Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ACTZ_HUMAN

Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ACTZ_HUMAN
GO:0017076 purine nucleotide binding 37.9310 4 yes
GO:0032555 purine ribonucleotide binding 37.9310 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 37.9310 4 yes
GO:0005524 ATP binding 34.4828 5 yes
GO:0030554 adenyl nucleotide binding 34.4828 5 yes
GO:0032559 adenyl ribonucleotide binding 34.4828 5 yes
GO:0003723 RNA binding 24.1379 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in ACTZ_HUMAN
GO:0048522 positive regulation of cellular process 55.1724 4 no
GO:0051128 regulation of cellular component organization 54.0230 4 no
GO:0060255 regulation of macromolecule metabolic process 45.9770 4 no
GO:0006996 organelle organization 45.9770 4 no
GO:0051171 regulation of nitrogen compound metabolic process 44.8276 4 no
GO:0031323 regulation of cellular metabolic process 43.6782 4 no
GO:0080090 regulation of primary metabolic process 43.6782 4 no
GO:0022607 cellular component assembly 42.5287 4 no
GO:0048523 negative regulation of cellular process 41.3793 4 no
GO:0033043 regulation of organelle organization 41.3793 5 no
GO:0009893 positive regulation of metabolic process 35.6322 4 no
GO:0008104 protein localization 34.4828 4 no
GO:0044087 regulation of cellular component biogenesis 33.3333 4 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 32.1839 5 no
GO:0007010 cytoskeleton organization 29.8851 5 no
GO:0009889 regulation of biosynthetic process 28.7356 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.7356 5 no
GO:0031325 positive regulation of cellular metabolic process 28.7356 5 no
GO:0031326 regulation of cellular biosynthetic process 28.7356 5 no
GO:0010646 regulation of cell communication 28.7356 4 no
GO:0010556 regulation of macromolecule biosynthetic process 27.5862 5 no
GO:0051246 regulation of protein metabolic process 27.5862 5 no
GO:0010638 positive regulation of organelle organization 26.4368 6 no
GO:0060341 regulation of cellular localization 25.2874 4 no
GO:0051049 regulation of transport 25.2874 4 no
GO:0043933 protein-containing complex organization 24.1379 4 no
GO:0009966 regulation of signal transduction 24.1379 4 no
GO:0071702 organic substance transport 24.1379 4 no
GO:0071705 nitrogen compound transport 24.1379 4 no
GO:0009892 negative regulation of metabolic process 24.1379 4 no
GO:0009891 positive regulation of biosynthetic process 22.9885 5 no
GO:0031328 positive regulation of cellular biosynthetic process 22.9885 6 no
GO:0032880 regulation of protein localization 22.9885 5 no
GO:0010468 regulation of gene expression 22.9885 5 no
GO:0031399 regulation of protein modification process 22.9885 6 no
GO:0051493 regulation of cytoskeleton organization 21.8391 6 no
GO:0048584 positive regulation of response to stimulus 21.8391 4 no
GO:0043254 regulation of protein-containing complex assembly 20.6897 5 no
GO:0051129 negative regulation of cellular component organization 20.6897 5 no
GO:0010647 positive regulation of cell communication 20.6897 5 no
GO:0019220 regulation of phosphate metabolic process 20.6897 6 no
GO:0023056 positive regulation of signaling 20.6897 4 no
GO:0051174 regulation of phosphorus metabolic process 20.6897 5 no
GO:0010605 negative regulation of macromolecule metabolic process 20.6897 5 no
GO:0031324 negative regulation of cellular metabolic process 20.6897 5 no
GO:0016192 vesicle-mediated transport 17.2414 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in ACTZ_HUMAN
DOID:331 central nervous system disease 2.2989 3 no
DOID:37 skin disease 2.2989 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DCTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
BICD2_HUMAN [view interactions] Low throughput no yes
ARP10_HUMAN [view interactions] Low throughput no no
SPTN2_HUMAN [view entry] [view interactions] Low throughput yes yes
NUMA1_HUMAN [view interactions] Low throughput no yes
HDAC6_HUMAN [view interactions] Low throughput no yes
BCL2_HUMAN [view interactions] Low throughput no no
ACTB_HUMAN [view entry] [view interactions] Low throughput yes no
PRS6B_HUMAN [view interactions] High throughput no yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
PSMD1_HUMAN [view entry] [view interactions] High throughput yes yes
RRS1_HUMAN [view interactions] High throughput no yes
MCM7_HUMAN [view interactions] High throughput no no
COG3_HUMAN [view entry] [view interactions] High throughput yes yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
MYCBP_HUMAN [view interactions] High throughput no yes
NU133_HUMAN [view interactions] High throughput no yes
ACDSB_HUMAN [view interactions] High throughput no yes
PYR1_HUMAN [view entry] [view interactions] High throughput yes yes
CCAR1_HUMAN [view interactions] High throughput no yes
CDC45_HUMAN [view interactions] High throughput no no
IMA4_HUMAN [view interactions] High throughput no yes
IMA3_HUMAN [view interactions] High throughput no yes
SF3A1_HUMAN [view interactions] High throughput no yes
SF3A3_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
ZW10_HUMAN [view interactions] High throughput no yes
PACN3_HUMAN [view interactions] High throughput no yes
RPB4_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
DC1I1_HUMAN [view entry] [view interactions] High throughput yes yes
NECD_HUMAN [view interactions] High throughput no no
ALMS1_HUMAN [view interactions] High throughput no no
BCR_HUMAN [view entry] [view interactions] High throughput yes yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
CDC37_HUMAN [view interactions] High throughput no yes
CIP2A_HUMAN [view interactions] High throughput no yes
COMD8_HUMAN [view interactions] High throughput no yes
DEN5A_HUMAN [view interactions] High throughput no yes
DEN5B_HUMAN [view interactions] High throughput no yes
DYH10_HUMAN [view interactions] High throughput no no
FKBP4_HUMAN [view entry] [view interactions] High throughput yes yes
GLMN_HUMAN [view interactions] High throughput no no
HOOK1_HUMAN [view interactions] High throughput no no
NUDC_HUMAN [view interactions] High throughput no yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC3_HUMAN [view interactions] High throughput no yes
PFD2_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
PFD6_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
PP4R1_HUMAN [view interactions] High throughput no yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
RPAP3_HUMAN [view interactions] High throughput no yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
SCFD1_HUMAN [view entry] [view interactions] High throughput yes yes
SSH2_HUMAN [view interactions] High throughput no no
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
SGT1_HUMAN [view interactions] High throughput no no
TTC4_HUMAN [view interactions] High throughput no yes
TWF1_HUMAN [view entry] [view interactions] High throughput yes no
TWF2_HUMAN [view interactions] High throughput no no
TXNL1_HUMAN [view entry] [view interactions] High throughput yes yes
PFD3_HUMAN [view interactions] High throughput no yes
VEZA_HUMAN [view interactions] High throughput no yes
ARFG2_HUMAN [view entry] [view interactions] High throughput yes yes
CA198_HUMAN [view interactions] High throughput no yes
C170B_HUMAN [view interactions] High throughput no yes
DHCR7_HUMAN [view interactions] High throughput no yes
KBP_HUMAN [view interactions] High throughput no yes
TTC1_HUMAN [view interactions] High throughput no yes
TXND9_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
DCTN2_HUMAN [view entry] [view interactions] High throughput yes yes
DCTN3_HUMAN [view entry] [view interactions] High throughput yes yes
DC1L1_HUMAN [view entry] [view interactions] High throughput yes yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
DLRB1_HUMAN [view entry] [view interactions] High throughput yes no
ZC3H1_HUMAN [view interactions] High throughput no yes
NFYC_HUMAN [view interactions] High throughput no no
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ACTY_HUMAN [view entry] [view interactions] High throughput yes no
DCTN5_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
IWS1_HUMAN [view interactions] High throughput no yes
CAZA2_HUMAN [view entry] [view interactions] High throughput yes yes
DYHC1_HUMAN [view entry] [view interactions] High throughput yes yes
INAVA_HUMAN [view interactions] High throughput no yes
MERB1_HUMAN [view interactions] High throughput no yes
MS18A_HUMAN [view interactions] High throughput no yes
DB127_HUMAN [view interactions] High throughput no no
DCTN6_HUMAN [view interactions] High throughput no no
AAPK1_HUMAN [view interactions] High throughput no no
AAKB1_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
MOT11_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
PLEC_HUMAN [view entry] [view interactions] High throughput yes yes
AHNK2_HUMAN [view interactions] High throughput no yes
ECHP_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
SCRB2_HUMAN [view interactions] High throughput no yes
TIE1_HUMAN [view interactions] High throughput no no
HLAB_HUMAN [view interactions] High throughput no yes
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
SNW1_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
CAV3_HUMAN [view interactions] High throughput no no
TX101_HUMAN [view interactions] High throughput no no
ITM2B_HUMAN [view interactions] High throughput no yes
ANS1B_HUMAN [view entry] [view interactions] High throughput yes yes
ACTZ_HUMAN [view entry] [view interactions] High throughput yes yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
CEP76_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ESR2_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
NIN_HUMAN [view interactions] High throughput no no
MED4_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
SHIP1_HUMAN [view interactions] High throughput no no
SMUF1_HUMAN [view interactions] High throughput no yes
STB5L_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
KLHL2_HUMAN [view interactions] High throughput no no
RIC8A_HUMAN [view entry] [view interactions] High throughput yes no
PDGFD_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
G3BP1_HUMAN [view interactions] High throughput no yes
ZUP1_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
ZN598_HUMAN [view interactions] High throughput no no
UB2L6_HUMAN [view interactions] High throughput no no
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
RN181_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
ACTC_HUMAN [view interactions] High throughput no no
TRPV1_HUMAN [view entry] [view interactions] High throughput yes no
ATX1_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
NFX1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
ANLN_HUMAN [view interactions] High throughput no yes
AIMP2_HUMAN [view interactions] High throughput no yes
NINL_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
PD1L1_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
TCPW_HUMAN [view entry] [view interactions] High throughput yes yes
PDCL3_HUMAN [view interactions] High throughput no yes
GELS_HUMAN [view entry] [view interactions] High throughput yes no
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
ACTA_HUMAN [view interactions] High throughput no no
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
ARK72_HUMAN [view entry] [view interactions] High throughput yes yes
CPVL_HUMAN [view interactions] High throughput no no
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
F16P1_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
RBCC1_HUMAN [view interactions] High throughput no no
BAG1_HUMAN [view interactions] High throughput no yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
CLAP1_HUMAN [view entry] [view interactions] High throughput yes yes
CLAP2_HUMAN [view entry] [view interactions] High throughput yes no
CLIP1_HUMAN [view entry] [view interactions] High throughput yes yes
DC1I2_HUMAN [view entry] [view interactions] High throughput yes yes
DC1L2_HUMAN [view entry] [view interactions] High throughput yes yes
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
DYL2_HUMAN [view entry] [view interactions] High throughput yes no
TBB4B_HUMAN [view interactions] High throughput no yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
RIT1_HUMAN [view interactions] High throughput no yes
PRGR_HUMAN [view interactions] Computational no no
DYH9_HUMAN [view interactions] Computational no no
DYH14_HUMAN [view interactions] Computational no no
MYO1A_HUMAN [view interactions] Computational no no
DYH3_HUMAN [view interactions] Computational no no
DNAI2_HUMAN [view interactions] Computational no no
DYH6_HUMAN [view interactions] Computational no no
DYH17_HUMAN [view interactions] Computational no no
RAB18_HUMAN [view entry] [view interactions] Computational yes yes
DYH11_HUMAN [view interactions] Computational no no
DYH2_HUMAN [view interactions] Computational no no
GCR_HUMAN [view entry] [view interactions] Computational yes yes
RBGPR_HUMAN [view entry] [view interactions] Computational yes yes
MCR_HUMAN [view entry] [view interactions] Computational yes yes
LIS1_HUMAN [view entry] [view interactions] Computational yes yes
DYH1_HUMAN [view interactions] Computational no yes
RB3GP_HUMAN [view entry] [view interactions] Computational yes yes
HS90B_HUMAN [view entry] [view interactions] Computational yes yes
DNAL1_HUMAN [view interactions] Computational no no
HAP1_HUMAN [view entry] [view interactions] Computational yes yes
DNAL4_HUMAN [view interactions] Computational no yes
DYH12_HUMAN [view interactions] Computational no no
DYH7_HUMAN [view interactions] Computational no no
ANDR_HUMAN [view interactions] Computational no no
HS90A_HUMAN [view entry] [view interactions] Computational yes yes
DYH5_HUMAN [view interactions] Computational no no