EXOC4_HUMAN
Evidence for PS localization
Functions
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in EXOC4_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 28.3951 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.3951 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.1605 | 4 | no |
| GO:0019900 | kinase binding | 23.4568 | 4 | no |
| GO:0019901 | protein kinase binding | 20.9877 | 5 | no |
| GO:0051020 | GTPase binding | 13.5802 | 4 | yes |
| GO:0031267 | small GTPase binding | 11.1111 | 5 | yes |
| GO:0030165 | PDZ domain binding | 4.9383 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in EXOC4_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 62.9630 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 55.5556 | 4 | no |
| GO:0006996 | organelle organization | 50.6173 | 4 | yes |
| GO:0010646 | regulation of cell communication | 41.9753 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 41.9753 | 4 | yes |
| GO:0071702 | organic substance transport | 41.9753 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 41.9753 | 4 | no |
| GO:0071705 | nitrogen compound transport | 40.7407 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 39.5062 | 4 | no |
| GO:0015031 | protein transport | 39.5062 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 39.5062 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 38.2716 | 4 | no |
| GO:0022607 | cellular component assembly | 38.2716 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 37.0370 | 4 | no |
| GO:0051049 | regulation of transport | 35.8025 | 4 | no |
| GO:0009966 | regulation of signal transduction | 34.5679 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 34.5679 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 32.0988 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.6296 | 5 | no |
| GO:0007010 | cytoskeleton organization | 28.3951 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 27.1605 | 5 | no |
| GO:0030030 | cell projection organization | 27.1605 | 4 | yes |
| GO:0046903 | secretion | 27.1605 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.9259 | 5 | no |
| GO:0060341 | regulation of cellular localization | 25.9259 | 4 | no |
| GO:0010468 | regulation of gene expression | 25.9259 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 25.9259 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.9259 | 4 | no |
| GO:0072657 | protein localization to membrane | 25.9259 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.9259 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 24.6914 | 5 | no |
| GO:0032880 | regulation of protein localization | 23.4568 | 5 | no |
| GO:0071310 | cellular response to organic substance | 23.4568 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.4568 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.4568 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.2222 | 6 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 22.2222 | 4 | no |
| GO:0006887 | exocytosis | 22.2222 | 4 | yes |
| GO:0033365 | protein localization to organelle | 22.2222 | 5 | yes |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 22.2222 | 4 | yes |
| GO:1990778 | protein localization to cell periphery | 22.2222 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 20.9877 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.9877 | 5 | no |
| GO:0006892 | post-Golgi vesicle-mediated transport | 17.2840 | 6 | yes |
| GO:0048193 | Golgi vesicle transport | 17.2840 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 14.8148 | 4 | yes |
| GO:0006893 | Golgi to plasma membrane transport | 13.5802 | 5 | yes |
| GO:0030031 | cell projection assembly | 13.5802 | 5 | yes |
| GO:0031329 | regulation of cellular catabolic process | 13.5802 | 5 | yes |
| GO:0070925 | organelle assembly | 13.5802 | 5 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 13.5802 | 6 | yes |
| GO:0007268 | chemical synaptic transmission | 12.3457 | 6 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 12.3457 | 5 | yes |
| GO:0099537 | trans-synaptic signaling | 12.3457 | 4 | yes |
| GO:0010506 | regulation of autophagy | 11.1111 | 6 | yes |
| GO:0048278 | vesicle docking | 9.8765 | 4 | yes |
| GO:0016241 | regulation of macroautophagy | 7.4074 | 7 | yes |
| GO:0044782 | cilium organization | 7.4074 | 5 | yes |
| GO:0060271 | cilium assembly | 7.4074 | 6 | yes |
| GO:0061512 | protein localization to cilium | 7.4074 | 6 | yes |
| GO:1903441 | protein localization to ciliary membrane | 6.1728 | 5 | yes |
| GO:0099022 | vesicle tethering | 4.9383 | 4 | yes |
| GO:0001707 | mesoderm formation | 2.4691 | 4 | yes |
| GO:0048341 | paraxial mesoderm formation | 2.4691 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RALA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EX3L2_HUMAN | [view interactions] | Low throughput | no | no |
| TP53B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BIRC6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATG5_HUMAN | [view interactions] | Low throughput | no | no |
| JIP4_HUMAN | [view interactions] | Low throughput | no | yes |
| LAP4B_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KIBRA_HUMAN | [view interactions] | Low throughput | no | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PI42A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTM1_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| WASH1_HUMAN | [view interactions] | Low throughput | no | yes |
| PAXI_HUMAN | [view interactions] | Low throughput | no | yes |
| KPCI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| DRC5_HUMAN | [view interactions] | High throughput | no | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| CNTRB_HUMAN | [view interactions] | High throughput | no | yes |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| SPZ1_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| RALB_HUMAN | [view interactions] | High throughput | no | no |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| MBD3_HUMAN | [view interactions] | High throughput | no | yes |
| SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| ING1_HUMAN | [view interactions] | High throughput | no | yes |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SETB1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| LNX2_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR4_HUMAN | [view interactions] | High throughput | no | no |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS7_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS6_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS5_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS3_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRT86_HUMAN | [view interactions] | High throughput | no | no |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| SYCE3_HUMAN | [view interactions] | High throughput | no | no |
| IQIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SCHI1_HUMAN | [view interactions] | High throughput | no | yes |
| EX3L1_HUMAN | [view interactions] | High throughput | no | yes |
| KRT81_HUMAN | [view interactions] | High throughput | no | no |
| SIKE1_HUMAN | [view interactions] | High throughput | no | yes |
| KRT83_HUMAN | [view interactions] | High throughput | no | no |
| KT222_HUMAN | [view interactions] | High throughput | no | no |
| KRT38_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CML1_HUMAN | [view interactions] | High throughput | no | yes |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARL1_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRAS2_HUMAN | [view interactions] | High throughput | no | yes |
| YLAT2_HUMAN | [view interactions] | High throughput | no | no |
| PTAR1_HUMAN | [view interactions] | High throughput | no | yes |
| CHIO_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPXN_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STRP2_HUMAN | [view interactions] | High throughput | no | yes |
| STRN3_HUMAN | [view interactions] | High throughput | no | yes |
| STXB2_HUMAN | [view interactions] | High throughput | no | no |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| CEGT_HUMAN | [view interactions] | High throughput | no | yes |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACBD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CLIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| PEX14_HUMAN | [view interactions] | High throughput | no | yes |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED29_HUMAN | [view interactions] | High throughput | no | no |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| APJ_HUMAN | [view interactions] | High throughput | no | yes |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| IL1R2_HUMAN | [view interactions] | High throughput | no | no |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| GGA1_HUMAN | [view interactions] | High throughput | no | yes |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| IKBB_HUMAN | [view interactions] | High throughput | no | no |
| POC1B_HUMAN | [view interactions] | High throughput | no | no |
| EIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS51_HUMAN | [view interactions] | High throughput | no | yes |
| EXC6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RABE2_HUMAN | [view interactions] | High throughput | no | yes |
| HAUS8_HUMAN | [view interactions] | High throughput | no | yes |
| RAB13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TNAP2_HUMAN | [view interactions] | Computational | no | no |
| CIP4_HUMAN | [view interactions] | Computational | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLUT4_HUMAN | [view interactions] | Computational | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| C2CD5_HUMAN | [view interactions] | Computational | no | yes |
| AQP5_HUMAN | [view interactions] | Computational | no | no |
| RAB14_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| STXB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB3I_HUMAN | [view interactions] | Computational | no | no |
| AQP3_HUMAN | [view interactions] | Computational | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| EX3L4_HUMAN | [view interactions] | Computational | no | no |
| VAMP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AFAD_HUMAN | [view interactions] | Computational | no | yes |
| NECT2_HUMAN | [view interactions] | Computational | no | no |
| MYH9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| STX4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RHOQ_HUMAN | [view interactions] | Computational | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CTND1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAB8A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CTNA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SNP23_HUMAN | [view entry] [view interactions] | Computational | yes | no |