Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

IDHP_HUMAN

Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. [View more on UniProt]

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in IDHP_HUMAN
GO:0043169 cation binding 35.9375 4 yes
GO:0046872 metal ion binding 34.3750 5 yes
GO:0000166 nucleotide binding 26.5625 4 yes
GO:0017076 purine nucleotide binding 25.0000 5 yes
GO:0043168 anion binding 25.0000 4 no
GO:0030554 adenyl nucleotide binding 20.3125 6 yes
GO:0003723 RNA binding 20.3125 4 no
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 12.5000 4 yes
GO:0000287 magnesium ion binding 10.9375 6 yes
GO:0051287 NAD binding 10.9375 7 yes
GO:0004448 isocitrate dehydrogenase [NAD(P)+] activity 7.8125 5 yes
GO:0004450 isocitrate dehydrogenase (NADP+) activity 3.1250 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in IDHP_HUMAN
GO:0048523 negative regulation of cellular process 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0031323 regulation of cellular metabolic process 48.4375 4 no
GO:0048522 positive regulation of cellular process 48.4375 4 no
GO:0009889 regulation of biosynthetic process 45.3125 4 no
GO:0080090 regulation of primary metabolic process 45.3125 4 no
GO:0031326 regulation of cellular biosynthetic process 43.7500 5 no
GO:0010556 regulation of macromolecule biosynthetic process 42.1875 5 no
GO:0010468 regulation of gene expression 40.6250 6 no
GO:0010646 regulation of cell communication 39.0625 4 no
GO:0009893 positive regulation of metabolic process 39.0625 4 no
GO:0051246 regulation of protein metabolic process 34.3750 5 no
GO:0009966 regulation of signal transduction 32.8125 4 no
GO:0006996 organelle organization 32.8125 4 no
GO:0010604 positive regulation of macromolecule metabolic process 32.8125 5 no
GO:0031325 positive regulation of cellular metabolic process 32.8125 5 no
GO:0010648 negative regulation of cell communication 31.2500 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 31.2500 5 no
GO:0023057 negative regulation of signaling 31.2500 4 no
GO:0051128 regulation of cellular component organization 31.2500 4 no
GO:0008104 protein localization 31.2500 4 no
GO:0022607 cellular component assembly 31.2500 4 no
GO:0019752 carboxylic acid metabolic process 29.6875 5 yes
GO:0043436 oxoacid metabolic process 29.6875 4 yes
GO:0051252 regulation of RNA metabolic process 28.1250 5 no
GO:0009892 negative regulation of metabolic process 28.1250 4 no
GO:0031324 negative regulation of cellular metabolic process 28.1250 5 no
GO:0042981 regulation of apoptotic process 28.1250 5 no
GO:0043067 regulation of programmed cell death 28.1250 4 no
GO:0006355 regulation of DNA-templated transcription 26.5625 7 no
GO:0009968 negative regulation of signal transduction 26.5625 5 no
GO:0048585 negative regulation of response to stimulus 26.5625 4 no
GO:0051049 regulation of transport 26.5625 4 no
GO:2001141 regulation of RNA biosynthetic process 26.5625 6 no
GO:0009891 positive regulation of biosynthetic process 26.5625 5 no
GO:0071702 organic substance transport 26.5625 4 no
GO:0071705 nitrogen compound transport 25.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 23.4375 5 no
GO:1902531 regulation of intracellular signal transduction 23.4375 5 no
GO:0031328 positive regulation of cellular biosynthetic process 23.4375 6 no
GO:0031399 regulation of protein modification process 23.4375 6 no
GO:0009890 negative regulation of biosynthetic process 21.8750 5 no
GO:0019220 regulation of phosphate metabolic process 21.8750 6 no
GO:0051174 regulation of phosphorus metabolic process 21.8750 5 no
GO:0006796 phosphate-containing compound metabolic process 21.8750 4 yes
GO:0007010 cytoskeleton organization 21.8750 5 no
GO:0043933 protein-containing complex organization 21.8750 4 no
GO:0051247 positive regulation of protein metabolic process 21.8750 6 no
GO:0032880 regulation of protein localization 20.3125 5 no
GO:0060341 regulation of cellular localization 20.3125 4 no
GO:0009894 regulation of catabolic process 20.3125 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.3125 6 no
GO:0043066 negative regulation of apoptotic process 20.3125 6 no
GO:0043069 negative regulation of programmed cell death 20.3125 5 no
GO:0032787 monocarboxylic acid metabolic process 18.7500 6 yes
GO:0006753 nucleoside phosphate metabolic process 17.1875 4 yes
GO:0009117 nucleotide metabolic process 17.1875 5 yes
GO:0072521 purine-containing compound metabolic process 17.1875 4 yes
GO:0006163 purine nucleotide metabolic process 15.6250 5 yes
GO:0019362 pyridine nucleotide metabolic process 10.9375 5 yes
GO:0046496 nicotinamide nucleotide metabolic process 10.9375 6 yes
GO:0072350 tricarboxylic acid metabolic process 10.9375 6 yes
GO:0072524 pyridine-containing compound metabolic process 10.9375 4 yes
GO:1902652 secondary alcohol metabolic process 10.9375 4 yes
GO:0006102 isocitrate metabolic process 9.3750 5 yes
GO:0043648 dicarboxylic acid metabolic process 7.8125 6 yes
GO:0006739 NADP metabolic process 4.6875 6 yes
GO:0046487 glyoxylate metabolic process 4.6875 4 yes
GO:0006097 glyoxylate cycle 3.1250 4 yes
GO:0006103 2-oxoglutarate metabolic process 3.1250 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
B2MG_HUMAN [view interactions] Low throughput no yes
HLAB_HUMAN [view interactions] Low throughput no yes
IDHP_HUMAN [view entry] [view interactions] Low throughput yes yes
CDC20_HUMAN [view interactions] Low throughput no no
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
SIR3_HUMAN [view interactions] Low throughput no yes
SIR5_HUMAN [view interactions] Low throughput no yes
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
CDK1_HUMAN [view interactions] Low throughput no no
PLK1_HUMAN [view interactions] Low throughput no yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
ACPM_HUMAN [view interactions] High throughput no yes
PGM1_HUMAN [view interactions] High throughput no no
PRDX6_HUMAN [view entry] [view interactions] High throughput yes yes
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
ACADM_HUMAN [view interactions] High throughput no yes
ADHX_HUMAN [view interactions] High throughput no yes
TNC18_HUMAN [view interactions] High throughput no yes
TRM61_HUMAN [view interactions] High throughput no no
FUBP2_HUMAN [view interactions] High throughput no yes
GNA1_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
ATX1_HUMAN [view interactions] High throughput no yes
SYAM_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
CLPP_HUMAN [view interactions] High throughput no yes
CAVN3_HUMAN [view interactions] High throughput no no
ERBIN_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A1_HUMAN [view entry] [view interactions] High throughput yes no
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
PYGL_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
HDAC1_HUMAN [view interactions] High throughput no no
SIR4_HUMAN [view interactions] High throughput no yes
MD2L1_HUMAN [view interactions] High throughput no no
KBTB7_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
MAS_HUMAN [view interactions] High throughput no no
S15A1_HUMAN [view interactions] High throughput no no
S39A9_HUMAN [view interactions] High throughput no yes
KCMF1_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
TAGL_HUMAN [view interactions] High throughput no no
E2F1_HUMAN [view interactions] High throughput no yes
TMIG1_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
COQ2_HUMAN [view interactions] High throughput no yes
SOAT1_HUMAN [view interactions] High throughput no no
CEBPD_HUMAN [view interactions] High throughput no no
IRF2_HUMAN [view interactions] High throughput no yes
SNAA_HUMAN [view entry] [view interactions] High throughput yes yes
SIM26_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
AAKB1_HUMAN [view interactions] High throughput no yes
CAV3_HUMAN [view interactions] High throughput no no
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
HDAC5_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
CP135_HUMAN [view interactions] High throughput no no
FAKD3_HUMAN [view interactions] High throughput no yes
KDM4C_HUMAN [view interactions] High throughput no no
KDM4D_HUMAN [view interactions] High throughput no yes
IF2P_HUMAN [view interactions] High throughput no yes
ANXA5_HUMAN [view entry] [view interactions] High throughput yes no
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
PDIA3_HUMAN [view entry] [view interactions] High throughput yes yes
ZN207_HUMAN [view interactions] High throughput no yes
RU2B_HUMAN [view interactions] High throughput no yes
RM12_HUMAN [view interactions] High throughput no yes
PA2G4_HUMAN [view interactions] High throughput no yes
UBE2N_HUMAN [view entry] [view interactions] High throughput yes yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
SND1_HUMAN [view entry] [view interactions] High throughput yes yes
CRNN_HUMAN [view interactions] High throughput no no
SUMO3_HUMAN [view entry] [view interactions] High throughput yes yes
CDK2_HUMAN [view interactions] High throughput no yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
GLMP_HUMAN [view interactions] High throughput no no
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
SNAI1_HUMAN [view interactions] High throughput no yes
TGFR2_HUMAN [view interactions] High throughput no no
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
NFIX_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
ERP44_HUMAN [view interactions] High throughput no yes
SMHD1_HUMAN [view interactions] High throughput no yes
SF3A3_HUMAN [view interactions] High throughput no yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
RIF1_HUMAN [view interactions] High throughput no yes
SF3A1_HUMAN [view interactions] High throughput no yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
ACTN4_HUMAN [view entry] [view interactions] High throughput yes yes
RO52_HUMAN [view interactions] High throughput no yes
P5CS_HUMAN [view interactions] High throughput no yes
CNBP_HUMAN [view interactions] High throughput no no
RNF5_HUMAN [view interactions] High throughput no yes
RN103_HUMAN [view interactions] High throughput no no
RN170_HUMAN [view interactions] High throughput no yes
RN185_HUMAN [view interactions] High throughput no no
RNFT1_HUMAN [view interactions] High throughput no no
TRI13_HUMAN [view interactions] High throughput no no
ZNRF4_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
WDR5_HUMAN [view interactions] High throughput no no
INSRR_HUMAN [view interactions] High throughput no no
CD80_HUMAN [view interactions] High throughput no no
GLPA_HUMAN [view interactions] High throughput no no
HXC5_HUMAN [view interactions] High throughput no no
OR2A4_HUMAN [view interactions] High throughput no no
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
NRSN1_HUMAN [view interactions] High throughput no yes
OSGEP_HUMAN [view interactions] High throughput no yes
NGN3_HUMAN [view interactions] High throughput no no
PLCA_HUMAN [view interactions] High throughput no yes
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
RM42_HUMAN [view interactions] High throughput no yes
TECTB_HUMAN [view interactions] High throughput no no
SSUH2_HUMAN [view interactions] High throughput no no
TIDC1_HUMAN [view interactions] High throughput no yes
SERB1_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
CCR1_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
SARAF_HUMAN [view interactions] High throughput no no
CR021_HUMAN [view interactions] High throughput no no
SYT6_HUMAN [view entry] [view interactions] High throughput yes no
ANLN_HUMAN [view interactions] High throughput no yes
WIF1_HUMAN [view entry] [view interactions] High throughput yes no
GPR45_HUMAN [view interactions] High throughput no no
KIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
MBNL1_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
WIPI1_HUMAN [view interactions] High throughput no yes
RBCC1_HUMAN [view interactions] High throughput no no
CLU_HUMAN [view interactions] High throughput no yes
BAG1_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
MYCN_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
PARPT_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
FND3A_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
CL16A_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
MUS81_HUMAN [view interactions] High throughput no no
FBX7_HUMAN [view interactions] High throughput no yes
IDHC_HUMAN [view interactions] High throughput no no
G6PD_HUMAN [view entry] [view interactions] High throughput yes no
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3B_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3G_HUMAN [view entry] [view interactions] High throughput yes yes
GAL3A_HUMAN [view interactions] High throughput no yes
GAL3B_HUMAN [view interactions] High throughput no no
TPP1_HUMAN [view entry] [view interactions] High throughput yes yes
THTR_HUMAN [view interactions] High throughput no yes
KPYM_HUMAN [view interactions] High throughput no yes
FABPH_HUMAN [view entry] [view interactions] High throughput yes no
LYPL1_HUMAN [view interactions] High throughput no yes
DEST_HUMAN [view entry] [view interactions] High throughput yes yes
GLRX5_HUMAN [view interactions] High throughput no yes
CATB_HUMAN [view interactions] High throughput no yes
THIM_HUMAN [view interactions] High throughput no yes
AL4A1_HUMAN [view entry] [view interactions] High throughput yes yes
MPPA_HUMAN [view interactions] High throughput no yes
ICAM1_HUMAN [view interactions] High throughput no no
PTRD1_HUMAN [view interactions] High throughput no yes
AMPL_HUMAN [view entry] [view interactions] High throughput yes no
ISOC2_HUMAN [view interactions] High throughput no yes
INHBA_HUMAN [view interactions] High throughput no no
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
SODM_HUMAN [view entry] [view interactions] High throughput yes no
THIL_HUMAN [view entry] [view interactions] High throughput yes yes
CLIC4_HUMAN [view interactions] High throughput no no
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
SCP2_HUMAN [view interactions] High throughput no no
FRDA_HUMAN [view interactions] High throughput no yes
HCDH_HUMAN [view entry] [view interactions] High throughput yes yes
LEG3_HUMAN [view interactions] High throughput no yes
FAHD1_HUMAN [view interactions] High throughput no yes
COPD_HUMAN [view entry] [view interactions] High throughput yes yes
CLIC1_HUMAN [view interactions] High throughput no no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
ADX_HUMAN [view interactions] High throughput no no
GCSH_HUMAN [view interactions] High throughput no yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
COA7_HUMAN [view interactions] High throughput no yes
GRHPR_HUMAN [view entry] [view interactions] High throughput yes no
HINT2_HUMAN [view interactions] High throughput no yes
NENF_HUMAN [view interactions] High throughput no yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
PDP1_HUMAN [view interactions] High throughput no yes