Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

EXC6B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in EXC6B_HUMAN
GO:0017076 purine nucleotide binding 28.5714 4 no
GO:0032555 purine ribonucleotide binding 28.5714 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.5714 4 no
GO:0031267 small GTPase binding 28.5714 5 no
GO:0051020 GTPase binding 28.5714 4 no
GO:0003924 GTPase activity 21.4286 7 no
GO:0005525 GTP binding 21.4286 5 no
GO:0016462 pyrophosphatase activity 21.4286 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 21.4286 4 no
GO:0017022 myosin binding 21.4286 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 21.4286 6 no
GO:0019001 guanyl nucleotide binding 21.4286 5 no
GO:0032561 guanyl ribonucleotide binding 21.4286 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in EXC6B_HUMAN
GO:0008104 protein localization 92.8571 4 yes
GO:0006887 exocytosis 85.7143 4 yes
GO:0016192 vesicle-mediated transport 85.7143 4 yes
GO:0046903 secretion 85.7143 4 yes
GO:0015031 protein transport 78.5714 4 yes
GO:0071702 organic substance transport 78.5714 4 yes
GO:0071705 nitrogen compound transport 78.5714 4 yes
GO:0098876 vesicle-mediated transport to the plasma membrane 64.2857 4 yes
GO:0006892 post-Golgi vesicle-mediated transport 57.1429 6 yes
GO:0006893 Golgi to plasma membrane transport 57.1429 5 yes
GO:0048193 Golgi vesicle transport 57.1429 5 yes
GO:0006996 organelle organization 57.1429 4 no
GO:0030030 cell projection organization 42.8571 4 no
GO:0031323 regulation of cellular metabolic process 42.8571 4 no
GO:0072657 protein localization to membrane 42.8571 4 no
GO:1990778 protein localization to cell periphery 42.8571 5 no
GO:0033365 protein localization to organelle 42.8571 5 no
GO:0051049 regulation of transport 42.8571 4 no
GO:0009894 regulation of catabolic process 35.7143 4 no
GO:0022607 cellular component assembly 35.7143 4 no
GO:0031329 regulation of cellular catabolic process 35.7143 5 no
GO:0120036 plasma membrane bounded cell projection organization 35.7143 5 no
GO:0048522 positive regulation of cellular process 35.7143 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 28.5714 6 no
GO:1903530 regulation of secretion by cell 28.5714 4 no
GO:0010506 regulation of autophagy 28.5714 6 no
GO:0016241 regulation of macroautophagy 28.5714 7 no
GO:0070925 organelle assembly 28.5714 5 no
GO:0007010 cytoskeleton organization 28.5714 5 no
GO:0022603 regulation of anatomical structure morphogenesis 28.5714 4 no
GO:0031344 regulation of cell projection organization 28.5714 5 no
GO:0051046 regulation of secretion 28.5714 5 no
GO:0051128 regulation of cellular component organization 28.5714 4 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0060627 regulation of vesicle-mediated transport 28.5714 4 no
GO:0030031 cell projection assembly 21.4286 5 no
GO:0044782 cilium organization 21.4286 5 no
GO:0060271 cilium assembly 21.4286 6 no
GO:0061512 protein localization to cilium 21.4286 6 no
GO:0120031 plasma membrane bounded cell projection assembly 21.4286 6 no
GO:1903441 protein localization to ciliary membrane 21.4286 5 no
GO:0016050 vesicle organization 21.4286 5 no
GO:0072659 protein localization to plasma membrane 21.4286 5 no
GO:0010975 regulation of neuron projection development 21.4286 7 no
GO:0031175 neuron projection development 21.4286 6 no
GO:0006886 intracellular protein transport 21.4286 4 yes
GO:0099022 vesicle tethering 21.4286 4 yes
GO:0017157 regulation of exocytosis 21.4286 5 no
GO:0031346 positive regulation of cell projection organization 21.4286 6 no
GO:0051094 positive regulation of developmental process 21.4286 4 no
GO:0072594 establishment of protein localization to organelle 21.4286 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
EXOC5_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC4_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC2_HUMAN [view entry] [view interactions] High throughput yes no
EXOC7_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC8_HUMAN [view entry] [view interactions] High throughput yes yes
EXOC1_HUMAN [view entry] [view interactions] High throughput yes yes
FAK2_HUMAN [view entry] [view interactions] High throughput yes yes
MTEF1_HUMAN [view interactions] High throughput no yes
EXOC3_HUMAN [view entry] [view interactions] High throughput yes no
EXOC6_HUMAN [view entry] [view interactions] High throughput yes yes
SHOT1_HUMAN [view interactions] High throughput no no
FTM_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
CAH14_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
SCN2B_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
IL1R2_HUMAN [view interactions] High throughput no no
EPHA1_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SMAD4_HUMAN [view interactions] High throughput no yes
GLPA_HUMAN [view interactions] High throughput no no
EFHD1_HUMAN [view interactions] High throughput no no
LURA1_HUMAN [view interactions] High throughput no yes
CC018_HUMAN [view interactions] High throughput no yes
EFNB1_HUMAN [view interactions] High throughput no yes
FCGRN_HUMAN [view interactions] High throughput no yes
KXDL1_HUMAN [view interactions] High throughput no yes
F234A_HUMAN [view interactions] High throughput no yes
IFT20_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB10_HUMAN [view entry] [view interactions] Computational yes yes
RALA_HUMAN [view entry] [view interactions] Computational yes yes