TCPW_HUMAN
Evidence for PS localization
Functions
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TCPW_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 52.0833 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 52.0833 | 5 | yes |
| GO:0043168 | anion binding | 50.0000 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 47.9167 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 47.9167 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 35.4167 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 35.4167 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 35.4167 | 6 | yes |
| GO:0030554 | adenyl nucleotide binding | 35.4167 | 6 | yes |
| GO:0005524 | ATP binding | 31.2500 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 31.2500 | 5 | yes |
| GO:0043169 | cation binding | 25.0000 | 4 | no |
| GO:0046872 | metal ion binding | 25.0000 | 5 | no |
| GO:0003723 | RNA binding | 25.0000 | 4 | no |
| GO:0016887 | ATP hydrolysis activity | 18.7500 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TCPW_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 43.7500 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 39.5833 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 37.5000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 37.5000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 35.4167 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.4167 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 35.4167 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 31.2500 | 4 | no |
| GO:0032880 | regulation of protein localization | 29.1667 | 5 | no |
| GO:0060341 | regulation of cellular localization | 29.1667 | 4 | no |
| GO:0006996 | organelle organization | 29.1667 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.1667 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.1667 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 27.0833 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.0833 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | no |
| GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0070201 | regulation of establishment of protein localization | 25.0000 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.9167 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.9167 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.9167 | 6 | no |
| GO:0010638 | positive regulation of organelle organization | 22.9167 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.8333 | 5 | no |
| GO:0033044 | regulation of chromosome organization | 20.8333 | 6 | no |
| GO:1903829 | positive regulation of protein localization | 20.8333 | 5 | no |
| GO:0043933 | protein-containing complex organization | 20.8333 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| TRI68_HUMAN | [view interactions] | High throughput | no | yes |
| CDK10_HUMAN | [view interactions] | High throughput | no | no |
| KR194_HUMAN | [view interactions] | High throughput | no | no |
| TAF1C_HUMAN | [view interactions] | High throughput | no | no |
| DAZ2_HUMAN | [view interactions] | High throughput | no | no |
| FOH1B_HUMAN | [view interactions] | High throughput | no | no |
| DTL_HUMAN | [view interactions] | High throughput | no | no |
| PDCL3_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW9_HUMAN | [view interactions] | High throughput | no | yes |
| TLE2_HUMAN | [view interactions] | High throughput | no | yes |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| HPTR_HUMAN | [view interactions] | High throughput | no | no |
| PP4C_HUMAN | [view interactions] | High throughput | no | yes |
| ACTT1_HUMAN | [view interactions] | High throughput | no | no |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN5_HUMAN | [view interactions] | High throughput | no | yes |
| PGAM4_HUMAN | [view interactions] | High throughput | no | no |
| CBPC6_HUMAN | [view interactions] | High throughput | no | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GXLT2_HUMAN | [view interactions] | High throughput | no | no |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET27_HUMAN | [view interactions] | High throughput | no | yes |
| CAN10_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW5_HUMAN | [view interactions] | High throughput | no | no |
| RFPL1_HUMAN | [view interactions] | High throughput | no | no |
| MMAC_HUMAN | [view interactions] | High throughput | no | no |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GT253_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| MYH7B_HUMAN | [view interactions] | High throughput | no | no |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLH26_HUMAN | [view interactions] | High throughput | no | no |
| KR151_HUMAN | [view interactions] | High throughput | no | no |
| AP3M2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANGL7_HUMAN | [view interactions] | High throughput | no | no |
| RAB6C_HUMAN | [view interactions] | High throughput | no | no |
| DDB2_HUMAN | [view interactions] | High throughput | no | yes |
| TRM61_HUMAN | [view interactions] | High throughput | no | no |
| TCAB1_HUMAN | [view interactions] | High throughput | no | yes |
| PAG15_HUMAN | [view interactions] | High throughput | no | yes |
| FA83F_HUMAN | [view interactions] | High throughput | no | no |
| B4GT2_HUMAN | [view interactions] | High throughput | no | no |
| ACTT2_HUMAN | [view interactions] | High throughput | no | no |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIOX_HUMAN | [view interactions] | High throughput | no | no |
| PELI3_HUMAN | [view interactions] | High throughput | no | yes |
| ACMSD_HUMAN | [view interactions] | High throughput | no | no |
| HECD3_HUMAN | [view interactions] | High throughput | no | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LFNG_HUMAN | [view interactions] | High throughput | no | no |
| STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB1_HUMAN | [view interactions] | High throughput | no | yes |
| SCOT2_HUMAN | [view interactions] | High throughput | no | no |
| SUMF2_HUMAN | [view interactions] | High throughput | no | yes |
| LIRA5_HUMAN | [view interactions] | High throughput | no | no |
| ITPK1_HUMAN | [view interactions] | High throughput | no | yes |
| PL8L1_HUMAN | [view interactions] | High throughput | no | no |
| DC4L1_HUMAN | [view interactions] | High throughput | no | no |
| ADAM7_HUMAN | [view interactions] | High throughput | no | no |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACADM_HUMAN | [view interactions] | High throughput | no | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH2_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP27A_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA4_HUMAN | [view interactions] | High throughput | no | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| PRS7_HUMAN | [view interactions] | High throughput | no | yes |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| STK26_HUMAN | [view interactions] | High throughput | no | no |
| WDR59_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOCN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| DCAF8_HUMAN | [view interactions] | High throughput | no | yes |
| ACL6A_HUMAN | [view interactions] | High throughput | no | yes |
| DC2I2_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR83_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP1_HUMAN | [view interactions] | High throughput | no | no |
| KLD8A_HUMAN | [view interactions] | High throughput | no | no |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| FBXW4_HUMAN | [view interactions] | High throughput | no | no |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR86_HUMAN | [view interactions] | High throughput | no | no |
| TBG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCFC2_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF5_HUMAN | [view interactions] | High throughput | no | yes |
| DCA11_HUMAN | [view interactions] | High throughput | no | yes |
| TBL1Y_HUMAN | [view interactions] | High throughput | no | no |
| KLDC2_HUMAN | [view interactions] | High throughput | no | yes |
| THOC3_HUMAN | [view interactions] | High throughput | no | yes |
| RM38_HUMAN | [view interactions] | High throughput | no | yes |
| RAP2C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| KLH33_HUMAN | [view interactions] | High throughput | no | yes |
| PEX7_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5B_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL4_HUMAN | [view interactions] | High throughput | no | no |
| RPE65_HUMAN | [view interactions] | High throughput | no | no |
| TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
| LRC10_HUMAN | [view interactions] | High throughput | no | no |
| AICDA_HUMAN | [view interactions] | High throughput | no | no |
| STRAB_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI1_HUMAN | [view interactions] | High throughput | no | no |
| SPAG6_HUMAN | [view interactions] | High throughput | no | no |
| 2ABD_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW8_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3B_HUMAN | [view interactions] | High throughput | no | yes |
| F86B2_HUMAN | [view interactions] | High throughput | no | no |
| MET18_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| PLBL1_HUMAN | [view interactions] | High throughput | no | no |
| CF300_HUMAN | [view interactions] | High throughput | no | no |
| TXND9_HUMAN | [view interactions] | High throughput | no | yes |
| FYCO1_HUMAN | [view interactions] | High throughput | no | no |
| SMIP6_HUMAN | [view interactions] | High throughput | no | yes |
| WDR37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNSL2_HUMAN | [view interactions] | High throughput | no | no |
| DAA10_HUMAN | [view interactions] | High throughput | no | yes |
| LST8_HUMAN | [view interactions] | High throughput | no | yes |
| MPPD1_HUMAN | [view interactions] | High throughput | no | no |
| SEP12_HUMAN | [view interactions] | High throughput | no | no |
| MK10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNB5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTY_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICE2_HUMAN | [view interactions] | High throughput | no | no |
| SC31B_HUMAN | [view interactions] | High throughput | no | yes |
| DC4L2_HUMAN | [view interactions] | High throughput | no | no |
| TBAL3_HUMAN | [view interactions] | High throughput | no | no |
| TTLL1_HUMAN | [view interactions] | High throughput | no | yes |
| PLPL1_HUMAN | [view interactions] | High throughput | no | no |
| TTLL3_HUMAN | [view interactions] | High throughput | no | yes |
| SYFA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATB1_HUMAN | [view interactions] | High throughput | no | no |
| CDK15_HUMAN | [view interactions] | High throughput | no | no |
| GAN_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| BUB3_HUMAN | [view interactions] | High throughput | no | yes |
| DCA10_HUMAN | [view interactions] | High throughput | no | no |
| SMOX_HUMAN | [view interactions] | High throughput | no | yes |
| KDM4B_HUMAN | [view interactions] | High throughput | no | no |
| COP1_HUMAN | [view interactions] | High throughput | no | no |
| TTLL9_HUMAN | [view interactions] | High throughput | no | no |
| DNAI2_HUMAN | [view interactions] | High throughput | no | no |
| CD11A_HUMAN | [view interactions] | High throughput | no | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| PLB1_HUMAN | [view interactions] | High throughput | no | no |
| MK15_HUMAN | [view interactions] | High throughput | no | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| 2ABG_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS19_HUMAN | [view interactions] | High throughput | no | yes |
| DUS21_HUMAN | [view interactions] | High throughput | no | no |
| MTMR6_HUMAN | [view interactions] | High throughput | no | no |
| MTMR8_HUMAN | [view interactions] | High throughput | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| TBD_HUMAN | [view interactions] | High throughput | no | yes |
| VRTN_HUMAN | [view interactions] | High throughput | no | no |