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MP2K7_HUMAN

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Part of a non-canonical MAPK signaling pathway, composed of the upstream MAP3K12 kinase and downstream MAP kinases MAPK1/ERK2 and MAPK3/ERK1, that enhances the AP-1-mediated transcription of APP in response to APOE (PubMed). [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in MP2K7_HUMAN
GO:0000166 nucleotide binding 43.4783 4 yes
GO:0043168 anion binding 40.5797 4 yes
GO:0017076 purine nucleotide binding 39.1304 5 yes
GO:0032555 purine ribonucleotide binding 39.1304 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 39.1304 4 yes
GO:0005524 ATP binding 33.3333 5 yes
GO:0030554 adenyl nucleotide binding 33.3333 6 yes
GO:0032559 adenyl ribonucleotide binding 33.3333 5 yes
GO:0003723 RNA binding 27.5362 4 no
GO:0019900 kinase binding 26.0870 4 yes
GO:0043169 cation binding 26.0870 4 yes
GO:0046872 metal ion binding 24.6377 5 yes
GO:0019901 protein kinase binding 23.1884 5 yes
GO:0016301 kinase activity 18.8406 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 18.8406 4 yes
GO:0004674 protein serine/threonine kinase activity 13.0435 4 yes
GO:0106310 protein serine kinase activity 13.0435 4 yes
GO:0019902 phosphatase binding 8.6957 4 yes
GO:0019903 protein phosphatase binding 7.2464 5 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 5.7971 4 yes
GO:0004707 MAP kinase activity 4.3478 5 yes
GO:0004708 MAP kinase kinase activity 4.3478 5 yes
GO:0004713 protein tyrosine kinase activity 4.3478 4 yes
GO:0000287 magnesium ion binding 2.8986 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MP2K7_HUMAN
GO:0048522 positive regulation of cellular process 59.4203 4 yes
GO:0048523 negative regulation of cellular process 53.6232 4 no
GO:0010646 regulation of cell communication 50.7246 4 yes
GO:0031323 regulation of cellular metabolic process 50.7246 4 yes
GO:0080090 regulation of primary metabolic process 50.7246 4 yes
GO:0060255 regulation of macromolecule metabolic process 49.2754 4 yes
GO:0051128 regulation of cellular component organization 42.0290 4 yes
GO:0009966 regulation of signal transduction 42.0290 4 yes
GO:0031326 regulation of cellular biosynthetic process 39.1304 5 yes
GO:0051246 regulation of protein metabolic process 39.1304 5 yes
GO:0009889 regulation of biosynthetic process 39.1304 4 yes
GO:0009893 positive regulation of metabolic process 39.1304 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 36.2319 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 34.7826 5 yes
GO:0010468 regulation of gene expression 33.3333 6 yes
GO:0022607 cellular component assembly 33.3333 4 no
GO:0043067 regulation of programmed cell death 31.8841 4 yes
GO:0006996 organelle organization 31.8841 4 no
GO:0051049 regulation of transport 31.8841 4 no
GO:0042981 regulation of apoptotic process 30.4348 5 yes
GO:0048584 positive regulation of response to stimulus 30.4348 4 yes
GO:1902531 regulation of intracellular signal transduction 30.4348 5 yes
GO:0009892 negative regulation of metabolic process 30.4348 4 no
GO:0043412 macromolecule modification 30.4348 4 no
GO:0008104 protein localization 30.4348 4 no
GO:0051247 positive regulation of protein metabolic process 28.9855 6 yes
GO:0036211 protein modification process 28.9855 4 no
GO:0006796 phosphate-containing compound metabolic process 28.9855 4 yes
GO:0010647 positive regulation of cell communication 27.5362 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.5362 5 yes
GO:0023056 positive regulation of signaling 27.5362 4 yes
GO:0031325 positive regulation of cellular metabolic process 27.5362 5 yes
GO:0031399 regulation of protein modification process 27.5362 6 yes
GO:0060341 regulation of cellular localization 27.5362 4 no
GO:0019220 regulation of phosphate metabolic process 26.0870 6 yes
GO:0051174 regulation of phosphorus metabolic process 26.0870 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 24.6377 5 no
GO:0071702 organic substance transport 24.6377 4 no
GO:0031324 negative regulation of cellular metabolic process 24.6377 5 no
GO:0009967 positive regulation of signal transduction 23.1884 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 23.1884 6 yes
GO:0033043 regulation of organelle organization 23.1884 5 yes
GO:0051252 regulation of RNA metabolic process 23.1884 5 yes
GO:0043933 protein-containing complex organization 23.1884 4 no
GO:0071705 nitrogen compound transport 23.1884 4 no
GO:0032880 regulation of protein localization 23.1884 5 no
GO:0009894 regulation of catabolic process 23.1884 4 no
GO:0009891 positive regulation of biosynthetic process 23.1884 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 21.7391 6 yes
GO:0042325 regulation of phosphorylation 21.7391 7 yes
GO:0010648 negative regulation of cell communication 21.7391 5 no
GO:0023057 negative regulation of signaling 21.7391 4 no
GO:0043066 negative regulation of apoptotic process 21.7391 6 no
GO:0043069 negative regulation of programmed cell death 21.7391 5 no
GO:0015031 protein transport 21.7391 4 no
GO:0065003 protein-containing complex assembly 21.7391 5 no
GO:0051050 positive regulation of transport 21.7391 4 no
GO:0051130 positive regulation of cellular component organization 20.2899 5 yes
GO:2001141 regulation of RNA biosynthetic process 20.2899 6 yes
GO:0009968 negative regulation of signal transduction 20.2899 5 no
GO:0048585 negative regulation of response to stimulus 20.2899 4 no
GO:0051240 positive regulation of multicellular organismal process 20.2899 4 no
GO:0044087 regulation of cellular component biogenesis 20.2899 4 no
GO:0001932 regulation of protein phosphorylation 20.2899 7 yes
GO:0006355 regulation of DNA-templated transcription 20.2899 7 yes
GO:0016310 phosphorylation 18.8406 5 yes
GO:0071310 cellular response to organic substance 18.8406 4 yes
GO:0031401 positive regulation of protein modification process 17.3913 7 yes
GO:0043085 positive regulation of catalytic activity 17.3913 4 yes
GO:0141124 intracellular signaling cassette 17.3913 4 yes
GO:1902533 positive regulation of intracellular signal transduction 17.3913 6 yes
GO:0043408 regulation of MAPK cascade 15.9420 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 15.9420 5 yes
GO:0051338 regulation of transferase activity 15.9420 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 14.4928 6 yes
GO:0045937 positive regulation of phosphate metabolic process 14.4928 7 yes
GO:0000165 MAPK cascade 14.4928 5 yes
GO:0010638 positive regulation of organelle organization 13.0435 6 yes
GO:0042327 positive regulation of phosphorylation 13.0435 8 yes
GO:0043549 regulation of kinase activity 13.0435 5 yes
GO:1901701 cellular response to oxygen-containing compound 13.0435 4 yes
GO:0050776 regulation of immune response 11.5942 4 yes
GO:0051254 positive regulation of RNA metabolic process 11.5942 6 yes
GO:0001934 positive regulation of protein phosphorylation 11.5942 8 yes
GO:0006915 apoptotic process 11.5942 4 yes
GO:0043410 positive regulation of MAPK cascade 10.1449 7 yes
GO:0045859 regulation of protein kinase activity 10.1449 6 yes
GO:0045893 positive regulation of DNA-templated transcription 10.1449 8 yes
GO:0051347 positive regulation of transferase activity 10.1449 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 10.1449 7 yes
GO:0033674 positive regulation of kinase activity 8.6957 6 yes
GO:0033993 response to lipid 8.6957 4 yes
GO:0034097 response to cytokine 8.6957 4 yes
GO:0071345 cellular response to cytokine stimulus 8.6957 5 yes
GO:0043523 regulation of neuron apoptotic process 7.2464 6 yes
GO:0045860 positive regulation of protein kinase activity 7.2464 7 yes
GO:0046328 regulation of JNK cascade 7.2464 7 yes
GO:0051052 regulation of DNA metabolic process 7.2464 5 yes
GO:0051054 positive regulation of DNA metabolic process 7.2464 6 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 7.2464 7 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 7.2464 4 yes
GO:0007254 JNK cascade 7.2464 6 yes
GO:0033044 regulation of chromosome organization 5.7971 6 yes
GO:0051972 regulation of telomerase activity 5.7971 5 yes
GO:0051973 positive regulation of telomerase activity 5.7971 6 yes
GO:2000278 regulation of DNA biosynthetic process 5.7971 6 yes
GO:2000573 positive regulation of DNA biosynthetic process 5.7971 7 yes
GO:0038093 Fc receptor signaling pathway 4.3478 5 yes
GO:0043405 regulation of MAP kinase activity 4.3478 8 yes
GO:0043506 regulation of JUN kinase activity 4.3478 9 yes
GO:0046330 positive regulation of JNK cascade 4.3478 8 yes
GO:0070374 positive regulation of ERK1 and ERK2 cascade 4.3478 8 yes
GO:0071396 cellular response to lipid 4.3478 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 4.3478 7 yes
GO:0009416 response to light stimulus 4.3478 4 yes
GO:0031098 stress-activated protein kinase signaling cascade 2.8986 4 yes
GO:0032204 regulation of telomere maintenance 2.8986 6 yes
GO:0032206 positive regulation of telomere maintenance 2.8986 7 yes
GO:0032210 regulation of telomere maintenance via telomerase 2.8986 7 yes
GO:0032212 positive regulation of telomere maintenance via telomerase 2.8986 8 yes
GO:0032496 response to lipopolysaccharide 2.8986 4 yes
GO:0034612 response to tumor necrosis factor 2.8986 5 yes
GO:0038095 Fc-epsilon receptor signaling pathway 2.8986 6 yes
GO:0043406 positive regulation of MAP kinase activity 2.8986 8 yes
GO:0043507 positive regulation of JUN kinase activity 2.8986 9 yes
GO:0051403 stress-activated MAPK cascade 2.8986 5 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 2.8986 8 yes
GO:1904353 regulation of telomere capping 2.8986 7 yes
GO:1904355 positive regulation of telomere capping 2.8986 8 yes
GO:1904356 regulation of telomere maintenance via telomere lengthening 2.8986 7 yes
GO:1904358 positive regulation of telomere maintenance via telomere lengthening 2.8986 8 yes
GO:2000671 regulation of motor neuron apoptotic process 2.8986 7 yes
GO:2001252 positive regulation of chromosome organization 2.8986 7 yes
GO:0002237 response to molecule of bacterial origin 2.8986 4 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
M3K13_HUMAN [view interactions] Low throughput no yes
MK14_HUMAN [view interactions] Low throughput no yes
JUN_HUMAN [view interactions] Low throughput no yes
MK10_HUMAN [view entry] [view interactions] Low throughput yes yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
TRIB3_HUMAN [view interactions] Low throughput no yes
CFLAR_HUMAN [view interactions] Low throughput no yes
M3K1_HUMAN [view interactions] Low throughput no yes
M3K5_HUMAN [view interactions] Low throughput no yes
M3K7_HUMAN [view interactions] Low throughput no yes
LRRK2_HUMAN [view interactions] Low throughput no yes
GA45B_HUMAN [view interactions] Low throughput no yes
VRK2_HUMAN [view interactions] Low throughput no no
JIP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MK08_HUMAN [view interactions] Low throughput no yes
M3K20_HUMAN [view interactions] Low throughput no yes
DUS22_HUMAN [view interactions] Low throughput no yes
JIP2_HUMAN [view entry] [view interactions] Low throughput yes no
DUS19_HUMAN [view interactions] Low throughput no yes
JIP3_HUMAN [view entry] [view interactions] Low throughput yes yes
M3K12_HUMAN [view entry] [view interactions] Low throughput yes yes
M3K2_HUMAN [view interactions] Low throughput no yes
MP2K4_HUMAN [view interactions] Low throughput no yes
KPCT_HUMAN [view interactions] Low throughput no no
BCL10_HUMAN [view interactions] Low throughput no yes
WDR6_HUMAN [view entry] [view interactions] Low throughput yes yes
RASN_HUMAN [view entry] [view interactions] Low throughput yes no
RBP2_HUMAN [view interactions] Low throughput no yes
BRAF_HUMAN [view entry] [view interactions] Low throughput yes yes
ZDH17_HUMAN [view entry] [view interactions] Low throughput yes yes
TP8L1_HUMAN [view interactions] Low throughput no no
MK09_HUMAN [view interactions] Low throughput no yes
M3K4_HUMAN [view interactions] Low throughput no yes
M3K11_HUMAN [view interactions] Low throughput no yes
M3K3_HUMAN [view interactions] High throughput no no
ALDOA_HUMAN [view entry] [view interactions] High throughput yes no
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
CH10_HUMAN [view interactions] High throughput no yes
ILKAP_HUMAN [view interactions] High throughput no yes
KS6A1_HUMAN [view entry] [view interactions] High throughput yes yes
KS6A2_HUMAN [view interactions] High throughput no yes
P85A_HUMAN [view interactions] High throughput no yes
SMHD1_HUMAN [view interactions] High throughput no yes
EVPL_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
HACL2_HUMAN [view interactions] High throughput no yes
HAX1_HUMAN [view interactions] High throughput no no
AIP_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
SC16A_HUMAN [view interactions] High throughput no yes
PFD6_HUMAN [view interactions] High throughput no yes
CALU_HUMAN [view interactions] High throughput no yes
ACSL4_HUMAN [view entry] [view interactions] High throughput yes yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5H_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
AHSA1_HUMAN [view entry] [view interactions] High throughput yes yes
ACSL3_HUMAN [view entry] [view interactions] High throughput yes yes
DHE3_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
ANXA5_HUMAN [view entry] [view interactions] High throughput yes no
CN37_HUMAN [view entry] [view interactions] High throughput yes no
GLU2B_HUMAN [view interactions] High throughput no yes
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
PFKAL_HUMAN [view entry] [view interactions] High throughput yes yes
RPAB1_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
DNJB1_HUMAN [view entry] [view interactions] High throughput yes yes
PYR1_HUMAN [view entry] [view interactions] High throughput yes yes
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
LONM_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
ATPO_HUMAN [view interactions] High throughput no yes
F10A1_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
AL3A2_HUMAN [view entry] [view interactions] High throughput yes yes
KAD2_HUMAN [view interactions] High throughput no no
ATPK_HUMAN [view interactions] High throughput no yes
DCAF7_HUMAN [view interactions] High throughput no yes
PRKDC_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP4_HUMAN [view entry] [view interactions] High throughput yes yes
RM49_HUMAN [view interactions] High throughput no yes
FKBP5_HUMAN [view interactions] High throughput no yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
RCN2_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
TEBP_HUMAN [view interactions] High throughput no yes
AAAT_HUMAN [view interactions] High throughput no no
DDB1_HUMAN [view interactions] High throughput no yes
NU188_HUMAN [view interactions] High throughput no yes
RB6I2_HUMAN [view entry] [view interactions] High throughput yes yes
PCAT1_HUMAN [view interactions] High throughput no yes
GCN1_HUMAN [view interactions] High throughput no yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
MMS19_HUMAN [view interactions] High throughput no yes
DJC10_HUMAN [view interactions] High throughput no yes
METH_HUMAN [view interactions] High throughput no yes
CLPB_HUMAN [view interactions] High throughput no yes
CPVL_HUMAN [view interactions] High throughput no no
TRABD_HUMAN [view interactions] High throughput no yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
SDF2L_HUMAN [view interactions] High throughput no yes
RM16_HUMAN [view interactions] High throughput no yes
AKP8L_HUMAN [view interactions] High throughput no yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
SGT1_HUMAN [view interactions] High throughput no no
RT23_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
YTHD2_HUMAN [view interactions] High throughput no yes
TF3C3_HUMAN [view interactions] High throughput no no
SIM26_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
ATF4_HUMAN [view interactions] High throughput no no
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
LPXN_HUMAN [view interactions] High throughput no yes
ARRC_HUMAN [view interactions] High throughput no no
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
TNR5_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
FOXP3_HUMAN [view interactions] High throughput no no
C4BPB_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
SACA1_HUMAN [view interactions] High throughput no no
ANTR1_HUMAN [view interactions] High throughput no no
DLK1_HUMAN [view interactions] High throughput no no
VSIG4_HUMAN [view interactions] High throughput no no
I13R2_HUMAN [view interactions] High throughput no no
LAMP3_HUMAN [view interactions] High throughput no no
PROZ_HUMAN [view interactions] High throughput no no
TPC2_HUMAN [view interactions] High throughput no no
ADA32_HUMAN [view interactions] High throughput no no
PCDG5_HUMAN [view interactions] High throughput no yes
LRP1_HUMAN [view entry] [view interactions] High throughput yes yes
LTN1_HUMAN [view interactions] High throughput no no
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
BRD1_HUMAN [view interactions] High throughput no yes
SP100_HUMAN [view interactions] High throughput no no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
INS_HUMAN [view interactions] High throughput no no
SH3R3_HUMAN [view interactions] High throughput no yes
PCDB6_HUMAN [view entry] [view interactions] High throughput yes no
S39A7_HUMAN [view interactions] High throughput no yes
GLPA_HUMAN [view interactions] High throughput no no
FRIL_HUMAN [view interactions] High throughput no yes
NK3R_HUMAN [view interactions] High throughput no no
CF062_HUMAN [view interactions] High throughput no yes
UGGG2_HUMAN [view interactions] High throughput no no
GP182_HUMAN [view interactions] High throughput no no
HNRC2_HUMAN [view interactions] High throughput no no
TCPQM_HUMAN [view interactions] High throughput no no
PP2BA_HUMAN [view entry] [view interactions] High throughput yes yes
CANB2_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
NPAS1_HUMAN [view interactions] High throughput no no
EFMT3_HUMAN [view interactions] High throughput no no
FCN3_HUMAN [view interactions] High throughput no no
ERG28_HUMAN [view interactions] High throughput no yes
F174C_HUMAN [view interactions] High throughput no yes
APC11_HUMAN [view interactions] High throughput no yes
PDLI7_HUMAN [view entry] [view interactions] High throughput yes no
MOC2B_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
TRI67_HUMAN [view interactions] High throughput no no
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
CL16A_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
DMPK_HUMAN [view interactions] High throughput no yes
PI2R_HUMAN [view interactions] High throughput no no
KCRM_HUMAN [view interactions] High throughput no no
PROD_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
ITB7_HUMAN [view interactions] High throughput no no
FABP4_HUMAN [view interactions] High throughput no no
UFO_HUMAN [view interactions] High throughput no no
M3K10_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
SRBP2_HUMAN [view interactions] High throughput no yes