FKBP4_HUMAN
Evidence for PS localization
Functions
Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FKBP4_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 42.2535 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 42.2535 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 42.2535 | 4 | yes |
| GO:0005524 | ATP binding | 38.0282 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 38.0282 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 38.0282 | 5 | yes |
| GO:0019900 | kinase binding | 26.7606 | 4 | no |
| GO:0019901 | protein kinase binding | 26.7606 | 5 | no |
| GO:0003723 | RNA binding | 23.9437 | 4 | yes |
| GO:0046872 | metal ion binding | 21.1268 | 4 | no |
| GO:0048156 | tau protein binding | 12.6761 | 4 | yes |
| GO:0019001 | guanyl nucleotide binding | 9.8592 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 9.8592 | 5 | yes |
| GO:0140297 | DNA-binding transcription factor binding | 9.8592 | 4 | yes |
| GO:0005525 | GTP binding | 8.4507 | 5 | yes |
| GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding | 8.4507 | 5 | yes |
| GO:0016922 | nuclear receptor binding | 5.6338 | 6 | yes |
| GO:0035259 | nuclear glucocorticoid receptor binding | 2.8169 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FKBP4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 59.1549 | 4 | no |
| GO:0010646 | regulation of cell communication | 47.8873 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.8873 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 47.8873 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 46.4789 | 4 | yes |
| GO:0006996 | organelle organization | 46.4789 | 4 | no |
| GO:0009966 | regulation of signal transduction | 46.4789 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 46.4789 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 46.4789 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.0704 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 45.0704 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 42.2535 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 39.4366 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.0282 | 5 | no |
| GO:0071310 | cellular response to organic substance | 38.0282 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.6197 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.6197 | 5 | no |
| GO:0010468 | regulation of gene expression | 35.2113 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 33.8028 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.8028 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.8028 | 5 | no |
| GO:0022607 | cellular component assembly | 33.8028 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 33.8028 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 33.8028 | 6 | no |
| GO:0051049 | regulation of transport | 32.3944 | 4 | no |
| GO:0033043 | regulation of organelle organization | 32.3944 | 5 | yes |
| GO:0036211 | protein modification process | 32.3944 | 4 | yes |
| GO:0043412 | macromolecule modification | 32.3944 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 32.3944 | 4 | no |
| GO:0010941 | regulation of cell death | 32.3944 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 30.9859 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.9859 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 29.5775 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 29.5775 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.5775 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 29.5775 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 29.5775 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.5775 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.5775 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.1690 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 28.1690 | 7 | no |
| GO:0006355 | regulation of DNA-templated transcription | 26.7606 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 26.7606 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 26.7606 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.7606 | 6 | no |
| GO:0051493 | regulation of cytoskeleton organization | 26.7606 | 6 | yes |
| GO:0043085 | positive regulation of catalytic activity | 26.7606 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 26.7606 | 5 | no |
| GO:0008104 | protein localization | 25.3521 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 25.3521 | 7 | no |
| GO:0051338 | regulation of transferase activity | 25.3521 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.3521 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.9437 | 7 | no |
| GO:0010647 | positive regulation of cell communication | 23.9437 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.9437 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.9437 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 23.9437 | 4 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 23.9437 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 23.9437 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 23.9437 | 6 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 23.9437 | 4 | no |
| GO:0051050 | positive regulation of transport | 22.5352 | 4 | no |
| GO:0018193 | peptidyl-amino acid modification | 22.5352 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 22.5352 | 4 | yes |
| GO:0051129 | negative regulation of cellular component organization | 22.5352 | 5 | yes |
| GO:0031400 | negative regulation of protein modification process | 22.5352 | 7 | no |
| GO:0009967 | positive regulation of signal transduction | 21.1268 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 21.1268 | 6 | no |
| GO:0014070 | response to organic cyclic compound | 21.1268 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 21.1268 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 21.1268 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.1268 | 5 | no |
| GO:0042327 | positive regulation of phosphorylation | 21.1268 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 21.1268 | 7 | no |
| GO:0051347 | positive regulation of transferase activity | 21.1268 | 5 | no |
| GO:0080134 | regulation of response to stress | 21.1268 | 4 | no |
| GO:0032271 | regulation of protein polymerization | 19.7183 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 19.7183 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 14.0845 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 14.0845 | 6 | yes |
| GO:0032886 | regulation of microtubule-based process | 12.6761 | 4 | yes |
| GO:0070507 | regulation of microtubule cytoskeleton organization | 12.6761 | 5 | yes |
| GO:0010639 | negative regulation of organelle organization | 11.2676 | 6 | yes |
| GO:0010975 | regulation of neuron projection development | 11.2676 | 7 | yes |
| GO:0006811 | ion transport | 9.8592 | 4 | yes |
| GO:0006812 | cation transport | 9.8592 | 5 | yes |
| GO:0031110 | regulation of microtubule polymerization or depolymerization | 9.8592 | 6 | yes |
| GO:0031113 | regulation of microtubule polymerization | 9.8592 | 6 | yes |
| GO:0031333 | negative regulation of protein-containing complex assembly | 9.8592 | 6 | yes |
| GO:1902904 | negative regulation of supramolecular fiber organization | 9.8592 | 6 | yes |
| GO:0048732 | gland development | 8.4507 | 4 | yes |
| GO:0051494 | negative regulation of cytoskeleton organization | 8.4507 | 7 | yes |
| GO:0030001 | metal ion transport | 7.0423 | 6 | yes |
| GO:0031345 | negative regulation of cell projection organization | 7.0423 | 6 | yes |
| GO:0032272 | negative regulation of protein polymerization | 7.0423 | 7 | yes |
| GO:0010977 | negative regulation of neuron projection development | 5.6338 | 7 | yes |
| GO:0018208 | peptidyl-proline modification | 5.6338 | 6 | yes |
| GO:0030518 | intracellular steroid hormone receptor signaling pathway | 5.6338 | 4 | yes |
| GO:0043401 | steroid hormone mediated signaling pathway | 5.6338 | 4 | yes |
| GO:0000413 | protein peptidyl-prolyl isomerization | 4.2254 | 7 | yes |
| GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 4.2254 | 7 | yes |
| GO:0031115 | negative regulation of microtubule polymerization | 4.2254 | 7 | yes |
| GO:0000041 | transition metal ion transport | 2.8169 | 7 | yes |
| GO:0006463 | steroid hormone receptor complex assembly | 2.8169 | 6 | yes |
| GO:0006825 | copper ion transport | 2.8169 | 8 | yes |
| GO:0030521 | androgen receptor signaling pathway | 2.8169 | 5 | yes |
| GO:0030850 | prostate gland development | 2.8169 | 4 | yes |
| GO:0046661 | male sex differentiation | 2.8169 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in FKBP4_HUMAN |
|---|---|---|---|---|
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 2.8169 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.8169 | 6 | no |
| DOID:440 | neuromuscular disease | 2.8169 | 5 | no |
| DOID:574 | peripheral nervous system disease | 2.8169 | 3 | no |
| DOID:870 | neuropathy | 2.8169 | 4 | no |
| DOID:0050700 | cardiomyopathy | 2.8169 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 2.8169 | 5 | no |
| DOID:114 | heart disease | 2.8169 | 3 | no |
| DOID:2843 | long QT syndrome | 2.8169 | 6 | no |
| DOID:1289 | neurodegenerative disease | 2.8169 | 4 | no |
| DOID:331 | central nervous system disease | 2.8169 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| S10A1_HUMAN | [view interactions] | Low throughput | no | yes |
| S10A2_HUMAN | [view interactions] | Low throughput | no | no |
| S10A6_HUMAN | [view interactions] | Low throughput | no | yes |
| AGO2_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GLMN_HUMAN | [view interactions] | Low throughput | no | no |
| GCR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| PAHX_HUMAN | [view interactions] | Low throughput | no | yes |
| IRF4_HUMAN | [view interactions] | Low throughput | no | no |
| HSF1_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DNMT1_HUMAN | [view interactions] | Low throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLSI_HUMAN | [view interactions] | High throughput | no | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| TXD12_HUMAN | [view interactions] | High throughput | no | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| NCOA7_HUMAN | [view interactions] | High throughput | no | yes |
| PTN2_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| DC1I1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F120C_HUMAN | [view interactions] | High throughput | no | yes |
| GLE1_HUMAN | [view interactions] | High throughput | no | yes |
| SYMPK_HUMAN | [view interactions] | High throughput | no | yes |
| TRI56_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2551_HUMAN | [view interactions] | High throughput | no | no |
| SURF1_HUMAN | [view interactions] | High throughput | no | yes |
| MK11_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR2_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| DC1I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF6_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKG2_HUMAN | [view interactions] | High throughput | no | yes |
| AAKG1_HUMAN | [view interactions] | High throughput | no | no |
| P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| GBRAP_HUMAN | [view interactions] | High throughput | no | no |
| FOXO3_HUMAN | [view interactions] | High throughput | no | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKB_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK3_HUMAN | [view interactions] | High throughput | no | no |
| AHSA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| CD37L_HUMAN | [view interactions] | High throughput | no | yes |
| CHRD1_HUMAN | [view interactions] | High throughput | no | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| LSM7_HUMAN | [view interactions] | High throughput | no | yes |
| TEBP_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP19_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| CE290_HUMAN | [view interactions] | High throughput | no | no |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| NPB_HUMAN | [view interactions] | High throughput | no | no |
| MGME1_HUMAN | [view interactions] | High throughput | no | yes |
| HS905_HUMAN | [view interactions] | High throughput | no | no |
| H90B4_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| PHLP1_HUMAN | [view interactions] | High throughput | no | yes |
| STK11_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| MP2K7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| KPSH1_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCG_HUMAN | [view interactions] | High throughput | no | no |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| LIMK2_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILK_HUMAN | [view interactions] | High throughput | no | no |
| MYLK_HUMAN | [view interactions] | High throughput | no | no |
| ST32C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| MK15_HUMAN | [view interactions] | High throughput | no | no |
| NEK7_HUMAN | [view interactions] | High throughput | no | yes |
| KPSH2_HUMAN | [view interactions] | High throughput | no | no |
| TSSK2_HUMAN | [view interactions] | High throughput | no | no |
| TSSK1_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| DYRK4_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LOXH1_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| CHK2_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC3_HUMAN | [view interactions] | High throughput | no | yes |
| NPHP1_HUMAN | [view interactions] | High throughput | no | yes |
| OFD1_HUMAN | [view interactions] | High throughput | no | yes |
| NEK8_HUMAN | [view interactions] | High throughput | no | yes |
| MKS1_HUMAN | [view interactions] | High throughput | no | no |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| POC1A_HUMAN | [view interactions] | High throughput | no | yes |
| RPGR_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| PPE2_HUMAN | [view interactions] | High throughput | no | no |
| NFYC_HUMAN | [view interactions] | High throughput | no | no |
| DDR2_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ACVR1_HUMAN | [view interactions] | High throughput | no | yes |
| SMUF2_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| MCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRGR_HUMAN | [view interactions] | High throughput | no | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARAF_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| TRPC1_HUMAN | [view interactions] | High throughput | no | yes |
| TRPC4_HUMAN | [view interactions] | High throughput | no | no |
| TRPC5_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| M4K1_HUMAN | [view interactions] | High throughput | no | no |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTSS2_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SARDH_HUMAN | [view interactions] | High throughput | no | yes |
| TAF9_HUMAN | [view interactions] | High throughput | no | yes |
| MCM3_HUMAN | [view interactions] | High throughput | no | no |
| MCM4_HUMAN | [view interactions] | High throughput | no | yes |
| OGA_HUMAN | [view interactions] | High throughput | no | yes |
| DYL2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| HSP72_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARP10_HUMAN | [view interactions] | Computational | no | no |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCTN6_HUMAN | [view interactions] | Computational | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAZA3_HUMAN | [view interactions] | Computational | no | no |
| DCTN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPID_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ATOX1_HUMAN | [view interactions] | Computational | no | no |
| DCTN5_HUMAN | [view interactions] | Computational | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HS71B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DCTN3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FKBP5_HUMAN | [view interactions] | Computational | no | yes |
| DCTN4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DC1L1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |