no |
GO:0071310 | cellular response to organic substance | 28.5714 | 4 | no |
GO:0051726 | regulation of cell cycle | 28.5714 | 4 | no |
GO:0007010 | cytoskeleton organization | 26.9841 | 5 | yes |
GO:0034330 | cell junction organization | 26.9841 | 4 | yes |
GO:0045859 | regulation of protein kinase activity | 26.9841 | 6 | yes |
GO:0060341 | regulation of cellular localization | 26.9841 | 4 | yes |
GO:2000145 | regulation of cell motility | 25.3968 | 4 | no |
GO:0060548 | negative regulation of cell death | 25.3968 | 5 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 25.3968 | 6 | no |
GO:0009896 | positive regulation of catabolic process | 25.3968 | 5 | yes |
GO:0032880 | regulation of protein localization | 25.3968 | 5 | yes |
GO:0008284 | positive regulation of cell population proliferation | 23.8095 | 5 | no |
GO:0043066 | negative regulation of apoptotic process | 23.8095 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 23.8095 | 6 | no |
GO:0006357 | regulation of transcription by RNA polymerase II | 23.8095 | 7 | yes |
GO:0009891 | positive regulation of biosynthetic process | 23.8095 | 5 | yes |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.8095 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 23.8095 | 7 | yes |
GO:0031328 | positive regulation of cellular biosynthetic process | 23.8095 | 6 | yes |
GO:0042176 | regulation of protein catabolic process | 23.8095 | 5 | yes |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.8095 | 6 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 23.8095 | 5 | yes |
GO:0060828 | regulation of canonical Wnt signaling pathway | 23.8095 | 6 | no |
GO:0030334 | regulation of cell migration | 23.8095 | 5 | no |
GO:0045597 | positive regulation of cell differentiation | 22.2222 | 5 | no |
GO:2001233 | regulation of apoptotic signaling pathway | 22.2222 | 5 | no |
GO:1902903 | regulation of supramolecular fiber organization | 22.2222 | 5 | no |
GO:0010942 | positive regulation of cell death | 22.2222 | 5 | no |
GO:0030162 | regulation of proteolysis | 22.2222 | 6 | yes |
GO:0051248 | negative regulation of protein metabolic process | 22.2222 | 6 | yes |
GO:0010564 | regulation of cell cycle process | 22.2222 | 5 | no |
GO:0051241 | negative regulation of multicellular organismal process | 22.2222 | 4 | no |
GO:0051347 | positive regulation of transferase activity | 22.2222 | 5 | no |
GO:0043408 | regulation of MAPK cascade | 22.2222 | 6 | no |
GO:0051129 | negative regulation of cellular component organization | 22.2222 | 5 | no |
GO:0080134 | regulation of response to stress | 22.2222 | 4 | no |
GO:0006468 | protein phosphorylation | 22.2222 | 5 | no |
GO:0016310 | phosphorylation | 22.2222 | 5 | no |
GO:0051336 | regulation of hydrolase activity | 20.6349 | 4 | no |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 20.6349 | 4 | no |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 20.6349 | 5 | no |
GO:0009057 | macromolecule catabolic process | 20.6349 | 4 | no |
GO:0030335 | positive regulation of cell migration | 20.6349 | 6 | no |
GO:0040017 | positive regulation of locomotion | 20.6349 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 20.6349 | 4 | no |
GO:2000026 | regulation of multicellular organismal development | 20.6349 | 4 | no |
GO:2000147 | positive regulation of cell motility | 20.6349 | 5 | no |
GO:0043065 | positive regulation of apoptotic process | 20.6349 | 7 | no |
GO:0043068 | positive regulation of programmed cell death | 20.6349 | 6 | no |
GO:0031329 | regulation of cellular catabolic process | 20.6349 | 5 | yes |
GO:0045732 | positive regulation of protein catabolic process | 20.6349 | 6 | yes |
GO:0045893 | positive regulation of DNA-templated transcription | 20.6349 | 7 | yes |
GO:0051254 | positive regulation of RNA metabolic process | 20.6349 | 6 | yes |
GO:1902680 | positive regulation of RNA biosynthetic process | 20.6349 | 7 | yes |
GO:1903508 | positive regulation of nucleic acid-templated transcription | 20.6349 | 8 | yes |
GO:2000027 | regulation of animal organ morphogenesis | 20.6349 | 5 | yes |
GO:0033674 | positive regulation of kinase activity | 20.6349 | 6 | no |
GO:0031175 | neuron projection development | 19.0476 | 6 | yes |
GO:0031346 | positive regulation of cell projection organization | 19.0476 | 6 | yes |
GO:0031400 | negative regulation of protein modification process | 19.0476 | 7 | yes |
GO:0043393 | regulation of protein binding | 19.0476 | 4 | yes |
GO:0050808 | synapse organization | 19.0476 | 5 | yes |
GO:0097435 | supramolecular fiber organization | 19.0476 | 4 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 17.4603 | 6 | yes |
GO:0035567 | non-canonical Wnt signaling pathway | 17.4603 | 6 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 17.4603 | 7 | yes |
GO:0090175 | regulation of establishment of planar polarity | 17.4603 | 6 | yes |
GO:1903050 | regulation of proteolysis involved in protein catabolic process | 17.4603 | 7 | yes |
GO:1903829 | positive regulation of protein localization | 17.4603 | 5 | yes |
GO:0032101 | regulation of response to external stimulus | 15.8730 | 4 | yes |
GO:0045944 | positive regulation of transcription by RNA polymerase II | 15.8730 | 8 | yes |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 15.8730 | 7 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 15.8730 | 4 | yes |
GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 15.8730 | 6 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 14.2857 | 8 | yes |
GO:0002009 | morphogenesis of an epithelium | 14.2857 | 4 | yes |
GO:0022604 | regulation of cell morphogenesis | 14.2857 | 5 | yes |
GO:0031331 | positive regulation of cellular catabolic process | 14.2857 | 6 | yes |
GO:0042326 | negative regulation of phosphorylation | 14.2857 | 8 | yes |
GO:0043086 | negative regulation of catalytic activity | 14.2857 | 4 | yes |
GO:0045862 | positive regulation of proteolysis | 14.2857 | 7 | yes |
GO:0032990 | cell part morphogenesis | 12.6984 | 4 | yes |
GO:0033365 | protein localization to organelle | 12.6984 | 5 | yes |
GO:0048812 | neuron projection morphogenesis | 12.6984 | 7 | yes |
GO:0048858 | cell projection morphogenesis | 12.6984 | 5 | yes |
GO:0060070 | canonical Wnt signaling pathway | 12.6984 | 6 | yes |
GO:0061136 | regulation of proteasomal protein catabolic process | 12.6984 | 6 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 12.6984 | 6 | yes |
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 11.1111 | 7 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 11.1111 | 5 | yes |
GO:0051348 | negative regulation of transferase activity | 11.1111 | 5 | yes |
GO:0099173 | postsynapse organization | 11.1111 | 4 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 11.1111 | 4 | yes |
GO:0106027 | neuron projection organization | 11.1111 | 6 | yes |
GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 11.1111 | 8 | yes |
GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | 11.1111 | 7 | yes |
GO:0006469 | negative regulation of protein kinase activity | 9.5238 | 7 | yes |
GO:0007411 | axon guidance | 9.5238 | 8 | yes |
GO:0032091 | negative regulation of protein binding | 9.5238 | 5 | yes |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 9.5238 | 8 | yes |
GO:0033673 | negative regulation of kinase activity | 9.5238 | 6 | yes |
GO:0051100 | negative regulation of binding | 9.5238 | 4 | yes |
GO:0097485 | neuron projection guidance | 9.5238 | 7 | yes |
GO:1901800 | positive regulation of proteasomal protein catabolic process | 9.5238 | 7 | yes |
GO:0007528 | neuromuscular junction development | 7.9365 | 6 | yes |
GO:0010976 | positive regulation of neuron projection development | 7.9365 | 7 | yes |
GO:0044057 | regulation of system process | 7.9365 | 4 | yes |
GO:0046903 | secretion | 7.9365 | 4 | yes |
GO:0051046 | regulation of secretion | 7.9365 | 5 | yes |
GO:0060429 | epithelium development | 7.9365 | 4 | yes |
GO:0060997 | dendritic spine morphogenesis | 7.9365 | 6 | yes |
GO:0097061 | dendritic spine organization | 7.9365 | 5 | yes |
GO:0099054 | presynapse assembly | 7.9365 | 5 | yes |
GO:0099172 | presynapse organization | 7.9365 | 4 | yes |
GO:1903530 | regulation of secretion by cell | 7.9365 | 4 | yes |
GO:0017157 | regulation of exocytosis | 6.3492 | 5 | yes |
GO:0031122 | cytoplasmic microtubule organization | 6.3492 | 4 | yes |
GO:0032102 | negative regulation of response to external stimulus | 6.3492 | 5 | yes |
GO:0034504 | protein localization to nucleus | 6.3492 | 6 | yes |
GO:0043113 | receptor clustering | 6.3492 | 5 | yes |
GO:0044380 | protein localization to cytoskeleton | 6.3492 | 6 | yes |
GO:0046928 | regulation of neurotransmitter secretion | 6.3492 | 4 | yes |
GO:0050821 | protein stabilization | 6.3492 | 4 | yes |
GO:0051588 | regulation of neurotransmitter transport | 6.3492 | 5 | yes |
GO:0072657 | protein localization to membrane | 6.3492 | 4 | yes |
GO:0072698 | protein localization to microtubule cytoskeleton | 6.3492 | 7 | yes |
GO:1902473 | regulation of protein localization to synapse | 6.3492 | 6 | yes |
GO:1902474 | positive regulation of protein localization to synapse | 6.3492 | 6 | yes |
GO:1903305 | regulation of regulated secretory pathway | 6.3492 | 6 | yes |
GO:1990138 | neuron projection extension | 6.3492 | 4 | yes |
GO:2000300 | regulation of synaptic vesicle exocytosis | 6.3492 | 5 | yes |
GO:0006836 | neurotransmitter transport | 4.7619 | 4 | yes |
GO:0007269 | neurotransmitter secretion | 4.7619 | 4 | yes |
GO:0021915 | neural tube development | 4.7619 | 4 | yes |
GO:0023061 | signal release | 4.7619 | 4 | yes |
GO:0031644 | regulation of nervous system process | 4.7619 | 5 | yes |
GO:0035372 | protein localization to microtubule | 4.7619 | 8 | yes |
GO:0060026 | convergent extension | 4.7619 | 5 | yes |
GO:0060029 | convergent extension involved in organogenesis | 4.7619 | 6 | yes |
GO:0071340 | skeletal muscle acetylcholine-gated channel clustering | 4.7619 | 6 | yes |
GO:0090103 | cochlea morphogenesis | 4.7619 | 4 | yes |
GO:0090178 | regulation of establishment of planar polarity involved in neural tube closure | 4.7619 | 7 | yes |
GO:0090179 | planar cell polarity pathway involved in neural tube closure | 4.7619 | 8 | yes |
GO:0098815 | modulation of excitatory postsynaptic potential | 4.7619 | 4 | yes |
GO:0099643 | signal release from synapse | 4.7619 | 5 | yes |
GO:0150011 | regulation of neuron projection arborization | 4.7619 | 6 | yes |
GO:0150012 | positive regulation of neuron projection arborization | 4.7619 | 5 | yes |
GO:1905384 | regulation of protein localization to presynapse | 4.7619 | 7 | yes |
GO:1905386 | positive regulation of protein localization to presynapse | 4.7619 | 7 | yes |
GO:2000463 | positive regulation of excitatory postsynaptic potential | 4.7619 | 5 | yes |
GO:0022007 | convergent extension involved in neural plate elongation | 3.1746 | 5 | yes |
GO:0048668 | collateral sprouting | 3.1746 | 4 | yes |
GO:0048675 | axon extension | 3.1746 | 5 | yes |
GO:0048813 | dendrite morphogenesis | 3.1746 | 8 | yes |
GO:0060027 | convergent extension involved in gastrulation | 3.1746 | 4 | yes |
GO:0060134 | prepulse inhibition | 3.1746 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in DVL1_HUMAN |
---|---|---|---|---|
DOID:0050686 | organ system cancer | 3.1746 | 3 | no |
DOID:0060038 | specific developmental disorder | 3.1746 | 3 | no |
DOID:1059 | intellectual disability | 3.1746 | 4 | no |
DOID:0050700 | cardiomyopathy | 3.1746 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 3.1746 | 5 | no |
DOID:0080000 | muscular disease | 3.1746 | 3 | no |
DOID:114 | heart disease | 3.1746 | 3 | no |
DOID:423 | myopathy | 3.1746 | 5 | no |
DOID:66 | muscle tissue disease | 3.1746 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
NKD1_HUMAN | [view interactions] | Low throughput | no | no |
NKD2_HUMAN | [view interactions] | Low throughput | no | no |
VANG1_HUMAN | [view interactions] | Low throughput | no | no |
VANG2_HUMAN | [view interactions] | Low throughput | no | no |
DVL3_HUMAN | [view interactions] | Low throughput | no | yes |
AXIN1_HUMAN | [view interactions] | Low throughput | no | yes |
CXXC4_HUMAN | [view interactions] | Low throughput | no | no |
ARHGJ_HUMAN | [view interactions] | Low throughput | no | no |
DACT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TFDP1_HUMAN | [view interactions] | Low throughput | no | yes |
KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WWTR1_HUMAN | [view interactions] | Low throughput | no | yes |
SCYL2_HUMAN | [view interactions] | Low throughput | no | yes |
NXN_HUMAN | [view interactions] | Low throughput | no | no |
ANKR6_HUMAN | [view interactions] | Low throughput | no | yes |
DVL2_HUMAN | [view interactions] | Low throughput | no | yes |
DAB2_HUMAN | [view interactions] | Low throughput | no | yes |
DAAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
SIR1_HUMAN | [view interactions] | Low throughput | no | yes |
TMM88_HUMAN | [view interactions] | Low throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HECW1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ATN1_HUMAN | [view interactions] | Low throughput | no | yes |
MUSK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
BRD7_HUMAN | [view interactions] | Low throughput | no | yes |
KLH12_HUMAN | [view interactions] | Low throughput | no | no |
DAPLE_HUMAN | [view interactions] | Low throughput | no | yes |
ARRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FRAT1_HUMAN | [view interactions] | Low throughput | no | yes |
KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RYK_HUMAN | [view interactions] | Low throughput | no | no |
PRIC1_HUMAN | [view interactions] | Low throughput | no | yes |
PRIC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CYLD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC4_HUMAN | [view interactions] | Low throughput | no | yes |
ITCH_HUMAN | [view interactions] | Low throughput | no | yes |
HUWE1_HUMAN | [view interactions] | Low throughput | no | yes |
NUMA1_HUMAN | [view interactions] | Low throughput | no | yes |
ZNRF3_HUMAN | [view interactions] | Low throughput | no | no |
FZD7_HUMAN | [view interactions] | Low throughput | no | yes |
WWP1_HUMAN | [view interactions] | Low throughput | no | yes |
WNT7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GNAI3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RNF43_HUMAN | [view interactions] | Low throughput | no | yes |
PSA3_HUMAN | [view interactions] | High throughput | no | no |
SIPA1_HUMAN | [view interactions] | High throughput | no | yes |
ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DACT2_HUMAN | [view interactions] | High throughput | no | yes |
DACT3_HUMAN | [view interactions] | High throughput | no | yes |
APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RASF9_HUMAN | [view interactions] | High throughput | no | yes |
RASFA_HUMAN | [view interactions] | High throughput | no | no |
DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
SMAD1_HUMAN | [view interactions] | High throughput | no | yes |
SMAD2_HUMAN | [view interactions] | High throughput | no | yes |
SMAD7_HUMAN | [view interactions] | High throughput | no | yes |
SMAD4_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLK1_HUMAN | [view interactions] | High throughput | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BUB1_HUMAN | [view interactions] | High throughput | no | no |
FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
MLH3_HUMAN | [view interactions] | High throughput | no | no |
MSH2_HUMAN | [view interactions] | High throughput | no | yes |
RB_HUMAN | [view interactions] | High throughput | no | yes |
UBP13_HUMAN | [view interactions] | High throughput | no | yes |
SMUF2_HUMAN | [view interactions] | High throughput | no | yes |
MOONR_HUMAN | [view interactions] | High throughput | no | yes |
CE128_HUMAN | [view interactions] | High throughput | no | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
AHI1_HUMAN | [view interactions] | High throughput | no | yes |
CEP19_HUMAN | [view interactions] | High throughput | no | no |
ADIP_HUMAN | [view interactions] | High throughput | no | yes |
CP110_HUMAN | [view interactions] | High throughput | no | yes |
CETN2_HUMAN | [view interactions] | High throughput | no | yes |
DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CP135_HUMAN | [view interactions] | High throughput | no | no |
CEP44_HUMAN | [view interactions] | High throughput | no | yes |
CEP83_HUMAN | [view interactions] | High throughput | no | yes |
PLRKT_HUMAN | [view interactions] | High throughput | no | yes |
TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI69_HUMAN | [view interactions] | High throughput | no | no |
SMYD1_HUMAN | [view interactions] | High throughput | no | no |
BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WWOX_HUMAN | [view interactions] | High throughput | no | yes |
FLNC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WWP2_HUMAN | [view interactions] | High throughput | no | no |
MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZNF74_HUMAN | [view interactions] | High throughput | no | yes |
GEPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLU_HUMAN | [view interactions] | High throughput | no | yes |
PPM1A_HUMAN | [view interactions] | High throughput | no | yes |
GGCT_HUMAN | [view interactions] | High throughput | no | yes |
FBW1A_HUMAN | [view interactions] | High throughput | no | yes |
ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTH2_HUMAN | [view interactions] | High throughput | no | yes |
LTN1_HUMAN | [view interactions] | High throughput | no | no |
KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RMD3_HUMAN | [view interactions] | High throughput | no | yes |
ADAS_HUMAN | [view interactions] | High throughput | no | yes |
ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41LA_HUMAN | [view interactions] | High throughput | no | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
K2C8_HUMAN | [view interactions] | High throughput | no | no |
LATS1_HUMAN | [view interactions] | High throughput | no | yes |
MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
PAXI_HUMAN | [view interactions] | High throughput | no | yes |
SEP10_HUMAN | [view interactions] | High throughput | no | yes |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
IFM1_HUMAN | [view interactions] | High throughput | no | no |
SENP2_HUMAN | [view interactions] | Computational | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GSK3A_HUMAN | [view interactions] | Computational | no | yes |
FZD3_HUMAN | [view interactions] | Computational | no | yes |
PAK4_HUMAN | [view interactions] | Computational | no | yes |
CDN2A_HUMAN | [view interactions] | Computational | no | yes |
WNT3_HUMAN | [view interactions] | Computational | no | no |
FZD9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CSK2B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PAK5_HUMAN | [view interactions] | Computational | no | yes |
WNT5B_HUMAN | [view interactions] | Computational | no | no |
PAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FRAT2_HUMAN | [view interactions] | Computational | no | no |
KC1G1_HUMAN | [view interactions] | Computational | no | no |
WNT7B_HUMAN | [view interactions] | Computational | no | no |
FZD6_HUMAN | [view interactions] | Computational | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
2A5A_HUMAN | [view interactions] | Computational | no | yes |
FZD8_HUMAN | [view interactions] | Computational | no | yes |
CSK22_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PAK2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PAK3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2AAA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2A5G_HUMAN | [view interactions] | Computational | no | yes |
AXIN2_HUMAN | [view interactions] | Computational | no | yes |
DAAM2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LRP6_HUMAN | [view interactions] | Computational | no | yes |
2A5E_HUMAN | [view interactions] | Computational | no | yes |
PP2AA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CXXC5_HUMAN | [view interactions] | Computational | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TIAM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PRIC3_HUMAN | [view interactions] | Computational | no | yes |
FZD5_HUMAN | [view interactions] | Computational | no | yes |
NOTC2_HUMAN | [view interactions] | Computational | no | yes |
P4K2A_HUMAN | [view interactions] | Computational | no | yes |
CUL3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WNT2_HUMAN | [view interactions] | Computational | no | no |
BAMBI_HUMAN | [view interactions] | Computational | no | yes |
PTH1R_HUMAN | [view interactions] | Computational | no | no |
WNT3A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CTHR1_HUMAN | [view interactions] | Computational | no | yes |
FZD2_HUMAN | [view interactions] | Computational | no | no |
LRP5_HUMAN | [view interactions] | Computational | no | yes |
GNAQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WNT5A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ILK_HUMAN | [view interactions] | Computational | no | no |
APCL_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
WNT4_HUMAN | [view interactions] | Computational | no | no |
FZD4_HUMAN | [view interactions] | Computational | no | yes |
WNT11_HUMAN | [view interactions] | Computational | no | no |
IQGA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
KC1G2_HUMAN | [view interactions] | Computational | no | yes |
FZD10_HUMAN | [view interactions] | Computational | no | no |
FZD1_HUMAN | [view interactions] | Computational | no | yes |
JUN_HUMAN | [view interactions] | Computational | no | yes |
WNT1_HUMAN | [view interactions] | Computational | no | no |
INVS_HUMAN | [view interactions] | Computational | no | no |
2AAB_HUMAN | [view interactions] | Computational | no | yes |
PROC_HUMAN | [view interactions] | Computational | no | no |
MK08_HUMAN | [view interactions] | Computational | no | yes |
PP2AB_HUMAN | [view interactions] | Computational | no | yes |
2A5B_HUMAN | [view interactions] | Computational | no | yes |
WNT8B_HUMAN | [view interactions] | Computational | no | no |