DCTN3_HUMAN
Evidence for PS localization
Functions
Together with dynein may be involved in spindle assembly and cytokinesis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DCTN3_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 30.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 30.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.0000 | 4 | no |
| GO:0005524 | ATP binding | 26.6667 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 26.6667 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 26.6667 | 5 | no |
| GO:0003723 | RNA binding | 25.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DCTN3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 48.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 46.6667 | 4 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 38.3333 | 4 | no |
| GO:0033043 | regulation of organelle organization | 36.6667 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 36.6667 | 4 | no |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 30.0000 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 28.3333 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 28.3333 | 6 | no |
| GO:0080090 | regulation of primary metabolic process | 28.3333 | 4 | no |
| GO:0010646 | regulation of cell communication | 28.3333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.6667 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 26.6667 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0007010 | cytoskeleton organization | 25.0000 | 5 | no |
| GO:0008104 | protein localization | 23.3333 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.3333 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 23.3333 | 4 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 23.3333 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.3333 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 21.6667 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 21.6667 | 5 | no |
| GO:0032880 | regulation of protein localization | 21.6667 | 5 | no |
| GO:0051049 | regulation of transport | 21.6667 | 4 | no |
| GO:0010468 | regulation of gene expression | 21.6667 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21.6667 | 5 | no |
| GO:0030030 | cell projection organization | 21.6667 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 21.6667 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 21.6667 | 5 | no |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 3.3333 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DCTN3_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 5.0000 | 3 | no |
| DOID:1289 | neurodegenerative disease | 3.3333 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LRA25_HUMAN | [view interactions] | High throughput | no | yes |
| ZN398_HUMAN | [view interactions] | High throughput | no | no |
| SYMPK_HUMAN | [view interactions] | High throughput | no | yes |
| AQ12B_HUMAN | [view interactions] | High throughput | no | no |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP19_HUMAN | [view interactions] | High throughput | no | no |
| PAF1_HUMAN | [view interactions] | High throughput | no | yes |
| RRP44_HUMAN | [view interactions] | High throughput | no | yes |
| CBWD1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| DYLT3_HUMAN | [view interactions] | High throughput | no | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| NUP85_HUMAN | [view interactions] | High throughput | no | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TB182_HUMAN | [view interactions] | High throughput | no | yes |
| NDEL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| PBX2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LZIC_HUMAN | [view interactions] | High throughput | no | no |
| US6NL_HUMAN | [view interactions] | High throughput | no | yes |
| MLEC_HUMAN | [view interactions] | High throughput | no | no |
| COR2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPA1P_HUMAN | [view interactions] | High throughput | no | yes |
| NFIB_HUMAN | [view interactions] | High throughput | no | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| LGMN_HUMAN | [view interactions] | High throughput | no | yes |
| ASTE1_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE295_HUMAN | [view interactions] | High throughput | no | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| Z286A_HUMAN | [view interactions] | High throughput | no | no |
| NMNA1_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTY_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PACN3_HUMAN | [view interactions] | High throughput | no | yes |
| KLH12_HUMAN | [view interactions] | High throughput | no | no |
| DCTN6_HUMAN | [view interactions] | High throughput | no | no |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| K2C79_HUMAN | [view interactions] | High throughput | no | no |
| TAF6_HUMAN | [view interactions] | High throughput | no | no |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DRC1_HUMAN | [view interactions] | High throughput | no | no |
| AN36B_HUMAN | [view interactions] | High throughput | no | no |
| RBM7_HUMAN | [view interactions] | High throughput | no | yes |
| MTREX_HUMAN | [view interactions] | High throughput | no | yes |
| HMGB2_HUMAN | [view interactions] | High throughput | no | yes |
| ARP10_HUMAN | [view interactions] | High throughput | no | no |
| M18BP_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCC2_HUMAN | [view interactions] | High throughput | no | yes |
| DLRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FWCH1_HUMAN | [view interactions] | High throughput | no | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| DAPK3_HUMAN | [view interactions] | High throughput | no | yes |
| CATC_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| DCTN5_HUMAN | [view interactions] | High throughput | no | yes |
| MTNB_HUMAN | [view interactions] | High throughput | no | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABC3B_HUMAN | [view interactions] | High throughput | no | no |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP1_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
| ASPM_HUMAN | [view interactions] | High throughput | no | no |
| PTHD1_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| PITX1_HUMAN | [view interactions] | High throughput | no | yes |
| PCH2_HUMAN | [view interactions] | High throughput | no | no |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| NUP54_HUMAN | [view interactions] | High throughput | no | yes |
| VP37C_HUMAN | [view interactions] | High throughput | no | yes |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| PHF19_HUMAN | [view interactions] | High throughput | no | no |
| THAP1_HUMAN | [view interactions] | High throughput | no | no |
| CSPP1_HUMAN | [view interactions] | High throughput | no | no |
| C4BPB_HUMAN | [view interactions] | High throughput | no | no |
| NMI_HUMAN | [view interactions] | High throughput | no | yes |
| GPS2_HUMAN | [view interactions] | High throughput | no | yes |
| CAH10_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L2_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| LRIF1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTA_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNMT1_HUMAN | [view interactions] | High throughput | no | no |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKBL1_HUMAN | [view interactions] | High throughput | no | no |
| TRY1_HUMAN | [view interactions] | High throughput | no | no |
| TFE2_HUMAN | [view interactions] | High throughput | no | no |
| TPD52_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAR1_HUMAN | [view interactions] | High throughput | no | yes |
| PR40A_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| CCNQ_HUMAN | [view interactions] | High throughput | no | yes |
| CA226_HUMAN | [view interactions] | High throughput | no | yes |
| PODO_HUMAN | [view interactions] | High throughput | no | no |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| RIC8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DB127_HUMAN | [view interactions] | High throughput | no | no |
| KLHL2_HUMAN | [view interactions] | High throughput | no | no |
| MS18A_HUMAN | [view interactions] | High throughput | no | yes |
| PDGFD_HUMAN | [view interactions] | High throughput | no | no |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| AROS_HUMAN | [view interactions] | High throughput | no | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| INAVA_HUMAN | [view interactions] | High throughput | no | yes |
| UB2L6_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| N42L1_HUMAN | [view interactions] | High throughput | no | yes |
| CCL4_HUMAN | [view interactions] | High throughput | no | no |
| ZG16B_HUMAN | [view interactions] | High throughput | no | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED22_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXL14_HUMAN | [view interactions] | High throughput | no | yes |
| CYTS_HUMAN | [view interactions] | High throughput | no | no |
| BIRC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP14_HUMAN | [view interactions] | High throughput | no | no |
| ABCF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| EDRF1_HUMAN | [view interactions] | High throughput | no | no |
| FOXK2_HUMAN | [view interactions] | High throughput | no | yes |
| I2BP1_HUMAN | [view interactions] | High throughput | no | yes |
| CTF18_HUMAN | [view interactions] | High throughput | no | no |
| TSP1_HUMAN | [view interactions] | High throughput | no | no |
| RGL3_HUMAN | [view interactions] | High throughput | no | yes |
| THUM3_HUMAN | [view interactions] | High throughput | no | yes |
| POMP_HUMAN | [view interactions] | High throughput | no | yes |
| MARH7_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK1_HUMAN | [view interactions] | High throughput | no | yes |
| SELO_HUMAN | [view interactions] | High throughput | no | yes |
| PDXD1_HUMAN | [view interactions] | High throughput | no | no |
| COASY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD1_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| VCIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KS6A4_HUMAN | [view interactions] | High throughput | no | yes |
| NACC2_HUMAN | [view interactions] | High throughput | no | yes |
| ARK72_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIPC_HUMAN | [view interactions] | High throughput | no | yes |
| RAD17_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYH5_HUMAN | [view interactions] | Computational | no | no |
| GCR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MCR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DNAL4_HUMAN | [view interactions] | Computational | no | yes |
| RBGPR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ANDR_HUMAN | [view interactions] | Computational | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYH11_HUMAN | [view interactions] | Computational | no | no |
| DYH17_HUMAN | [view interactions] | Computational | no | no |
| DYH2_HUMAN | [view interactions] | Computational | no | no |
| DNAL1_HUMAN | [view interactions] | Computational | no | no |
| DYH3_HUMAN | [view interactions] | Computational | no | no |
| HS90B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DNAI2_HUMAN | [view interactions] | Computational | no | no |
| HAP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYH12_HUMAN | [view interactions] | Computational | no | no |
| DYH6_HUMAN | [view interactions] | Computational | no | no |
| DYH7_HUMAN | [view interactions] | Computational | no | no |
| PRGR_HUMAN | [view interactions] | Computational | no | no |
| DYH9_HUMAN | [view interactions] | Computational | no | no |
| DYH1_HUMAN | [view interactions] | Computational | no | yes |
| DYH14_HUMAN | [view interactions] | Computational | no | no |
| RB3GP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |