BIRC6_HUMAN
Evidence for PS localization
Functions
Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in BIRC6_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 23.3333 | 4 | no |
| GO:0043168 | anion binding | 21.6667 | 4 | no |
| GO:0046872 | metal ion binding | 21.6667 | 5 | no |
| GO:0004842 | ubiquitin-protein transferase activity | 6.6667 | 4 | yes |
| GO:0016755 | aminoacyltransferase activity | 6.6667 | 4 | yes |
| GO:0004866 | endopeptidase inhibitor activity | 5.0000 | 5 | yes |
| GO:0004869 | cysteine-type endopeptidase inhibitor activity | 5.0000 | 6 | yes |
| GO:0030414 | peptidase inhibitor activity | 5.0000 | 4 | yes |
| GO:0061135 | endopeptidase regulator activity | 5.0000 | 4 | yes |
| GO:0061631 | ubiquitin conjugating enzyme activity | 3.3333 | 5 | yes |
| GO:0061650 | ubiquitin-like protein conjugating enzyme activity | 3.3333 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in BIRC6_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 55.0000 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 48.3333 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 48.3333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.3333 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 43.3333 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 41.6667 | 4 | yes |
| GO:0006996 | organelle organization | 41.6667 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 40.0000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | no |
| GO:0008104 | protein localization | 36.6667 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.0000 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.6667 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 30.0000 | 4 | no |
| GO:0009894 | regulation of catabolic process | 30.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 30.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.0000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.0000 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.0000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 30.0000 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 28.3333 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.3333 | 5 | no |
| GO:0022607 | cellular component assembly | 28.3333 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.6667 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.6667 | 4 | no |
| GO:0051049 | regulation of transport | 26.6667 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 25.0000 | 4 | yes |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 25.0000 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.3333 | 5 | no |
| GO:0031399 | regulation of protein modification process | 23.3333 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 23.3333 | 4 | no |
| GO:0015031 | protein transport | 23.3333 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.3333 | 5 | no |
| GO:0036211 | protein modification process | 21.6667 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 21.6667 | 5 | yes |
| GO:0043067 | regulation of programmed cell death | 21.6667 | 4 | yes |
| GO:0043412 | macromolecule modification | 21.6667 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 21.6667 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.6667 | 5 | no |
| GO:0007010 | cytoskeleton organization | 21.6667 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 20.0000 | 5 | yes |
| GO:0010564 | regulation of cell cycle process | 20.0000 | 5 | yes |
| GO:0010648 | negative regulation of cell communication | 20.0000 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 20.0000 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 20.0000 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 18.3333 | 4 | yes |
| GO:0006915 | apoptotic process | 18.3333 | 4 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 18.3333 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 16.6667 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 16.6667 | 5 | yes |
| GO:0032465 | regulation of cytokinesis | 15.0000 | 5 | yes |
| GO:0051302 | regulation of cell division | 15.0000 | 4 | yes |
| GO:0016310 | phosphorylation | 11.6667 | 5 | yes |
| GO:0043687 | post-translational protein modification | 10.0000 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 10.0000 | 6 | yes |
| GO:0006468 | protein phosphorylation | 10.0000 | 5 | yes |
| GO:0016567 | protein ubiquitination | 8.3333 | 8 | yes |
| GO:0032446 | protein modification by small protein conjugation | 8.3333 | 7 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 8.3333 | 5 | yes |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 6.6667 | 6 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 5.0000 | 6 | yes |
| GO:0060712 | spongiotrophoblast layer development | 3.3333 | 4 | yes |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 3.3333 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MP2K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLK1_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB8B_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KIF23_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RNF41_HUMAN | [view interactions] | Low throughput | no | yes |
| AURKB_HUMAN | [view interactions] | Low throughput | no | yes |
| GOGA4_HUMAN | [view interactions] | Low throughput | no | yes |
| HTRA2_HUMAN | [view interactions] | Low throughput | no | yes |
| DBLOH_HUMAN | [view interactions] | Low throughput | no | no |
| CASP9_HUMAN | [view interactions] | Low throughput | no | yes |
| CASP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASP7_HUMAN | [view interactions] | Low throughput | no | no |
| BIRC6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CCNA2_HUMAN | [view interactions] | Low throughput | no | no |
| CDC27_HUMAN | [view interactions] | Low throughput | no | yes |
| APC11_HUMAN | [view interactions] | Low throughput | no | yes |
| MCPH1_HUMAN | [view interactions] | Low throughput | no | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| AGO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ESRP1_HUMAN | [view interactions] | Low throughput | no | yes |
| STX17_HUMAN | [view interactions] | Low throughput | no | yes |
| SNP29_HUMAN | [view interactions] | Low throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | Low throughput | no | yes |
| UBA6_HUMAN | [view interactions] | Low throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MLP3C_HUMAN | [view interactions] | Low throughput | no | no |
| UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
| GBRAP_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GBRL1_HUMAN | [view interactions] | Low throughput | no | yes |
| CASP8_HUMAN | [view interactions] | Low throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CYBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSH6_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| IPO11_HUMAN | [view interactions] | High throughput | no | yes |
| CLPB_HUMAN | [view interactions] | High throughput | no | yes |
| TIM29_HUMAN | [view interactions] | High throughput | no | no |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| CALR3_HUMAN | [view interactions] | High throughput | no | no |
| CLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| ARL10_HUMAN | [view interactions] | High throughput | no | yes |
| ARL16_HUMAN | [view interactions] | High throughput | no | no |
| DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| PF21A_HUMAN | [view interactions] | High throughput | no | yes |
| RCOR1_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| VAV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| BIRC5_HUMAN | [view interactions] | High throughput | no | no |
| EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| L2GL2_HUMAN | [view interactions] | High throughput | no | yes |
| WDR48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF22_HUMAN | [view interactions] | High throughput | no | no |
| MYH13_HUMAN | [view interactions] | High throughput | no | no |
| ATS4_HUMAN | [view interactions] | High throughput | no | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| DCA12_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOS_HUMAN | [view interactions] | High throughput | no | no |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGRP_HUMAN | [view interactions] | High throughput | no | no |
| UGGG2_HUMAN | [view interactions] | High throughput | no | no |
| VEGFD_HUMAN | [view interactions] | High throughput | no | no |
| ANGL3_HUMAN | [view interactions] | High throughput | no | no |
| RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMA1_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| DYRK2_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD61_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASF2_HUMAN | [view interactions] | High throughput | no | yes |
| RPGR_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| SSH3_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TEX35_HUMAN | [view interactions] | High throughput | no | no |
| PRS45_HUMAN | [view interactions] | High throughput | no | no |
| RTBDN_HUMAN | [view interactions] | High throughput | no | no |
| CC020_HUMAN | [view interactions] | High throughput | no | no |
| WDR4_HUMAN | [view interactions] | High throughput | no | no |
| GSDME_HUMAN | [view interactions] | High throughput | no | yes |
| ABRX2_HUMAN | [view interactions] | High throughput | no | yes |
| CAH11_HUMAN | [view interactions] | High throughput | no | no |
| CHIA_HUMAN | [view interactions] | High throughput | no | yes |
| CLC11_HUMAN | [view interactions] | High throughput | no | no |
| TB22A_HUMAN | [view interactions] | High throughput | no | yes |
| CCNQ_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FERM2_HUMAN | [view interactions] | High throughput | no | yes |
| OSBL2_HUMAN | [view interactions] | High throughput | no | yes |
| HEY1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| RUN3A_HUMAN | [view interactions] | High throughput | no | yes |
| MF2L2_HUMAN | [view interactions] | High throughput | no | no |
| PLPL1_HUMAN | [view interactions] | High throughput | no | no |
| SOSB1_HUMAN | [view interactions] | High throughput | no | yes |
| CD79B_HUMAN | [view interactions] | High throughput | no | no |
| MCH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCL17_HUMAN | [view interactions] | High throughput | no | yes |
| TAFA3_HUMAN | [view interactions] | High throughput | no | no |
| TTLL5_HUMAN | [view interactions] | High throughput | no | yes |
| CAPSL_HUMAN | [view interactions] | High throughput | no | no |
| SPSB3_HUMAN | [view interactions] | High throughput | no | yes |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| ISK14_HUMAN | [view interactions] | High throughput | no | no |
| LDOC1_HUMAN | [view interactions] | High throughput | no | no |
| STRAA_HUMAN | [view interactions] | High throughput | no | yes |
| DEN5A_HUMAN | [view interactions] | High throughput | no | yes |
| TM266_HUMAN | [view interactions] | High throughput | no | no |
| CCL18_HUMAN | [view interactions] | High throughput | no | no |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PATE1_HUMAN | [view interactions] | High throughput | no | no |
| RAMP1_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABTB2_HUMAN | [view interactions] | High throughput | no | yes |
| TM135_HUMAN | [view interactions] | High throughput | no | yes |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| BFSP1_HUMAN | [view interactions] | High throughput | no | no |
| CXCL3_HUMAN | [view interactions] | High throughput | no | no |
| TOR2A_HUMAN | [view interactions] | High throughput | no | no |
| PP4P1_HUMAN | [view interactions] | High throughput | no | yes |
| IQCF2_HUMAN | [view interactions] | High throughput | no | no |
| PPR21_HUMAN | [view interactions] | High throughput | no | yes |
| INF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GROA_HUMAN | [view interactions] | High throughput | no | no |
| DIK1A_HUMAN | [view interactions] | High throughput | no | yes |
| LPIN3_HUMAN | [view interactions] | High throughput | no | yes |
| KLH33_HUMAN | [view interactions] | High throughput | no | yes |
| SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
| S22A9_HUMAN | [view interactions] | High throughput | no | no |
| CUED1_HUMAN | [view interactions] | High throughput | no | yes |
| CYTC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNPEP_HUMAN | [view interactions] | High throughput | no | yes |
| PRTN3_HUMAN | [view interactions] | High throughput | no | no |
| PTH_HUMAN | [view interactions] | High throughput | no | yes |
| ITLN2_HUMAN | [view interactions] | High throughput | no | no |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB2_HUMAN | [view interactions] | High throughput | no | no |
| EP15R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| BLTP1_HUMAN | [view interactions] | High throughput | no | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SON_HUMAN | [view interactions] | High throughput | no | yes |
| VP13B_HUMAN | [view interactions] | High throughput | no | no |
| MBD3_HUMAN | [view interactions] | High throughput | no | yes |