SNAA_HUMAN
Evidence for PS localization
Functions
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNAA_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 32.1429 | 4 | no |
| GO:0019905 | syntaxin binding | 28.5714 | 4 | yes |
| GO:0019901 | protein kinase binding | 28.5714 | 5 | no |
| GO:0017076 | purine nucleotide binding | 23.2143 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 23.2143 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.2143 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNAA_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 66.0714 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 55.3571 | 4 | no |
| GO:0015031 | protein transport | 53.5714 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 53.5714 | 4 | yes |
| GO:0071702 | organic substance transport | 53.5714 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 53.5714 | 4 | yes |
| GO:0006996 | organelle organization | 51.7857 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 48.2143 | 4 | yes |
| GO:0010646 | regulation of cell communication | 48.2143 | 4 | no |
| GO:0022607 | cellular component assembly | 46.4286 | 4 | yes |
| GO:0051049 | regulation of transport | 46.4286 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 44.6429 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.6429 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.6429 | 4 | no |
| GO:0061024 | membrane organization | 42.8571 | 4 | yes |
| GO:0006886 | intracellular protein transport | 39.2857 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 39.2857 | 4 | no |
| GO:0009966 | regulation of signal transduction | 37.5000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.5000 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 37.5000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | no |
| GO:0080090 | regulation of primary metabolic process | 37.5000 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 35.7143 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 35.7143 | 4 | no |
| GO:0016050 | vesicle organization | 33.9286 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.9286 | 4 | no |
| GO:0043933 | protein-containing complex organization | 32.1429 | 4 | yes |
| GO:0061025 | membrane fusion | 32.1429 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 32.1429 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 32.1429 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 30.3571 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 30.3571 | 5 | no |
| GO:0032880 | regulation of protein localization | 28.5714 | 5 | no |
| GO:0060341 | regulation of cellular localization | 28.5714 | 4 | no |
| GO:0051046 | regulation of secretion | 28.5714 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 28.5714 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.5714 | 5 | no |
| GO:0031399 | regulation of protein modification process | 28.5714 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 28.5714 | 7 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.5714 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.5714 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 26.7857 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 26.7857 | 5 | no |
| GO:0046903 | secretion | 26.7857 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 26.7857 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 26.7857 | 4 | no |
| GO:0010941 | regulation of cell death | 26.7857 | 4 | no |
| GO:0051050 | positive regulation of transport | 26.7857 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0006887 | exocytosis | 25.0000 | 4 | no |
| GO:0006906 | vesicle fusion | 25.0000 | 6 | no |
| GO:0031344 | regulation of cell projection organization | 25.0000 | 5 | no |
| GO:0048284 | organelle fusion | 25.0000 | 5 | no |
| GO:0090174 | organelle membrane fusion | 25.0000 | 6 | no |
| GO:0043549 | regulation of kinase activity | 25.0000 | 5 | no |
| GO:0051338 | regulation of transferase activity | 25.0000 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.0000 | 7 | no |
| GO:0048193 | Golgi vesicle transport | 23.2143 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 23.2143 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.2143 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.2143 | 6 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 23.2143 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 23.2143 | 7 | no |
| GO:0017157 | regulation of exocytosis | 23.2143 | 5 | no |
| GO:0009894 | regulation of catabolic process | 21.4286 | 4 | no |
| GO:0048278 | vesicle docking | 21.4286 | 4 | no |
| GO:0010468 | regulation of gene expression | 21.4286 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.4286 | 4 | no |
| GO:0030030 | cell projection organization | 21.4286 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 21.4286 | 8 | no |
| GO:0031401 | positive regulation of protein modification process | 21.4286 | 7 | no |
| GO:0043269 | regulation of ion transport | 21.4286 | 5 | no |
| GO:0045859 | regulation of protein kinase activity | 21.4286 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 21.4286 | 5 | no |
| GO:0072657 | protein localization to membrane | 21.4286 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 21.4286 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 21.4286 | 5 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 19.6429 | 5 | yes |
| GO:0007268 | chemical synaptic transmission | 12.5000 | 6 | yes |
| GO:0010807 | regulation of synaptic vesicle priming | 12.5000 | 6 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 12.5000 | 5 | yes |
| GO:0099537 | trans-synaptic signaling | 12.5000 | 4 | yes |
| GO:0006891 | intra-Golgi vesicle-mediated transport | 10.7143 | 6 | yes |
| GO:0022411 | cellular component disassembly | 10.7143 | 4 | yes |
| GO:0032984 | protein-containing complex disassembly | 10.7143 | 5 | yes |
| GO:0007420 | brain development | 7.1429 | 4 | yes |
| GO:0035494 | SNARE complex disassembly | 7.1429 | 6 | yes |
| GO:0035249 | synaptic transmission, glutamatergic | 5.3571 | 7 | yes |
| GO:0030182 | neuron differentiation | 3.5714 | 4 | yes |
| GO:0045176 | apical protein localization | 3.5714 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SNAA_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 5.3571 | 3 | no |
| DOID:0050700 | cardiomyopathy | 3.5714 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.5714 | 5 | no |
| DOID:114 | heart disease | 3.5714 | 3 | no |
| DOID:2843 | long QT syndrome | 3.5714 | 6 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 3.5714 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 3.5714 | 6 | no |
| DOID:440 | neuromuscular disease | 3.5714 | 5 | no |
| DOID:574 | peripheral nervous system disease | 3.5714 | 3 | no |
| DOID:870 | neuropathy | 3.5714 | 4 | no |
| DOID:1826 | epilepsy | 3.5714 | 5 | no |
| DOID:936 | brain disease | 3.5714 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SNAA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NSF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX12_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX8_HUMAN | [view interactions] | Low throughput | no | yes |
| STX5_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP7_HUMAN | [view interactions] | Low throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNP25_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BCL2_HUMAN | [view interactions] | Low throughput | no | no |
| VAMP8_HUMAN | [view interactions] | Low throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RINT1_HUMAN | [view interactions] | High throughput | no | yes |
| SNAG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| ZW10_HUMAN | [view interactions] | High throughput | no | yes |
| NBAS_HUMAN | [view interactions] | High throughput | no | yes |
| STX18_HUMAN | [view interactions] | High throughput | no | yes |
| USE1_HUMAN | [view interactions] | High throughput | no | yes |
| BET1L_HUMAN | [view interactions] | High throughput | no | yes |
| VPS45_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VTI1A_HUMAN | [view interactions] | High throughput | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCFD2_HUMAN | [view interactions] | High throughput | no | yes |
| MAEA_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| SEC20_HUMAN | [view interactions] | High throughput | no | yes |
| TOP2B_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP4_HUMAN | [view interactions] | High throughput | no | yes |
| STX10_HUMAN | [view interactions] | High throughput | no | yes |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX16_HUMAN | [view interactions] | High throughput | no | yes |
| GOSR2_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| CNDD3_HUMAN | [view interactions] | High throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| ZNT4_HUMAN | [view interactions] | High throughput | no | no |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| STXB6_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| GOSR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KPRB_HUMAN | [view interactions] | High throughput | no | yes |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| NIPA3_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| WDR81_HUMAN | [view interactions] | High throughput | no | no |
| ASPH_HUMAN | [view interactions] | High throughput | no | yes |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| PLCA_HUMAN | [view interactions] | High throughput | no | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| PHF11_HUMAN | [view interactions] | High throughput | no | no |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| SERC2_HUMAN | [view interactions] | High throughput | no | yes |
| T185A_HUMAN | [view interactions] | High throughput | no | no |
| STXB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR91_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNAB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC5B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMDC1_HUMAN | [view interactions] | High throughput | no | no |
| ODR4_HUMAN | [view interactions] | High throughput | no | yes |
| STXB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBSK_HUMAN | [view interactions] | High throughput | no | yes |
| B4GT5_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| CS025_HUMAN | [view interactions] | High throughput | no | no |
| LIME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| CYS1_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| GORS2_HUMAN | [view interactions] | High throughput | no | yes |
| RT09_HUMAN | [view interactions] | High throughput | no | yes |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| RREB1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3B_HUMAN | [view interactions] | High throughput | no | yes |
| PTTG_HUMAN | [view interactions] | High throughput | no | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCAM2_HUMAN | [view interactions] | High throughput | no | no |
| STX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| YIPF5_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX40_HUMAN | [view interactions] | High throughput | no | yes |
| THUM3_HUMAN | [view interactions] | High throughput | no | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| DHX29_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| TRM6_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAMP1_HUMAN | [view interactions] | High throughput | no | no |
| OTULL_HUMAN | [view interactions] | High throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CPLX1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TXND5_HUMAN | [view interactions] | Computational | no | yes |
| SC22A_HUMAN | [view interactions] | Computational | no | no |
| STXB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARL1_HUMAN | [view interactions] | Computational | no | yes |
| BL1S3_HUMAN | [view interactions] | Computational | no | no |
| STX1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SC22C_HUMAN | [view interactions] | Computational | no | no |
| BL1S4_HUMAN | [view interactions] | Computational | no | yes |
| STX17_HUMAN | [view interactions] | Computational | no | yes |
| BL1S6_HUMAN | [view interactions] | Computational | no | yes |
| STX2_HUMAN | [view interactions] | Computational | no | no |