ANS1B_HUMAN
Evidence for PS localization
Functions
Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing. [View more on UniProt]
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 64%
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Interacting regions
Canonical [ANS1B_HUMAN]
Isoform [H0YJZ1] alignment
Isoform [H0YI72] alignment
Isoform [F8VVQ4] alignment
Isoform [Q7Z6G8-10] alignment
Isoform [F8VR14] alignment
Isoform [Q7Z6G8-2] alignment
Isoform [Q7Z6G8-3] alignment
Isoform [Q7Z6G8-4] alignment
Isoform [Q7Z6G8-5] alignment
Isoform [Q7Z6G8-6] alignment
Isoform [Q7Z6G8-7] alignment
Isoform [Q7Z6G8-8] alignment
Isoform [Q7Z6G8-9] alignment
Isoform [R4GNJ0] alignment
Isoform [R4GMS8] alignment
Isoform [R4GMN5] alignment
Isoform [R4GMQ4] alignment
Isoform [R4GN07] alignment
Isoform [R4GN70] alignment
Isoform [R4GN73] alignment
Isoform [R4GN78] alignment
Isoform [A0A804HKX1] alignment
LOADING 13%
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ANS1B_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 32.8467 | 4 | no |
| GO:0000166 | nucleotide binding | 31.3869 | 4 | no |
| GO:0017076 | purine nucleotide binding | 29.9270 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 29.9270 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.1971 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 22.6277 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.6277 | 5 | no |
| GO:0005524 | ATP binding | 21.8978 | 5 | no |
| GO:0046875 | ephrin receptor binding | 1.4599 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ANS1B_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 44.5255 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 39.4161 | 4 | no |
| GO:0010646 | regulation of cell communication | 37.2263 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 36.4964 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 32.1168 | 4 | no |
| GO:0006996 | organelle organization | 29.9270 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 29.1971 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 29.1971 | 4 | no |
| GO:0008104 | protein localization | 28.4672 | 4 | no |
| GO:0009966 | regulation of signal transduction | 27.0073 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.5474 | 4 | no |
| GO:0022607 | cellular component assembly | 24.8175 | 4 | no |
| GO:0030030 | cell projection organization | 24.0876 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 23.3577 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 23.3577 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.6277 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 21.8978 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 21.8978 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 21.8978 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 21.1679 | 4 | no |
| GO:0010468 | regulation of gene expression | 21.1679 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 21.1679 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 20.4380 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 20.4380 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.4380 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| 5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADPRH_HUMAN | [view interactions] | High throughput | no | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP3M2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARG33_HUMAN | [view interactions] | High throughput | no | no |
| ARHG7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A3_HUMAN | [view interactions] | High throughput | no | yes |
| ATLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BSN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTBDH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| C1QA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| C1QB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| C1QC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASS4_HUMAN | [view interactions] | High throughput | no | yes |