HS105_HUMAN
Evidence for PS localization
Functions
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in HS105_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 36.1290 | 4 | yes |
| GO:0043168 | anion binding | 34.8387 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 34.1935 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 34.1935 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 33.5484 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 30.3226 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 30.3226 | 5 | yes |
| GO:0005524 | ATP binding | 29.6774 | 5 | yes |
| GO:0003723 | RNA binding | 24.5161 | 4 | no |
| GO:0043169 | cation binding | 22.5806 | 4 | no |
| GO:0046872 | metal ion binding | 22.5806 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 20.6452 | 4 | no |
| GO:0015631 | tubulin binding | 9.0323 | 4 | yes |
| GO:0043014 | alpha-tubulin binding | 1.9355 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in HS105_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.8387 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 54.1935 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 52.2581 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 50.9677 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.3871 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 44.5161 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 42.5806 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 41.9355 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 41.9355 | 5 | yes |
| GO:0006996 | organelle organization | 40.6452 | 4 | no |
| GO:0010646 | regulation of cell communication | 40.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 39.3548 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 36.7742 | 5 | no |
| GO:0009966 | regulation of signal transduction | 34.1935 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 32.9032 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 32.2581 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 31.6129 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 31.6129 | 5 | no |
| GO:0022607 | cellular component assembly | 31.6129 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.3226 | 5 | no |
| GO:0008104 | protein localization | 29.6774 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.7419 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 27.7419 | 5 | no |
| GO:0051049 | regulation of transport | 27.7419 | 4 | no |
| GO:0060341 | regulation of cellular localization | 27.0968 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.4516 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.4516 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 26.4516 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.1613 | 7 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.1613 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.1613 | 6 | no |
| GO:0031399 | regulation of protein modification process | 25.1613 | 6 | no |
| GO:0032880 | regulation of protein localization | 25.1613 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 25.1613 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.1613 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.5161 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.2258 | 5 | yes |
| GO:0036211 | protein modification process | 23.2258 | 4 | no |
| GO:0043412 | macromolecule modification | 23.2258 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.2258 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.2258 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.5806 | 6 | yes |
| GO:0009894 | regulation of catabolic process | 22.5806 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 22.5806 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.5806 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 22.5806 | 4 | no |
| GO:0071310 | cellular response to organic substance | 22.5806 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.9355 | 6 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 21.9355 | 4 | no |
| GO:0071702 | organic substance transport | 21.9355 | 4 | no |
| GO:0071705 | nitrogen compound transport | 21.9355 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.9355 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.2903 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.2903 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.2903 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.2903 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.2903 | 6 | no |
| GO:0033043 | regulation of organelle organization | 21.2903 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 20.6452 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 20.6452 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 20.6452 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.6452 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 16.1290 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 12.2581 | 4 | yes |
| GO:0030155 | regulation of cell adhesion | 10.9677 | 4 | yes |
| GO:0006986 | response to unfolded protein | 7.7419 | 4 | yes |
| GO:0045785 | positive regulation of cell adhesion | 7.0968 | 5 | yes |
| GO:0051084 | de novo post-translational protein folding | 7.0968 | 4 | yes |
| GO:0051085 | chaperone cofactor-dependent protein refolding | 6.4516 | 4 | yes |
| GO:0002694 | regulation of leukocyte activation | 5.1613 | 4 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 5.1613 | 5 | yes |
| GO:0050865 | regulation of cell activation | 5.1613 | 4 | yes |
| GO:0051249 | regulation of lymphocyte activation | 4.5161 | 5 | yes |
| GO:0002696 | positive regulation of leukocyte activation | 3.8710 | 5 | yes |
| GO:0022409 | positive regulation of cell-cell adhesion | 3.8710 | 6 | yes |
| GO:0050863 | regulation of T cell activation | 3.8710 | 6 | yes |
| GO:0050867 | positive regulation of cell activation | 3.8710 | 5 | yes |
| GO:0051251 | positive regulation of lymphocyte activation | 3.8710 | 6 | yes |
| GO:0050870 | positive regulation of T cell activation | 3.2258 | 7 | yes |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 3.2258 | 6 | yes |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 3.2258 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| STK39_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP49_HUMAN | [view interactions] | Low throughput | no | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PHLA1_HUMAN | [view interactions] | Low throughput | no | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLRB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADDA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PA1B3_HUMAN | [view interactions] | Low throughput | no | no |
| PGK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZBT7B_HUMAN | [view interactions] | Low throughput | no | no |
| NMI_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| NADAP_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| PAR6B_HUMAN | [view interactions] | High throughput | no | no |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| CE295_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| RPAP3_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| RRAGC_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| VTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| DPOE3_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CHMP5_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| MBD2_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| NRBP_HUMAN | [view interactions] | High throughput | no | yes |
| GRWD1_HUMAN | [view interactions] | High throughput | no | no |
| PSD13_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| RBGP1_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL5_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| BIG1_HUMAN | [view interactions] | High throughput | no | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCND1_HUMAN | [view interactions] | High throughput | no | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| TF3B_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| F16P1_HUMAN | [view interactions] | High throughput | no | no |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| GRB7_HUMAN | [view interactions] | High throughput | no | no |
| DNJB5_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| JMJD6_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZEB1_HUMAN | [view interactions] | High throughput | no | yes |
| ATG9A_HUMAN | [view interactions] | High throughput | no | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC9_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAM1_HUMAN | [view interactions] | High throughput | no | yes |
| RM47_HUMAN | [view interactions] | High throughput | no | yes |
| HS71L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSDE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| ARMC5_HUMAN | [view interactions] | High throughput | no | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| PR15A_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| BUB1B_HUMAN | [view interactions] | High throughput | no | no |
| MIS12_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD9_HUMAN | [view interactions] | High throughput | no | no |
| DNJB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| XPOT_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANO3_HUMAN | [view interactions] | High throughput | no | yes |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TUSC2_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| ZNFX1_HUMAN | [view interactions] | High throughput | no | yes |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| IF2G_HUMAN | [view interactions] | High throughput | no | yes |
| INKA2_HUMAN | [view interactions] | High throughput | no | yes |
| T11L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRSK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUXG_HUMAN | [view interactions] | High throughput | no | yes |
| BRSK2_HUMAN | [view interactions] | High throughput | no | no |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| USP9Y_HUMAN | [view interactions] | High throughput | no | no |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| DNJB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTK_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCSP_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| FND3A_HUMAN | [view interactions] | High throughput | no | yes |
| MTA70_HUMAN | [view interactions] | High throughput | no | no |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR35_HUMAN | [view interactions] | High throughput | no | no |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| BMX_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3G3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELK1_HUMAN | [view interactions] | High throughput | no | yes |
| FND3B_HUMAN | [view interactions] | High throughput | no | no |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIRP3_HUMAN | [view interactions] | High throughput | no | no |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PARVA_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| PUS7_HUMAN | [view interactions] | High throughput | no | yes |
| PEBB_HUMAN | [view interactions] | High throughput | no | no |
| SAMH1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF79_HUMAN | [view interactions] | High throughput | no | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZKSC3_HUMAN | [view interactions] | High throughput | no | yes |
| SET_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF3_HUMAN | [view interactions] | High throughput | no | yes |
| UGPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN283_HUMAN | [view interactions] | High throughput | no | no |
| ANM3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN614_HUMAN | [view interactions] | High throughput | no | no |
| RANB3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN304_HUMAN | [view interactions] | High throughput | no | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| ZN546_HUMAN | [view interactions] | High throughput | no | no |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAB2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA4_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC3_HUMAN | [view interactions] | High throughput | no | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| CPSM_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| DJC17_HUMAN | [view interactions] | High throughput | no | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| PPE1_HUMAN | [view interactions] | High throughput | no | no |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHLP2_HUMAN | [view interactions] | High throughput | no | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPCE_HUMAN | [view interactions] | High throughput | no | yes |
| BCL3_HUMAN | [view interactions] | High throughput | no | yes |
| PSB5_HUMAN | [view interactions] | High throughput | no | yes |
| COMD3_HUMAN | [view interactions] | High throughput | no | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPSE_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CGAS_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCF1_HUMAN | [view interactions] | High throughput | no | no |
| UBP39_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| CREB1_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV2_HUMAN | [view interactions] | High throughput | no | yes |
| HNF1A_HUMAN | [view interactions] | High throughput | no | no |
| ELAV3_HUMAN | [view interactions] | High throughput | no | yes |
| GLI2_HUMAN | [view interactions] | High throughput | no | yes |
| RT4I1_HUMAN | [view interactions] | High throughput | no | yes |
| CPEB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SELO_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| PSD11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD12_HUMAN | [view interactions] | High throughput | no | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAT1_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX15_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JIP4_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| ATG7_HUMAN | [view interactions] | High throughput | no | yes |
| M3K1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI16_HUMAN | [view interactions] | High throughput | no | no |
| IF4E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RTF1_HUMAN | [view interactions] | High throughput | no | yes |
| H14_HUMAN | [view interactions] | High throughput | no | yes |
| AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP13_HUMAN | [view interactions] | High throughput | no | yes |
| GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PYRG1_HUMAN | [view interactions] | High throughput | no | no |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE104_HUMAN | [view interactions] | High throughput | no | yes |
| ML12A_HUMAN | [view interactions] | High throughput | no | no |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA8_HUMAN | [view interactions] | High throughput | no | no |
| RAE1_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| MCM3_HUMAN | [view interactions] | High throughput | no | no |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| S10A2_HUMAN | [view interactions] | High throughput | no | no |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| HEM6_HUMAN | [view interactions] | High throughput | no | no |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| PRS6B_HUMAN | [view interactions] | High throughput | no | yes |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BLNK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYCC_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| PRI1_HUMAN | [view interactions] | High throughput | no | no |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSMD7_HUMAN | [view interactions] | High throughput | no | yes |
| NOS2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MT21A_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPSY_HUMAN | [view interactions] | High throughput | no | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PRS8_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| PRS10_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| 2ABA_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF3_HUMAN | [view interactions] | High throughput | no | yes |
| PLD1_HUMAN | [view interactions] | High throughput | no | no |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAZ1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BUB3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| KLC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| GOGA3_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFAC2_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN207_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA4_HUMAN | [view interactions] | High throughput | no | yes |
| EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
| ASAH1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| ZN638_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAPD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPOD1_HUMAN | [view interactions] | High throughput | no | yes |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| ELOB_HUMAN | [view interactions] | High throughput | no | no |
| TGFB1_HUMAN | [view interactions] | High throughput | no | no |
| CNN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADRM1_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDCD4_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR44_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| RMD5A_HUMAN | [view interactions] | High throughput | no | yes |
| 5MP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| UB2Q1_HUMAN | [view interactions] | High throughput | no | no |
| PTN7_HUMAN | [view interactions] | High throughput | no | no |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| RAD50_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| TOPK_HUMAN | [view interactions] | High throughput | no | no |