HS71L_HUMAN
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed). Positive regulator of PRKN translocation to damaged mitochondria (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI001097 | LIG_TPR | LIG | 638 | 641 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in HS71L_HUMAN |
---|---|---|---|---|
GO:0031625 | ubiquitin protein ligase binding | 29.1667 | 5 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 29.1667 | 4 | yes |
GO:0017076 | purine nucleotide binding | 28.1250 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 22.9167 | 5 | yes |
GO:0005524 | ATP binding | 19.7917 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 19.7917 | 5 | yes |
GO:0016462 | pyrophosphatase activity | 17.7083 | 5 | yes |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 17.7083 | 4 | yes |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 17.7083 | 6 | yes |
GO:0016887 | ATP hydrolysis activity | 12.5000 | 7 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in HS71L_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 54.1667 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 53.1250 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 51.0417 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 50.0000 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
GO:0048523 | negative regulation of cellular process | 42.7083 | 4 | no |
GO:0051128 | regulation of cellular component organization | 42.7083 | 4 | no |
GO:0006996 | organelle organization | 41.6667 | 4 | no |
GO:0010468 | regulation of gene expression | 40.6250 | 5 | no |
GO:0010646 | regulation of cell communication | 38.5417 | 4 | no |
GO:0008104 | protein localization | 37.5000 | 4 | no |
GO:0009966 | regulation of signal transduction | 37.5000 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 36.4583 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 36.4583 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 36.4583 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 36.4583 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 35.4167 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 35.4167 | 5 | no |
GO:0022607 | cellular component assembly | 34.3750 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 34.3750 | 5 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 33.3333 | 5 | no |
GO:0071702 | organic substance transport | 33.3333 | 4 | no |
GO:0071705 | nitrogen compound transport | 33.3333 | 4 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 33.3333 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0010941 | regulation of cell death | 33.3333 | 4 | no |
GO:0042981 | regulation of apoptotic process | 31.2500 | 6 | no |
GO:0043067 | regulation of programmed cell death | 31.2500 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 30.2083 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.2083 | 5 | no |
GO:1902531 | regulation of intracellular signal transduction | 30.2083 | 5 | no |
GO:0015031 | protein transport | 29.1667 | 4 | no |
GO:0031399 | regulation of protein modification process | 29.1667 | 6 | no |
GO:0006355 | regulation of DNA-templated transcription | 28.1250 | 6 | no |
GO:0051252 | regulation of RNA metabolic process | 28.1250 | 5 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 28.1250 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 28.1250 | 6 | no |
GO:0031324 | negative regulation of cellular metabolic process | 28.1250 | 5 | no |
GO:0043933 | protein-containing complex organization | 27.0833 | 4 | no |
GO:0009894 | regulation of catabolic process | 27.0833 | 4 | no |
GO:0051049 | regulation of transport | 26.0417 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 26.0417 | 5 | no |
GO:0060341 | regulation of cellular localization | 25.0000 | 4 | yes |
GO:0071310 | cellular response to organic substance | 25.0000 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 25.0000 | 4 | no |
GO:0051248 | negative regulation of protein metabolic process | 25.0000 | 6 | no |
GO:0065003 | protein-containing complex assembly | 23.9583 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 23.9583 | 6 | no |
GO:0043066 | negative regulation of apoptotic process | 23.9583 | 7 | no |
GO:0043069 | negative regulation of programmed cell death | 23.9583 | 6 | no |
GO:0060548 | negative regulation of cell death | 23.9583 | 5 | no |
GO:0033043 | regulation of organelle organization | 22.9167 | 5 | no |
GO:0009967 | positive regulation of signal transduction | 22.9167 | 5 | no |
GO:0016192 | vesicle-mediated transport | 22.9167 | 4 | yes |
GO:0036211 | protein modification process | 21.8750 | 4 | no |
GO:0043412 | macromolecule modification | 21.8750 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 21.8750 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 21.8750 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 21.8750 | 5 | no |
GO:0051338 | regulation of transferase activity | 21.8750 | 4 | no |
GO:0080134 | regulation of response to stress | 21.8750 | 4 | no |
GO:0030162 | regulation of proteolysis | 21.8750 | 6 | no |
GO:0031329 | regulation of cellular catabolic process | 21.8750 | 5 | no |
GO:0010648 | negative regulation of cell communication | 21.8750 | 5 | no |
GO:0023057 | negative regulation of signaling | 21.8750 | 4 | no |
GO:0006886 | intracellular protein transport | 20.8333 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 20.8333 | 4 | no |
GO:0032880 | regulation of protein localization | 19.7917 | 5 | yes |
GO:0006986 | response to unfolded protein | 18.7500 | 4 | yes |
GO:0051050 | positive regulation of transport | 13.5417 | 4 | yes |
GO:0070201 | regulation of establishment of protein localization | 13.5417 | 6 | yes |
GO:0032386 | regulation of intracellular transport | 13.5417 | 5 | yes |
GO:0051223 | regulation of protein transport | 11.4583 | 5 | yes |
GO:0035967 | cellular response to topologically incorrect protein | 10.4167 | 4 | yes |
GO:1903829 | positive regulation of protein localization | 10.4167 | 5 | yes |
GO:0034620 | cellular response to unfolded protein | 9.3750 | 5 | yes |
GO:0051084 | de novo post-translational protein folding | 9.3750 | 4 | yes |
GO:0051085 | chaperone cofactor-dependent protein refolding | 9.3750 | 4 | yes |
GO:0033157 | regulation of intracellular protein transport | 8.3333 | 6 | yes |
GO:1904951 | positive regulation of establishment of protein localization | 8.3333 | 6 | yes |
GO:0051222 | positive regulation of protein transport | 7.2917 | 5 | yes |
GO:0032388 | positive regulation of intracellular transport | 7.2917 | 5 | yes |
GO:0090316 | positive regulation of intracellular protein transport | 6.2500 | 6 | yes |
GO:1903533 | regulation of protein targeting | 5.2083 | 7 | yes |
GO:1903747 | regulation of establishment of protein localization to mitochondrion | 5.2083 | 7 | yes |
GO:1903214 | regulation of protein targeting to mitochondrion | 3.1250 | 8 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in HS71L_HUMAN |
---|---|---|---|---|
DOID:1289 | neurodegenerative disease | 2.0833 | 4 | no |
DOID:331 | central nervous system disease | 2.0833 | 3 | no |
DOID:0050700 | cardiomyopathy | 2.0833 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 2.0833 | 5 | no |
DOID:0080000 | muscular disease | 2.0833 | 3 | no |
DOID:0080307 | myofibrillar myopathy | 2.0833 | 6 | no |
DOID:114 | heart disease | 2.0833 | 3 | no |
DOID:12930 | dilated cardiomyopathy | 2.0833 | 6 | no |
DOID:423 | myopathy | 2.0833 | 5 | no |
DOID:66 | muscle tissue disease | 2.0833 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
P53_HUMAN | [view interactions] | Low throughput | no | no |
OLR1_HUMAN | [view interactions] | Low throughput | no | no |
RN123_HUMAN | [view interactions] | Low throughput | no | yes |
HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
AMFR_HUMAN | [view interactions] | Low throughput | no | yes |
GLUT4_HUMAN | [view interactions] | High throughput | no | no |
ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCP1B_HUMAN | [view interactions] | High throughput | no | yes |
HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H2AX_HUMAN | [view interactions] | High throughput | no | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITA2B_HUMAN | [view interactions] | High throughput | no | no |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRAP_HUMAN | [view interactions] | High throughput | no | no |
RM01_HUMAN | [view interactions] | High throughput | no | yes |
BAG4_HUMAN | [view interactions] | High throughput | no | yes |
NDUB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
HACD3_HUMAN | [view interactions] | High throughput | no | yes |
CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
TPX2_HUMAN | [view interactions] | High throughput | no | yes |
K2013_HUMAN | [view interactions] | High throughput | no | yes |
DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FIGL1_HUMAN | [view interactions] | High throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEK4_HUMAN | [view interactions] | High throughput | no | yes |
TOM22_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
THIOM_HUMAN | [view interactions] | High throughput | no | yes |
MECOM_HUMAN | [view interactions] | High throughput | no | yes |
NU214_HUMAN | [view interactions] | High throughput | no | no |
CRY1_HUMAN | [view interactions] | High throughput | no | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
RIN3_HUMAN | [view interactions] | High throughput | no | yes |
NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
JAZF1_HUMAN | [view interactions] | High throughput | no | yes |
ATPA_HUMAN | [view interactions] | High throughput | no | yes |
H15_HUMAN | [view interactions] | High throughput | no | no |
KGD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TIM14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIR1_HUMAN | [view interactions] | High throughput | no | yes |
ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIR3_HUMAN | [view interactions] | High throughput | no | yes |
GLYC_HUMAN | [view interactions] | High throughput | no | no |
CENPC_HUMAN | [view interactions] | High throughput | no | no |
STML2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SET_HUMAN | [view interactions] | High throughput | no | yes |
PIGS_HUMAN | [view interactions] | High throughput | no | yes |
DJC12_HUMAN | [view interactions] | High throughput | no | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBP2_HUMAN | [view interactions] | High throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCC1D_HUMAN | [view interactions] | High throughput | no | yes |
MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUCB2_HUMAN | [view interactions] | High throughput | no | yes |
DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GDS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI38_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K8_HUMAN | [view interactions] | High throughput | no | yes |
TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
REL_HUMAN | [view interactions] | High throughput | no | yes |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
IKBA_HUMAN | [view interactions] | High throughput | no | yes |
CLPP_HUMAN | [view interactions] | High throughput | no | yes |
IKBB_HUMAN | [view interactions] | High throughput | no | no |
DNJB8_HUMAN | [view interactions] | High throughput | no | no |
IKBE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TOM34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IKKB_HUMAN | [view interactions] | High throughput | no | yes |
STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEMO_HUMAN | [view interactions] | High throughput | no | yes |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TANK_HUMAN | [view interactions] | High throughput | no | yes |
DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M3K1_HUMAN | [view interactions] | High throughput | no | yes |
F10A1_HUMAN | [view interactions] | High throughput | no | yes |
M3K3_HUMAN | [view interactions] | High throughput | no | no |
DYR2_HUMAN | [view interactions] | High throughput | no | yes |
NFKB2_HUMAN | [view interactions] | High throughput | no | yes |
M3K14_HUMAN | [view interactions] | High throughput | no | yes |
RELB_HUMAN | [view interactions] | High throughput | no | yes |
RIPK1_HUMAN | [view interactions] | High throughput | no | yes |
RIPK2_HUMAN | [view interactions] | High throughput | no | yes |
RIPK3_HUMAN | [view interactions] | High throughput | no | no |
TAB1_HUMAN | [view interactions] | High throughput | no | yes |
TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
TNR1B_HUMAN | [view interactions] | High throughput | no | no |
TRADD_HUMAN | [view interactions] | High throughput | no | yes |
TRAF1_HUMAN | [view interactions] | High throughput | no | no |
TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
CSN5_HUMAN | [view interactions] | High throughput | no | yes |
CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CUL1_HUMAN | [view interactions] | High throughput | no | yes |
CUL4A_HUMAN | [view interactions] | High throughput | no | no |
DCNL1_HUMAN | [view interactions] | High throughput | no | yes |
CUL2_HUMAN | [view interactions] | High throughput | no | yes |
CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
CSN6_HUMAN | [view interactions] | High throughput | no | yes |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
AKT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STK4_HUMAN | [view interactions] | High throughput | no | yes |
NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
CC28B_HUMAN | [view interactions] | High throughput | no | no |
HSF1_HUMAN | [view interactions] | High throughput | no | yes |
MARE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
REC8_HUMAN | [view interactions] | High throughput | no | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
ACTS_HUMAN | [view interactions] | High throughput | no | no |
M3K7_HUMAN | [view interactions] | High throughput | no | yes |
TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
NEK8_HUMAN | [view interactions] | High throughput | no | yes |
NINL_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTPRF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
PSA3_HUMAN | [view interactions] | High throughput | no | no |
PCKGC_HUMAN | [view interactions] | High throughput | no | no |
SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
CBL_HUMAN | [view interactions] | High throughput | no | yes |
UBS3B_HUMAN | [view interactions] | High throughput | no | yes |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCP1A_HUMAN | [view interactions] | High throughput | no | yes |
MT21A_HUMAN | [view interactions] | High throughput | no | yes |
EFMT3_HUMAN | [view interactions] | High throughput | no | no |
MT21C_HUMAN | [view interactions] | High throughput | no | no |
MET22_HUMAN | [view interactions] | High throughput | no | yes |
UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
ZBTB1_HUMAN | [view interactions] | High throughput | no | no |
STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AIRE_HUMAN | [view interactions] | High throughput | no | no |
CDC20_HUMAN | [view interactions] | High throughput | no | no |
CP250_HUMAN | [view interactions] | High throughput | no | no |
CEP57_HUMAN | [view interactions] | High throughput | no | yes |
NEDD1_HUMAN | [view interactions] | High throughput | no | yes |
TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SIR6_HUMAN | [view interactions] | High throughput | no | yes |
CCNI2_HUMAN | [view interactions] | High throughput | no | no |
CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
LGAT1_HUMAN | [view interactions] | High throughput | no | no |
LRC28_HUMAN | [view interactions] | High throughput | no | yes |
POC1A_HUMAN | [view interactions] | High throughput | no | yes |
VASH1_HUMAN | [view interactions] | High throughput | no | yes |
BACD2_HUMAN | [view interactions] | High throughput | no | no |
BACD1_HUMAN | [view interactions] | High throughput | no | no |
DND1_HUMAN | [view interactions] | High throughput | no | no |
EPN3_HUMAN | [view interactions] | High throughput | no | no |
CP2W1_HUMAN | [view interactions] | High throughput | no | no |
AL3B1_HUMAN | [view interactions] | High throughput | no | yes |
SMAP1_HUMAN | [view interactions] | High throughput | no | yes |
TB22A_HUMAN | [view interactions] | High throughput | no | yes |
TTLL3_HUMAN | [view interactions] | High throughput | no | yes |
CC117_HUMAN | [view interactions] | High throughput | no | yes |
DEN2D_HUMAN | [view interactions] | High throughput | no | yes |
CDK3_HUMAN | [view interactions] | High throughput | no | no |
PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIFC1_HUMAN | [view interactions] | High throughput | no | yes |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ID2_HUMAN | [view interactions] | High throughput | no | no |
GAN_HUMAN | [view interactions] | High throughput | no | yes |
SKI_HUMAN | [view interactions] | High throughput | no | yes |
MCM5_HUMAN | [view interactions] | High throughput | no | no |
MCM2_HUMAN | [view interactions] | High throughput | no | no |
UHRF2_HUMAN | [view interactions] | High throughput | no | no |
DPF3_HUMAN | [view interactions] | High throughput | no | yes |
EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
CCND2_HUMAN | [view interactions] | High throughput | no | yes |
UBE2S_HUMAN | [view interactions] | High throughput | no | no |
BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN7_HUMAN | [view interactions] | High throughput | no | no |
FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
CHD4_HUMAN | [view interactions] | High throughput | no | yes |
SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
LARP7_HUMAN | [view interactions] | High throughput | no | yes |
AGR2_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
CNTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
NEK2_HUMAN | [view interactions] | High throughput | no | no |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CCND1_HUMAN | [view interactions] | High throughput | no | yes |
TET2_HUMAN | [view interactions] | High throughput | no | yes |
ATX3_HUMAN | [view interactions] | High throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTMA_HUMAN | [view interactions] | High throughput | no | yes |
BRD7_HUMAN | [view interactions] | High throughput | no | yes |
HAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARI2_HUMAN | [view interactions] | High throughput | no | no |
CUL7_HUMAN | [view interactions] | High throughput | no | yes |
PINK1_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
ODFP2_HUMAN | [view interactions] | High throughput | no | no |
RBM39_HUMAN | [view interactions] | High throughput | no | yes |
DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DJB11_HUMAN | [view interactions] | High throughput | no | yes |
DJB12_HUMAN | [view interactions] | High throughput | no | yes |
DJB14_HUMAN | [view interactions] | High throughput | no | yes |
DNJB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJB5_HUMAN | [view interactions] | High throughput | no | yes |
DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC3_HUMAN | [view interactions] | High throughput | no | yes |
DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HPBP1_HUMAN | [view interactions] | High throughput | no | yes |
FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EDRF1_HUMAN | [view interactions] | High throughput | no | no |
DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASNS_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PR40A_HUMAN | [view interactions] | High throughput | no | yes |
MLF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP11_HUMAN | [view interactions] | High throughput | no | yes |
IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARFP1_HUMAN | [view interactions] | High throughput | no | no |
SNW1_HUMAN | [view interactions] | High throughput | no | yes |
FZR1_HUMAN | [view interactions] | High throughput | no | no |
ELP4_HUMAN | [view interactions] | High throughput | no | yes |
RETST_HUMAN | [view interactions] | High throughput | no | yes |
PROD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SCMC3_HUMAN | [view interactions] | High throughput | no | yes |
CC142_HUMAN | [view interactions] | High throughput | no | no |
ABH15_HUMAN | [view interactions] | High throughput | no | yes |
HAUS5_HUMAN | [view interactions] | High throughput | no | yes |
FCSK_HUMAN | [view interactions] | High throughput | no | yes |
KLH34_HUMAN | [view interactions] | High throughput | no | no |
SOLH1_HUMAN | [view interactions] | High throughput | no | no |
URGCP_HUMAN | [view interactions] | High throughput | no | yes |
ANKK1_HUMAN | [view interactions] | High throughput | no | no |
OPALI_HUMAN | [view interactions] | High throughput | no | yes |
MTU1_HUMAN | [view interactions] | High throughput | no | no |
CALI_HUMAN | [view interactions] | High throughput | no | no |
ILK_HUMAN | [view interactions] | High throughput | no | no |
TEDC1_HUMAN | [view interactions] | High throughput | no | no |
SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
DVL2_HUMAN | [view interactions] | High throughput | no | yes |
ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
BAG1_HUMAN | [view interactions] | High throughput | no | yes |
MED19_HUMAN | [view interactions] | High throughput | no | yes |
FBX43_HUMAN | [view interactions] | High throughput | no | no |
MED10_HUMAN | [view interactions] | High throughput | no | no |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
MED9_HUMAN | [view interactions] | High throughput | no | no |
CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MED29_HUMAN | [view interactions] | High throughput | no | no |
DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
MED26_HUMAN | [view interactions] | High throughput | no | no |
FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
MRGBP_HUMAN | [view interactions] | High throughput | no | no |
GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S10A1_HUMAN | [view interactions] | Computational | no | yes |
AAAS_HUMAN | [view interactions] | Computational | no | yes |
TPR_HUMAN | [view interactions] | Computational | no | yes |
NUP58_HUMAN | [view interactions] | Computational | no | yes |
NUP50_HUMAN | [view interactions] | Computational | no | yes |
NU188_HUMAN | [view interactions] | Computational | no | yes |
DNJC2_HUMAN | [view interactions] | Computational | no | yes |
NDC1_HUMAN | [view interactions] | Computational | no | yes |
NUP88_HUMAN | [view interactions] | Computational | no | yes |
NU205_HUMAN | [view interactions] | Computational | no | no |
SEH1_HUMAN | [view interactions] | Computational | no | no |
NUP42_HUMAN | [view interactions] | Computational | no | no |
SEC13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NU155_HUMAN | [view interactions] | Computational | no | yes |
NUP37_HUMAN | [view interactions] | Computational | no | yes |
NU153_HUMAN | [view interactions] | Computational | no | yes |
CBP_HUMAN | [view interactions] | Computational | no | yes |
P121C_HUMAN | [view interactions] | Computational | no | yes |
NUP85_HUMAN | [view interactions] | Computational | no | yes |
NUP93_HUMAN | [view interactions] | Computational | no | yes |
DNJA4_HUMAN | [view interactions] | Computational | no | yes |
NU107_HUMAN | [view interactions] | Computational | no | no |
NU133_HUMAN | [view interactions] | Computational | no | yes |
P121A_HUMAN | [view interactions] | Computational | no | yes |
EP300_HUMAN | [view interactions] | Computational | no | yes |
NUP35_HUMAN | [view interactions] | Computational | no | yes |
NUP62_HUMAN | [view interactions] | Computational | no | yes |
PO210_HUMAN | [view interactions] | Computational | no | yes |
NUP43_HUMAN | [view interactions] | Computational | no | yes |
AROS_HUMAN | [view interactions] | Computational | no | yes |
NUP54_HUMAN | [view interactions] | Computational | no | yes |
HS90B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAE1L_HUMAN | [view interactions] | Computational | no | no |
CRYAB_HUMAN | [view entry] [view interactions] | Computational | yes | no |
HS74L_HUMAN | [view entry] [view interactions] | Computational | yes | no |
HSPB8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TLR2_HUMAN | [view interactions] | Computational | no | no |
HSBP1_HUMAN | [view interactions] | Computational | no | no |
NU160_HUMAN | [view interactions] | Computational | no | no |
NUP98_HUMAN | [view interactions] | Computational | no | no |