GNAI3_HUMAN
Evidence for PS localization
Functions
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed, PubMed, PubMed). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed). Stimulates the activity of receptor-regulated K(+) channels (PubMed). The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 40 | Gly | Arg | Auriculocondylarsyndrome1(ARCND1) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GNAI3_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 41.2500 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 40.0000 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 37.5000 | 4 | yes |
| GO:0043168 | anion binding | 37.5000 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.0000 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 33.7500 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 33.7500 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 33.7500 | 6 | yes |
| GO:0003924 | GTPase activity | 27.5000 | 7 | yes |
| GO:0043169 | cation binding | 25.0000 | 4 | yes |
| GO:0046872 | metal ion binding | 23.7500 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 23.7500 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.2500 | 5 | no |
| GO:0030695 | GTPase regulator activity | 21.2500 | 4 | no |
| GO:0005525 | GTP binding | 16.2500 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 16.2500 | 6 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 16.2500 | 5 | yes |
| GO:0001664 | G protein-coupled receptor binding | 15.0000 | 4 | yes |
| GO:0019003 | GDP binding | 7.5000 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GNAI3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 48.7500 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 48.7500 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.7500 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 37.5000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 32.5000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 32.5000 | 4 | no |
| GO:0006996 | organelle organization | 32.5000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 31.2500 | 4 | yes |
| GO:0051049 | regulation of transport | 30.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.7500 | 5 | yes |
| GO:0008104 | protein localization | 28.7500 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.5000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 26.2500 | 5 | no |
| GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.7500 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 22.5000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.5000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 22.5000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 22.5000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.5000 | 4 | no |
| GO:0010468 | regulation of gene expression | 21.2500 | 6 | no |
| GO:0031399 | regulation of protein modification process | 21.2500 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 21.2500 | 5 | no |
| GO:0033043 | regulation of organelle organization | 21.2500 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.2500 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 21.2500 | 4 | no |
| GO:0060341 | regulation of cellular localization | 21.2500 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 18.7500 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 18.7500 | 4 | yes |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 15.0000 | 4 | yes |
| GO:0009896 | positive regulation of catabolic process | 13.7500 | 5 | yes |
| GO:0010506 | regulation of autophagy | 11.2500 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 11.2500 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 10.0000 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 10.0000 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 10.0000 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 10.0000 | 4 | yes |
| GO:0010508 | positive regulation of autophagy | 8.7500 | 7 | yes |
| GO:0016241 | regulation of macroautophagy | 8.7500 | 7 | yes |
| GO:0031331 | positive regulation of cellular catabolic process | 8.7500 | 6 | yes |
| GO:0043086 | negative regulation of catalytic activity | 8.7500 | 4 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 7.5000 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 7.5000 | 6 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 7.5000 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 7.5000 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 7.5000 | 7 | yes |
| GO:0009259 | ribonucleotide metabolic process | 7.5000 | 5 | yes |
| GO:0016239 | positive regulation of macroautophagy | 7.5000 | 8 | yes |
| GO:0019693 | ribose phosphate metabolic process | 7.5000 | 4 | yes |
| GO:0031279 | regulation of cyclase activity | 7.5000 | 4 | yes |
| GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 6.2500 | 5 | yes |
| GO:0045761 | regulation of adenylate cyclase activity | 6.2500 | 5 | yes |
| GO:0051339 | regulation of lyase activity | 6.2500 | 4 | yes |
| GO:0007194 | negative regulation of adenylate cyclase activity | 3.7500 | 6 | yes |
| GO:0031280 | negative regulation of cyclase activity | 3.7500 | 5 | yes |
| GO:0051350 | negative regulation of lyase activity | 3.7500 | 5 | yes |
| GO:0046039 | GTP metabolic process | 2.5000 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RGS19_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NUCB1_HUMAN | [view interactions] | Low throughput | no | yes |
| GRM4_HUMAN | [view interactions] | Low throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRPC5_HUMAN | [view interactions] | Low throughput | no | no |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASR_HUMAN | [view interactions] | Low throughput | no | no |
| RGS12_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GPSM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTR1A_HUMAN | [view interactions] | Low throughput | no | no |
| RIC8A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| S1PR1_HUMAN | [view interactions] | Low throughput | no | no |
| DAPLE_HUMAN | [view interactions] | Low throughput | no | yes |
| RASA3_HUMAN | [view interactions] | Low throughput | no | yes |
| CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS10_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS3_HUMAN | [view interactions] | Low throughput | no | no |
| RGS16_HUMAN | [view interactions] | Low throughput | no | no |
| RGS5_HUMAN | [view interactions] | Low throughput | no | no |
| RGS7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KAP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RGS18_HUMAN | [view interactions] | Low throughput | no | yes |
| GBB3_HUMAN | [view interactions] | Low throughput | no | yes |
| GPSM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRDN_HUMAN | [view interactions] | Low throughput | no | no |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| FZD7_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS2_HUMAN | [view interactions] | Low throughput | no | no |
| STK11_HUMAN | [view interactions] | Low throughput | no | yes |
| DVL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| C5AR1_HUMAN | [view interactions] | Low throughput | no | yes |
| RB11B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| GNA11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI3R4_HUMAN | [view interactions] | High throughput | no | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| CHIO_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRIC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRGP1_HUMAN | [view interactions] | High throughput | no | no |
| SRGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STRP2_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| DERL1_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUCB2_HUMAN | [view interactions] | High throughput | no | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAT2_HUMAN | [view interactions] | High throughput | no | no |
| GBG10_HUMAN | [view interactions] | High throughput | no | no |
| GBG11_HUMAN | [view interactions] | High throughput | no | no |
| GBG5_HUMAN | [view interactions] | High throughput | no | no |
| AN13B_HUMAN | [view interactions] | High throughput | no | no |
| DCNL5_HUMAN | [view interactions] | High throughput | no | yes |
| TM222_HUMAN | [view interactions] | High throughput | no | no |
| GBG4_HUMAN | [view interactions] | High throughput | no | no |
| PCP2_HUMAN | [view interactions] | High throughput | no | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK3_HUMAN | [view interactions] | High throughput | no | yes |
| PIM3_HUMAN | [view interactions] | High throughput | no | no |
| TBCK_HUMAN | [view interactions] | High throughput | no | yes |
| HASP_HUMAN | [view interactions] | High throughput | no | yes |
| KC1G1_HUMAN | [view interactions] | High throughput | no | no |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRAF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| AT12A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX30_HUMAN | [view interactions] | High throughput | no | no |
| RGS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPSM3_HUMAN | [view interactions] | High throughput | no | no |
| PHF24_HUMAN | [view interactions] | High throughput | no | yes |
| M3K3_HUMAN | [view interactions] | High throughput | no | no |
| RIPK3_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| MICA3_HUMAN | [view interactions] | High throughput | no | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
| SCC4_HUMAN | [view interactions] | High throughput | no | no |
| TRI69_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP76_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| STT3B_HUMAN | [view interactions] | High throughput | no | yes |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCF2_HUMAN | [view interactions] | High throughput | no | no |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| RPGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH2_HUMAN | [view interactions] | High throughput | no | no |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| RDH13_HUMAN | [view interactions] | High throughput | no | no |
| OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
| AAAS_HUMAN | [view interactions] | High throughput | no | yes |
| ALG6_HUMAN | [view interactions] | High throughput | no | no |
| UBP33_HUMAN | [view interactions] | High throughput | no | yes |
| NDC1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| BRAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PUR8_HUMAN | [view interactions] | High throughput | no | yes |
| API5_HUMAN | [view interactions] | High throughput | no | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF6_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| DUS6_HUMAN | [view interactions] | High throughput | no | yes |
| DUS9_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| EDEM1_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| PKHH3_HUMAN | [view interactions] | High throughput | no | no |
| RHDF2_HUMAN | [view interactions] | High throughput | no | yes |
| MA1B1_HUMAN | [view interactions] | High throughput | no | yes |
| AVR2A_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SIK2_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI31_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| PLD5_HUMAN | [view interactions] | High throughput | no | no |
| PLD4_HUMAN | [view interactions] | High throughput | no | yes |
| PLD6_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CDV3_HUMAN | [view interactions] | High throughput | no | no |
| CCNT1_HUMAN | [view interactions] | High throughput | no | yes |
| DAF_HUMAN | [view interactions] | High throughput | no | no |
| CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP2_HUMAN | [view interactions] | High throughput | no | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 6PGD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TXND5_HUMAN | [view interactions] | High throughput | no | yes |
| UBFD1_HUMAN | [view interactions] | High throughput | no | no |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |