EXOC7_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC7_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 28.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC7_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 64.0000 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 56.0000 | 4 | yes |
| GO:0006996 | organelle organization | 56.0000 | 4 | no |
| GO:0071702 | organic substance transport | 50.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | no |
| GO:0015031 | protein transport | 48.0000 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 48.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 46.0000 | 4 | no |
| GO:0046903 | secretion | 40.0000 | 4 | yes |
| GO:0051049 | regulation of transport | 40.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.0000 | 4 | yes |
| GO:0030030 | cell projection organization | 38.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.0000 | 4 | no |
| GO:0006887 | exocytosis | 36.0000 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 36.0000 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 36.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 32.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 32.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 32.0000 | 4 | no |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 32.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 30.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.0000 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 30.0000 | 4 | no |
| GO:0072657 | protein localization to membrane | 28.0000 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 28.0000 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 28.0000 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 26.0000 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 26.0000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 26.0000 | 5 | no |
| GO:0006892 | post-Golgi vesicle-mediated transport | 26.0000 | 6 | no |
| GO:0048193 | Golgi vesicle transport | 26.0000 | 5 | no |
| GO:0051046 | regulation of secretion | 26.0000 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 26.0000 | 4 | no |
| GO:0016050 | vesicle organization | 26.0000 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.0000 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 26.0000 | 5 | no |
| GO:0033365 | protein localization to organelle | 24.0000 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 24.0000 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 24.0000 | 5 | no |
| GO:0007010 | cytoskeleton organization | 24.0000 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.0000 | 6 | no |
| GO:1990778 | protein localization to cell periphery | 22.0000 | 5 | yes |
| GO:0032880 | regulation of protein localization | 22.0000 | 5 | no |
| GO:0071310 | cellular response to organic substance | 22.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 22.0000 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 22.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.0000 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.0000 | 6 | no |
| GO:0033043 | regulation of organelle organization | 22.0000 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.0000 | 4 | no |
| GO:0009894 | regulation of catabolic process | 18.0000 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 16.0000 | 5 | yes |
| GO:0010506 | regulation of autophagy | 14.0000 | 6 | yes |
| GO:0016241 | regulation of macroautophagy | 12.0000 | 7 | yes |
| GO:0061512 | protein localization to cilium | 10.0000 | 6 | yes |
| GO:1903441 | protein localization to ciliary membrane | 6.0000 | 5 | yes |
| GO:0052372 | modulation by symbiont of entry into host | 4.0000 | 4 | yes |
| GO:2000535 | regulation of entry of bacterium into host cell | 4.0000 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC7_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 4.0000 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PRP19_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | Low throughput | no | no |
| ARC1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BIG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LAP4B_HUMAN | [view interactions] | Low throughput | no | yes |
| PI42A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| RT4I1_HUMAN | [view interactions] | High throughput | no | yes |
| CC85B_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BBS7_HUMAN | [view interactions] | High throughput | no | no |
| EXOC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| PNKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| TBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| ANGP4_HUMAN | [view interactions] | High throughput | no | no |
| BTNL9_HUMAN | [view interactions] | High throughput | no | no |
| EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| GLPA_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10A6_HUMAN | [view interactions] | High throughput | no | yes |
| CC018_HUMAN | [view interactions] | High throughput | no | yes |
| ODAD1_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T4S5_HUMAN | [view interactions] | High throughput | no | no |
| TACD2_HUMAN | [view interactions] | High throughput | no | no |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAMAC_HUMAN | [view interactions] | High throughput | no | yes |
| RIOX2_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BBS1_HUMAN | [view interactions] | High throughput | no | no |
| BBS4_HUMAN | [view interactions] | High throughput | no | no |
| BBS2_HUMAN | [view interactions] | High throughput | no | no |
| IFT57_HUMAN | [view interactions] | High throughput | no | yes |
| SIGL1_HUMAN | [view interactions] | High throughput | no | no |
| EPHA1_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| POC1B_HUMAN | [view interactions] | High throughput | no | no |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| CAH14_HUMAN | [view interactions] | High throughput | no | yes |
| FCGRN_HUMAN | [view interactions] | High throughput | no | yes |
| SCN2B_HUMAN | [view interactions] | High throughput | no | no |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSN1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| TSKS_HUMAN | [view interactions] | High throughput | no | no |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| SRCRL_HUMAN | [view interactions] | High throughput | no | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| PKHF2_HUMAN | [view interactions] | High throughput | no | yes |
| MSGN1_HUMAN | [view interactions] | High throughput | no | no |
| SAPC2_HUMAN | [view interactions] | High throughput | no | no |
| YAE1_HUMAN | [view interactions] | High throughput | no | yes |
| CT55_HUMAN | [view interactions] | High throughput | no | no |
| FBX28_HUMAN | [view interactions] | High throughput | no | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| LDOC1_HUMAN | [view interactions] | High throughput | no | no |
| AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT2_HUMAN | [view interactions] | Computational | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CIP4_HUMAN | [view interactions] | Computational | no | no |
| TNAP2_HUMAN | [view interactions] | Computational | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RALA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RFIP3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB3I_HUMAN | [view interactions] | Computational | no | no |
| STXB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COG2_HUMAN | [view interactions] | Computational | no | no |
| C2CD5_HUMAN | [view interactions] | Computational | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLUT4_HUMAN | [view interactions] | Computational | no | no |
| STX4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| EX3L4_HUMAN | [view interactions] | Computational | no | no |
| VAMP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB8A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNP23_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MYO5A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |