Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ANXA5_HUMAN

GO
G2C
SynGO

This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ANXA5_HUMAN
GO:0043169 cation binding 35.8974 4 yes
GO:0046872 metal ion binding 35.8974 5 yes
GO:0043168 anion binding 35.8974 4 no
GO:0003723 RNA binding 30.7692 4 no
GO:0000166 nucleotide binding 29.4872 4 no
GO:0017076 purine nucleotide binding 28.2051 5 no
GO:0032555 purine ribonucleotide binding 26.9231 4 no
GO:0035639 purine ribonucleoside triphosphate binding 25.6410 4 no
GO:0030554 adenyl nucleotide binding 24.3590 6 no
GO:0032559 adenyl ribonucleotide binding 23.0769 5 no
GO:0019900 kinase binding 23.0769 4 no
GO:0005524 ATP binding 21.7949 5 no
GO:0019901 protein kinase binding 20.5128 5 no
GO:0005509 calcium ion binding 19.2308 6 yes
GO:0004859 phospholipase inhibitor activity 5.1282 5 yes
GO:0005544 calcium-dependent phospholipid binding 5.1282 4 yes
GO:0055102 lipase inhibitor activity 5.1282 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ANXA5_HUMAN
GO:0048523 negative regulation of cellular process 56.4103 4 yes
GO:0031323 regulation of cellular metabolic process 55.1282 4 no
GO:0048522 positive regulation of cellular process 55.1282 4 no
GO:0060255 regulation of macromolecule metabolic process 55.1282 4 no
GO:0080090 regulation of primary metabolic process 52.5641 4 no
GO:0009889 regulation of biosynthetic process 46.1538 4 no
GO:0009893 positive regulation of metabolic process 46.1538 4 no
GO:0010468 regulation of gene expression 44.8718 6 no
GO:0010556 regulation of macromolecule biosynthetic process 44.8718 5 no
GO:0031326 regulation of cellular biosynthetic process 44.8718 5 no
GO:0010604 positive regulation of macromolecule metabolic process 43.5897 5 no
GO:0010646 regulation of cell communication 41.0256 4 no
GO:0031325 positive regulation of cellular metabolic process 41.0256 5 no
GO:0051246 regulation of protein metabolic process 41.0256 5 no
GO:0009966 regulation of signal transduction 37.1795 4 no
GO:0009892 negative regulation of metabolic process 35.8974 4 no
GO:0051128 regulation of cellular component organization 34.6154 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0048584 positive regulation of response to stimulus 33.3333 4 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0031399 regulation of protein modification process 32.0513 6 no
GO:0051247 positive regulation of protein metabolic process 30.7692 6 no
GO:0051049 regulation of transport 30.7692 4 no
GO:0042981 regulation of apoptotic process 29.4872 5 yes
GO:0043067 regulation of programmed cell death 29.4872 4 yes
GO:0009891 positive regulation of biosynthetic process 29.4872 5 no
GO:0019220 regulation of phosphate metabolic process 29.4872 6 no
GO:0051174 regulation of phosphorus metabolic process 29.4872 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 28.2051 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.2051 5 no
GO:0031328 positive regulation of cellular biosynthetic process 28.2051 6 no
GO:0006796 phosphate-containing compound metabolic process 26.9231 4 no
GO:0006996 organelle organization 26.9231 4 no
GO:0023056 positive regulation of signaling 26.9231 4 no
GO:0009967 positive regulation of signal transduction 25.6410 5 no
GO:0010647 positive regulation of cell communication 25.6410 5 no
GO:0022607 cellular component assembly 25.6410 4 no
GO:0042325 regulation of phosphorylation 25.6410 7 no
GO:0051252 regulation of RNA metabolic process 25.6410 5 no
GO:0009890 negative regulation of biosynthetic process 25.6410 5 no
GO:0001932 regulation of protein phosphorylation 24.3590 7 no
GO:0006355 regulation of DNA-templated transcription 24.3590 7 no
GO:0008104 protein localization 24.3590 4 no
GO:0031401 positive regulation of protein modification process 24.3590 7 no
GO:2001141 regulation of RNA biosynthetic process 24.3590 6 no
GO:0010558 negative regulation of macromolecule biosynthetic process 24.3590 6 no
GO:0031327 negative regulation of cellular biosynthetic process 24.3590 6 no
GO:0036211 protein modification process 23.0769 4 no
GO:0043412 macromolecule modification 23.0769 4 no
GO:0051130 positive regulation of cellular component organization 23.0769 5 no
GO:0010562 positive regulation of phosphorus metabolic process 21.7949 6 no
GO:0045937 positive regulation of phosphate metabolic process 21.7949 7 no
GO:0043066 negative regulation of apoptotic process 20.5128 6 yes
GO:0043069 negative regulation of programmed cell death 20.5128 5 yes
GO:0042327 positive regulation of phosphorylation 20.5128 8 no
GO:0071702 organic substance transport 20.5128 4 no
GO:0071705 nitrogen compound transport 20.5128 4 no
GO:1902533 positive regulation of intracellular signal transduction 20.5128 6 no
GO:0009894 regulation of catabolic process 20.5128 4 no
GO:0033043 regulation of organelle organization 20.5128 5 no
GO:0051240 positive regulation of multicellular organismal process 20.5128 4 no
GO:0051050 positive regulation of transport 20.5128 4 no
GO:0051241 negative regulation of multicellular organismal process 12.8205 4 yes
GO:0007599 hemostasis 3.8462 4 yes
GO:0050818 regulation of coagulation 3.8462 4 yes
GO:0050819 negative regulation of coagulation 3.8462 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ITSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
KCMA1_HUMAN [view entry] [view interactions] Low throughput yes no
VGFR2_HUMAN [view interactions] Low throughput no no
ITB5_HUMAN [view interactions] Low throughput no yes
TRI59_HUMAN [view interactions] Low throughput no no
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
CO2A1_HUMAN [view interactions] Low throughput no no
COAA1_HUMAN [view interactions] Low throughput no no
ANXA1_HUMAN [view entry] [view interactions] Low throughput yes no
ANXA5_HUMAN [view entry] [view interactions] Low throughput yes no
ATRX_HUMAN [view entry] [view interactions] Low throughput yes yes
DNMT1_HUMAN [view interactions] Low throughput no no
IF2P_HUMAN [view interactions] Low throughput no yes
KPCD2_HUMAN [view interactions] High throughput no yes
LMTK3_HUMAN [view entry] [view interactions] High throughput yes yes
BMI1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
GSC2_HUMAN [view interactions] High throughput no no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
OPTN_HUMAN [view interactions] High throughput no yes
FDFT_HUMAN [view interactions] High throughput no yes
IF4G1_HUMAN [view entry] [view interactions] High throughput yes yes
SPT4H_HUMAN [view interactions] High throughput no no
PDS5A_HUMAN [view interactions] High throughput no yes
CK068_HUMAN [view interactions] High throughput no yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
RPR1B_HUMAN [view interactions] High throughput no yes
TIF1A_HUMAN [view interactions] High throughput no yes
TERF1_HUMAN [view interactions] High throughput no no
TERF2_HUMAN [view interactions] High throughput no yes
TE2IP_HUMAN [view interactions] High throughput no yes
LEG2_HUMAN [view interactions] High throughput no no
UBB_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
RS27A_HUMAN [view entry] [view interactions] High throughput yes yes
RL40_HUMAN [view entry] [view interactions] High throughput yes yes
CPNE3_HUMAN [view interactions] High throughput no yes
HPRT_HUMAN [view interactions] High throughput no yes
IDHP_HUMAN [view entry] [view interactions] High throughput yes yes
RU2B_HUMAN [view interactions] High throughput no yes
UBE2N_HUMAN [view entry] [view interactions] High throughput yes yes
IPYR_HUMAN [view interactions] High throughput no yes
SIAS_HUMAN [view interactions] High throughput no yes
PA2G4_HUMAN [view interactions] High throughput no yes
PYGL_HUMAN [view interactions] High throughput no yes
G6PI_HUMAN [view entry] [view interactions] High throughput yes yes
ZN207_HUMAN [view interactions] High throughput no yes
CISY_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC8_HUMAN [view interactions] High throughput no yes
RM12_HUMAN [view interactions] High throughput no yes
PLST_HUMAN [view interactions] High throughput no yes
PDIA3_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A3_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A1_HUMAN [view interactions] High throughput no yes
CPSF6_HUMAN [view interactions] High throughput no yes
SND1_HUMAN [view entry] [view interactions] High throughput yes yes
CRNN_HUMAN [view interactions] High throughput no no
ISG15_HUMAN [view interactions] High throughput no no
CDK2_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
ASB9_HUMAN [view interactions] High throughput no no
GCP3_HUMAN [view interactions] High throughput no yes
STB5L_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
LRC15_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
BRAF_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
PPP6_HUMAN [view interactions] High throughput no yes
ARMC8_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
CGAS_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
NFX1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
FBLN3_HUMAN [view interactions] High throughput no no
EMC1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
EMC5_HUMAN [view interactions] High throughput no yes
DOCK8_HUMAN [view interactions] High throughput no yes
ARGAL_HUMAN [view interactions] High throughput no yes
DOCK9_HUMAN [view entry] [view interactions] High throughput yes yes
NMRL1_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
BASP1_HUMAN [view entry] [view interactions] High throughput yes yes
CALR_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
STMN1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
PTMS_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
PPIB_HUMAN [view entry] [view interactions] High throughput yes yes
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
DX39B_HUMAN [view interactions] High throughput no no
AN32B_HUMAN [view interactions] High throughput no yes
PGK1_HUMAN [view entry] [view interactions] High throughput yes yes
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
MIF_HUMAN [view entry] [view interactions] High throughput yes yes
PDIA4_HUMAN [view interactions] High throughput no yes
HMGN1_HUMAN [view interactions] High throughput no yes
PEBP1_HUMAN [view entry] [view interactions] High throughput yes yes
PGAM1_HUMAN [view entry] [view interactions] High throughput yes yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
ATIF1_HUMAN [view interactions] High throughput no yes
CH10_HUMAN [view interactions] High throughput no yes
ANXA2_HUMAN [view entry] [view interactions] High throughput yes no
AN32A_HUMAN [view interactions] High throughput no yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
PARK7_HUMAN [view entry] [view interactions] High throughput yes yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
HMGB2_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
OR1M1_HUMAN [view interactions] High throughput no no
TRI26_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
CLC4E_HUMAN [view interactions] High throughput no no
BAG1_HUMAN [view interactions] High throughput no yes
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
SOX2_HUMAN [view interactions] High throughput no yes
FBRL_HUMAN [view interactions] High throughput no yes
BCL6_HUMAN [view interactions] High throughput no no
BACH_HUMAN [view entry] [view interactions] High throughput yes yes
AIMP2_HUMAN [view interactions] High throughput no yes
HDAC6_HUMAN [view interactions] High throughput no yes
RNF8_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
CAVN3_HUMAN [view interactions] High throughput no no
INSR_HUMAN [view interactions] High throughput no yes
CDK7_HUMAN [view interactions] High throughput no yes
PARPT_HUMAN [view interactions] High throughput no no
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
TET5C_HUMAN [view interactions] High throughput no yes
DDX24_HUMAN [view interactions] High throughput no yes
ARC1B_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
SPOP_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
NDRG1_HUMAN [view entry] [view interactions] High throughput yes yes
HARS1_HUMAN [view interactions] High throughput no yes
PPT2_HUMAN [view interactions] High throughput no no
PUM1_HUMAN [view interactions] High throughput no yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
IQGA1_HUMAN [view entry] [view interactions] High throughput yes no
UN13D_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
GCN1_HUMAN [view interactions] High throughput no yes
PDCD6_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
PPA6_HUMAN [view interactions] High throughput no no
ECI1_HUMAN [view interactions] High throughput no yes
GABT_HUMAN [view interactions] High throughput no yes
MPPB_HUMAN [view interactions] High throughput no yes
AL7A1_HUMAN [view entry] [view interactions] High throughput yes no
NEUM_HUMAN [view entry] [view interactions] High throughput yes yes
SUCA_HUMAN [view entry] [view interactions] High throughput yes yes
SUCB2_HUMAN [view interactions] High throughput no no
ACSF2_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
HMCS1_HUMAN [view interactions] High throughput no yes
NNRE_HUMAN [view interactions] High throughput no yes
GSTO1_HUMAN [view entry] [view interactions] High throughput yes yes
ABHDA_HUMAN [view interactions] High throughput no yes
GUAA_HUMAN [view interactions] High throughput no no
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
PLGT3_HUMAN [view interactions] High throughput no no
NIT2_HUMAN [view interactions] High throughput no yes
PCKGM_HUMAN [view interactions] High throughput no no
MPPA_HUMAN [view interactions] High throughput no yes
SUCB1_HUMAN [view entry] [view interactions] High throughput yes yes
CCS_HUMAN [view interactions] High throughput no yes
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB18_HUMAN [view entry] [view interactions] High throughput yes yes
KCC1A_HUMAN [view entry] [view interactions] High throughput yes yes
ARK72_HUMAN [view entry] [view interactions] High throughput yes yes
SYNC_HUMAN [view interactions] High throughput no yes
FCL_HUMAN [view interactions] High throughput no yes
RABEK_HUMAN [view interactions] High throughput no yes
FBLI1_HUMAN [view interactions] High throughput no yes
AIDA_HUMAN [view interactions] High throughput no yes
DHTK1_HUMAN [view interactions] High throughput no no
AGR2_HUMAN [view interactions] High throughput no no
TNR6_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
PCDH7_HUMAN [view entry] [view interactions] High throughput yes no
RICTR_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
LAMC3_HUMAN [view interactions] High throughput no no
2AAB_HUMAN [view interactions] High throughput no yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
H2AX_HUMAN [view interactions] High throughput no yes
ATF2_HUMAN [view interactions] High throughput no yes
MET14_HUMAN [view interactions] High throughput no yes
POC5_HUMAN [view interactions] High throughput no yes
SH3G3_HUMAN [view entry] [view interactions] High throughput yes no
KPCD1_HUMAN [view interactions] High throughput no yes
FGR_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
PK3CA_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
TBX3_HUMAN [view interactions] High throughput no no
NEK10_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
SDHA_HUMAN [view interactions] High throughput no yes
TINF2_HUMAN [view interactions] High throughput no no
IRF2_HUMAN [view interactions] High throughput no yes
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
M3K7_HUMAN [view interactions] High throughput no yes
KPCD3_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
MYLK_HUMAN [view entry] [view interactions] High throughput yes no
NEK7_HUMAN [view interactions] High throughput no yes
SGK3_HUMAN [view interactions] High throughput no yes