G6PI_HUMAN
Evidence for PS localization
Functions
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (PubMed). Besides its role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility (PubMed). Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons (PubMed, PubMed). It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (PubMed, PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in G6PI_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 30.3571 | 4 | no |
| GO:0046872 | metal ion binding | 30.3571 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.5714 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.5714 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 26.7857 | 5 | no |
| GO:0003723 | RNA binding | 26.7857 | 4 | no |
| GO:0005524 | ATP binding | 25.0000 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.0000 | 5 | no |
| GO:0016301 | kinase activity | 21.4286 | 4 | no |
| GO:0019900 | kinase binding | 21.4286 | 4 | no |
| GO:0031625 | ubiquitin protein ligase binding | 19.6429 | 5 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 19.6429 | 4 | yes |
| GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses | 5.3571 | 4 | yes |
| GO:0004347 | glucose-6-phosphate isomerase activity | 3.5714 | 5 | yes |
| GO:0005125 | cytokine activity | 3.5714 | 5 | yes |
| GO:0008083 | growth factor activity | 3.5714 | 5 | yes |
| GO:0048018 | receptor ligand activity | 3.5714 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in G6PI_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 51.7857 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 42.8571 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 42.8571 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 42.8571 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 41.0714 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 37.5000 | 4 | yes |
| GO:0010468 | regulation of gene expression | 37.5000 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.7143 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 35.7143 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.9286 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.1429 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.3571 | 4 | yes |
| GO:0010941 | regulation of cell death | 30.3571 | 4 | yes |
| GO:0016310 | phosphorylation | 30.3571 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.3571 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.5714 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 28.5714 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 28.5714 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 28.5714 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 28.5714 | 4 | yes |
| GO:0043412 | macromolecule modification | 28.5714 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 28.5714 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.5714 | 5 | no |
| GO:0036211 | protein modification process | 26.7857 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 25.0000 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 25.0000 | 5 | no |
| GO:0006996 | organelle organization | 25.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 23.2143 | 6 | yes |
| GO:0048584 | positive regulation of response to stimulus | 23.2143 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.2143 | 6 | no |
| GO:0023056 | positive regulation of signaling | 21.4286 | 4 | no |
| GO:0080134 | regulation of response to stress | 21.4286 | 4 | no |
| GO:0080135 | regulation of cellular response to stress | 21.4286 | 4 | no |
| GO:0006753 | nucleoside phosphate metabolic process | 19.6429 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 19.6429 | 5 | yes |
| GO:0030162 | regulation of proteolysis | 19.6429 | 6 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 19.6429 | 6 | yes |
| GO:0043066 | negative regulation of apoptotic process | 19.6429 | 7 | yes |
| GO:0043069 | negative regulation of programmed cell death | 19.6429 | 6 | yes |
| GO:0060548 | negative regulation of cell death | 19.6429 | 5 | yes |
| GO:0010243 | response to organonitrogen compound | 17.8571 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 17.8571 | 4 | yes |
| GO:0050890 | cognition | 17.8571 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 17.8571 | 6 | yes |
| GO:0006165 | nucleoside diphosphate phosphorylation | 16.0714 | 6 | yes |
| GO:0009132 | nucleoside diphosphate metabolic process | 16.0714 | 5 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 16.0714 | 5 | yes |
| GO:0009185 | ribonucleoside diphosphate metabolic process | 16.0714 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 16.0714 | 5 | yes |
| GO:0046939 | nucleotide phosphorylation | 16.0714 | 6 | yes |
| GO:0051336 | regulation of hydrolase activity | 16.0714 | 4 | yes |
| GO:0006090 | pyruvate metabolic process | 14.2857 | 7 | yes |
| GO:0006096 | glycolytic process | 14.2857 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 14.2857 | 5 | yes |
| GO:0006757 | ATP generation from ADP | 14.2857 | 4 | yes |
| GO:0009135 | purine nucleoside diphosphate metabolic process | 14.2857 | 6 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 14.2857 | 6 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 14.2857 | 6 | yes |
| GO:0009179 | purine ribonucleoside diphosphate metabolic process | 14.2857 | 7 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 14.2857 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 14.2857 | 7 | yes |
| GO:0016052 | carbohydrate catabolic process | 14.2857 | 4 | yes |
| GO:0046031 | ADP metabolic process | 14.2857 | 7 | yes |
| GO:0046034 | ATP metabolic process | 14.2857 | 7 | yes |
| GO:0072521 | purine-containing compound metabolic process | 14.2857 | 4 | yes |
| GO:1901214 | regulation of neuron death | 14.2857 | 5 | yes |
| GO:0019318 | hexose metabolic process | 12.5000 | 4 | yes |
| GO:0043086 | negative regulation of catalytic activity | 12.5000 | 4 | yes |
| GO:0006006 | glucose metabolic process | 10.7143 | 5 | yes |
| GO:0010038 | response to metal ion | 10.7143 | 4 | yes |
| GO:0014070 | response to organic cyclic compound | 10.7143 | 4 | yes |
| GO:0043523 | regulation of neuron apoptotic process | 10.7143 | 6 | yes |
| GO:1901215 | negative regulation of neuron death | 10.7143 | 6 | yes |
| GO:0002684 | positive regulation of immune system process | 8.9286 | 4 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 8.9286 | 4 | yes |
| GO:0030334 | regulation of cell migration | 8.9286 | 5 | yes |
| GO:0033993 | response to lipid | 8.9286 | 4 | yes |
| GO:0043524 | negative regulation of neuron apoptotic process | 8.9286 | 7 | yes |
| GO:0046364 | monosaccharide biosynthetic process | 8.9286 | 4 | yes |
| GO:0048878 | chemical homeostasis | 8.9286 | 4 | yes |
| GO:0051346 | negative regulation of hydrolase activity | 8.9286 | 5 | yes |
| GO:0052547 | regulation of peptidase activity | 8.9286 | 5 | yes |
| GO:0052548 | regulation of endopeptidase activity | 8.9286 | 6 | yes |
| GO:2000145 | regulation of cell motility | 8.9286 | 4 | yes |
| GO:0006094 | gluconeogenesis | 7.1429 | 6 | yes |
| GO:0019319 | hexose biosynthetic process | 7.1429 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 7.1429 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 7.1429 | 4 | yes |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 7.1429 | 8 | yes |
| GO:0045861 | negative regulation of proteolysis | 7.1429 | 7 | yes |
| GO:0048872 | homeostasis of number of cells | 7.1429 | 4 | yes |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 7.1429 | 7 | yes |
| GO:2000147 | positive regulation of cell motility | 7.1429 | 5 | yes |
| GO:0002697 | regulation of immune effector process | 5.3571 | 4 | yes |
| GO:0002699 | positive regulation of immune effector process | 5.3571 | 5 | yes |
| GO:0002700 | regulation of production of molecular mediator of immune response | 5.3571 | 5 | yes |
| GO:0002702 | positive regulation of production of molecular mediator of immune response | 5.3571 | 6 | yes |
| GO:0007599 | hemostasis | 5.3571 | 4 | yes |
| GO:0010594 | regulation of endothelial cell migration | 5.3571 | 5 | yes |
| GO:0010595 | positive regulation of endothelial cell migration | 5.3571 | 6 | yes |
| GO:0010632 | regulation of epithelial cell migration | 5.3571 | 4 | yes |
| GO:0010634 | positive regulation of epithelial cell migration | 5.3571 | 5 | yes |
| GO:0014072 | response to isoquinoline alkaloid | 5.3571 | 5 | yes |
| GO:0032355 | response to estradiol | 5.3571 | 4 | yes |
| GO:0043278 | response to morphine | 5.3571 | 6 | yes |
| GO:0043279 | response to alkaloid | 5.3571 | 5 | yes |
| GO:0048545 | response to steroid hormone | 5.3571 | 4 | yes |
| GO:0051156 | glucose 6-phosphate metabolic process | 5.3571 | 4 | yes |
| GO:1901654 | response to ketone | 5.3571 | 4 | yes |
| GO:0001701 | in utero embryonic development | 3.5714 | 6 | yes |
| GO:0001707 | mesoderm formation | 3.5714 | 4 | yes |
| GO:0002637 | regulation of immunoglobulin production | 3.5714 | 6 | yes |
| GO:0002639 | positive regulation of immunoglobulin production | 3.5714 | 7 | yes |
| GO:0009792 | embryo development ending in birth or egg hatching | 3.5714 | 4 | yes |
| GO:0010466 | negative regulation of peptidase activity | 3.5714 | 6 | yes |
| GO:0010951 | negative regulation of endopeptidase activity | 3.5714 | 7 | yes |
| GO:0032570 | response to progesterone | 3.5714 | 5 | yes |
| GO:0033500 | carbohydrate homeostasis | 3.5714 | 5 | yes |
| GO:0033574 | response to testosterone | 3.5714 | 5 | yes |
| GO:0035994 | response to muscle stretch | 3.5714 | 4 | yes |
| GO:0042593 | glucose homeostasis | 3.5714 | 6 | yes |
| GO:0043009 | chordate embryonic development | 3.5714 | 5 | yes |
| GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.5714 | 8 | yes |
| GO:0046686 | response to cadmium ion | 3.5714 | 5 | yes |
| GO:2000117 | negative regulation of cysteine-type endopeptidase activity | 3.5714 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in G6PI_HUMAN |
|---|---|---|---|---|
| DOID:1289 | neurodegenerative disease | 3.5714 | 4 | no |
| DOID:331 | central nervous system disease | 3.5714 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| AMFR_HUMAN | [view interactions] | Low throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAR14_HUMAN | [view interactions] | Low throughput | no | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| TIE2_HUMAN | [view interactions] | High throughput | no | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK068_HUMAN | [view interactions] | High throughput | no | yes |
| SPICE_HUMAN | [view interactions] | High throughput | no | yes |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| IF2P_HUMAN | [view interactions] | High throughput | no | yes |
| HPRT_HUMAN | [view interactions] | High throughput | no | yes |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| CRNN_HUMAN | [view interactions] | High throughput | no | no |
| SIAS_HUMAN | [view interactions] | High throughput | no | yes |
| SND1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPYR_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RU2B_HUMAN | [view interactions] | High throughput | no | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPNE3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN207_HUMAN | [view interactions] | High throughput | no | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASB15_HUMAN | [view interactions] | High throughput | no | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PPME1_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| BRAF_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EYA2_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TISD_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| BRD3_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR3_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEM2_HUMAN | [view interactions] | High throughput | no | no |
| NDUB1_HUMAN | [view interactions] | High throughput | no | yes |
| PK3CG_HUMAN | [view interactions] | High throughput | no | yes |
| PTK6_HUMAN | [view interactions] | High throughput | no | yes |
| LTC4S_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYK2_HUMAN | [view interactions] | High throughput | no | no |
| PTPRZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNLI1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM256_HUMAN | [view interactions] | High throughput | no | no |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDC6I_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL4A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCXR_HUMAN | [view interactions] | High throughput | no | no |
| FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GABT_HUMAN | [view interactions] | High throughput | no | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESTD_HUMAN | [view interactions] | High throughput | no | yes |
| AATM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LACB2_HUMAN | [view interactions] | High throughput | no | yes |
| PGM1_HUMAN | [view interactions] | High throughput | no | no |
| PGM5_HUMAN | [view interactions] | High throughput | no | no |
| PRDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| DHSO_HUMAN | [view interactions] | High throughput | no | no |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEF1_HUMAN | [view interactions] | High throughput | no | no |
| ADA_HUMAN | [view interactions] | High throughput | no | no |
| CLIC1_HUMAN | [view interactions] | High throughput | no | no |
| ADPRS_HUMAN | [view interactions] | High throughput | no | yes |
| COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADX_HUMAN | [view interactions] | High throughput | no | no |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| GCSH_HUMAN | [view interactions] | High throughput | no | yes |
| GLOD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACPM_HUMAN | [view interactions] | High throughput | no | yes |
| 6PGL_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PFKAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAM41_HUMAN | [view interactions] | High throughput | no | no |
| ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
| SPRY4_HUMAN | [view interactions] | High throughput | no | yes |
| SOST_HUMAN | [view interactions] | High throughput | no | no |
| PPM1D_HUMAN | [view interactions] | High throughput | no | no |
| DUS7_HUMAN | [view interactions] | High throughput | no | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |