Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PROD_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Converts proline to delta-1-pyrroline-5-carboxylate. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PROD_HUMAN
GO:0000166 nucleotide binding 100.0000 4 yes
GO:0043168 anion binding 100.0000 4 yes
GO:0017076 purine nucleotide binding 85.7143 5 no
GO:0032555 purine ribonucleotide binding 85.7143 4 no
GO:0035639 purine ribonucleoside triphosphate binding 85.7143 4 no
GO:0005524 ATP binding 71.4286 5 no
GO:0030554 adenyl nucleotide binding 71.4286 6 no
GO:0032559 adenyl ribonucleotide binding 71.4286 5 no
GO:0016462 pyrophosphatase activity 57.1429 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 57.1429 4 no
GO:0016887 ATP hydrolysis activity 57.1429 7 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 57.1429 6 no
GO:0031625 ubiquitin protein ligase binding 42.8571 5 no
GO:0044389 ubiquitin-like protein ligase binding 42.8571 4 no
GO:0019900 kinase binding 28.5714 4 no
GO:0019901 protein kinase binding 28.5714 5 no
GO:0043169 cation binding 28.5714 4 no
GO:0046872 metal ion binding 28.5714 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PROD_HUMAN
GO:0006986 response to unfolded protein 57.1429 4 no
GO:0051084 de novo post-translational protein folding 57.1429 4 no
GO:0051085 chaperone cofactor-dependent protein refolding 57.1429 4 no
GO:0031323 regulation of cellular metabolic process 42.8571 4 no
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0051128 regulation of cellular component organization 42.8571 4 no
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 28.5714 4 yes
GO:0010646 regulation of cell communication 28.5714 4 yes
GO:0042981 regulation of apoptotic process 28.5714 5 yes
GO:0043067 regulation of programmed cell death 28.5714 4 yes
GO:0043523 regulation of neuron apoptotic process 28.5714 6 yes
GO:1901565 organonitrogen compound catabolic process 28.5714 4 yes
GO:1902531 regulation of intracellular signal transduction 28.5714 5 yes
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0001934 positive regulation of protein phosphorylation 28.5714 8 no
GO:0006996 organelle organization 28.5714 4 no
GO:0009893 positive regulation of metabolic process 28.5714 4 no
GO:0010562 positive regulation of phosphorus metabolic process 28.5714 6 no
GO:0010604 positive regulation of macromolecule metabolic process 28.5714 5 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0022411 cellular component disassembly 28.5714 4 no
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0031401 positive regulation of protein modification process 28.5714 7 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0042327 positive regulation of phosphorylation 28.5714 8 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0045937 positive regulation of phosphate metabolic process 28.5714 7 no
GO:0048523 negative regulation of cellular process 28.5714 4 no
GO:0051129 negative regulation of cellular component organization 28.5714 5 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0051246 regulation of protein metabolic process 28.5714 5 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0006355 regulation of DNA-templated transcription 28.5714 7 no
GO:0006796 phosphate-containing compound metabolic process 28.5714 4 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0010468 regulation of gene expression 28.5714 6 no
GO:0010556 regulation of macromolecule biosynthetic process 28.5714 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0033993 response to lipid 28.5714 4 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:0071310 cellular response to organic substance 28.5714 4 no
GO:0071396 cellular response to lipid 28.5714 5 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0032880 regulation of protein localization 28.5714 5 no
GO:0060341 regulation of cellular localization 28.5714 4 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
S23A3_HUMAN [view interactions] High throughput no no
BRAP_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
HSP72_HUMAN [view entry] [view interactions] High throughput yes no
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
KPRP_HUMAN [view interactions] High throughput no no
TUSC2_HUMAN [view interactions] High throughput no no
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
THTR_HUMAN [view interactions] High throughput no yes
BCAT2_HUMAN [view interactions] High throughput no no
ERBB3_HUMAN [view interactions] High throughput no yes
ACY1_HUMAN [view interactions] High throughput no no
CAN11_HUMAN [view interactions] High throughput no no