ATG5_HUMAN
Evidence for PS localization
Functions
(Microbial infection) May act as a proviral factor. In association with ATG12, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection (PubMed). Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for initiation of HCV replication, but not required once infection is established (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 122 | Glu | Asp | Spinocerebellarataxia,autosomalrecessive,25(SCAR25) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ATG5_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 36.1842 | 4 | no |
| GO:0000166 | nucleotide binding | 26.3158 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 25.6579 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.6579 | 4 | no |
| GO:0003723 | RNA binding | 25.6579 | 4 | no |
| GO:0017076 | purine nucleotide binding | 25.6579 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 22.3684 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.3684 | 5 | no |
| GO:0005524 | ATP binding | 22.3684 | 5 | no |
| GO:0016755 | aminoacyltransferase activity | 3.2895 | 4 | yes |
| GO:0061659 | ubiquitin-like protein ligase activity | 2.6316 | 4 | yes |
| GO:0019776 | Atg8-family ligase activity | 1.3158 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ATG5_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 47.3684 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 47.3684 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 46.0526 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 44.0789 | 4 | yes |
| GO:0022607 | cellular component assembly | 42.7632 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 42.7632 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 41.4474 | 4 | yes |
| GO:0006996 | organelle organization | 38.8158 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 36.8421 | 4 | no |
| GO:0008104 | protein localization | 36.1842 | 4 | no |
| GO:0010646 | regulation of cell communication | 34.2105 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 34.2105 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 33.5526 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 33.5526 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.8947 | 5 | yes |
| GO:0071702 | organic substance transport | 31.5789 | 4 | no |
| GO:0009966 | regulation of signal transduction | 30.9211 | 4 | no |
| GO:0043933 | protein-containing complex organization | 30.2632 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 29.6053 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.9474 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 28.9474 | 5 | no |
| GO:0051049 | regulation of transport | 27.6316 | 4 | yes |
| GO:0015031 | protein transport | 26.9737 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.3158 | 5 | no |
| GO:0010468 | regulation of gene expression | 25.6579 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 25.0000 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0060341 | regulation of cellular localization | 23.6842 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.0263 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 23.0263 | 5 | no |
| GO:0032880 | regulation of protein localization | 23.0263 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.3684 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 22.3684 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 22.3684 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 21.7105 | 4 | no |
| GO:0009894 | regulation of catabolic process | 21.7105 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 21.0526 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.0526 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.0526 | 5 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 20.3947 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 19.0789 | 4 | yes |
| GO:0043412 | macromolecule modification | 19.0789 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 19.0789 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 18.4211 | 6 | yes |
| GO:0036211 | protein modification process | 18.4211 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 18.4211 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 18.4211 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 17.7632 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 17.7632 | 4 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 16.4474 | 6 | yes |
| GO:0009890 | negative regulation of biosynthetic process | 16.4474 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 16.4474 | 6 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 15.7895 | 4 | yes |
| GO:0080134 | regulation of response to stress | 15.7895 | 4 | yes |
| GO:0051050 | positive regulation of transport | 15.1316 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 14.4737 | 4 | yes |
| GO:0051046 | regulation of secretion | 13.8158 | 5 | yes |
| GO:0030100 | regulation of endocytosis | 13.1579 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 13.1579 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 13.1579 | 6 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 12.5000 | 6 | yes |
| GO:0031329 | regulation of cellular catabolic process | 11.8421 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 11.8421 | 6 | yes |
| GO:0043069 | negative regulation of programmed cell death | 11.8421 | 5 | yes |
| GO:0070925 | organelle assembly | 11.8421 | 5 | yes |
| GO:0090304 | nucleic acid metabolic process | 11.8421 | 4 | yes |
| GO:0050776 | regulation of immune response | 11.1842 | 4 | yes |
| GO:0010506 | regulation of autophagy | 11.1842 | 6 | yes |
| GO:0010629 | negative regulation of gene expression | 11.1842 | 7 | yes |
| GO:0031347 | regulation of defense response | 10.5263 | 5 | yes |
| GO:0009059 | macromolecule biosynthetic process | 10.5263 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 9.8684 | 4 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 9.8684 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 9.8684 | 4 | yes |
| GO:0051051 | negative regulation of transport | 9.2105 | 4 | yes |
| GO:0001817 | regulation of cytokine production | 9.2105 | 4 | yes |
| GO:0007005 | mitochondrion organization | 9.2105 | 5 | yes |
| GO:0009057 | macromolecule catabolic process | 9.2105 | 4 | yes |
| GO:0031400 | negative regulation of protein modification process | 8.5526 | 7 | yes |
| GO:0016070 | RNA metabolic process | 8.5526 | 5 | yes |
| GO:0022411 | cellular component disassembly | 7.8947 | 4 | yes |
| GO:0034762 | regulation of transmembrane transport | 7.8947 | 4 | yes |
| GO:0051047 | positive regulation of secretion | 7.8947 | 5 | yes |
| GO:1901873 | regulation of post-translational protein modification | 7.8947 | 7 | yes |
| GO:1903320 | regulation of protein modification by small protein conjugation or removal | 7.8947 | 8 | yes |
| GO:0002831 | regulation of response to biotic stimulus | 7.8947 | 4 | yes |
| GO:0006915 | apoptotic process | 7.8947 | 4 | yes |
| GO:0016236 | macroautophagy | 7.2368 | 4 | yes |
| GO:0031396 | regulation of protein ubiquitination | 7.2368 | 9 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 7.2368 | 4 | yes |
| GO:0043687 | post-translational protein modification | 7.2368 | 5 | yes |
| GO:0062197 | cellular response to chemical stress | 7.2368 | 4 | yes |
| GO:0030163 | protein catabolic process | 6.5789 | 4 | yes |
| GO:0043269 | regulation of monoatomic ion transport | 6.5789 | 5 | yes |
| GO:0045088 | regulation of innate immune response | 6.5789 | 5 | yes |
| GO:0060491 | regulation of cell projection assembly | 6.5789 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 6.5789 | 6 | yes |
| GO:0007033 | vacuole organization | 6.5789 | 5 | yes |
| GO:0010959 | regulation of metal ion transport | 6.5789 | 6 | yes |
| GO:0016241 | regulation of macroautophagy | 5.9211 | 7 | yes |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 5.9211 | 5 | yes |
| GO:0046903 | secretion | 5.9211 | 4 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 5.9211 | 6 | yes |
| GO:1903008 | organelle disassembly | 5.9211 | 5 | yes |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 5.9211 | 6 | yes |
| GO:1905037 | autophagosome organization | 5.9211 | 6 | yes |
| GO:0000045 | autophagosome assembly | 5.9211 | 6 | yes |
| GO:0141187 | nucleic acid biosynthetic process | 5.2632 | 5 | yes |
| GO:1902115 | regulation of organelle assembly | 5.2632 | 5 | yes |
| GO:0009267 | cellular response to starvation | 5.2632 | 4 | yes |
| GO:0031397 | negative regulation of protein ubiquitination | 4.6053 | 10 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 4.6053 | 5 | yes |
| GO:0032446 | protein modification by small protein conjugation | 4.6053 | 7 | yes |
| GO:0051924 | regulation of calcium ion transport | 4.6053 | 7 | yes |
| GO:0071824 | protein-DNA complex organization | 4.6053 | 5 | yes |
| GO:1901874 | negative regulation of post-translational protein modification | 4.6053 | 8 | yes |
| GO:1903169 | regulation of calcium ion transmembrane transport | 4.6053 | 7 | yes |
| GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 4.6053 | 9 | yes |
| GO:0000422 | autophagy of mitochondrion | 4.6053 | 4 | yes |
| GO:0002683 | negative regulation of immune system process | 4.6053 | 4 | yes |
| GO:0002697 | regulation of immune effector process | 4.6053 | 4 | yes |
| GO:0006325 | chromatin organization | 4.6053 | 6 | yes |
| GO:0010038 | response to metal ion | 4.6053 | 4 | yes |
| GO:0016567 | protein ubiquitination | 3.9474 | 8 | yes |
| GO:0031348 | negative regulation of defense response | 3.9474 | 5 | yes |
| GO:0032774 | RNA biosynthetic process | 3.9474 | 5 | yes |
| GO:0045806 | negative regulation of endocytosis | 3.9474 | 5 | yes |
| GO:0003018 | vascular process in circulatory system | 3.9474 | 4 | yes |
| GO:0043562 | cellular response to nitrogen levels | 3.2895 | 4 | yes |
| GO:0048524 | positive regulation of viral process | 3.2895 | 4 | yes |
| GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 3.2895 | 5 | yes |
| GO:0051282 | regulation of sequestering of calcium ion | 3.2895 | 4 | yes |
| GO:0055001 | muscle cell development | 3.2895 | 4 | yes |
| GO:1902017 | regulation of cilium assembly | 3.2895 | 6 | yes |
| GO:0001818 | negative regulation of cytokine production | 3.2895 | 5 | yes |
| GO:0006995 | cellular response to nitrogen starvation | 3.2895 | 5 | yes |
| GO:0010660 | regulation of muscle cell apoptotic process | 3.2895 | 6 | yes |
| GO:0010662 | regulation of striated muscle cell apoptotic process | 3.2895 | 7 | yes |
| GO:0010665 | regulation of cardiac muscle cell apoptotic process | 3.2895 | 8 | yes |
| GO:0032479 | regulation of type I interferon production | 2.6316 | 5 | yes |
| GO:0043244 | regulation of protein-containing complex disassembly | 2.6316 | 5 | yes |
| GO:0045824 | negative regulation of innate immune response | 2.6316 | 6 | yes |
| GO:0050764 | regulation of phagocytosis | 2.6316 | 6 | yes |
| GO:0050777 | negative regulation of immune response | 2.6316 | 5 | yes |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 2.6316 | 5 | yes |
| GO:0002832 | negative regulation of response to biotic stimulus | 2.6316 | 5 | yes |
| GO:0010039 | response to iron ion | 2.6316 | 5 | yes |
| GO:0010040 | response to iron(II) ion | 2.6316 | 6 | yes |
| GO:0010656 | negative regulation of muscle cell apoptotic process | 2.6316 | 7 | yes |
| GO:0010664 | negative regulation of striated muscle cell apoptotic process | 2.6316 | 8 | yes |
| GO:0010667 | negative regulation of cardiac muscle cell apoptotic process | 2.6316 | 9 | yes |
| GO:0032480 | negative regulation of type I interferon production | 1.9737 | 6 | yes |
| GO:0035150 | regulation of tube size | 1.9737 | 4 | yes |
| GO:0035296 | regulation of tube diameter | 1.9737 | 5 | yes |
| GO:0039689 | negative stranded viral RNA replication | 1.9737 | 4 | yes |
| GO:0050688 | regulation of defense response to virus | 1.9737 | 5 | yes |
| GO:0050765 | negative regulation of phagocytosis | 1.9737 | 6 | yes |
| GO:0055006 | cardiac cell development | 1.9737 | 4 | yes |
| GO:0055013 | cardiac muscle cell development | 1.9737 | 5 | yes |
| GO:0055015 | ventricular cardiac muscle cell development | 1.9737 | 6 | yes |
| GO:0061684 | chaperone-mediated autophagy | 1.9737 | 4 | yes |
| GO:0097746 | blood vessel diameter maintenance | 1.9737 | 5 | yes |
| GO:2000378 | negative regulation of reactive oxygen species metabolic process | 1.9737 | 6 | yes |
| GO:0002700 | regulation of production of molecular mediator of immune response | 1.9737 | 5 | yes |
| GO:0002718 | regulation of cytokine production involved in immune response | 1.9737 | 5 | yes |
| GO:0007589 | body fluid secretion | 1.9737 | 4 | yes |
| GO:0035973 | aggrephagy | 1.3158 | 5 | yes |
| GO:0042311 | vasodilation | 1.3158 | 6 | yes |
| GO:0044804 | nucleophagy | 1.3158 | 5 | yes |
| GO:0045060 | negative thymic T cell selection | 1.3158 | 4 | yes |
| GO:0050687 | negative regulation of defense response to virus | 1.3158 | 6 | yes |
| GO:0060047 | heart contraction | 1.3158 | 5 | yes |
| GO:0070255 | regulation of mucus secretion | 1.3158 | 4 | yes |
| GO:0070257 | positive regulation of mucus secretion | 1.3158 | 5 | yes |
| GO:0071500 | cellular response to nitrosative stress | 1.3158 | 4 | yes |
| GO:1901096 | regulation of autophagosome maturation | 1.3158 | 6 | yes |
| GO:1902617 | response to fluoride | 1.3158 | 4 | yes |
| GO:1904092 | regulation of autophagic cell death | 1.3158 | 5 | yes |
| GO:1904093 | negative regulation of autophagic cell death | 1.3158 | 6 | yes |
| GO:1904971 | regulation of viral translation | 1.3158 | 4 | yes |
| GO:1904973 | positive regulation of viral translation | 1.3158 | 5 | yes |
| GO:0003015 | heart process | 1.3158 | 4 | yes |
| GO:0010657 | muscle cell apoptotic process | 1.3158 | 5 | yes |
| GO:0010658 | striated muscle cell apoptotic process | 1.3158 | 6 | yes |
| GO:0010659 | cardiac muscle cell apoptotic process | 1.3158 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ATG10_HUMAN | [view interactions] | Low throughput | no | yes |
| ATG12_HUMAN | [view interactions] | Low throughput | no | yes |
| WDFY3_HUMAN | [view interactions] | Low throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TCPR1_HUMAN | [view interactions] | Low throughput | no | no |
| A16L2_HUMAN | [view interactions] | Low throughput | no | yes |
| ATG5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ATG3_HUMAN | [view interactions] | Low throughput | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RIGI_HUMAN | [view interactions] | Low throughput | no | yes |
| MAVS_HUMAN | [view interactions] | Low throughput | no | yes |
| SIR1_HUMAN | [view interactions] | Low throughput | no | yes |
| FADD_HUMAN | [view interactions] | Low throughput | no | yes |
| RIPK1_HUMAN | [view interactions] | Low throughput | no | yes |
| CASP8_HUMAN | [view interactions] | Low throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | Low throughput | no | no |
| PSA7_HUMAN | [view interactions] | Low throughput | no | yes |
| NLRP6_HUMAN | [view interactions] | Low throughput | no | no |
| PSB5_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PINK1_HUMAN | [view interactions] | Low throughput | no | yes |
| UBP13_HUMAN | [view interactions] | Low throughput | no | yes |
| INGR1_HUMAN | [view interactions] | Low throughput | no | no |
| JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RALB_HUMAN | [view interactions] | Low throughput | no | no |
| TNR1A_HUMAN | [view interactions] | Low throughput | no | yes |
| IRG1_HUMAN | [view interactions] | Low throughput | no | no |
| CACO2_HUMAN | [view interactions] | Low throughput | no | yes |
| CAN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| TAB3_HUMAN | [view interactions] | Low throughput | no | yes |
| IRGM_HUMAN | [view interactions] | Low throughput | no | no |
| RB33B_HUMAN | [view interactions] | Low throughput | no | no |
| CAV1_HUMAN | [view interactions] | Low throughput | no | no |
| WIPI2_HUMAN | [view interactions] | Low throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL10_HUMAN | [view interactions] | Low throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| BSN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | Low throughput | no | yes |
| PSD10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| DAPK2_HUMAN | [view interactions] | Low throughput | no | no |
| RACK1_HUMAN | [view interactions] | Low throughput | no | yes |
| BIRC5_HUMAN | [view interactions] | Low throughput | no | no |
| ASPP2_HUMAN | [view interactions] | Low throughput | no | yes |
| IASPP_HUMAN | [view interactions] | Low throughput | no | yes |
| MYD88_HUMAN | [view interactions] | Low throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | Low throughput | no | yes |
| RB33A_HUMAN | [view interactions] | Low throughput | no | no |
| TNR6_HUMAN | [view interactions] | Low throughput | no | no |
| PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
| SKP2_HUMAN | [view interactions] | Low throughput | no | yes |
| HMGB2_HUMAN | [view interactions] | High throughput | no | yes |
| BRI3B_HUMAN | [view interactions] | High throughput | no | yes |
| MAP6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GET4_HUMAN | [view interactions] | High throughput | no | yes |
| NUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| SELM_HUMAN | [view interactions] | High throughput | no | yes |
| CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYADM_HUMAN | [view interactions] | High throughput | no | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AEBP1_HUMAN | [view interactions] | High throughput | no | yes |
| INP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNN1_HUMAN | [view interactions] | High throughput | no | no |
| SIL1_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GEMI5_HUMAN | [view interactions] | High throughput | no | yes |
| CAH5B_HUMAN | [view interactions] | High throughput | no | yes |
| CDD_HUMAN | [view interactions] | High throughput | no | no |
| SPB8_HUMAN | [view interactions] | High throughput | no | no |
| GSLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WNK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FA76B_HUMAN | [view interactions] | High throughput | no | no |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHF6_HUMAN | [view interactions] | High throughput | no | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KKCC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYAR_HUMAN | [view interactions] | High throughput | no | no |
| UCK2_HUMAN | [view interactions] | High throughput | no | no |
| APBB2_HUMAN | [view interactions] | High throughput | no | yes |
| C2D1B_HUMAN | [view interactions] | High throughput | no | yes |
| GAPD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF4A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COBL1_HUMAN | [view interactions] | High throughput | no | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAS3_HUMAN | [view interactions] | High throughput | no | yes |
| HEAT6_HUMAN | [view interactions] | High throughput | no | no |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STEEP_HUMAN | [view interactions] | High throughput | no | yes |
| HAGHL_HUMAN | [view interactions] | High throughput | no | no |
| TM10C_HUMAN | [view interactions] | High throughput | no | yes |
| GNPAT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| PREB_HUMAN | [view interactions] | High throughput | no | yes |
| FHOD1_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| HEXA_HUMAN | [view interactions] | High throughput | no | yes |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CARF_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| NJMU_HUMAN | [view interactions] | High throughput | no | yes |
| CCD12_HUMAN | [view interactions] | High throughput | no | yes |
| EDC4_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | High throughput | no | yes |
| PLAP_HUMAN | [view interactions] | High throughput | no | yes |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FUND2_HUMAN | [view interactions] | High throughput | no | yes |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| PDS5B_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3C_HUMAN | [view interactions] | High throughput | no | no |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| PCD18_HUMAN | [view interactions] | High throughput | no | yes |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KV105_HUMAN | [view interactions] | High throughput | no | no |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| EDAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| TPC6B_HUMAN | [view interactions] | High throughput | no | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SACS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIH1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| RBGP1_HUMAN | [view interactions] | High throughput | no | yes |
| RA51C_HUMAN | [view interactions] | High throughput | no | no |
| RT17_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| SPD2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ULK1_HUMAN | [view interactions] | High throughput | no | no |
| PKHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| TMX1_HUMAN | [view interactions] | High throughput | no | no |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P5CR2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LUC7L_HUMAN | [view interactions] | High throughput | no | yes |
| THIC_HUMAN | [view interactions] | High throughput | no | yes |
| SPART_HUMAN | [view interactions] | High throughput | no | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGO1_HUMAN | [view interactions] | High throughput | no | yes |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBBP4_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| AATM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMB1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRL1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTMR9_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| SIR4_HUMAN | [view interactions] | High throughput | no | yes |
| PSA2_HUMAN | [view interactions] | High throughput | no | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS50_HUMAN | [view interactions] | High throughput | no | yes |
| GSTM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RT27_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| MB12A_HUMAN | [view interactions] | High throughput | no | yes |
| CDN2A_HUMAN | [view interactions] | High throughput | no | yes |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| RCC2_HUMAN | [view interactions] | High throughput | no | no |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPD2B_HUMAN | [view interactions] | High throughput | no | no |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP14_HUMAN | [view interactions] | High throughput | no | no |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FABP5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| UFSP1_HUMAN | [view interactions] | High throughput | no | yes |
| GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAUS5_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACADV_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| UBR1_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC_HUMAN | [view interactions] | High throughput | no | yes |
| CARL1_HUMAN | [view interactions] | High throughput | no | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX17_HUMAN | [view interactions] | High throughput | no | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD1_HUMAN | [view interactions] | High throughput | no | no |
| ORN_HUMAN | [view interactions] | High throughput | no | no |
| PROF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCD12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FER_HUMAN | [view interactions] | High throughput | no | yes |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GXLT1_HUMAN | [view interactions] | High throughput | no | no |
| DHB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSN_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| RHPN2_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TEKT4_HUMAN | [view interactions] | High throughput | no | no |
| GRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| K1328_HUMAN | [view interactions] | High throughput | no | yes |
| ATP23_HUMAN | [view interactions] | High throughput | no | yes |
| INCA1_HUMAN | [view interactions] | High throughput | no | no |
| PSB11_HUMAN | [view interactions] | High throughput | no | no |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PK3C3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| PLAK2_HUMAN | [view interactions] | High throughput | no | no |
| TIAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| ATG2B_HUMAN | [view interactions] | High throughput | no | no |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FILA_HUMAN | [view interactions] | High throughput | no | no |
| GBP1_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAA_HUMAN | [view interactions] | High throughput | no | no |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIT5_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN213_HUMAN | [view interactions] | High throughput | no | yes |
| RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAMH1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| CXB2_HUMAN | [view interactions] | High throughput | no | yes |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXB1_HUMAN | [view interactions] | High throughput | no | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP13C_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| SYCE1_HUMAN | [view interactions] | High throughput | no | no |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRT37_HUMAN | [view interactions] | High throughput | no | no |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| KRT38_HUMAN | [view interactions] | High throughput | no | no |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| KAZRN_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| NR1D1_HUMAN | [view interactions] | High throughput | no | yes |
| DYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PGDH_HUMAN | [view interactions] | High throughput | no | no |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
| SNX9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPRI_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAS2_HUMAN | [view interactions] | High throughput | no | no |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| DNMBP_HUMAN | [view interactions] | High throughput | no | no |
| I5P2_HUMAN | [view interactions] | High throughput | no | yes |
| PACN3_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEN1A_HUMAN | [view interactions] | High throughput | no | no |
| SP16H_HUMAN | [view interactions] | High throughput | no | yes |
| AP1G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDC1_HUMAN | [view interactions] | High throughput | no | no |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACADS_HUMAN | [view interactions] | High throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MRCKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CATZ_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REPS1_HUMAN | [view interactions] | High throughput | no | yes |
| DAB2_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAP28_HUMAN | [view interactions] | High throughput | no | yes |
| LTN1_HUMAN | [view interactions] | High throughput | no | no |
| TYW3_HUMAN | [view interactions] | High throughput | no | yes |
| ARMC8_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| YJ005_HUMAN | [view interactions] | High throughput | no | no |
| WDR7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E2AK4_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP41_HUMAN | [view interactions] | High throughput | no | yes |
| TOP2A_HUMAN | [view interactions] | High throughput | no | no |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS45_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAVR1_HUMAN | [view interactions] | High throughput | no | no |
| TTC28_HUMAN | [view interactions] | High throughput | no | no |