GNAI1_HUMAN
Evidence for PS localization
Functions
Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed, PubMed). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels . The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. Required for normal cytokinesis during mitosis (PubMed). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI002319 | MOD_NMyristoyl | MOD | 1 | 7 | - |
| ELMI002319 | MOD_NMyristoyl | MOD | 1 | 7 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GNAI1_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 28.7500 | 4 | yes |
| GO:0043168 | anion binding | 28.7500 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 27.5000 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 27.5000 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.2500 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 23.7500 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.7500 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.7500 | 6 | yes |
| GO:0043169 | cation binding | 23.7500 | 4 | yes |
| GO:0046872 | metal ion binding | 21.2500 | 5 | yes |
| GO:0004930 | G protein-coupled receptor activity | 21.2500 | 4 | no |
| GO:0003924 | GTPase activity | 20.0000 | 7 | yes |
| GO:0001664 | G protein-coupled receptor binding | 16.2500 | 4 | yes |
| GO:0005525 | GTP binding | 11.2500 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 11.2500 | 6 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 11.2500 | 5 | yes |
| GO:0050780 | dopamine receptor binding | 6.2500 | 5 | yes |
| GO:0000287 | magnesium ion binding | 3.7500 | 6 | yes |
| GO:0019003 | GDP binding | 3.7500 | 5 | yes |
| GO:0031749 | D2 dopamine receptor binding | 3.7500 | 6 | yes |
| GO:0031821 | G protein-coupled serotonin receptor binding | 3.7500 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GNAI1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 53.7500 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 47.5000 | 4 | yes |
| GO:0051049 | regulation of transport | 43.7500 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 42.5000 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 41.2500 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 36.2500 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 35.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 35.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 35.0000 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.7500 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 33.7500 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.5000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.2500 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 31.2500 | 5 | no |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 28.7500 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 28.7500 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 28.7500 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 28.7500 | 5 | no |
| GO:0023057 | negative regulation of signaling | 28.7500 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 28.7500 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 27.5000 | 4 | yes |
| GO:0060341 | regulation of cellular localization | 27.5000 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 27.5000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 27.5000 | 5 | no |
| GO:0014070 | response to organic cyclic compound | 26.2500 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 26.2500 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.2500 | 5 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | yes |
| GO:0071310 | cellular response to organic substance | 25.0000 | 4 | yes |
| GO:0030030 | cell projection organization | 25.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0031399 | regulation of protein modification process | 25.0000 | 6 | no |
| GO:0010468 | regulation of gene expression | 25.0000 | 6 | no |
| GO:0006996 | organelle organization | 25.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.7500 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 23.7500 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 23.7500 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.5000 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.5000 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.5000 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.5000 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.5000 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 22.5000 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 21.2500 | 5 | no |
| GO:0080134 | regulation of response to stress | 21.2500 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.2500 | 7 | no |
| GO:0009892 | negative regulation of metabolic process | 21.2500 | 4 | no |
| GO:0008104 | protein localization | 21.2500 | 4 | no |
| GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 18.7500 | 5 | yes |
| GO:0033993 | response to lipid | 18.7500 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 18.7500 | 6 | yes |
| GO:0010564 | regulation of cell cycle process | 17.5000 | 5 | yes |
| GO:0051726 | regulation of cell cycle | 17.5000 | 4 | yes |
| GO:1903829 | positive regulation of protein localization | 16.2500 | 5 | yes |
| GO:0071396 | cellular response to lipid | 15.0000 | 5 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 13.7500 | 5 | yes |
| GO:0097305 | response to alcohol | 12.5000 | 4 | yes |
| GO:0043434 | response to peptide hormone | 10.0000 | 4 | yes |
| GO:0032886 | regulation of microtubule-based process | 8.7500 | 4 | yes |
| GO:0070507 | regulation of microtubule cytoskeleton organization | 8.7500 | 5 | yes |
| GO:1901654 | response to ketone | 8.7500 | 4 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 8.7500 | 6 | yes |
| GO:0060236 | regulation of mitotic spindle organization | 7.5000 | 7 | yes |
| GO:0090224 | regulation of spindle organization | 7.5000 | 6 | yes |
| GO:0097306 | cellular response to alcohol | 7.5000 | 5 | yes |
| GO:1901655 | cellular response to ketone | 6.2500 | 5 | yes |
| GO:1904377 | positive regulation of protein localization to cell periphery | 6.2500 | 6 | yes |
| GO:0043949 | regulation of cAMP-mediated signaling | 5.0000 | 6 | yes |
| GO:1904776 | regulation of protein localization to cell cortex | 5.0000 | 7 | yes |
| GO:1904778 | positive regulation of protein localization to cell cortex | 5.0000 | 7 | yes |
| GO:1904321 | response to forskolin | 2.5000 | 5 | yes |
| GO:1904322 | cellular response to forskolin | 2.5000 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| C3AR_HUMAN | [view interactions] | Low throughput | no | no |
| C5AR1_HUMAN | [view interactions] | Low throughput | no | yes |
| CO5_HUMAN | [view interactions] | Low throughput | no | no |
| HCAR2_HUMAN | [view interactions] | Low throughput | no | yes |
| FFAR4_HUMAN | [view interactions] | Low throughput | no | no |
| EDN1_HUMAN | [view interactions] | Low throughput | no | no |
| FFAR3_HUMAN | [view interactions] | Low throughput | no | yes |
| FFAR2_HUMAN | [view interactions] | Low throughput | no | yes |
| GRM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRM4_HUMAN | [view interactions] | Low throughput | no | no |
| MRGX1_HUMAN | [view interactions] | Low throughput | no | no |
| PENK_HUMAN | [view interactions] | Low throughput | no | yes |
| 5HT1A_HUMAN | [view interactions] | Low throughput | no | yes |
| GPR34_HUMAN | [view interactions] | Low throughput | no | yes |
| CCR8_HUMAN | [view interactions] | Low throughput | no | no |
| RARR2_HUMAN | [view interactions] | Low throughput | no | no |
| CML1_HUMAN | [view interactions] | Low throughput | no | yes |
| OX2R_HUMAN | [view interactions] | Low throughput | no | no |
| GP101_HUMAN | [view interactions] | Low throughput | no | no |
| SSR2_HUMAN | [view interactions] | Low throughput | no | yes |
| SMS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AGRF1_HUMAN | [view interactions] | Low throughput | no | no |
| AGRL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NPY2R_HUMAN | [view interactions] | Low throughput | no | no |
| NPY4R_HUMAN | [view interactions] | Low throughput | no | yes |
| PAHO_HUMAN | [view interactions] | Low throughput | no | no |
| CCR3_HUMAN | [view interactions] | Low throughput | no | yes |
| CCR2_HUMAN | [view interactions] | Low throughput | no | yes |
| CCL2_HUMAN | [view interactions] | Low throughput | no | no |
| CX3C1_HUMAN | [view interactions] | Low throughput | no | yes |
| NMU_HUMAN | [view interactions] | Low throughput | no | no |
| NMUR2_HUMAN | [view interactions] | Low throughput | no | yes |
| SSR4_HUMAN | [view interactions] | Low throughput | no | no |
| GPR17_HUMAN | [view interactions] | Low throughput | no | no |
| RGS14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PYY_HUMAN | [view interactions] | Low throughput | no | no |
| RIC8A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GPSM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NUMA1_HUMAN | [view interactions] | Low throughput | no | yes |
| MTR1L_HUMAN | [view interactions] | Low throughput | no | no |
| MT1A_HUMAN | [view interactions] | Low throughput | no | no |
| RGS12_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AGRB2_HUMAN | [view interactions] | Low throughput | no | no |
| NCF2_HUMAN | [view interactions] | Low throughput | no | no |
| GBG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBG1_HUMAN | [view interactions] | Low throughput | no | no |
| RGS4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GPSM3_HUMAN | [view interactions] | Low throughput | no | no |
| MTR1A_HUMAN | [view interactions] | Low throughput | no | no |
| MTR1B_HUMAN | [view interactions] | Low throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | Low throughput | no | no |
| ACKR3_HUMAN | [view interactions] | Low throughput | no | no |
| CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS19_HUMAN | [view interactions] | Low throughput | no | yes |
| S1PR1_HUMAN | [view interactions] | Low throughput | no | no |
| RGS20_HUMAN | [view interactions] | Low throughput | no | no |
| GP143_HUMAN | [view interactions] | Low throughput | no | yes |
| CRFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RGS5_HUMAN | [view interactions] | Low throughput | no | no |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRGR_HUMAN | [view interactions] | Low throughput | no | no |
| PTH1R_HUMAN | [view interactions] | Low throughput | no | no |
| PI2R_HUMAN | [view interactions] | Low throughput | no | no |
| GPSM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| PGFRA_HUMAN | [view interactions] | Low throughput | no | no |
| FGFR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NGB_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS18_HUMAN | [view interactions] | Low throughput | no | yes |
| EPOR_HUMAN | [view interactions] | Low throughput | no | no |
| RASD1_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS10_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS16_HUMAN | [view interactions] | Low throughput | no | no |
| SMO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DRD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| ADCY5_HUMAN | [view interactions] | Low throughput | no | no |
| RGS1_HUMAN | [view interactions] | Low throughput | no | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OPRM_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CNR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IL8_HUMAN | [view interactions] | Low throughput | no | no |
| CXCR2_HUMAN | [view interactions] | Low throughput | no | no |
| GLR_HUMAN | [view interactions] | Low throughput | no | no |
| GLUC_HUMAN | [view interactions] | Low throughput | no | no |
| FPR2_HUMAN | [view interactions] | Low throughput | no | yes |
| NTR1_HUMAN | [view interactions] | Low throughput | no | no |
| GRM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GABR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GABR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GPR88_HUMAN | [view interactions] | Low throughput | no | no |
| S1PR5_HUMAN | [view interactions] | Low throughput | no | no |
| S1PR3_HUMAN | [view interactions] | Low throughput | no | no |
| CCKN_HUMAN | [view interactions] | Low throughput | no | yes |
| CCKAR_HUMAN | [view interactions] | Low throughput | no | no |
| CCR5_HUMAN | [view interactions] | Low throughput | no | no |
| NEUT_HUMAN | [view interactions] | Low throughput | no | no |
| GHSR_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GHRL_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CCL5_HUMAN | [view interactions] | Low throughput | no | no |
| X3CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| FPR1_HUMAN | [view interactions] | Low throughput | no | no |
| LPAR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GP183_HUMAN | [view interactions] | Low throughput | no | yes |
| ACM4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MRGX2_HUMAN | [view interactions] | Low throughput | no | yes |
| CORT_HUMAN | [view interactions] | Low throughput | no | no |
| TKN1_HUMAN | [view interactions] | Low throughput | no | yes |
| NPY1R_HUMAN | [view interactions] | Low throughput | no | no |
| NPY_HUMAN | [view interactions] | Low throughput | no | yes |
| LT4R1_HUMAN | [view interactions] | Low throughput | no | yes |
| CCR1_HUMAN | [view interactions] | Low throughput | no | no |
| CCL15_HUMAN | [view interactions] | Low throughput | no | no |
| GALR1_HUMAN | [view interactions] | Low throughput | no | no |
| GALA_HUMAN | [view interactions] | Low throughput | no | no |
| OPRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COLI_HUMAN | [view interactions] | Low throughput | no | no |
| OPRD_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PDYN_HUMAN | [view interactions] | Low throughput | no | yes |
| PNOC_HUMAN | [view interactions] | Low throughput | no | yes |
| OPRX_HUMAN | [view interactions] | Low throughput | no | no |
| GPR84_HUMAN | [view interactions] | Low throughput | no | no |
| CD69_HUMAN | [view interactions] | Low throughput | no | no |
| PE2R4_HUMAN | [view interactions] | Low throughput | no | yes |
| PE2R3_HUMAN | [view interactions] | Low throughput | no | no |
| EDNRB_HUMAN | [view interactions] | Low throughput | no | no |
| CO3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NUCB1_HUMAN | [view interactions] | High throughput | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THAP7_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNAT3_HUMAN | [view interactions] | High throughput | no | no |
| GBG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTHR_HUMAN | [view interactions] | High throughput | no | yes |
| GBG5_HUMAN | [view interactions] | High throughput | no | no |
| GBG4_HUMAN | [view interactions] | High throughput | no | no |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK3_HUMAN | [view interactions] | High throughput | no | yes |
| HASP_HUMAN | [view interactions] | High throughput | no | yes |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCN2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| RGS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCP2_HUMAN | [view interactions] | High throughput | no | no |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
| TRI69_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP76_HUMAN | [view interactions] | High throughput | no | yes |
| DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX4_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PCKGC_HUMAN | [view interactions] | High throughput | no | no |
| NCF1_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| ATP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG10_HUMAN | [view interactions] | High throughput | no | no |
| GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE3B_HUMAN | [view interactions] | High throughput | no | no |
| ABCA3_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPP2_HUMAN | [view interactions] | High throughput | no | yes |
| CNEP1_HUMAN | [view interactions] | High throughput | no | yes |
| GLI1_HUMAN | [view interactions] | High throughput | no | no |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN138_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS6_HUMAN | [view interactions] | High throughput | no | yes |
| EYA4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| GBG8_HUMAN | [view interactions] | High throughput | no | no |
| SPN1_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| OVOL2_HUMAN | [view interactions] | High throughput | no | no |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| GBB3_HUMAN | [view interactions] | High throughput | no | yes |
| GBG11_HUMAN | [view interactions] | High throughput | no | no |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI3R4_HUMAN | [view interactions] | High throughput | no | yes |
| LAT1_HUMAN | [view interactions] | High throughput | no | yes |
| GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SSR3_HUMAN | [view interactions] | High throughput | no | yes |