WDR37_HUMAN
Interacting region for partners were not defined.
Position | Amino acid | Mutation | Disease | Overlap with binding region |
---|---|---|---|---|
119 | Ser | Phe | Neurooculocardiogenitourinarysyndrome(NOCGUS) | - |
125 | Thr | Ile | Neurooculocardiogenitourinarysyndrome(NOCGUS) | - |
129 | Ser | Cys | Neurooculocardiogenitourinarysyndrome(NOCGUS) | - |
130 | Thr | Ile | Neurooculocardiogenitourinarysyndrome(NOCGUS) | - |
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in WDR37_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 40.0000 | 4 | no |
GO:0003723 | RNA binding | 36.6667 | 4 | no |
GO:0019900 | kinase binding | 36.6667 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 36.6667 | 5 | no |
GO:0019901 | protein kinase binding | 33.3333 | 5 | no |
GO:0016462 | pyrophosphatase activity | 33.3333 | 5 | no |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 33.3333 | 4 | no |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 33.3333 | 6 | no |
GO:0032555 | purine ribonucleotide binding | 33.3333 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 33.3333 | 4 | no |
GO:0005524 | ATP binding | 30.0000 | 5 | no |
GO:0016887 | ATP hydrolysis activity | 30.0000 | 7 | no |
GO:0032559 | adenyl ribonucleotide binding | 30.0000 | 5 | no |
GO:0045296 | cadherin binding | 23.3333 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in WDR37_HUMAN |
---|---|---|---|---|
GO:0060255 | regulation of macromolecule metabolic process | 83.3333 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 83.3333 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 80.0000 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 80.0000 | 4 | no |
GO:0048522 | positive regulation of cellular process | 70.0000 | 4 | no |
GO:0048523 | negative regulation of cellular process | 60.0000 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 56.6667 | 4 | no |
GO:0051128 | regulation of cellular component organization | 53.3333 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 53.3333 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 50.0000 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 50.0000 | 5 | no |
GO:0031324 | negative regulation of cellular metabolic process | 50.0000 | 5 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 50.0000 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 50.0000 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 50.0000 | 5 | no |
GO:0008104 | protein localization | 50.0000 | 4 | no |
GO:0060341 | regulation of cellular localization | 46.6667 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 43.3333 | 5 | no |
GO:0032880 | regulation of protein localization | 43.3333 | 5 | no |
GO:0010646 | regulation of cell communication | 40.0000 | 4 | no |
GO:0031399 | regulation of protein modification process | 40.0000 | 6 | no |
GO:0070201 | regulation of establishment of protein localization | 40.0000 | 6 | no |
GO:1903829 | positive regulation of protein localization | 40.0000 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 40.0000 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 40.0000 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 40.0000 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 40.0000 | 5 | no |
GO:0051049 | regulation of transport | 36.6667 | 4 | no |
GO:0009966 | regulation of signal transduction | 36.6667 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 36.6667 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 36.6667 | 5 | no |
GO:0071702 | organic substance transport | 36.6667 | 4 | no |
GO:0006996 | organelle organization | 33.3333 | 4 | no |
GO:0031400 | negative regulation of protein modification process | 33.3333 | 7 | no |
GO:0051248 | negative regulation of protein metabolic process | 33.3333 | 6 | no |
GO:0051338 | regulation of transferase activity | 33.3333 | 4 | no |
GO:1904951 | positive regulation of establishment of protein localization | 33.3333 | 6 | no |
GO:0015031 | protein transport | 33.3333 | 4 | no |
GO:0071705 | nitrogen compound transport | 33.3333 | 4 | no |
GO:0010468 | regulation of gene expression | 30.0000 | 5 | no |
GO:0010563 | negative regulation of phosphorus metabolic process | 30.0000 | 6 | no |
GO:0022607 | cellular component assembly | 30.0000 | 4 | no |
GO:0042325 | regulation of phosphorylation | 30.0000 | 7 | no |
GO:0045936 | negative regulation of phosphate metabolic process | 30.0000 | 7 | no |
GO:0010941 | regulation of cell death | 26.6667 | 4 | no |
GO:0050821 | protein stabilization | 26.6667 | 4 | no |
GO:1902531 | regulation of intracellular signal transduction | 26.6667 | 5 | no |
GO:0033043 | regulation of organelle organization | 26.6667 | 5 | no |
GO:0043085 | positive regulation of catalytic activity | 26.6667 | 4 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 26.6667 | 6 | no |
GO:0001932 | regulation of protein phosphorylation | 26.6667 | 7 | no |
GO:0006886 | intracellular protein transport | 26.6667 | 4 | no |
GO:0051050 | positive regulation of transport | 26.6667 | 4 | no |
GO:0051726 | regulation of cell cycle | 26.6667 | 4 | no |
GO:0042981 | regulation of apoptotic process | 23.3333 | 6 | no |
GO:0043067 | regulation of programmed cell death | 23.3333 | 5 | no |
GO:0010638 | positive regulation of organelle organization | 23.3333 | 6 | no |
GO:0033044 | regulation of chromosome organization | 23.3333 | 6 | no |
GO:0051130 | positive regulation of cellular component organization | 23.3333 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 23.3333 | 6 | no |
GO:0051347 | positive regulation of transferase activity | 23.3333 | 5 | no |
GO:0071310 | cellular response to organic substance | 23.3333 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 23.3333 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.3333 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 23.3333 | 6 | no |
GO:1900180 | regulation of protein localization to nucleus | 23.3333 | 6 | no |
GO:1900182 | positive regulation of protein localization to nucleus | 23.3333 | 6 | no |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in WDR37_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 10.0000 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 10.0000 | 5 | no |
DOID:114 | heart disease | 10.0000 | 3 | no |
DOID:2843 | long QT syndrome | 6.6667 | 6 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
TNKS1_HUMAN | [view interactions] | High throughput | no | yes |
SETD2_HUMAN | [view interactions] | High throughput | no | yes |
PACS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLU_HUMAN | [view interactions] | High throughput | no | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
SGF29_HUMAN | [view interactions] | High throughput | no | yes |
LRC46_HUMAN | [view interactions] | High throughput | no | no |
TOM70_HUMAN | [view interactions] | High throughput | no | yes |
1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MECOM_HUMAN | [view interactions] | High throughput | no | yes |
EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H11_HUMAN | [view interactions] | High throughput | no | no |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
REL_HUMAN | [view interactions] | High throughput | no | yes |
1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB38_HUMAN | [view interactions] | High throughput | no | no |
FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
MEOX2_HUMAN | [view interactions] | High throughput | no | no |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TCPW_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PACS2_HUMAN | [view interactions] | High throughput | no | no |
IQCF1_HUMAN | [view interactions] | High throughput | no | no |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
CEBPB_HUMAN | [view interactions] | High throughput | no | no |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
BRD1_HUMAN | [view interactions] | High throughput | no | yes |
INS_HUMAN | [view interactions] | High throughput | no | no |
TAD2A_HUMAN | [view interactions] | High throughput | no | no |
KAT2B_HUMAN | [view interactions] | High throughput | no | yes |
EDC4_HUMAN | [view interactions] | High throughput | no | yes |
ST65G_HUMAN | [view interactions] | High throughput | no | yes |
TADA1_HUMAN | [view interactions] | High throughput | no | yes |
TAD2B_HUMAN | [view interactions] | High throughput | no | yes |
TAF5L_HUMAN | [view interactions] | High throughput | no | no |
TAF6L_HUMAN | [view interactions] | High throughput | no | yes |
ZZZ3_HUMAN | [view interactions] | High throughput | no | yes |
MBIP1_HUMAN | [view interactions] | High throughput | no | yes |
YETS2_HUMAN | [view interactions] | High throughput | no | no |
TADA3_HUMAN | [view interactions] | High throughput | no | yes |
KAT2A_HUMAN | [view interactions] | High throughput | no | no |
SUPT3_HUMAN | [view interactions] | High throughput | no | yes |
TRRAP_HUMAN | [view interactions] | High throughput | no | no |
TAF9B_HUMAN | [view interactions] | High throughput | no | no |
SP20H_HUMAN | [view interactions] | High throughput | no | yes |
CSR2B_HUMAN | [view interactions] | High throughput | no | no |
BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAN2_HUMAN | [view interactions] | High throughput | no | no |
ATG4A_HUMAN | [view interactions] | High throughput | no | yes |
CCD96_HUMAN | [view interactions] | High throughput | no | no |
1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LEAP2_HUMAN | [view interactions] | High throughput | no | no |
SPXN2_HUMAN | [view interactions] | High throughput | no | no |
RS4Y1_HUMAN | [view interactions] | High throughput | no | yes |
BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
RU1C_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |