C1TC_HUMAN
Evidence for PS localization
Functions
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 73%
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Interacting regions
Canonical [C1TC_HUMAN]
Isoform [V9GZ32] alignment
Isoform [V9GYY3] alignment
Isoform [V9GZ78] alignment
Isoform [A0A494C1T2] alignment
Isoform [A0A8V8TMA4] alignment
Isoform [A0A8V8TMA9] alignment
Isoform [A0A8V8TKR5] alignment
Isoform [A0A8V8TKS0] alignment
Isoform [A0A8V8TKT4] alignment
Isoform [A0A8V8TL46] alignment
Isoform [A0A8V8TL50] alignment
Isoform [A0A8C8UXK2] alignment
Isoform [F5H2F4] alignment
LOADING 25%
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in C1TC_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 38.2716 | 4 | yes |
| GO:0043168 | anion binding | 37.0370 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 35.8025 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 34.5679 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.5679 | 4 | yes |
| GO:0003723 | RNA binding | 32.0988 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 30.8642 | 6 | yes |
| GO:0005524 | ATP binding | 29.6296 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 29.6296 | 5 | yes |
| GO:0043169 | cation binding | 25.9259 | 4 | no |
| GO:0019900 | kinase binding | 24.6914 | 4 | no |
| GO:0046872 | metal ion binding | 23.4568 | 5 | no |
| GO:0019901 | protein kinase binding | 22.2222 | 5 | no |
| GO:0004329 | formate-tetrahydrofolate ligase activity | 2.4691 | 4 | yes |
| GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity | 2.4691 | 6 | yes |
| GO:0004486 | methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity | 2.4691 | 5 | yes |
| GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity | 2.4691 | 6 | yes |
| GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity | 2.4691 | 6 | yes |
| GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | 2.4691 | 4 | yes |
| GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | 2.4691 | 4 | yes |
| GO:0019238 | cyclohydrolase activity | 2.4691 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in C1TC_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 51.8519 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 50.6173 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 50.6173 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.1481 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 46.9136 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 46.9136 | 5 | no |
| GO:0010646 | regulation of cell communication | 45.6790 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 45.6790 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 44.4444 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 43.2099 | 4 | no |
| GO:0010468 | regulation of gene expression | 41.9753 | 6 | no |
| GO:0009893 | positive regulation of metabolic process | 38.2716 | 4 | no |
| GO:0009966 | regulation of signal transduction | 37.0370 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.0370 | 5 | no |
| GO:0022607 | cellular component assembly | 37.0370 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.5679 | 5 | no |
| GO:0006996 | organelle organization | 33.3333 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.0988 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 32.0988 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 32.0988 | 5 | no |
| GO:0051049 | regulation of transport | 32.0988 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.6296 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 29.6296 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 29.6296 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.6296 | 5 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| ABCF2_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| AL1B1_HUMAN | [view interactions] | High throughput | no | yes |
| ANGI_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANM8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASXL1_HUMAN | [view interactions] | High throughput | no | no |
| ASXL2_HUMAN | [view interactions] | High throughput | no | no |
| ATG10_HUMAN | [view interactions] | High throughput | no | yes |
| ATG3_HUMAN | [view interactions] | High throughput | no | yes |