EXOC7_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC7_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 25.0000 | 4 | yes |
| GO:0043169 | cation binding | 22.2222 | 4 | no |
| GO:0046872 | metal ion binding | 22.2222 | 5 | no |
| GO:0035091 | phosphatidylinositol binding | 11.1111 | 4 | yes |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | 5.5556 | 5 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 5.5556 | 5 | yes |
| GO:1902936 | phosphatidylinositol bisphosphate binding | 5.5556 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC7_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.1111 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.7778 | 4 | no |
| GO:0008104 | protein localization | 47.2222 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 47.2222 | 4 | yes |
| GO:0006996 | organelle organization | 41.6667 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.6667 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 38.8889 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 38.8889 | 4 | no |
| GO:0071702 | organic substance transport | 38.8889 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 38.8889 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 36.1111 | 4 | no |
| GO:0022607 | cellular component assembly | 36.1111 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 36.1111 | 5 | no |
| GO:0023056 | positive regulation of signaling | 36.1111 | 4 | no |
| GO:0015031 | protein transport | 36.1111 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 36.1111 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.1111 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 30.5556 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.5556 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 30.5556 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 30.5556 | 4 | no |
| GO:0046903 | secretion | 30.5556 | 4 | yes |
| GO:0061024 | membrane organization | 30.5556 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.5556 | 5 | no |
| GO:0030030 | cell projection organization | 27.7778 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 27.7778 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 27.7778 | 4 | no |
| GO:0010468 | regulation of gene expression | 27.7778 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.7778 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 27.7778 | 5 | no |
| GO:0090148 | membrane fission | 27.7778 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.0000 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 25.0000 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0051049 | regulation of transport | 25.0000 | 4 | no |
| GO:0000281 | mitotic cytokinesis | 25.0000 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 25.0000 | 4 | yes |
| GO:0048278 | vesicle docking | 25.0000 | 4 | yes |
| GO:0061640 | cytoskeleton-dependent cytokinesis | 25.0000 | 4 | yes |
| GO:0099022 | vesicle tethering | 25.0000 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 22.2222 | 6 | no |
| GO:0006892 | post-Golgi vesicle-mediated transport | 22.2222 | 4 | no |
| GO:0006893 | Golgi to plasma membrane transport | 22.2222 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.2222 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.2222 | 6 | no |
| GO:0050806 | positive regulation of synaptic transmission | 22.2222 | 5 | no |
| GO:0016050 | vesicle organization | 22.2222 | 5 | no |
| GO:0010506 | regulation of autophagy | 16.6667 | 6 | yes |
| GO:0016241 | regulation of macroautophagy | 16.6667 | 7 | yes |
| GO:0031329 | regulation of cellular catabolic process | 16.6667 | 5 | yes |
| GO:0052372 | modulation by symbiont of entry into host | 5.5556 | 4 | yes |
| GO:2000535 | regulation of entry of bacterium into host cell | 5.5556 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BIG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LAP4B_HUMAN | [view interactions] | Low throughput | no | yes |
| PI42A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PRP19_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | Low throughput | no | no |
| ARC1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BBS1_HUMAN | [view interactions] | High throughput | no | no |
| BBS4_HUMAN | [view interactions] | High throughput | no | no |
| BBS2_HUMAN | [view interactions] | High throughput | no | no |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| IFT57_HUMAN | [view interactions] | High throughput | no | yes |
| SIGL1_HUMAN | [view interactions] | High throughput | no | no |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| POC1B_HUMAN | [view interactions] | High throughput | no | no |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| CAH14_HUMAN | [view interactions] | High throughput | no | yes |
| FCGRN_HUMAN | [view interactions] | High throughput | no | yes |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DSN1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| TSKS_HUMAN | [view interactions] | High throughput | no | no |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| SRCRL_HUMAN | [view interactions] | High throughput | no | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| MSGN1_HUMAN | [view interactions] | High throughput | no | no |
| SAPC2_HUMAN | [view interactions] | High throughput | no | no |
| YAE1_HUMAN | [view interactions] | High throughput | no | yes |
| CT55_HUMAN | [view interactions] | High throughput | no | no |
| FBX28_HUMAN | [view interactions] | High throughput | no | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| LDOC1_HUMAN | [view interactions] | High throughput | no | no |
| AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| RT4I1_HUMAN | [view interactions] | High throughput | no | yes |
| CC85B_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BBS7_HUMAN | [view interactions] | High throughput | no | no |
| OLIG2_HUMAN | [view interactions] | High throughput | no | no |
| PKNX1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| NRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| PNKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| ANGP4_HUMAN | [view interactions] | High throughput | no | no |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| GLPA_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| CC018_HUMAN | [view interactions] | High throughput | no | yes |
| ODAD1_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T4S5_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAMAC_HUMAN | [view interactions] | High throughput | no | yes |
| RIOX2_HUMAN | [view interactions] | High throughput | no | yes |
| RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |