SHLB2_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SHLB2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 29.7297 | 4 | no |
| GO:0045296 | cadherin binding | 27.0270 | 4 | yes |
| GO:0019900 | kinase binding | 27.0270 | 4 | no |
| GO:0000166 | nucleotide binding | 27.0270 | 4 | no |
| GO:0017076 | purine nucleotide binding | 24.3243 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 24.3243 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.3243 | 4 | no |
| GO:0003723 | RNA binding | 21.6216 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SHLB2_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 62.1622 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 62.1622 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 62.1622 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 59.4595 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 59.4595 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 56.7568 | 4 | no |
| GO:0010646 | regulation of cell communication | 51.3514 | 4 | no |
| GO:0006996 | organelle organization | 48.6486 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 48.6486 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 48.6486 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 48.6486 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 45.9459 | 4 | no |
| GO:0022607 | cellular component assembly | 45.9459 | 4 | no |
| GO:0043933 | protein-containing complex organization | 45.9459 | 4 | no |
| GO:0010468 | regulation of gene expression | 45.9459 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.2432 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 43.2432 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 43.2432 | 5 | no |
| GO:0009966 | regulation of signal transduction | 40.5405 | 4 | no |
| GO:0008104 | protein localization | 37.8378 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 37.8378 | 5 | no |
| GO:0051049 | regulation of transport | 37.8378 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 37.8378 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 35.1351 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 35.1351 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 35.1351 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 32.4324 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.4324 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 32.4324 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 32.4324 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 32.4324 | 4 | no |
| GO:0061024 | membrane organization | 29.7297 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 29.7297 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 29.7297 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.7297 | 5 | no |
| GO:0032880 | regulation of protein localization | 29.7297 | 5 | no |
| GO:0060341 | regulation of cellular localization | 29.7297 | 4 | no |
| GO:0033043 | regulation of organelle organization | 29.7297 | 5 | no |
| GO:0031399 | regulation of protein modification process | 27.0270 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 27.0270 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 27.0270 | 5 | no |
| GO:0051050 | positive regulation of transport | 27.0270 | 4 | no |
| GO:0071310 | cellular response to organic substance | 27.0270 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.0270 | 5 | no |
| GO:0023056 | positive regulation of signaling | 27.0270 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.0270 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.0270 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.3243 | 6 | no |
| GO:0065003 | protein-containing complex assembly | 24.3243 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 24.3243 | 7 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 24.3243 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.3243 | 5 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 24.3243 | 6 | no |
| GO:0051254 | positive regulation of RNA metabolic process | 24.3243 | 6 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 24.3243 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 24.3243 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.3243 | 5 | no |
| GO:0007010 | cytoskeleton organization | 21.6216 | 5 | no |
| GO:0022411 | cellular component disassembly | 21.6216 | 4 | no |
| GO:0071702 | organic substance transport | 21.6216 | 4 | no |
| GO:0071705 | nitrogen compound transport | 21.6216 | 4 | no |
| GO:0030030 | cell projection organization | 21.6216 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.6216 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 21.6216 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 21.6216 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.6216 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SREK1_HUMAN | [view interactions] | Low throughput | no | yes |
| SHLB1_HUMAN | [view interactions] | Low throughput | no | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| GA45G_HUMAN | [view interactions] | High throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| PA2G4_HUMAN | [view interactions] | High throughput | no | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| IRAK2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD3_HUMAN | [view interactions] | High throughput | no | yes |
| OBSCN_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| PPL13_HUMAN | [view interactions] | High throughput | no | no |
| PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCD7_HUMAN | [view interactions] | High throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTAQ1_HUMAN | [view interactions] | High throughput | no | yes |
| KRA93_HUMAN | [view interactions] | High throughput | no | no |
| KRA45_HUMAN | [view interactions] | High throughput | no | no |
| KR108_HUMAN | [view interactions] | High throughput | no | no |
| KR511_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| EFHC1_HUMAN | [view interactions] | High throughput | no | yes |
| FBX8_HUMAN | [view interactions] | High throughput | no | yes |
| CASP6_HUMAN | [view interactions] | High throughput | no | no |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGA1_HUMAN | [view interactions] | High throughput | no | no |
| CD158_HUMAN | [view interactions] | High throughput | no | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP6R2_HUMAN | [view interactions] | High throughput | no | no |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| CEP83_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| LNX2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MO4L1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOS5_HUMAN | [view interactions] | High throughput | no | yes |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMI_HUMAN | [view interactions] | High throughput | no | yes |
| TEX11_HUMAN | [view interactions] | High throughput | no | no |
| CDN2D_HUMAN | [view interactions] | High throughput | no | no |
| EXOS1_HUMAN | [view interactions] | High throughput | no | yes |
| CCND3_HUMAN | [view interactions] | High throughput | no | no |
| LSM3_HUMAN | [view interactions] | High throughput | no | yes |
| FHL3_HUMAN | [view interactions] | High throughput | no | no |
| CNOT7_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYAG_HUMAN | [view interactions] | High throughput | no | yes |
| KR101_HUMAN | [view interactions] | High throughput | no | no |
| RSPH1_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| RABE2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN302_HUMAN | [view interactions] | High throughput | no | no |
| UBR3_HUMAN | [view interactions] | High throughput | no | yes |
| MBNL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC6_HUMAN | [view interactions] | High throughput | no | no |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| GMPPB_HUMAN | [view interactions] | High throughput | no | yes |
| SSUH2_HUMAN | [view interactions] | High throughput | no | no |
| BTBD1_HUMAN | [view interactions] | High throughput | no | yes |
| BRDT_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| SLX4_HUMAN | [view interactions] | High throughput | no | yes |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AASD1_HUMAN | [view interactions] | High throughput | no | yes |
| LZTL1_HUMAN | [view interactions] | High throughput | no | no |
| RUSD2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BLMH_HUMAN | [view interactions] | High throughput | no | yes |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| CRTAP_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| T2EA_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THG1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL2_HUMAN | [view interactions] | High throughput | no | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| AIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1S_HUMAN | [view interactions] | High throughput | no | no |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN207_HUMAN | [view interactions] | High throughput | no | yes |
| DPCD_HUMAN | [view interactions] | High throughput | no | yes |
| PFD6_HUMAN | [view interactions] | High throughput | no | yes |
| DAA10_HUMAN | [view interactions] | High throughput | no | yes |
| ANM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RINI_HUMAN | [view interactions] | High throughput | no | yes |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |