SH3K1_HUMAN
Evidence for PS localization
Functions
Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may be inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit . May be involved in regulation of cell adhesion; promotes the interaction between TTK2B and PDCD6IP. May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4. Is involved in modulation of tumor necrosis factor mediated apoptosis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Has an essential role in the stimulation of B cell activation (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI004159 | LIG_ActinCP_CPI_1 | LIG | 476 | 494 | - |
| ELMI004159 | LIG_ActinCP_CPI_1 | LIG | 476 | 494 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SH3K1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 34.9206 | 4 | no |
| GO:0000166 | nucleotide binding | 30.1587 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.1587 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.1587 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.3651 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.8095 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.8095 | 5 | no |
| GO:0005524 | ATP binding | 23.0159 | 5 | no |
| GO:0003723 | RNA binding | 22.2222 | 4 | no |
| GO:0019900 | kinase binding | 21.4286 | 4 | no |
| GO:0043169 | cation binding | 21.4286 | 4 | no |
| GO:0046872 | metal ion binding | 20.6349 | 5 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 14.2857 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 13.4921 | 5 | yes |
| GO:0017124 | SH3 domain binding | 11.1111 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SH3K1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 65.0794 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 55.5556 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.5556 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 55.5556 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 53.1746 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 51.5873 | 4 | no |
| GO:0010646 | regulation of cell communication | 46.8254 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 44.4444 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 44.4444 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 44.4444 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 43.6508 | 4 | no |
| GO:0009966 | regulation of signal transduction | 42.8571 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 42.8571 | 5 | no |
| GO:0010468 | regulation of gene expression | 42.0635 | 6 | no |
| GO:0008104 | protein localization | 38.0952 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 38.0952 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.5079 | 5 | no |
| GO:0022607 | cellular component assembly | 34.9206 | 4 | no |
| GO:0006996 | organelle organization | 33.3333 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.7460 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.9524 | 4 | no |
| GO:0051049 | regulation of transport | 30.1587 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.3651 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 29.3651 | 5 | no |
| GO:0071702 | organic substance transport | 28.5714 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 28.5714 | 4 | no |
| GO:0071705 | nitrogen compound transport | 27.7778 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 27.7778 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.7778 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.7778 | 5 | no |
| GO:0033043 | regulation of organelle organization | 27.7778 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.7778 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.9841 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 26.9841 | 5 | no |
| GO:0023056 | positive regulation of signaling | 26.9841 | 4 | no |
| GO:0036211 | protein modification process | 26.9841 | 4 | no |
| GO:0043412 | macromolecule modification | 26.9841 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 26.9841 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.9841 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.9841 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 26.9841 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.9841 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.1905 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.1905 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 26.1905 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.3968 | 6 | no |
| GO:0015031 | protein transport | 25.3968 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 25.3968 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 25.3968 | 7 | no |
| GO:0043933 | protein-containing complex organization | 25.3968 | 4 | no |
| GO:0030030 | cell projection organization | 24.6032 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.6032 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 24.6032 | 4 | no |
| GO:0023057 | negative regulation of signaling | 23.8095 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 23.0159 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 23.0159 | 4 | no |
| GO:2000145 | regulation of cell motility | 23.0159 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.2222 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.2222 | 5 | no |
| GO:0030334 | regulation of cell migration | 22.2222 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.4286 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.4286 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.4286 | 6 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.4286 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 21.4286 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 21.4286 | 5 | no |
| GO:0002684 | positive regulation of immune system process | 20.6349 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 20.6349 | 4 | no |
| GO:0098657 | import into cell | 18.2540 | 4 | yes |
| GO:0007010 | cytoskeleton organization | 17.4603 | 5 | yes |
| GO:0002694 | regulation of leukocyte activation | 12.6984 | 4 | yes |
| GO:0022604 | regulation of cell morphogenesis | 12.6984 | 5 | yes |
| GO:0050865 | regulation of cell activation | 12.6984 | 4 | yes |
| GO:0051249 | regulation of lymphocyte activation | 12.6984 | 5 | yes |
| GO:0006915 | apoptotic process | 11.1111 | 4 | yes |
| GO:0002696 | positive regulation of leukocyte activation | 8.7302 | 5 | yes |
| GO:0050867 | positive regulation of cell activation | 8.7302 | 5 | yes |
| GO:0051251 | positive regulation of lymphocyte activation | 8.7302 | 6 | yes |
| GO:0097435 | supramolecular fiber organization | 8.7302 | 4 | yes |
| GO:0007015 | actin filament organization | 7.1429 | 5 | yes |
| GO:0050864 | regulation of B cell activation | 3.1746 | 6 | yes |
| GO:0050871 | positive regulation of B cell activation | 2.3810 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| M3K4_HUMAN | [view interactions] | Low throughput | no | yes |
| LYOX_HUMAN | [view interactions] | Low throughput | no | no |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAB7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FRS3_HUMAN | [view interactions] | Low throughput | no | no |
| CD2AP_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| VPS4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHM2A_HUMAN | [view interactions] | Low throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | Low throughput | no | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHLB1_HUMAN | [view interactions] | Low throughput | no | yes |
| PDCD6_HUMAN | [view interactions] | Low throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBC9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASAP2_HUMAN | [view interactions] | Low throughput | no | yes |
| SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ZO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TAF6_HUMAN | [view interactions] | Low throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DAB1_HUMAN | [view interactions] | Low throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DRD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SYPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD2_HUMAN | [view interactions] | Low throughput | no | no |
| PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
| RHG27_HUMAN | [view interactions] | Low throughput | no | no |
| SHLB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| TTP_HUMAN | [view interactions] | Low throughput | no | yes |
| CATB_HUMAN | [view interactions] | Low throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | Low throughput | no | yes |
| MET_HUMAN | [view interactions] | Low throughput | no | yes |
| KIT_HUMAN | [view interactions] | Low throughput | no | no |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MB12A_HUMAN | [view interactions] | Low throughput | no | yes |
| NPHN_HUMAN | [view interactions] | Low throughput | no | no |
| PODO_HUMAN | [view interactions] | Low throughput | no | no |
| SPY1_HUMAN | [view interactions] | Low throughput | no | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SEPT9_HUMAN | [view interactions] | Low throughput | no | no |
| SEPT2_HUMAN | [view interactions] | Low throughput | no | no |
| SEPT6_HUMAN | [view interactions] | Low throughput | no | yes |
| SHIP2_HUMAN | [view interactions] | Low throughput | no | yes |
| ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTC_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SH3G3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BLNK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| 3BP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CBLB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DEND_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARAP3_HUMAN | [view interactions] | Low throughput | no | no |
| SHIP1_HUMAN | [view interactions] | Low throughput | no | no |
| SPY2_HUMAN | [view interactions] | Low throughput | no | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN764_HUMAN | [view interactions] | High throughput | no | no |
| UBP27_HUMAN | [view interactions] | High throughput | no | no |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| RTKN2_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| MILK1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX28_HUMAN | [view interactions] | High throughput | no | yes |
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCP1L_HUMAN | [view interactions] | High throughput | no | no |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| P63_HUMAN | [view interactions] | High throughput | no | no |
| CHMP5_HUMAN | [view interactions] | High throughput | no | yes |
| KLC3_HUMAN | [view interactions] | High throughput | no | no |
| RP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP51_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| SGF29_HUMAN | [view interactions] | High throughput | no | yes |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| DNMBP_HUMAN | [view interactions] | High throughput | no | no |
| F167A_HUMAN | [view interactions] | High throughput | no | yes |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| SRS10_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLK3_HUMAN | [view interactions] | High throughput | no | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CSK23_HUMAN | [view interactions] | High throughput | no | no |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPR_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPL4_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| CDD_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSTF2_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24D_HUMAN | [view interactions] | High throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |
| TTC38_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLOD2_HUMAN | [view interactions] | High throughput | no | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
| AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
| PAPOA_HUMAN | [view interactions] | High throughput | no | yes |
| ITA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| INADL_HUMAN | [view interactions] | High throughput | no | no |
| SRGP1_HUMAN | [view interactions] | High throughput | no | no |
| ZMAT2_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GASP3_HUMAN | [view interactions] | High throughput | no | no |
| CRTP1_HUMAN | [view interactions] | High throughput | no | yes |
| KPRP_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| CC88B_HUMAN | [view interactions] | High throughput | no | no |
| KRA63_HUMAN | [view interactions] | High throughput | no | no |
| GGN_HUMAN | [view interactions] | High throughput | no | no |
| RPAB4_HUMAN | [view interactions] | High throughput | no | no |
| NELFA_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| DESI1_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHB6_HUMAN | [view interactions] | High throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| ZBT7B_HUMAN | [view interactions] | High throughput | no | no |
| PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| ZEP1_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| DEN2A_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| BMR1B_HUMAN | [view interactions] | High throughput | no | no |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPD2B_HUMAN | [view interactions] | High throughput | no | no |
| PHLB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHLB2_HUMAN | [view interactions] | High throughput | no | yes |
| SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GA2L1_HUMAN | [view interactions] | High throughput | no | yes |
| WIPF1_HUMAN | [view interactions] | High throughput | no | no |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WIPF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP7_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| MA7D3_HUMAN | [view interactions] | High throughput | no | no |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| GCP4_HUMAN | [view interactions] | High throughput | no | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT8_HUMAN | [view interactions] | High throughput | no | no |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP37B_HUMAN | [view interactions] | High throughput | no | yes |
| RB6I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC7_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| SH319_HUMAN | [view interactions] | High throughput | no | no |
| APC4_HUMAN | [view interactions] | High throughput | no | yes |
| CARL1_HUMAN | [view interactions] | High throughput | no | yes |
| PALMD_HUMAN | [view interactions] | High throughput | no | no |
| SLAI2_HUMAN | [view interactions] | High throughput | no | no |
| NHSL3_HUMAN | [view interactions] | High throughput | no | yes |
| APC5_HUMAN | [view interactions] | High throughput | no | yes |
| LEMD2_HUMAN | [view interactions] | High throughput | no | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| KTNB1_HUMAN | [view interactions] | High throughput | no | yes |
| PSRC1_HUMAN | [view interactions] | High throughput | no | no |
| BACD3_HUMAN | [view interactions] | High throughput | no | yes |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| PKP3_HUMAN | [view interactions] | High throughput | no | yes |
| FA83G_HUMAN | [view interactions] | High throughput | no | no |
| FL2D_HUMAN | [view interactions] | High throughput | no | yes |
| CDC16_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| SHCBP_HUMAN | [view interactions] | High throughput | no | no |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF7_HUMAN | [view interactions] | High throughput | no | yes |
| RNF34_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
| SAMD1_HUMAN | [view interactions] | High throughput | no | no |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| PSIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MDEAS_HUMAN | [view interactions] | High throughput | no | yes |
| KLF13_HUMAN | [view interactions] | High throughput | no | no |
| CIZ1_HUMAN | [view interactions] | High throughput | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A4_HUMAN | [view interactions] | High throughput | no | yes |
| CDK16_HUMAN | [view interactions] | High throughput | no | yes |
| I2BP2_HUMAN | [view interactions] | High throughput | no | yes |
| I2BP1_HUMAN | [view interactions] | High throughput | no | yes |
| DNMT1_HUMAN | [view interactions] | High throughput | no | no |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX28_HUMAN | [view interactions] | High throughput | no | yes |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRADD_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| MAP9_HUMAN | [view interactions] | High throughput | no | no |
| CYGB_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX25_HUMAN | [view interactions] | High throughput | no | no |
| M4K1_HUMAN | [view interactions] | High throughput | no | no |
| BCAP_HUMAN | [view interactions] | High throughput | no | no |
| PK3CD_HUMAN | [view interactions] | High throughput | no | no |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG8_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAP1_HUMAN | [view interactions] | High throughput | no | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN219_HUMAN | [view interactions] | High throughput | no | yes |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| GCDH_HUMAN | [view interactions] | High throughput | no | yes |
| FACR1_HUMAN | [view interactions] | High throughput | no | yes |
| S2512_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTF8_HUMAN | [view interactions] | High throughput | no | no |
| WASP_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |