Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SMS_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

May enhance low-glucose-induced glucagon release by pancreatic alpha cells . This effect may be mediated by binding to GPR107 and PKA activation . May regulate cardiac contractile function . May compromise cardiomyocyte viability . In the central nervous system, may impair memory retention and may affect hippocampal excitability . May also have anxiolytic and anorexigenic effects . May play a role in arterial pressure regulation . May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (PubMed). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
58 Phe Leu Intellectualdevelopmentaldisorder,X-linked,syndromic,Snyder-Robinsontype(MRXSSR) -
56 Gly Ser Intellectualdevelopmentaldisorder,X-linked,syndromic,Snyder-Robinsontype(MRXSSR) -
67 Gly Glu Intellectualdevelopmentaldisorder,X-linked,syndromic,Snyder-Robinsontype(MRXSSR) -
132 Val Gly Intellectualdevelopmentaldisorder,X-linked,syndromic,Snyder-Robinsontype(MRXSSR) -
328 Tyr Cys Intellectualdevelopmentaldisorder,X-linked,syndromic,Snyder-Robinsontype(MRXSSR) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SMS_HUMAN
GO:0048018 receptor ligand activity 44.4444 4 yes
GO:0005179 hormone activity 33.3333 5 yes
GO:0046872 metal ion binding 33.3333 4 no
GO:0005509 calcium ion binding 22.2222 5 no
GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration 22.2222 6 no
GO:0099534 calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration 22.2222 7 no
GO:0004930 G protein-coupled receptor activity 22.2222 4 no
GO:0001664 G protein-coupled receptor binding 22.2222 4 no
GO:0046914 transition metal ion binding 22.2222 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SMS_HUMAN
GO:0010646 regulation of cell communication 77.7778 4 no
GO:0050804 modulation of chemical synaptic transmission 66.6667 5 no
GO:0099177 regulation of trans-synaptic signaling 66.6667 4 no
GO:0042127 regulation of cell population proliferation 66.6667 4 yes
GO:0048523 negative regulation of cellular process 66.6667 4 yes
GO:0051049 regulation of transport 55.5556 4 no
GO:0051094 positive regulation of developmental process 55.5556 4 no
GO:0051128 regulation of cellular component organization 55.5556 4 no
GO:0051223 regulation of protein transport 55.5556 5 no
GO:0051240 positive regulation of multicellular organismal process 55.5556 4 no
GO:0051241 negative regulation of multicellular organismal process 55.5556 4 no
GO:0060255 regulation of macromolecule metabolic process 55.5556 4 no
GO:0060341 regulation of cellular localization 55.5556 4 no
GO:0060548 negative regulation of cell death 55.5556 5 no
GO:0070201 regulation of establishment of protein localization 55.5556 6 no
GO:0080134 regulation of response to stress 55.5556 4 no
GO:0010243 response to organonitrogen compound 55.5556 4 yes
GO:0001817 regulation of cytokine production 55.5556 4 no
GO:0009892 negative regulation of metabolic process 55.5556 4 no
GO:0009893 positive regulation of metabolic process 55.5556 4 no
GO:0009966 regulation of signal transduction 55.5556 4 no
GO:0009967 positive regulation of signal transduction 55.5556 5 no
GO:0010468 regulation of gene expression 55.5556 5 no
GO:0010605 negative regulation of macromolecule metabolic process 55.5556 5 no
GO:0010647 positive regulation of cell communication 55.5556 5 no
GO:0010648 negative regulation of cell communication 55.5556 5 no
GO:0010941 regulation of cell death 55.5556 4 no
GO:0023056 positive regulation of signaling 55.5556 4 no
GO:0023057 negative regulation of signaling 55.5556 4 no
GO:0031347 regulation of defense response 55.5556 5 no
GO:0032101 regulation of response to external stimulus 55.5556 4 no
GO:0032880 regulation of protein localization 55.5556 5 no
GO:0040014 regulation of multicellular organism growth 55.5556 4 no
GO:0044057 regulation of system process 55.5556 4 no
GO:0048522 positive regulation of cellular process 55.5556 4 no
GO:0048584 positive regulation of response to stimulus 55.5556 4 no
GO:0048585 negative regulation of response to stimulus 55.5556 4 no
GO:0048638 regulation of developmental growth 55.5556 4 no
GO:0048639 positive regulation of developmental growth 44.4444 5 no
GO:0050708 regulation of protein secretion 44.4444 5 no
GO:0050727 regulation of inflammatory response 44.4444 5 no
GO:0051046 regulation of secretion 44.4444 5 no
GO:0051050 positive regulation of transport 44.4444 4 no
GO:0051130 positive regulation of cellular component organization 44.4444 5 no
GO:0071310 cellular response to organic substance 44.4444 4 no
GO:0080090 regulation of primary metabolic process 44.4444 4 no
GO:1902531 regulation of intracellular signal transduction 44.4444 5 no
GO:1902533 positive regulation of intracellular signal transduction 44.4444 6 no
GO:1903530 regulation of secretion by cell 44.4444 4 no
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 44.4444 5 no
GO:2000026 regulation of multicellular organismal development 44.4444 4 no
GO:0006873 cellular ion homeostasis 44.4444 4 no
GO:0006874 cellular calcium ion homeostasis 44.4444 7 no
GO:0006875 cellular metal ion homeostasis 44.4444 6 no
GO:0030003 cellular cation homeostasis 44.4444 5 no
GO:0048878 chemical homeostasis 44.4444 4 no
GO:0050801 ion homeostasis 44.4444 5 no
GO:0055065 metal ion homeostasis 44.4444 7 no
GO:0055074 calcium ion homeostasis 44.4444 8 no
GO:0055080 cation homeostasis 44.4444 6 no
GO:0072503 cellular divalent inorganic cation homeostasis 44.4444 6 no
GO:0072507 divalent inorganic cation homeostasis 44.4444 7 no
GO:0098771 inorganic ion homeostasis 44.4444 6 no
GO:1900271 regulation of long-term synaptic potentiation 44.4444 4 no
GO:0008285 negative regulation of cell population proliferation 44.4444 5 yes
GO:0014070 response to organic cyclic compound 44.4444 4 yes
GO:0030334 regulation of cell migration 44.4444 5 yes
GO:2000145 regulation of cell motility 44.4444 4 yes
GO:0050807 regulation of synapse organization 44.4444 5 no
GO:0050890 cognition 44.4444 4 no
GO:0008284 positive regulation of cell population proliferation 44.4444 5 no
GO:0010629 negative regulation of gene expression 44.4444 6 no
GO:1903828 negative regulation of protein localization 44.4444 5 no
GO:0031323 regulation of cellular metabolic process 44.4444 4 no
GO:0031325 positive regulation of cellular metabolic process 44.4444 5 no
GO:0031348 negative regulation of defense response 44.4444 5 no
GO:0032102 negative regulation of response to external stimulus 44.4444 5 no
GO:0032651 regulation of interleukin-1 beta production 44.4444 6 no
GO:0032652 regulation of interleukin-1 production 44.4444 5 no
GO:0032680 regulation of tumor necrosis factor production 44.4444 6 no
GO:0042981 regulation of apoptotic process 44.4444 6 no
GO:0043067 regulation of programmed cell death 44.4444 5 no
GO:0043408 regulation of MAPK cascade 44.4444 6 no
GO:0043410 positive regulation of MAPK cascade 44.4444 7 no
GO:0045927 positive regulation of growth 44.4444 4 no
GO:0050678 regulation of epithelial cell proliferation 33.3333 5 no
GO:0050679 positive regulation of epithelial cell proliferation 33.3333 6 no
GO:0050728 negative regulation of inflammatory response 33.3333 6 no
GO:0051047 positive regulation of secretion 33.3333 5 no
GO:0051093 negative regulation of developmental process 33.3333 4 no
GO:0051171 regulation of nitrogen compound metabolic process 33.3333 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0051174 regulation of phosphorus metabolic process 33.3333 5 no
GO:0051222 positive regulation of protein transport 33.3333 5 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0051252 regulation of RNA metabolic process 33.3333 5 no
GO:0051254 positive regulation of RNA metabolic process 33.3333 6 no
GO:0051338 regulation of transferase activity 33.3333 4 no
GO:0051347 positive regulation of transferase activity 33.3333 5 no
GO:0051726 regulation of cell cycle 33.3333 4 no
GO:0062012 regulation of small molecule metabolic process 33.3333 4 no
GO:0062013 positive regulation of small molecule metabolic process 33.3333 5 no
GO:0070372 regulation of ERK1 and ERK2 cascade 33.3333 7 no
GO:0070374 positive regulation of ERK1 and ERK2 cascade 33.3333 8 no
GO:0071417 cellular response to organonitrogen compound 33.3333 4 no
GO:0090068 positive regulation of cell cycle process 33.3333 6 no
GO:0090257 regulation of muscle system process 33.3333 5 no
GO:1901652 response to peptide 33.3333 4 no
GO:1901653 cellular response to peptide 33.3333 5 no
GO:1901699 cellular response to nitrogen compound 33.3333 4 no
GO:1901701 cellular response to oxygen-containing compound 33.3333 4 no
GO:1902680 positive regulation of RNA biosynthetic process 33.3333 7 no
GO:1903506 regulation of nucleic acid-templated transcription 33.3333 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 33.3333 8 no
GO:1903532 positive regulation of secretion by cell 33.3333 5 no
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 33.3333 6 no
GO:1903829 positive regulation of protein localization 33.3333 5 no
GO:1904951 positive regulation of establishment of protein localization 33.3333 6 no
GO:2001141 regulation of RNA biosynthetic process 33.3333 6 no
GO:0002791 regulation of peptide secretion 33.3333 6 no
GO:0002792 negative regulation of peptide secretion 33.3333 6 no
GO:0007613 memory 33.3333 4 no
GO:0030030 cell projection organization 33.3333 4 no
GO:0040013 negative regulation of locomotion 33.3333 4 no
GO:0040018 positive regulation of multicellular organism growth 33.3333 5 no
GO:0043269 regulation of ion transport 33.3333 5 no
GO:0007268 chemical synaptic transmission 33.3333 6 yes
GO:0046676 negative regulation of insulin secretion 33.3333 7 no
GO:0046883 regulation of hormone secretion 33.3333 4 no
GO:0046888 negative regulation of hormone secretion 33.3333 5 no
GO:0046903 secretion 33.3333 4 no
GO:0098916 anterograde trans-synaptic signaling 33.3333 5 yes
GO:0048521 negative regulation of behavior 33.3333 5 no
GO:0099537 trans-synaptic signaling 33.3333 4 yes
GO:0001818 negative regulation of cytokine production 33.3333 5 no
GO:0050709 negative regulation of protein secretion 33.3333 6 no
GO:0001932 regulation of protein phosphorylation 33.3333 7 no
GO:0001934 positive regulation of protein phosphorylation 33.3333 8 no
GO:0050795 regulation of behavior 33.3333 4 no
GO:0050796 regulation of insulin secretion 33.3333 6 no
GO:0006355 regulation of DNA-templated transcription 33.3333 6 no
GO:0006357 regulation of transcription by RNA polymerase II 33.3333 7 no
GO:0051048 negative regulation of secretion 33.3333 5 no
GO:0051051 negative regulation of transport 33.3333 4 no
GO:0051224 negative regulation of protein transport 33.3333 5 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0009891 positive regulation of biosynthetic process 33.3333 5 no
GO:0009968 negative regulation of signal transduction 33.3333 5 no
GO:0060123 regulation of growth hormone secretion 33.3333 6 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 33.3333 6 no
GO:0071702 organic substance transport 33.3333 4 no
GO:0010562 positive regulation of phosphorus metabolic process 33.3333 6 no
GO:0090087 regulation of peptide transport 33.3333 5 no
GO:0010564 regulation of cell cycle process 33.3333 5 no
GO:0090276 regulation of peptide hormone secretion 33.3333 5 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0090278 negative regulation of peptide hormone secretion 33.3333 6 no
GO:0010628 positive regulation of gene expression 33.3333 6 no
GO:0099170 postsynaptic modulation of chemical synaptic transmission 33.3333 6 no
GO:1903522 regulation of blood circulation 33.3333 5 no
GO:1903531 negative regulation of secretion by cell 33.3333 5 no
GO:1904950 negative regulation of establishment of protein localization 33.3333 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 33.3333 5 no
GO:0019220 regulation of phosphate metabolic process 33.3333 6 no
GO:0031644 regulation of nervous system process 33.3333 5 no
GO:0032103 positive regulation of response to external stimulus 33.3333 5 no
GO:0032675 regulation of interleukin-6 production 33.3333 5 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0044087 regulation of cellular component biogenesis 33.3333 4 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0031328 positive regulation of cellular biosynthetic process 33.3333 6 no
GO:0051963 regulation of synapse assembly 33.3333 6 no
GO:0097435 supramolecular fiber organization 33.3333 4 no
GO:0099175 regulation of postsynapse organization 33.3333 6 no
GO:1901888 regulation of cell junction assembly 33.3333 5 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0032691 negative regulation of interleukin-1 beta production 33.3333 7 no
GO:0032692 negative regulation of interleukin-1 production 33.3333 6 no
GO:0032720 negative regulation of tumor necrosis factor production 33.3333 7 no
GO:0033674 positive regulation of kinase activity 33.3333 6 no
GO:0034762 regulation of transmembrane transport 33.3333 4 no
GO:0042325 regulation of phosphorylation 33.3333 7 no
GO:0042327 positive regulation of phosphorylation 33.3333 8 no
GO:0043066 negative regulation of apoptotic process 33.3333 7 no
GO:0043069 negative regulation of programmed cell death 33.3333 6 no
GO:0043085 positive regulation of catalytic activity 33.3333 4 no
GO:0043549 regulation of kinase activity 33.3333 5 no
GO:0045595 regulation of cell differentiation 33.3333 4 no
GO:0045597 positive regulation of cell differentiation 33.3333 5 no
GO:0045787 positive regulation of cell cycle 33.3333 5 no
GO:0045859 regulation of protein kinase activity 33.3333 6 no
GO:0045860 positive regulation of protein kinase activity 33.3333 7 no
GO:0045893 positive regulation of DNA-templated transcription 33.3333 7 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 33.3333 6 no
GO:0045937 positive regulation of phosphate metabolic process 33.3333 7 no
GO:0045944 positive regulation of transcription by RNA polymerase II 33.3333 8 no
GO:0050714 positive regulation of protein secretion 22.2222 6 no
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 22.2222 8 no
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 22.2222 9 no
GO:0050865 regulation of cell activation 22.2222 4 no
GO:0050867 positive regulation of cell activation 22.2222 5 no
GO:0051099 positive regulation of binding 22.2222 4 no
GO:0051129 negative regulation of cellular component organization 22.2222 5 no
GO:0051248 negative regulation of protein metabolic process 22.2222 6 no
GO:0060284 regulation of cell development 22.2222 5 no
GO:1900542 regulation of purine nucleotide metabolic process 22.2222 6 no
GO:1900544 positive regulation of purine nucleotide metabolic process 22.2222 7 no
GO:1902991 regulation of amyloid precursor protein catabolic process 22.2222 6 no
GO:1903578 regulation of ATP metabolic process 22.2222 7 no
GO:1903580 positive regulation of ATP metabolic process 22.2222 8 no
GO:1904645 response to amyloid-beta 22.2222 5 no
GO:1904646 cellular response to amyloid-beta 22.2222 6 no
GO:2000112 regulation of cellular macromolecule biosynthetic process 22.2222 6 no
GO:2000147 positive regulation of cell motility 22.2222 5 no
GO:0051480 regulation of cytosolic calcium ion concentration 22.2222 8 no
GO:0060249 anatomical structure homeostasis 22.2222 4 no
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 22.2222 4 no
GO:0001819 positive regulation of cytokine production 22.2222 5 no
GO:0002090 regulation of receptor internalization 22.2222 7 no
GO:0002092 positive regulation of receptor internalization 22.2222 7 no
GO:0002793 positive regulation of peptide secretion 22.2222 6 no
GO:0006869 lipid transport 22.2222 5 no
GO:0006897 endocytosis 22.2222 5 no
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 22.2222 4 no
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 22.2222 5 no
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 22.2222 5 no
GO:0007409 axonogenesis 22.2222 8 no
GO:0007416 synapse assembly 22.2222 6 no
GO:0007612 learning 22.2222 4 no
GO:0007616 long-term memory 22.2222 5 no
GO:0008277 regulation of G protein-coupled receptor signaling pathway 22.2222 5 no
GO:0008306 associative learning 22.2222 5 no
GO:0008344 adult locomotory behavior 22.2222 4 no
GO:0008542 visual learning 22.2222 4 no
GO:0009416 response to light stimulus 22.2222 4 no
GO:0010038 response to metal ion 22.2222 4 no
GO:0016192 vesicle-mediated transport 22.2222 4 no
GO:0022607 cellular component assembly 22.2222 4 no
GO:0022898 regulation of transmembrane transporter activity 22.2222 4 no
GO:0030100 regulation of endocytosis 22.2222 5 no
GO:0032412 regulation of ion transmembrane transporter activity 22.2222 5 no
GO:0032990 cell part morphogenesis 22.2222 4 no
GO:0033604 negative regulation of catecholamine secretion 22.2222 6 no
GO:0034329 cell junction assembly 22.2222 5 no
GO:0034330 cell junction organization 22.2222 4 no
GO:0034765 regulation of ion transmembrane transport 22.2222 5 no
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 22.2222 5 no
GO:0042749 regulation of circadian sleep/wake cycle 22.2222 4 no
GO:0042754 negative regulation of circadian rhythm 22.2222 4 no
GO:0043271 negative regulation of ion transport 22.2222 5 no
GO:0045187 regulation of circadian sleep/wake cycle, sleep 22.2222 5 no
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway 22.2222 6 no
GO:0045807 positive regulation of endocytosis 22.2222 5 no
GO:0046717 acid secretion 22.2222 5 no
GO:0046887 positive regulation of hormone secretion 22.2222 5 no
GO:0031667 response to nutrient levels 22.2222 4 yes
GO:0033993 response to lipid 22.2222 4 yes
GO:0048168 regulation of neuronal synaptic plasticity 22.2222 4 no
GO:0048169 regulation of long-term neuronal synaptic plasticity 22.2222 5 no
GO:0048259 regulation of receptor-mediated endocytosis 22.2222 6 no
GO:0048545 response to steroid hormone 22.2222 4 yes
GO:0048260 positive regulation of receptor-mediated endocytosis 22.2222 6 no
GO:0048812 neuron projection morphogenesis 22.2222 7 no
GO:0048858 cell projection morphogenesis 22.2222 5 no
GO:0050433 regulation of catecholamine secretion 22.2222 5 no
GO:0050776 regulation of immune response 22.2222 4 no
GO:0002684 positive regulation of immune system process 22.2222 4 no
GO:0006109 regulation of carbohydrate metabolic process 22.2222 5 no
GO:0050806 positive regulation of synaptic transmission 22.2222 5 no
GO:0006110 regulation of glycolytic process 22.2222 6 no
GO:0006140 regulation of nucleotide metabolic process 22.2222 5 no
GO:0050808 synapse organization 22.2222 5 no
GO:0007346 regulation of mitotic cell cycle 22.2222 5 no
GO:0051336 regulation of hydrolase activity 22.2222 4 no
GO:0051896 regulation of protein kinase B signaling 22.2222 6 no
GO:0051952 regulation of amine transport 22.2222 5 no
GO:0051953 negative regulation of amine transport 22.2222 5 no
GO:0009894 regulation of catabolic process 22.2222 4 no
GO:0051960 regulation of nervous system development 22.2222 5 no
GO:0009896 positive regulation of catabolic process 22.2222 5 no
GO:0051962 positive regulation of nervous system development 22.2222 5 no
GO:0060078 regulation of postsynaptic membrane potential 22.2222 4 no
GO:0060079 excitatory postsynaptic potential 22.2222 5 no
GO:0060124 positive regulation of growth hormone secretion 22.2222 7 no
GO:0060627 regulation of vesicle-mediated transport 22.2222 4 no
GO:0090277 positive regulation of peptide hormone secretion 22.2222 6 no
GO:0090325 regulation of locomotion involved in locomotory behavior 22.2222 4 no
GO:0010639 negative regulation of organelle organization 22.2222 6 no
GO:0120039 plasma membrane bounded cell projection morphogenesis 22.2222 6 no
GO:1900273 positive regulation of long-term synaptic potentiation 22.2222 5 no
GO:0010821 regulation of mitochondrion organization 22.2222 6 no
GO:0010823 negative regulation of mitochondrion organization 22.2222 7 no
GO:1904062 regulation of cation transmembrane transport 22.2222 6 no
GO:2001257 regulation of cation channel activity 22.2222 6 no
GO:0019216 regulation of lipid metabolic process 22.2222 5 no
GO:0019752 carboxylic acid metabolic process 22.2222 5 no
GO:0031175 neuron projection development 22.2222 6 no
GO:0030335 positive regulation of cell migration 22.2222 6 no
GO:0036211 protein modification process 22.2222 4 no
GO:0043412 macromolecule modification 22.2222 4 no
GO:0045834 positive regulation of lipid metabolic process 22.2222 5 no
GO:0031329 regulation of cellular catabolic process 22.2222 5 no
GO:0031331 positive regulation of cellular catabolic process 22.2222 6 no
GO:0120036 plasma membrane bounded cell projection organization 22.2222 5 no
GO:0001936 regulation of endothelial cell proliferation 22.2222 6 no
GO:0001938 positive regulation of endothelial cell proliferation 22.2222 7 no
GO:0002790 peptide secretion 22.2222 5 no
GO:0006937 regulation of muscle contraction 22.2222 6 no
GO:0032147 activation of protein kinase activity 22.2222 8 no
GO:0006940 regulation of smooth muscle contraction 22.2222 7 no
GO:0007015 actin filament organization 22.2222 5 no
GO:0008154 actin polymerization or depolymerization 22.2222 6 no
GO:0008343 adult feeding behavior 22.2222 4 no
GO:0009914 hormone transport 22.2222 4 no
GO:0015833 peptide transport 22.2222 5 no
GO:0022603 regulation of anatomical structure morphogenesis 22.2222 4 no
GO:0023061 signal release 22.2222 4 no
GO:0033043 regulation of organelle organization 22.2222 5 no
GO:0030072 peptide hormone secretion 22.2222 6 no
GO:0030252 growth hormone secretion 22.2222 7 no
GO:0034248 regulation of cellular amide metabolic process 22.2222 5 no
GO:0032095 regulation of response to food 22.2222 7 no
GO:0032097 positive regulation of response to food 22.2222 8 no
GO:0032100 positive regulation of appetite 22.2222 4 no
GO:0040017 positive regulation of locomotion 22.2222 4 no
GO:0032104 regulation of response to extracellular stimulus 22.2222 5 no
GO:0032106 positive regulation of response to extracellular stimulus 22.2222 6 no
GO:0032107 regulation of response to nutrient levels 22.2222 6 no
GO:0032109 positive regulation of response to nutrient levels 22.2222 7 no
GO:0032715 negative regulation of interleukin-6 production 22.2222 6 no
GO:0042886 amide transport 22.2222 5 no
GO:0044058 regulation of digestive system process 22.2222 5 no
GO:0045765 regulation of angiogenesis 22.2222 5 no
GO:0045766 positive regulation of angiogenesis 22.2222 6 no
GO:0045933 positive regulation of muscle contraction 22.2222 5 no
GO:0043436 oxoacid metabolic process 22.2222 4 no
GO:0045987 positive regulation of smooth muscle contraction 22.2222 6 no
GO:0043467 regulation of generation of precursor metabolites and energy 22.2222 5 no
GO:0046879 hormone secretion 22.2222 5 no
GO:0043470 regulation of carbohydrate catabolic process 22.2222 5 no
GO:0048520 positive regulation of behavior 22.2222 5 no
GO:0051969 regulation of transmission of nerve impulse 22.2222 4 no
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 22.2222 5 no
GO:0060259 regulation of feeding behavior 22.2222 5 no
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 22.2222 6 no
GO:0060456 positive regulation of digestive system process 22.2222 5 no
GO:0071705 nitrogen compound transport 22.2222 4 no
GO:0120057 regulation of small intestinal transit 22.2222 6 no
GO:0045596 negative regulation of cell differentiation 22.2222 5 no
GO:0120058 positive regulation of small intestinal transit 22.2222 6 no
GO:1901342 regulation of vasculature development 22.2222 5 no
GO:1903670 regulation of sprouting angiogenesis 22.2222 6 no
GO:0045821 positive regulation of glycolytic process 22.2222 6 no
GO:1903672 positive regulation of sprouting angiogenesis 22.2222 7 no
GO:1903998 regulation of eating behavior 22.2222 6 no
GO:1904000 positive regulation of eating behavior 22.2222 7 no
GO:1904018 positive regulation of vasculature development 22.2222 5 no
GO:0045913 positive regulation of carbohydrate metabolic process 22.2222 5 no
GO:1904304 regulation of gastro-intestinal system smooth muscle contraction 22.2222 8 no
GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction 22.2222 7 no
GO:1904347 regulation of small intestine smooth muscle contraction 22.2222 9 no
GO:1904349 positive regulation of small intestine smooth muscle contraction 22.2222 8 no
GO:1905333 regulation of gastric motility 22.2222 6 no
GO:0045981 positive regulation of nucleotide metabolic process 22.2222 6 no
GO:1905562 regulation of vascular endothelial cell proliferation 22.2222 7 no
GO:1905564 positive regulation of vascular endothelial cell proliferation 22.2222 8 no
GO:2000253 positive regulation of feeding behavior 22.2222 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PDIA2_HUMAN [view interactions] Low throughput no no
CREB1_HUMAN [view interactions] Low throughput no yes
SSR3_HUMAN [view interactions] Low throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
VIP_HUMAN [view interactions] Computational no no
CCKN_HUMAN [view interactions] Computational no yes
DCE1_HUMAN [view entry] [view interactions] Computational yes yes
TRH_HUMAN [view interactions] Computational no no
SSR4_HUMAN [view interactions] Computational no no
GRP_HUMAN [view interactions] Computational no no
IGF1_HUMAN [view entry] [view interactions] Computational yes no
GLUC_HUMAN [view interactions] Computational no no
CRF_HUMAN [view interactions] Computational no no
GALA_HUMAN [view interactions] Computational no no
SSR1_HUMAN [view interactions] Computational no no
CORT_HUMAN [view interactions] Computational no no
TKN1_HUMAN [view interactions] Computational no yes
SSR2_HUMAN [view interactions] Computational no yes
GHSR_HUMAN [view entry] [view interactions] Computational yes no
SNED1_HUMAN [view interactions] Computational no yes
GAST_HUMAN [view interactions] Computational no no
CALB2_HUMAN [view entry] [view interactions] Computational yes yes
GHRL_HUMAN [view entry] [view interactions] Computational yes no
NPY_HUMAN [view interactions] Computational no yes
MECP2_HUMAN [view interactions] Computational no yes
CMGA_HUMAN [view interactions] Computational no yes
NEUT_HUMAN [view interactions] Computational no no
PAHO_HUMAN [view interactions] Computational no no
COLI_HUMAN [view interactions] Computational no no
CALC_HUMAN [view interactions] Computational no no
DRD2_HUMAN [view entry] [view interactions] Computational yes no
MOTI_HUMAN [view interactions] Computational no no
NGN3_HUMAN [view interactions] Computational no no
SECR_HUMAN [view interactions] Computational no no
PRVA_HUMAN [view interactions] Computational no yes
INS_HUMAN [view interactions] Computational no no
SSR5_HUMAN [view interactions] Computational no no
SLIB_HUMAN [view interactions] Computational no no
CALB1_HUMAN [view entry] [view interactions] Computational yes yes