GNAI1_HUMAN
Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed, PubMed). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels . The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. Required for normal cytokinesis during mitosis (PubMed). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI002319 | MOD_NMyristoyl | MOD | 1 | 7 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in GNAI1_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 39.1753 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 39.1753 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 38.1443 | 4 | yes |
GO:0003924 | GTPase activity | 29.8969 | 7 | yes |
GO:0016462 | pyrophosphatase activity | 29.8969 | 5 | yes |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 29.8969 | 4 | yes |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 29.8969 | 6 | yes |
GO:0019900 | kinase binding | 23.7113 | 4 | no |
GO:0046872 | metal ion binding | 22.6804 | 4 | yes |
GO:0019901 | protein kinase binding | 21.6495 | 5 | no |
GO:0005525 | GTP binding | 20.6186 | 5 | yes |
GO:0019001 | guanyl nucleotide binding | 20.6186 | 5 | yes |
GO:0032561 | guanyl ribonucleotide binding | 20.6186 | 5 | yes |
GO:0001664 | G protein-coupled receptor binding | 17.5258 | 4 | yes |
GO:0019003 | GDP binding | 7.2165 | 4 | yes |
GO:0031821 | G protein-coupled serotonin receptor binding | 5.1546 | 5 | yes |
GO:0000287 | magnesium ion binding | 3.0928 | 5 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in GNAI1_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 62.8866 | 4 | yes |
GO:0010646 | regulation of cell communication | 61.8557 | 4 | yes |
GO:0009966 | regulation of signal transduction | 54.6392 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 53.6082 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 45.3608 | 4 | no |
GO:0010647 | positive regulation of cell communication | 44.3299 | 5 | no |
GO:0023056 | positive regulation of signaling | 44.3299 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 44.3299 | 4 | no |
GO:0051049 | regulation of transport | 43.2990 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 43.2990 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 42.2680 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 42.2680 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 40.2062 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 40.2062 | 4 | no |
GO:0051128 | regulation of cellular component organization | 39.1753 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 38.1443 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 37.1134 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 36.0825 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 35.0515 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.0515 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 35.0515 | 4 | no |
GO:0006996 | organelle organization | 34.0206 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 34.0206 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 34.0206 | 5 | no |
GO:0042325 | regulation of phosphorylation | 32.9897 | 7 | no |
GO:0031399 | regulation of protein modification process | 31.9588 | 6 | no |
GO:1902533 | positive regulation of intracellular signal transduction | 30.9278 | 6 | no |
GO:0042127 | regulation of cell population proliferation | 30.9278 | 4 | no |
GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 29.8969 | 4 | yes |
GO:0060341 | regulation of cellular localization | 29.8969 | 4 | yes |
GO:0071310 | cellular response to organic substance | 29.8969 | 4 | yes |
GO:0010468 | regulation of gene expression | 29.8969 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 29.8969 | 6 | no |
GO:0001932 | regulation of protein phosphorylation | 28.8660 | 7 | no |
GO:0010941 | regulation of cell death | 28.8660 | 4 | no |
GO:0010243 | response to organonitrogen compound | 27.8351 | 4 | yes |
GO:0032880 | regulation of protein localization | 27.8351 | 5 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 27.8351 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 27.8351 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 26.8041 | 6 | no |
GO:0042327 | positive regulation of phosphorylation | 26.8041 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 26.8041 | 7 | no |
GO:0009892 | negative regulation of metabolic process | 25.7732 | 4 | no |
GO:0043269 | regulation of ion transport | 25.7732 | 5 | no |
GO:0042981 | regulation of apoptotic process | 25.7732 | 6 | no |
GO:0043067 | regulation of programmed cell death | 25.7732 | 5 | no |
GO:0014070 | response to organic cyclic compound | 24.7423 | 4 | yes |
GO:0033043 | regulation of organelle organization | 24.7423 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.7423 | 5 | no |
GO:0031401 | positive regulation of protein modification process | 24.7423 | 7 | no |
GO:0010648 | negative regulation of cell communication | 24.7423 | 5 | no |
GO:0023057 | negative regulation of signaling | 24.7423 | 4 | no |
GO:0043408 | regulation of MAPK cascade | 24.7423 | 6 | no |
GO:0051050 | positive regulation of transport | 24.7423 | 4 | no |
GO:0051240 | positive regulation of multicellular organismal process | 24.7423 | 4 | no |
GO:0080134 | regulation of response to stress | 24.7423 | 4 | no |
GO:0051336 | regulation of hydrolase activity | 24.7423 | 4 | no |
GO:0060548 | negative regulation of cell death | 24.7423 | 5 | no |
GO:1901701 | cellular response to oxygen-containing compound | 23.7113 | 4 | yes |
GO:0022607 | cellular component assembly | 23.7113 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 23.7113 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 23.7113 | 5 | no |
GO:0051338 | regulation of transferase activity | 23.7113 | 4 | no |
GO:0030334 | regulation of cell migration | 23.7113 | 5 | no |
GO:2000145 | regulation of cell motility | 23.7113 | 4 | no |
GO:0008284 | positive regulation of cell population proliferation | 23.7113 | 5 | no |
GO:0016192 | vesicle-mediated transport | 22.6804 | 4 | no |
GO:0001934 | positive regulation of protein phosphorylation | 22.6804 | 8 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.6804 | 4 | no |
GO:0030030 | cell projection organization | 22.6804 | 4 | no |
GO:0043066 | negative regulation of apoptotic process | 22.6804 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 22.6804 | 6 | no |
GO:0051046 | regulation of secretion | 21.6495 | 5 | no |
GO:1903530 | regulation of secretion by cell | 21.6495 | 4 | no |
GO:0036211 | protein modification process | 21.6495 | 4 | no |
GO:0043412 | macromolecule modification | 21.6495 | 4 | no |
GO:0043410 | positive regulation of MAPK cascade | 21.6495 | 7 | no |
GO:0043549 | regulation of kinase activity | 21.6495 | 5 | no |
GO:0048585 | negative regulation of response to stimulus | 21.6495 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 21.6495 | 5 | no |
GO:0007010 | cytoskeleton organization | 21.6495 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 20.6186 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 20.6186 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 20.6186 | 5 | no |
GO:0051094 | positive regulation of developmental process | 20.6186 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 20.6186 | 4 | no |
GO:0033993 | response to lipid | 19.5876 | 4 | yes |
GO:0051493 | regulation of cytoskeleton organization | 19.5876 | 6 | yes |
GO:1903829 | positive regulation of protein localization | 17.5258 | 5 | yes |
GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | 16.4948 | 5 | yes |
GO:0051726 | regulation of cell cycle | 16.4948 | 4 | yes |
GO:0071396 | cellular response to lipid | 14.4330 | 5 | yes |
GO:0010564 | regulation of cell cycle process | 13.4021 | 5 | yes |
GO:0071407 | cellular response to organic cyclic compound | 13.4021 | 5 | yes |
GO:0097305 | response to alcohol | 13.4021 | 4 | yes |
GO:1901652 | response to peptide | 13.4021 | 4 | yes |
GO:1901654 | response to ketone | 12.3711 | 4 | yes |
GO:0043434 | response to peptide hormone | 11.3402 | 4 | yes |
GO:1901655 | cellular response to ketone | 9.2784 | 5 | yes |
GO:0097306 | cellular response to alcohol | 8.2474 | 5 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 8.2474 | 6 | yes |
GO:0032886 | regulation of microtubule-based process | 6.1856 | 4 | yes |
GO:0070507 | regulation of microtubule cytoskeleton organization | 6.1856 | 5 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 5.1546 | 6 | yes |
GO:1904321 | response to forskolin | 4.1237 | 5 | yes |
GO:1904322 | cellular response to forskolin | 4.1237 | 6 | yes |
GO:0043949 | regulation of cAMP-mediated signaling | 3.0928 | 6 | yes |
GO:0060236 | regulation of mitotic spindle organization | 3.0928 | 7 | yes |
GO:0090224 | regulation of spindle organization | 3.0928 | 6 | yes |
GO:1904776 | regulation of protein localization to cell cortex | 3.0928 | 7 | yes |
GO:1904778 | positive regulation of protein localization to cell cortex | 3.0928 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in GNAI1_HUMAN |
---|---|---|---|---|
DOID:0050155 | sensory system disease | 2.0619 | 3 | no |
DOID:114 | heart disease | 2.0619 | 3 | no |
DOID:0050686 | organ system cancer | 2.0619 | 3 | no |
DOID:6457 | Cowden syndrome | 2.0619 | 3 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
GABR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GLUC_HUMAN | [view interactions] | Low throughput | no | no |
CNR2_HUMAN | [view interactions] | Low throughput | no | yes |
CCR5_HUMAN | [view interactions] | Low throughput | no | no |
FPR2_HUMAN | [view interactions] | Low throughput | no | yes |
CXCR2_HUMAN | [view interactions] | Low throughput | no | no |
NTR1_HUMAN | [view interactions] | Low throughput | no | no |
NPY1R_HUMAN | [view interactions] | Low throughput | no | no |
S1PR5_HUMAN | [view interactions] | Low throughput | no | no |
RGS1_HUMAN | [view interactions] | Low throughput | no | yes |
GRM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LPAR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
OPRM_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GABR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GLR_HUMAN | [view interactions] | Low throughput | no | no |
IL8_HUMAN | [view interactions] | Low throughput | no | no |
S1PR3_HUMAN | [view interactions] | Low throughput | no | no |
RGS14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RIC8A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GPSM2_HUMAN | [view interactions] | Low throughput | no | yes |
NUMA1_HUMAN | [view interactions] | Low throughput | no | yes |
GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MTR1L_HUMAN | [view interactions] | Low throughput | no | no |
GPR88_HUMAN | [view interactions] | Low throughput | no | no |
MT1A_HUMAN | [view interactions] | Low throughput | no | no |
CCKN_HUMAN | [view interactions] | Low throughput | no | yes |
CCKAR_HUMAN | [view interactions] | Low throughput | no | no |
NEUT_HUMAN | [view interactions] | Low throughput | no | no |
GHSR_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
GHRL_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CCL5_HUMAN | [view interactions] | Low throughput | no | no |
X3CL1_HUMAN | [view interactions] | Low throughput | no | yes |
FPR1_HUMAN | [view interactions] | Low throughput | no | no |
GP183_HUMAN | [view interactions] | Low throughput | no | yes |
ACM4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MRGX2_HUMAN | [view interactions] | Low throughput | no | yes |
RGS12_HUMAN | [view interactions] | Low throughput | no | no |
CORT_HUMAN | [view interactions] | Low throughput | no | no |
GBB4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TKN1_HUMAN | [view interactions] | Low throughput | no | yes |
NPY_HUMAN | [view interactions] | Low throughput | no | yes |
GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LT4R1_HUMAN | [view interactions] | Low throughput | no | yes |
CCR1_HUMAN | [view interactions] | Low throughput | no | no |
CCL15_HUMAN | [view interactions] | Low throughput | no | no |
GALR1_HUMAN | [view interactions] | Low throughput | no | no |
GALA_HUMAN | [view interactions] | Low throughput | no | no |
NPY2R_HUMAN | [view interactions] | Low throughput | no | no |
PAHO_HUMAN | [view interactions] | Low throughput | no | no |
NPY4R_HUMAN | [view interactions] | Low throughput | no | yes |
AGRB2_HUMAN | [view interactions] | Low throughput | no | no |
NCF2_HUMAN | [view interactions] | Low throughput | no | no |
GBG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
GBG1_HUMAN | [view interactions] | Low throughput | no | no |
RGS4_HUMAN | [view interactions] | Low throughput | no | no |
GPSM3_HUMAN | [view interactions] | Low throughput | no | no |
MTR1A_HUMAN | [view interactions] | Low throughput | no | no |
MTR1B_HUMAN | [view interactions] | Low throughput | no | yes |
CXCR4_HUMAN | [view interactions] | Low throughput | no | no |
ACKR3_HUMAN | [view interactions] | Low throughput | no | no |
CNR1_HUMAN | [view interactions] | Low throughput | no | yes |
RGS19_HUMAN | [view interactions] | Low throughput | no | yes |
S1PR1_HUMAN | [view interactions] | Low throughput | no | no |
RGS20_HUMAN | [view interactions] | Low throughput | no | no |
GP143_HUMAN | [view interactions] | Low throughput | no | yes |
CRFR1_HUMAN | [view interactions] | Low throughput | no | yes |
RGS5_HUMAN | [view interactions] | Low throughput | no | no |
IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PRGR_HUMAN | [view interactions] | Low throughput | no | no |
PTH1R_HUMAN | [view interactions] | Low throughput | no | no |
PI2R_HUMAN | [view interactions] | Low throughput | no | no |
GPSM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PPP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
PGFRA_HUMAN | [view interactions] | Low throughput | no | no |
FGFR1_HUMAN | [view interactions] | Low throughput | no | yes |
NGB_HUMAN | [view interactions] | Low throughput | no | yes |
RGS18_HUMAN | [view interactions] | Low throughput | no | yes |
EPOR_HUMAN | [view interactions] | Low throughput | no | no |
RASD1_HUMAN | [view interactions] | Low throughput | no | yes |
RGS10_HUMAN | [view interactions] | Low throughput | no | yes |
RGS16_HUMAN | [view interactions] | Low throughput | no | no |
SMO_HUMAN | [view interactions] | Low throughput | no | yes |
GBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DRD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ADRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
ADCY5_HUMAN | [view interactions] | Low throughput | no | no |
NUCB1_HUMAN | [view interactions] | High throughput | no | yes |
RAGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THAP7_HUMAN | [view interactions] | High throughput | no | no |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IQCB1_HUMAN | [view interactions] | High throughput | no | no |
DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYO19_HUMAN | [view interactions] | High throughput | no | yes |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBG5_HUMAN | [view interactions] | High throughput | no | no |
MTHR_HUMAN | [view interactions] | High throughput | no | yes |
GNAI3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNAT3_HUMAN | [view interactions] | High throughput | no | no |
GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBG4_HUMAN | [view interactions] | High throughput | no | no |
OCRL_HUMAN | [view interactions] | High throughput | no | yes |
KPCD1_HUMAN | [view interactions] | High throughput | no | yes |
ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
COX15_HUMAN | [view interactions] | High throughput | no | yes |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APBB1_HUMAN | [view interactions] | High throughput | no | yes |
BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STK3_HUMAN | [view interactions] | High throughput | no | yes |
HASP_HUMAN | [view interactions] | High throughput | no | yes |
PAK5_HUMAN | [view interactions] | High throughput | no | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
CD81_HUMAN | [view interactions] | High throughput | no | no |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
RGS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCP2_HUMAN | [view interactions] | High throughput | no | no |
CBX1_HUMAN | [view interactions] | High throughput | no | yes |
HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
TRI69_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
CEP76_HUMAN | [view interactions] | High throughput | no | yes |
DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PCKGC_HUMAN | [view interactions] | High throughput | no | no |
NCF1_HUMAN | [view interactions] | High throughput | no | no |
UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SVIL_HUMAN | [view interactions] | High throughput | no | yes |
RAD52_HUMAN | [view interactions] | High throughput | no | no |
ATP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBG10_HUMAN | [view interactions] | High throughput | no | no |
GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PDE3B_HUMAN | [view interactions] | High throughput | no | no |
ABCA3_HUMAN | [view interactions] | High throughput | no | yes |
DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VPP2_HUMAN | [view interactions] | High throughput | no | yes |
CNEP1_HUMAN | [view interactions] | High throughput | no | yes |
GLI1_HUMAN | [view interactions] | High throughput | no | no |
DUS22_HUMAN | [view interactions] | High throughput | no | yes |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RN138_HUMAN | [view interactions] | High throughput | no | no |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GAB1_HUMAN | [view interactions] | High throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DUS6_HUMAN | [view interactions] | High throughput | no | yes |
EYA4_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
EMC1_HUMAN | [view interactions] | High throughput | no | yes |
EMC5_HUMAN | [view interactions] | High throughput | no | yes |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECT2_HUMAN | [view interactions] | High throughput | no | no |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
KIF23_HUMAN | [view interactions] | High throughput | no | yes |
PRC1_HUMAN | [view interactions] | High throughput | no | yes |
NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
GBG8_HUMAN | [view interactions] | High throughput | no | no |
SPN1_HUMAN | [view interactions] | High throughput | no | yes |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
FURIN_HUMAN | [view interactions] | High throughput | no | yes |
DPP4_HUMAN | [view interactions] | High throughput | no | no |
BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
CLC4D_HUMAN | [view interactions] | High throughput | no | no |
ACE2_HUMAN | [view interactions] | High throughput | no | no |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNAI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
GBB3_HUMAN | [view interactions] | High throughput | no | yes |
GBG11_HUMAN | [view interactions] | High throughput | no | no |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PI3R4_HUMAN | [view interactions] | High throughput | no | yes |
LAT1_HUMAN | [view interactions] | High throughput | no | yes |
GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RGS9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CXCR3_HUMAN | [view interactions] | Computational | no | no |
DRA_HUMAN | [view interactions] | Computational | no | no |
PE2R3_HUMAN | [view interactions] | Computational | no | no |
CD3E_HUMAN | [view interactions] | Computational | no | no |
RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SSR2_HUMAN | [view interactions] | Computational | no | yes |
PLF4_HUMAN | [view interactions] | Computational | no | no |
PAR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
EDNRB_HUMAN | [view interactions] | Computational | no | no |
AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CD4_HUMAN | [view interactions] | Computational | no | no |
PLCB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY6_HUMAN | [view interactions] | Computational | no | yes |
RGS3_HUMAN | [view interactions] | Computational | no | no |
ADCY7_HUMAN | [view interactions] | Computational | no | yes |
ANGT_HUMAN | [view interactions] | Computational | no | no |
ADRB3_HUMAN | [view interactions] | Computational | no | no |
VAMP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
BKRB2_HUMAN | [view interactions] | Computational | no | yes |
PI3R5_HUMAN | [view interactions] | Computational | no | no |
PAXI_HUMAN | [view interactions] | Computational | no | yes |
PAQR5_HUMAN | [view interactions] | Computational | no | no |
GNAS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RL3R2_HUMAN | [view interactions] | Computational | no | no |
PLCG1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
DRB1_HUMAN | [view interactions] | Computational | no | no |
P2Y12_HUMAN | [view interactions] | Computational | no | no |
LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CD3D_HUMAN | [view interactions] | Computational | no | no |
SDF1_HUMAN | [view interactions] | Computational | no | no |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
INS_HUMAN | [view interactions] | Computational | no | no |
EDN1_HUMAN | [view interactions] | Computational | no | no |
RGS8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY9_HUMAN | [view interactions] | Computational | no | yes |
RPGF4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAT2_HUMAN | [view interactions] | Computational | no | no |
SYT5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MK14_HUMAN | [view interactions] | Computational | no | yes |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PAR4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CASR_HUMAN | [view interactions] | Computational | no | no |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GNA11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY3_HUMAN | [view interactions] | Computational | no | yes |
STXB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PTN11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
BCAR1_HUMAN | [view interactions] | Computational | no | yes |
GNA15_HUMAN | [view interactions] | Computational | no | yes |
AGTR2_HUMAN | [view interactions] | Computational | no | no |
ADCY4_HUMAN | [view interactions] | Computational | no | yes |
CD3G_HUMAN | [view interactions] | Computational | no | no |
THRB_HUMAN | [view interactions] | Computational | no | no |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PI3R6_HUMAN | [view interactions] | Computational | no | yes |
RGSL_HUMAN | [view interactions] | Computational | no | no |
CD3Z_HUMAN | [view interactions] | Computational | no | no |
SNP25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
OXYR_HUMAN | [view interactions] | Computational | no | no |
RL3R1_HUMAN | [view interactions] | Computational | no | no |
NOS3_HUMAN | [view interactions] | Computational | no | no |
PHLP_HUMAN | [view interactions] | Computational | no | yes |
RGS22_HUMAN | [view interactions] | Computational | no | no |
ADCY2_HUMAN | [view interactions] | Computational | no | yes |
FAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRM3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
MK08_HUMAN | [view interactions] | Computational | no | yes |
FAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNAZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EGF_HUMAN | [view interactions] | Computational | no | no |
P85A_HUMAN | [view interactions] | Computational | no | yes |
S1PR4_HUMAN | [view interactions] | Computational | no | no |
RGS7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PK3CG_HUMAN | [view interactions] | Computational | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
STX1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GNA14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RPGF3_HUMAN | [view interactions] | Computational | no | yes |
AA1R_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GNAQ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
M3K7_HUMAN | [view interactions] | Computational | no | yes |
ADCY1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
GNAT1_HUMAN | [view interactions] | Computational | no | no |
OPRD_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ADRB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |