EXOC3_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC3_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 37.9310 | 4 | no |
| GO:0000166 | nucleotide binding | 31.0345 | 4 | no |
| GO:0017076 | purine nucleotide binding | 31.0345 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 31.0345 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.0345 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 25.8621 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 25.8621 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 25.8621 | 6 | no |
| GO:0003924 | GTPase activity | 22.4138 | 7 | no |
| GO:0005525 | GTP binding | 22.4138 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 22.4138 | 6 | no |
| GO:0032561 | guanyl ribonucleotide binding | 22.4138 | 5 | no |
| GO:0045296 | cadherin binding | 6.8966 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.1724 | 4 | no |
| GO:0008104 | protein localization | 53.4483 | 4 | yes |
| GO:0071702 | organic substance transport | 44.8276 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 43.1034 | 4 | yes |
| GO:0010646 | regulation of cell communication | 39.6552 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 37.9310 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 37.9310 | 4 | no |
| GO:0015031 | protein transport | 36.2069 | 4 | yes |
| GO:0006996 | organelle organization | 36.2069 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 34.4828 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 34.4828 | 4 | no |
| GO:0022607 | cellular component assembly | 32.7586 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.7586 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 31.0345 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.0345 | 4 | no |
| GO:0009966 | regulation of signal transduction | 31.0345 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 31.0345 | 4 | no |
| GO:0051049 | regulation of transport | 29.3103 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 29.3103 | 4 | no |
| GO:0061024 | membrane organization | 27.5862 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 27.5862 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.5862 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.5862 | 4 | no |
| GO:0046903 | secretion | 25.8621 | 4 | yes |
| GO:0009967 | positive regulation of signal transduction | 25.8621 | 5 | no |
| GO:0010468 | regulation of gene expression | 25.8621 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.8621 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.8621 | 5 | no |
| GO:0030030 | cell projection organization | 24.1379 | 4 | no |
| GO:0030334 | regulation of cell migration | 24.1379 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 24.1379 | 5 | no |
| GO:2000145 | regulation of cell motility | 24.1379 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 22.4138 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.4138 | 6 | no |
| GO:0060341 | regulation of cellular localization | 20.6897 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 20.6897 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 20.6897 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 20.6897 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.6897 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.6897 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.6897 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.6897 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 20.6897 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.6897 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.6897 | 6 | no |
| GO:0000281 | mitotic cytokinesis | 18.9655 | 4 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 18.9655 | 4 | yes |
| GO:0048278 | vesicle docking | 17.2414 | 4 | yes |
| GO:0090148 | membrane fission | 15.5172 | 5 | yes |
| GO:0099022 | vesicle tethering | 15.5172 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LAP4B_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | Low throughput | no | yes |
| CCND1_HUMAN | [view interactions] | Low throughput | no | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RALB_HUMAN | [view interactions] | Low throughput | no | no |
| RALA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRP19_HUMAN | [view interactions] | Low throughput | no | yes |
| KHDC4_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| YTDC1_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP11_HUMAN | [view interactions] | High throughput | no | yes |
| TRM2A_HUMAN | [view interactions] | High throughput | no | yes |
| CAN5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K6_HUMAN | [view interactions] | High throughput | no | yes |
| NCF4_HUMAN | [view interactions] | High throughput | no | no |
| SCMC3_HUMAN | [view interactions] | High throughput | no | yes |
| STAP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZER1_HUMAN | [view interactions] | High throughput | no | no |
| GTPBA_HUMAN | [view interactions] | High throughput | no | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| T2H2L_HUMAN | [view interactions] | High throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLH1_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MKNK2_HUMAN | [view interactions] | High throughput | no | yes |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKD2_HUMAN | [view interactions] | High throughput | no | yes |
| TRIPB_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD2_HUMAN | [view interactions] | High throughput | no | no |
| GCC2_HUMAN | [view interactions] | High throughput | no | yes |
| PIBF1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| MACD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| RA1L2_HUMAN | [view interactions] | High throughput | no | no |
| RET_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| BUB3_HUMAN | [view interactions] | High throughput | no | yes |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| PP12C_HUMAN | [view interactions] | High throughput | no | yes |
| GMCL1_HUMAN | [view interactions] | High throughput | no | yes |
| POC1B_HUMAN | [view interactions] | High throughput | no | no |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMED1_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRH_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| TRI32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TULP3_HUMAN | [view interactions] | High throughput | no | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| KIZ_HUMAN | [view interactions] | High throughput | no | no |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| CC136_HUMAN | [view interactions] | High throughput | no | yes |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC25_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| CML1_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA9_HUMAN | [view interactions] | High throughput | no | no |
| GLPA_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| KI2L4_HUMAN | [view interactions] | High throughput | no | no |
| MTLR_HUMAN | [view interactions] | High throughput | no | no |
| EDNRB_HUMAN | [view interactions] | High throughput | no | no |
| IL7RA_HUMAN | [view interactions] | High throughput | no | no |
| IQIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SCHI1_HUMAN | [view interactions] | High throughput | no | yes |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| V2R_HUMAN | [view interactions] | High throughput | no | no |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| KRT37_HUMAN | [view interactions] | High throughput | no | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| PTH2R_HUMAN | [view interactions] | High throughput | no | no |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VMAT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VPS52_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RABE2_HUMAN | [view interactions] | High throughput | no | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |