Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PYR1_HUMAN

This protein is a fusion protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in PYR1_HUMAN
GO:0000166 nucleotide binding 44.8819 4 yes
GO:0017076 purine nucleotide binding 44.8819 5 yes
GO:0032555 purine ribonucleotide binding 44.0945 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 44.0945 4 yes
GO:0043168 anion binding 44.0945 4 yes
GO:0030554 adenyl nucleotide binding 37.7953 6 yes
GO:0005524 ATP binding 37.0079 5 yes
GO:0032559 adenyl ribonucleotide binding 37.0079 5 yes
GO:0043169 cation binding 25.1969 4 yes
GO:0046872 metal ion binding 25.1969 5 yes
GO:0003723 RNA binding 24.4094 4 no
GO:0019900 kinase binding 22.8346 4 no
GO:0019901 protein kinase binding 21.2598 5 no
GO:0016301 kinase activity 16.5354 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 16.5354 4 yes
GO:0046914 transition metal ion binding 5.5118 6 yes
GO:0008270 zinc ion binding 3.9370 7 yes
GO:0031406 carboxylic acid binding 2.3622 4 yes
GO:0004070 aspartate carbamoyltransferase activity 1.5748 5 yes
GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 1.5748 5 yes
GO:0004151 dihydroorotase activity 1.5748 5 yes
GO:0016743 carboxyl- or carbamoyltransferase activity 1.5748 4 yes
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1.5748 4 yes
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1.5748 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PYR1_HUMAN
GO:0060255 regulation of macromolecule metabolic process 65.3543 4 no
GO:0080090 regulation of primary metabolic process 62.2047 4 no
GO:0031323 regulation of cellular metabolic process 60.6299 4 no
GO:0048522 positive regulation of cellular process 59.8425 4 no
GO:0009889 regulation of biosynthetic process 49.6063 4 no
GO:0031326 regulation of cellular biosynthetic process 48.8189 5 no
GO:0048523 negative regulation of cellular process 48.8189 4 no
GO:0009893 positive regulation of metabolic process 47.2441 4 no
GO:0051128 regulation of cellular component organization 47.2441 4 no
GO:0010556 regulation of macromolecule biosynthetic process 47.2441 5 no
GO:0051246 regulation of protein metabolic process 46.4567 5 no
GO:0010646 regulation of cell communication 45.6693 4 no
GO:0010604 positive regulation of macromolecule metabolic process 42.5197 5 no
GO:0010468 regulation of gene expression 41.7323 6 no
GO:0009966 regulation of signal transduction 40.9449 4 no
GO:0031325 positive regulation of cellular metabolic process 40.1575 5 no
GO:0006996 organelle organization 38.5827 4 no
GO:1902531 regulation of intracellular signal transduction 34.6457 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 34.6457 5 no
GO:0031399 regulation of protein modification process 33.8583 6 no
GO:0048584 positive regulation of response to stimulus 33.8583 4 no
GO:0009892 negative regulation of metabolic process 33.0709 4 no
GO:0022607 cellular component assembly 32.2835 4 no
GO:0051247 positive regulation of protein metabolic process 32.2835 6 no
GO:0010647 positive regulation of cell communication 30.7087 5 no
GO:0023056 positive regulation of signaling 30.7087 4 no
GO:0009891 positive regulation of biosynthetic process 30.7087 5 no
GO:0010605 negative regulation of macromolecule metabolic process 30.7087 5 no
GO:0019220 regulation of phosphate metabolic process 29.9213 6 no
GO:0051174 regulation of phosphorus metabolic process 29.9213 5 no
GO:0031328 positive regulation of cellular biosynthetic process 29.9213 6 no
GO:0048585 negative regulation of response to stimulus 29.1339 4 no
GO:0009967 positive regulation of signal transduction 28.3465 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 28.3465 6 no
GO:0031324 negative regulation of cellular metabolic process 28.3465 5 no
GO:0009894 regulation of catabolic process 27.5591 4 no
GO:0010648 negative regulation of cell communication 27.5591 5 no
GO:0023057 negative regulation of signaling 27.5591 4 no
GO:0051130 positive regulation of cellular component organization 27.5591 5 no
GO:0044087 regulation of cellular component biogenesis 27.5591 4 no
GO:0036211 protein modification process 26.7717 4 yes
GO:0043412 macromolecule modification 26.7717 4 yes
GO:0009968 negative regulation of signal transduction 26.7717 5 no
GO:0033043 regulation of organelle organization 26.7717 5 no
GO:0051252 regulation of RNA metabolic process 26.7717 5 no
GO:0008104 protein localization 25.9843 4 no
GO:0042981 regulation of apoptotic process 25.9843 5 no
GO:0043067 regulation of programmed cell death 25.9843 4 no
GO:0051049 regulation of transport 25.1969 4 no
GO:0060341 regulation of cellular localization 25.1969 4 no
GO:0006796 phosphate-containing compound metabolic process 25.1969 4 yes
GO:0031401 positive regulation of protein modification process 24.4094 7 no
GO:0042325 regulation of phosphorylation 24.4094 7 no
GO:0007010 cytoskeleton organization 23.6220 5 no
GO:0071310 cellular response to organic substance 23.6220 4 no
GO:0006355 regulation of DNA-templated transcription 23.6220 7 no
GO:2001141 regulation of RNA biosynthetic process 23.6220 6 no
GO:0080134 regulation of response to stress 22.8346 4 no
GO:0009890 negative regulation of biosynthetic process 22.8346 5 no
GO:0032880 regulation of protein localization 22.8346 5 no
GO:0001932 regulation of protein phosphorylation 22.0472 7 no
GO:0031327 negative regulation of cellular biosynthetic process 22.0472 6 no
GO:0010243 response to organonitrogen compound 21.2598 4 yes
GO:1902533 positive regulation of intracellular signal transduction 21.2598 6 no
GO:0051240 positive regulation of multicellular organismal process 21.2598 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.2598 6 no
GO:0016310 phosphorylation 17.3228 5 yes
GO:0014070 response to organic cyclic compound 15.7480 4 yes
GO:0033993 response to lipid 14.1732 4 yes
GO:0006468 protein phosphorylation 12.5984 5 yes
GO:0071363 cellular response to growth factor stimulus 9.4488 4 yes
GO:0018193 peptidyl-amino acid modification 8.6614 5 yes
GO:0043434 response to peptide hormone 7.8740 4 yes
GO:0097305 response to alcohol 7.0866 4 yes
GO:0034654 nucleobase-containing compound biosynthetic process 6.2992 4 yes
GO:0043279 response to alkaloid 6.2992 5 yes
GO:0048545 response to steroid hormone 6.2992 4 yes
GO:1901362 organic cyclic compound biosynthetic process 6.2992 4 yes
GO:0019752 carboxylic acid metabolic process 5.5118 5 yes
GO:0032868 response to insulin 5.5118 5 yes
GO:0043436 oxoacid metabolic process 5.5118 4 yes
GO:0046777 protein autophosphorylation 5.5118 6 yes
GO:1901654 response to ketone 5.5118 4 yes
GO:0046903 secretion 4.7244 4 yes
GO:0048732 gland development 4.7244 4 yes
GO:1901566 organonitrogen compound biosynthetic process 4.7244 4 yes
GO:0006753 nucleoside phosphate metabolic process 4.7244 4 yes
GO:0007507 heart development 4.7244 4 yes
GO:0009117 nucleotide metabolic process 4.7244 5 yes
GO:0009199 ribonucleoside triphosphate metabolic process 3.9370 6 yes
GO:0009259 ribonucleotide metabolic process 3.9370 5 yes
GO:0019693 ribose phosphate metabolic process 3.9370 4 yes
GO:0031960 response to corticosteroid 3.9370 5 yes
GO:0009141 nucleoside triphosphate metabolic process 3.9370 5 yes
GO:0016053 organic acid biosynthetic process 3.1496 4 yes
GO:0033574 response to testosterone 3.1496 5 yes
GO:0046394 carboxylic acid biosynthetic process 3.1496 5 yes
GO:0051384 response to glucocorticoid 3.1496 6 yes
GO:0090407 organophosphate biosynthetic process 3.1496 4 yes
GO:0009185 ribonucleoside diphosphate metabolic process 2.3622 6 yes
GO:0014074 response to purine-containing compound 2.3622 5 yes
GO:0018107 peptidyl-threonine phosphorylation 2.3622 6 yes
GO:0018210 peptidyl-threonine modification 2.3622 6 yes
GO:0070849 response to epidermal growth factor 2.3622 4 yes
GO:0071364 cellular response to epidermal growth factor stimulus 2.3622 5 yes
GO:0001889 liver development 2.3622 5 yes
GO:0007589 body fluid secretion 2.3622 4 yes
GO:0009132 nucleoside diphosphate metabolic process 2.3622 5 yes
GO:0009156 ribonucleoside monophosphate biosynthetic process 1.5748 7 yes
GO:0009161 ribonucleoside monophosphate metabolic process 1.5748 6 yes
GO:0009165 nucleotide biosynthetic process 1.5748 6 yes
GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process 1.5748 7 yes
GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process 1.5748 8 yes
GO:0009188 ribonucleoside diphosphate biosynthetic process 1.5748 7 yes
GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process 1.5748 7 yes
GO:0009194 pyrimidine ribonucleoside diphosphate biosynthetic process 1.5748 8 yes
GO:0009201 ribonucleoside triphosphate biosynthetic process 1.5748 7 yes
GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process 1.5748 7 yes
GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process 1.5748 8 yes
GO:0009218 pyrimidine ribonucleotide metabolic process 1.5748 6 yes
GO:0009220 pyrimidine ribonucleotide biosynthetic process 1.5748 7 yes
GO:0009260 ribonucleotide biosynthetic process 1.5748 6 yes
GO:0014075 response to amine 1.5748 5 yes
GO:0019240 citrulline biosynthetic process 1.5748 6 yes
GO:0019856 pyrimidine nucleobase biosynthetic process 1.5748 6 yes
GO:0031000 response to caffeine 1.5748 6 yes
GO:0031100 animal organ regeneration 1.5748 4 yes
GO:0044205 de novo UMP biosynthetic process 1.5748 9 yes
GO:0046048 UDP metabolic process 1.5748 7 yes
GO:0046049 UMP metabolic process 1.5748 7 yes
GO:0046051 UTP metabolic process 1.5748 7 yes
GO:0046112 nucleobase biosynthetic process 1.5748 5 yes
GO:0046390 ribose phosphate biosynthetic process 1.5748 5 yes
GO:0051414 response to cortisol 1.5748 5 yes
GO:0072527 pyrimidine-containing compound metabolic process 1.5748 4 yes
GO:0072528 pyrimidine-containing compound biosynthetic process 1.5748 5 yes
GO:0170033 L-amino acid metabolic process 1.5748 5 yes
GO:0170039 proteinogenic amino acid metabolic process 1.5748 4 yes
GO:0170041 non-proteinogenic amino acid metabolic process 1.5748 4 yes
GO:0170043 non-proteinogenic amino acid biosynthetic process 1.5748 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 1.5748 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 1.5748 5 yes
GO:1901605 alpha-amino acid metabolic process 1.5748 4 yes
GO:1901607 alpha-amino acid biosynthetic process 1.5748 5 yes
GO:0000052 citrulline metabolic process 1.5748 5 yes
GO:0006206 pyrimidine nucleobase metabolic process 1.5748 5 yes
GO:0006207 de novo pyrimidine nucleobase biosynthetic process 1.5748 7 yes
GO:0006220 pyrimidine nucleotide metabolic process 1.5748 5 yes
GO:0006221 pyrimidine nucleotide biosynthetic process 1.5748 6 yes
GO:0006222 UMP biosynthetic process 1.5748 8 yes
GO:0006225 UDP biosynthetic process 1.5748 8 yes
GO:0006228 UTP biosynthetic process 1.5748 8 yes
GO:0006541 glutamine metabolic process 1.5748 6 yes
GO:0007595 lactation 1.5748 5 yes
GO:0008652 amino acid biosynthetic process 1.5748 4 yes
GO:0009064 glutamine family amino acid metabolic process 1.5748 5 yes
GO:0009112 nucleobase metabolic process 1.5748 4 yes
GO:0009123 nucleoside monophosphate metabolic process 1.5748 5 yes
GO:0009124 nucleoside monophosphate biosynthetic process 1.5748 6 yes
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.5748 6 yes
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1.5748 7 yes
GO:0009133 nucleoside diphosphate biosynthetic process 1.5748 6 yes
GO:0009138 pyrimidine nucleoside diphosphate metabolic process 1.5748 6 yes
GO:0009139 pyrimidine nucleoside diphosphate biosynthetic process 1.5748 7 yes
GO:0009142 nucleoside triphosphate biosynthetic process 1.5748 6 yes
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 1.5748 6 yes
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 1.5748 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PYR1_HUMAN [view entry] [view interactions] Low throughput yes yes
RAD9A_HUMAN [view interactions] Low throughput no yes
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
SP1_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
SYDC_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
PYC_HUMAN [view entry] [view interactions] High throughput yes yes
HSC20_HUMAN [view interactions] High throughput no yes
SYSC_HUMAN [view interactions] High throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
MYOME_HUMAN [view interactions] High throughput no no
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
MET_HUMAN [view interactions] High throughput no yes
COPB_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
CNTRB_HUMAN [view interactions] High throughput no yes
DNJA4_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
EI2BA_HUMAN [view interactions] High throughput no yes
IKBE_HUMAN [view entry] [view interactions] High throughput yes yes
IF2A_HUMAN [view entry] [view interactions] High throughput yes yes
NEMO_HUMAN [view interactions] High throughput no yes
SYEP_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] High throughput no yes
GFPT1_HUMAN [view interactions] High throughput no no
M3K3_HUMAN [view interactions] High throughput no no
SYIC_HUMAN [view interactions] High throughput no yes
NFKB2_HUMAN [view interactions] High throughput no yes
IDH3A_HUMAN [view entry] [view interactions] High throughput yes yes
RELB_HUMAN [view interactions] High throughput no yes
IPO4_HUMAN [view interactions] High throughput no no
RIPK1_HUMAN [view interactions] High throughput no yes
MCM7_HUMAN [view interactions] High throughput no no
RIPK3_HUMAN [view interactions] High throughput no no
PRS6A_HUMAN [view entry] [view interactions] High throughput yes yes
TAB2_HUMAN [view interactions] High throughput no yes
PRS6B_HUMAN [view interactions] High throughput no yes
TNR1A_HUMAN [view interactions] High throughput no yes
PRS8_HUMAN [view interactions] High throughput no yes
TNR1B_HUMAN [view interactions] High throughput no no
PRS10_HUMAN [view interactions] High throughput no yes
TRADD_HUMAN [view interactions] High throughput no yes
PSD12_HUMAN [view interactions] High throughput no yes
TRAF2_HUMAN [view interactions] High throughput no yes
PSMD2_HUMAN [view entry] [view interactions] High throughput yes yes
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD4_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
S25A3_HUMAN [view entry] [view interactions] High throughput yes no
P5F1B_HUMAN [view interactions] High throughput no no
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
PO5F1_HUMAN [view interactions] High throughput no yes
YMEL1_HUMAN [view interactions] High throughput no yes
5HT7R_HUMAN [view entry] [view interactions] High throughput yes yes
PSD11_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
PSMD3_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
JIP4_HUMAN [view interactions] High throughput no yes
KATIP_HUMAN [view interactions] High throughput no yes
SMC2_HUMAN [view interactions] High throughput no yes
MKS1_HUMAN [view interactions] High throughput no no
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
AHI1_HUMAN [view interactions] High throughput no yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
POC1B_HUMAN [view interactions] High throughput no no
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC5_HUMAN [view interactions] High throughput no yes
RINI_HUMAN [view interactions] High throughput no yes
NCOA2_HUMAN [view interactions] High throughput no no
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
RAD21_HUMAN [view interactions] High throughput no yes
GNS_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
TGM2_HUMAN [view interactions] High throughput no no
ERG_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
FBX25_HUMAN [view interactions] High throughput no no
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
CDK2_HUMAN [view interactions] High throughput no yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
CBL_HUMAN [view interactions] High throughput no yes
LPPRC_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
RS10_HUMAN [view entry] [view interactions] High throughput yes yes
FOXP3_HUMAN [view interactions] High throughput no no
TAF6_HUMAN [view interactions] High throughput no no
IQCB1_HUMAN [view interactions] High throughput no no
PSMD7_HUMAN [view interactions] High throughput no yes
NOS2_HUMAN [view interactions] High throughput no yes
PP1B_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
SMD2_HUMAN [view interactions] High throughput no yes
WWOX_HUMAN [view interactions] High throughput no yes
PI42B_HUMAN [view entry] [view interactions] High throughput yes no
LGR4_HUMAN [view interactions] High throughput no yes
IF4G1_HUMAN [view entry] [view interactions] High throughput yes yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
UBE3A_HUMAN [view entry] [view interactions] High throughput yes yes
SPRTN_HUMAN [view interactions] High throughput no yes
GOGA4_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
ASAH1_HUMAN [view interactions] High throughput no yes
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
GAPD1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
PSMD6_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
ADRM1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
GGYF2_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
SKI_HUMAN [view interactions] High throughput no yes
PSB7_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
VTA1_HUMAN [view entry] [view interactions] High throughput yes yes
KSR1_HUMAN [view interactions] High throughput no yes
CPSF2_HUMAN [view entry] [view interactions] High throughput yes yes
CAF1A_HUMAN [view interactions] High throughput no yes
MBD2_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
SAE2_HUMAN [view interactions] High throughput no yes
NFAC1_HUMAN [view interactions] High throughput no no
PRP19_HUMAN [view interactions] High throughput no yes
NFAC2_HUMAN [view interactions] High throughput no yes
PSD13_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
DERL1_HUMAN [view interactions] High throughput no yes
NHLC2_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
HAX1_HUMAN [view interactions] High throughput no no
MTMRB_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
DYR2_HUMAN [view interactions] High throughput no yes
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
VHL_HUMAN [view entry] [view interactions] High throughput yes yes
K1C18_HUMAN [view interactions] High throughput no no
FAS_HUMAN [view entry] [view interactions] High throughput yes no
K2C8_HUMAN [view interactions] High throughput no no
BRCA1_HUMAN [view interactions] High throughput no yes
NFM_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
RPB3_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
TEDC2_HUMAN [view interactions] High throughput no no
NBR1_HUMAN [view interactions] High throughput no yes
ZUP1_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
FBX7_HUMAN [view interactions] High throughput no yes
COP1_HUMAN [view interactions] High throughput no no
BMR1A_HUMAN [view interactions] High throughput no no
SMU1_HUMAN [view interactions] High throughput no yes
ACON_HUMAN [view entry] [view interactions] High throughput yes yes
RFA1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
KC1A_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
DX39B_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
SYLC_HUMAN [view interactions] High throughput no yes
DPOD1_HUMAN [view interactions] High throughput no yes
PPP6_HUMAN [view interactions] High throughput no yes
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
B2CL1_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
TGFB1_HUMAN [view interactions] High throughput no no
TRIP4_HUMAN [view interactions] High throughput no yes
HIF1N_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
LAP2A_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
RNF31_HUMAN [view interactions] High throughput no yes
UB2R1_HUMAN [view interactions] High throughput no yes
SPDLY_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
HERC2_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
GLP1R_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
CCND1_HUMAN [view interactions] High throughput no yes
TM41B_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
HDAC2_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
S15A3_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
EWS_HUMAN [view interactions] High throughput no yes
MATR3_HUMAN [view interactions] High throughput no yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
ARAF_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
BRD7_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
FBXW8_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
LRC31_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
AIMP2_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
CIC_HUMAN [view interactions] High throughput no yes
2ABB_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
P63_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
WDR76_HUMAN [view interactions] High throughput no no
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
UBP10_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
ASXL1_HUMAN [view interactions] High throughput no no
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
UNKL_HUMAN [view interactions] High throughput no no
NPHP1_HUMAN [view interactions] High throughput no yes
ISG15_HUMAN [view interactions] High throughput no no
FTM_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
LRFN4_HUMAN [view entry] [view interactions] High throughput yes yes
UFL1_HUMAN [view interactions] High throughput no yes
HDA11_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
MK06_HUMAN [view interactions] High throughput no yes
PAGE4_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
TBX19_HUMAN [view interactions] High throughput no no
ILK_HUMAN [view interactions] High throughput no no
VWA2_HUMAN [view interactions] High throughput no no
OTUB1_HUMAN [view interactions] High throughput no yes
I12R1_HUMAN [view interactions] High throughput no no
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
TBB5_HUMAN [view interactions] High throughput no yes
GET4_HUMAN [view interactions] High throughput no yes
LOXL4_HUMAN [view interactions] High throughput no no
SC16A_HUMAN [view interactions] High throughput no yes
UBP11_HUMAN [view interactions] High throughput no yes
LG3BP_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
DNJC7_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
TRI29_HUMAN [view interactions] High throughput no no
SIR6_HUMAN [view interactions] High throughput no yes
TBA1C_HUMAN [view interactions] High throughput no yes
ZEB1_HUMAN [view interactions] High throughput no yes
MD2L1_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
RHBT1_HUMAN [view interactions] High throughput no yes
ADIP_HUMAN [view interactions] High throughput no yes
RHBT2_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
RRP1B_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
MTA70_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
PRD16_HUMAN [view interactions] High throughput no no
FKBP5_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
HMGN5_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
MIF_HUMAN [view entry] [view interactions] High throughput yes yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
MRT4_HUMAN [view interactions] High throughput no yes
VAV_HUMAN [view interactions] High throughput no no
TEBP_HUMAN [view interactions] High throughput no yes
SH3L1_HUMAN [view interactions] High throughput no yes
TRI31_HUMAN [view interactions] High throughput no no
FGR_HUMAN [view interactions] High throughput no no
ANM1_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
SHCAF_HUMAN [view interactions] High throughput no yes
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
MYCN_HUMAN [view interactions] High throughput no no
KPCE_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
BAD_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
ELK1_HUMAN [view interactions] High throughput no yes
ARMC5_HUMAN [view interactions] High throughput no yes
PAK1_HUMAN [view entry] [view interactions] High throughput yes yes
LATS1_HUMAN [view entry] [view interactions] High throughput yes yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC1_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
LOXL2_HUMAN [view interactions] High throughput no yes
SRC_HUMAN [view entry] [view interactions] High throughput yes no
R113A_HUMAN [view interactions] High throughput no yes
DUS4_HUMAN [view entry] [view interactions] High throughput yes no
ACE2_HUMAN [view interactions] High throughput no no
MK07_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
CSK_HUMAN [view interactions] High throughput no yes
GBRA1_HUMAN [view entry] [view interactions] High throughput yes yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
M3K14_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RUFY1_HUMAN [view interactions] High throughput no yes
GRB10_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
MP2K1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI33_HUMAN [view interactions] High throughput no yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP2_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
RIN3_HUMAN [view interactions] High throughput no yes
ASXL2_HUMAN [view interactions] High throughput no no
SOX2_HUMAN [view interactions] High throughput no yes
RHG24_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
SRS10_HUMAN [view interactions] High throughput no yes
RMC1_HUMAN [view interactions] High throughput no no
GCSP_HUMAN [view interactions] High throughput no yes
SIM26_HUMAN [view interactions] High throughput no no
MOB3C_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
MEX3C_HUMAN [view interactions] High throughput no yes
GRM2_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA2_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
OTUD1_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
UBP36_HUMAN [view interactions] High throughput no yes
PPE1_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
PPP5_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP1_HUMAN [view interactions] High throughput no yes
DUS16_HUMAN [view interactions] High throughput no yes
RN138_HUMAN [view entry] [view interactions] High throughput yes no
PTN23_HUMAN [view entry] [view interactions] High throughput yes yes
FITM2_HUMAN [view interactions] High throughput no no
SNF5_HUMAN [view interactions] High throughput no yes
ATG12_HUMAN [view interactions] High throughput no yes
B2L14_HUMAN [view interactions] High throughput no yes
SPRNG_HUMAN [view interactions] High throughput no yes
IRF7_HUMAN [view interactions] High throughput no yes
ATG7_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
MP2K7_HUMAN [view entry] [view interactions] High throughput yes yes
RIT1_HUMAN [view interactions] High throughput no yes
GRK6_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view entry] [view interactions] High throughput yes yes
IRAK1_HUMAN [view interactions] High throughput no yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
PRKX_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
LIMK1_HUMAN [view entry] [view interactions] High throughput yes yes
XIAP_HUMAN [view interactions] High throughput no yes
LIMK2_HUMAN [view interactions] High throughput no yes
HTRA2_HUMAN [view interactions] High throughput no yes
PDK4_HUMAN [view interactions] High throughput no yes
RUVB2_HUMAN [view interactions] High throughput no yes
PKN3_HUMAN [view interactions] High throughput no yes
TBB4B_HUMAN [view interactions] High throughput no yes
ST32C_HUMAN [view entry] [view interactions] High throughput yes yes
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
CDK20_HUMAN [view interactions] High throughput no yes
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
COQ8A_HUMAN [view interactions] High throughput no no
RUVB1_HUMAN [view interactions] High throughput no yes
M4K1_HUMAN [view interactions] High throughput no no
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
TESK2_HUMAN [view interactions] High throughput no yes
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
TSSK6_HUMAN [view interactions] High throughput no no
SMRC2_HUMAN [view interactions] High throughput no yes
STK33_HUMAN [view interactions] High throughput no no
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
PAK6_HUMAN [view entry] [view interactions] High throughput yes yes
PRS7_HUMAN [view interactions] High throughput no yes
LATS2_HUMAN [view interactions] High throughput no yes
SMCA4_HUMAN [view interactions] High throughput no yes
NRBP2_HUMAN [view interactions] High throughput no yes
SYVC_HUMAN [view interactions] High throughput no yes
TBXT_HUMAN [view interactions] High throughput no no
ACTZ_HUMAN [view entry] [view interactions] High throughput yes yes
SP7_HUMAN [view interactions] High throughput no no
ACSA_HUMAN [view interactions] High throughput no no