SH3K1_HUMAN
Evidence for PS localization
Functions
Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may be inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit . May be involved in regulation of cell adhesion; promotes the interaction between TTK2B and PDCD6IP. May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4. Is involved in modulation of tumor necrosis factor mediated apoptosis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Has an essential role in the stimulation of B cell activation (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI004159 | LIG_ActinCP_CPI_1 | LIG | 476 | 494 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SH3K1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 29.2683 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 29.2683 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 28.4553 | 4 | no |
| GO:0003723 | RNA binding | 21.9512 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 21.9512 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.9512 | 5 | no |
| GO:0046872 | metal ion binding | 21.1382 | 4 | no |
| GO:0005524 | ATP binding | 21.1382 | 5 | no |
| GO:0019900 | kinase binding | 20.3252 | 4 | no |
| GO:0044389 | ubiquitin-like protein ligase binding | 15.4472 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 14.6341 | 5 | yes |
| GO:0017124 | SH3 domain binding | 10.5691 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SH3K1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.6016 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 54.4715 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 53.6585 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 52.0325 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 51.2195 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 51.2195 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 47.1545 | 4 | no |
| GO:0010646 | regulation of cell communication | 46.3415 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.5285 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.0894 | 5 | no |
| GO:0009966 | regulation of signal transduction | 40.6504 | 4 | no |
| GO:0010468 | regulation of gene expression | 38.2114 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 38.2114 | 5 | no |
| GO:0008104 | protein localization | 36.5854 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 35.7724 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 34.9593 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 34.9593 | 5 | no |
| GO:0006996 | organelle organization | 34.1463 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 34.1463 | 4 | no |
| GO:0051049 | regulation of transport | 34.1463 | 4 | no |
| GO:0022607 | cellular component assembly | 33.3333 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.5203 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.8943 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.8943 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.8943 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 30.8943 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.0813 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 29.2683 | 4 | yes |
| GO:0071702 | organic substance transport | 29.2683 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.2683 | 6 | no |
| GO:0033043 | regulation of organelle organization | 28.4553 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.6423 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.6423 | 5 | no |
| GO:0071705 | nitrogen compound transport | 27.6423 | 4 | no |
| GO:0010941 | regulation of cell death | 27.6423 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.8293 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.8293 | 4 | no |
| GO:0031399 | regulation of protein modification process | 26.8293 | 6 | no |
| GO:0015031 | protein transport | 26.0163 | 4 | no |
| GO:0036211 | protein modification process | 26.0163 | 4 | no |
| GO:0043412 | macromolecule modification | 26.0163 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 26.0163 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.0163 | 6 | no |
| GO:0023056 | positive regulation of signaling | 26.0163 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.0163 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 25.2033 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.2033 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.3902 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.3902 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 24.3902 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 24.3902 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 24.3902 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 24.3902 | 5 | no |
| GO:0071310 | cellular response to organic substance | 23.5772 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.5772 | 6 | no |
| GO:0043933 | protein-containing complex organization | 23.5772 | 4 | no |
| GO:0030030 | cell projection organization | 23.5772 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 23.5772 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 22.7642 | 4 | no |
| GO:0051050 | positive regulation of transport | 22.7642 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 22.7642 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 21.9512 | 4 | no |
| GO:2000145 | regulation of cell motility | 21.9512 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.9512 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 21.9512 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.1382 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.1382 | 4 | no |
| GO:0030334 | regulation of cell migration | 21.1382 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.1382 | 5 | no |
| GO:0060341 | regulation of cellular localization | 21.1382 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 21.1382 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.1382 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.1382 | 7 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 21.1382 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 21.1382 | 7 | no |
| GO:0032880 | regulation of protein localization | 20.3252 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 20.3252 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.3252 | 5 | no |
| GO:0060548 | negative regulation of cell death | 20.3252 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 20.3252 | 7 | no |
| GO:0006897 | endocytosis | 19.5122 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 17.8862 | 5 | yes |
| GO:0022604 | regulation of cell morphogenesis | 16.2602 | 5 | yes |
| GO:0002684 | positive regulation of immune system process | 13.8211 | 4 | yes |
| GO:0002694 | regulation of leukocyte activation | 10.5691 | 4 | yes |
| GO:0006915 | apoptotic process | 10.5691 | 4 | yes |
| GO:0050865 | regulation of cell activation | 10.5691 | 4 | yes |
| GO:0051249 | regulation of lymphocyte activation | 10.5691 | 5 | yes |
| GO:0097435 | supramolecular fiber organization | 8.9431 | 4 | yes |
| GO:0007015 | actin filament organization | 8.1301 | 5 | yes |
| GO:0008360 | regulation of cell shape | 8.1301 | 6 | yes |
| GO:0002696 | positive regulation of leukocyte activation | 6.5041 | 5 | yes |
| GO:0050867 | positive regulation of cell activation | 6.5041 | 5 | yes |
| GO:0051251 | positive regulation of lymphocyte activation | 6.5041 | 6 | yes |
| GO:0050864 | regulation of B cell activation | 3.2520 | 6 | yes |
| GO:0050871 | positive regulation of B cell activation | 2.4390 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SH3K1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 2.4390 | 3 | no |
| DOID:3490 | Noonan syndrome | 1.6260 | 3 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.6260 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 1.6260 | 6 | no |
| DOID:1289 | neurodegenerative disease | 1.6260 | 4 | no |
| DOID:440 | neuromuscular disease | 1.6260 | 5 | no |
| DOID:574 | peripheral nervous system disease | 1.6260 | 3 | no |
| DOID:870 | neuropathy | 1.6260 | 4 | no |
| DOID:0050701 | electroclinical syndrome | 1.6260 | 6 | no |
| DOID:0112202 | developmental and epileptic encephalopathy | 1.6260 | 7 | no |
| DOID:1826 | epilepsy | 1.6260 | 5 | no |
| DOID:936 | brain disease | 1.6260 | 4 | no |
| DOID:0050686 | organ system cancer | 1.6260 | 3 | no |
| DOID:193 | reproductive organ cancer | 1.6260 | 4 | no |
| DOID:0050155 | sensory system disease | 1.6260 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 1.6260 | 5 | no |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | 1.6260 | 6 | no |
| DOID:2742 | auditory system disease | 1.6260 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.6260 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
| RHG27_HUMAN | [view interactions] | Low throughput | no | no |
| SHLB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| TTP_HUMAN | [view interactions] | Low throughput | no | yes |
| CATB_HUMAN | [view interactions] | Low throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | Low throughput | no | yes |
| MET_HUMAN | [view interactions] | Low throughput | no | yes |
| KIT_HUMAN | [view interactions] | Low throughput | no | no |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MB12A_HUMAN | [view interactions] | Low throughput | no | yes |
| NPHN_HUMAN | [view interactions] | Low throughput | no | no |
| PODO_HUMAN | [view interactions] | Low throughput | no | no |
| SPY1_HUMAN | [view interactions] | Low throughput | no | yes |
| DYN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SEPT9_HUMAN | [view interactions] | Low throughput | no | no |
| SEPT2_HUMAN | [view interactions] | Low throughput | no | no |
| SEPT6_HUMAN | [view interactions] | Low throughput | no | yes |
| SHIP2_HUMAN | [view interactions] | Low throughput | no | yes |
| ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ACTC_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| SH3G3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BLNK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| 3BP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CBLB_HUMAN | [view interactions] | Low throughput | no | yes |
| SH3G2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DEND_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DAB2_HUMAN | [view interactions] | Low throughput | no | yes |
| PDC6I_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARAP3_HUMAN | [view interactions] | Low throughput | no | no |
| SHIP1_HUMAN | [view interactions] | Low throughput | no | no |
| SPY2_HUMAN | [view interactions] | Low throughput | no | yes |
| LYOX_HUMAN | [view interactions] | Low throughput | no | no |
| M3K4_HUMAN | [view interactions] | Low throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| FRS3_HUMAN | [view interactions] | Low throughput | no | no |
| RAB7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD2AP_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR1_HUMAN | [view interactions] | Low throughput | no | no |
| TGFR2_HUMAN | [view interactions] | Low throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPS4A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CHM2A_HUMAN | [view interactions] | Low throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | Low throughput | no | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ASAP2_HUMAN | [view interactions] | Low throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHLB1_HUMAN | [view interactions] | Low throughput | no | yes |
| PDCD6_HUMAN | [view interactions] | Low throughput | no | no |
| UBC9_HUMAN | [view interactions] | Low throughput | no | yes |
| SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ZO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TAF6_HUMAN | [view interactions] | Low throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DAB1_HUMAN | [view interactions] | Low throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DRD2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SYPH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CD2_HUMAN | [view interactions] | Low throughput | no | no |
| EPHB6_HUMAN | [view interactions] | High throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| ZBT7B_HUMAN | [view interactions] | High throughput | no | no |
| PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| ZEP1_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| DEN2A_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| BMR1B_HUMAN | [view interactions] | High throughput | no | no |
| SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPD2B_HUMAN | [view interactions] | High throughput | no | no |
| PHLB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHLB2_HUMAN | [view interactions] | High throughput | no | yes |
| SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GA2L1_HUMAN | [view interactions] | High throughput | no | yes |
| WIPF1_HUMAN | [view interactions] | High throughput | no | no |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WIPF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MAP7_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| MA7D3_HUMAN | [view interactions] | High throughput | no | no |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| GCP2_HUMAN | [view interactions] | High throughput | no | yes |
| GCP4_HUMAN | [view interactions] | High throughput | no | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP10_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT8_HUMAN | [view interactions] | High throughput | no | no |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP37B_HUMAN | [view interactions] | High throughput | no | yes |
| RB6I2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APC7_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| SH319_HUMAN | [view interactions] | High throughput | no | no |
| APC4_HUMAN | [view interactions] | High throughput | no | yes |
| CARL1_HUMAN | [view interactions] | High throughput | no | yes |
| PALMD_HUMAN | [view interactions] | High throughput | no | no |
| SLAI2_HUMAN | [view interactions] | High throughput | no | no |
| K1522_HUMAN | [view interactions] | High throughput | no | yes |
| APC5_HUMAN | [view interactions] | High throughput | no | yes |
| LEMD2_HUMAN | [view interactions] | High throughput | no | yes |
| DAG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| KTNB1_HUMAN | [view interactions] | High throughput | no | yes |
| PSRC1_HUMAN | [view interactions] | High throughput | no | no |
| BACD3_HUMAN | [view interactions] | High throughput | no | yes |
| P121A_HUMAN | [view interactions] | High throughput | no | yes |
| PKP3_HUMAN | [view interactions] | High throughput | no | yes |
| FA83G_HUMAN | [view interactions] | High throughput | no | no |
| FL2D_HUMAN | [view interactions] | High throughput | no | yes |
| CDC16_HUMAN | [view interactions] | High throughput | no | yes |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| SHCBP_HUMAN | [view interactions] | High throughput | no | no |
| SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF7_HUMAN | [view interactions] | High throughput | no | yes |
| RNF34_HUMAN | [view interactions] | High throughput | no | no |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
| SAMD1_HUMAN | [view interactions] | High throughput | no | no |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| PSIP1_HUMAN | [view interactions] | High throughput | no | yes |
| MDEAS_HUMAN | [view interactions] | High throughput | no | yes |
| KLF13_HUMAN | [view interactions] | High throughput | no | no |
| CIZ1_HUMAN | [view interactions] | High throughput | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1A_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A4_HUMAN | [view interactions] | High throughput | no | yes |
| CDK16_HUMAN | [view interactions] | High throughput | no | yes |
| I2BP2_HUMAN | [view interactions] | High throughput | no | yes |
| I2BP1_HUMAN | [view interactions] | High throughput | no | yes |
| DNMT1_HUMAN | [view interactions] | High throughput | no | no |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX28_HUMAN | [view interactions] | High throughput | no | yes |
| GTSE1_HUMAN | [view interactions] | High throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRADD_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| MAP9_HUMAN | [view interactions] | High throughput | no | no |
| CYGB_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX25_HUMAN | [view interactions] | High throughput | no | no |
| M4K1_HUMAN | [view interactions] | High throughput | no | no |
| BCAP_HUMAN | [view interactions] | High throughput | no | no |
| PK3CD_HUMAN | [view interactions] | High throughput | no | no |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARHG8_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAP1_HUMAN | [view interactions] | High throughput | no | no |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN219_HUMAN | [view interactions] | High throughput | no | yes |
| ODB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH1_HUMAN | [view interactions] | High throughput | no | yes |
| GCDH_HUMAN | [view interactions] | High throughput | no | yes |
| FACR1_HUMAN | [view interactions] | High throughput | no | yes |
| CMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTF8_HUMAN | [view interactions] | High throughput | no | no |
| SYNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASP_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| ZN764_HUMAN | [view interactions] | High throughput | no | no |
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| FBX28_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PALS1_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| MILK1_HUMAN | [view interactions] | High throughput | no | yes |
| RTKN2_HUMAN | [view interactions] | High throughput | no | no |
| CDC27_HUMAN | [view interactions] | High throughput | no | yes |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| UBP27_HUMAN | [view interactions] | High throughput | no | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM12_HUMAN | [view interactions] | High throughput | no | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCP1L_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RHG44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P63_HUMAN | [view interactions] | High throughput | no | no |
| KLC3_HUMAN | [view interactions] | High throughput | no | no |
| CHMP5_HUMAN | [view interactions] | High throughput | no | yes |
| RP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP51_HUMAN | [view interactions] | High throughput | no | yes |
| SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
| SGF29_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3HE_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| F167A_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRS10_HUMAN | [view interactions] | High throughput | no | yes |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLK3_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CSK23_HUMAN | [view interactions] | High throughput | no | no |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPR_HUMAN | [view interactions] | High throughput | no | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPL4_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDD_HUMAN | [view interactions] | High throughput | no | no |
| F263_HUMAN | [view interactions] | High throughput | no | yes |
| CSTF2_HUMAN | [view interactions] | High throughput | no | yes |
| DNMBP_HUMAN | [view interactions] | High throughput | no | no |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24D_HUMAN | [view interactions] | High throughput | no | yes |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| UFD1_HUMAN | [view interactions] | High throughput | no | no |
| GRPE1_HUMAN | [view interactions] | High throughput | no | yes |
| TTC38_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| ITA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR26_HUMAN | [view interactions] | High throughput | no | yes |
| SRGP1_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BHLH9_HUMAN | [view interactions] | High throughput | no | no |
| CRTP1_HUMAN | [view interactions] | High throughput | no | yes |
| KPRP_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| CC88B_HUMAN | [view interactions] | High throughput | no | no |
| GGN_HUMAN | [view interactions] | High throughput | no | no |
| RPAB4_HUMAN | [view interactions] | High throughput | no | no |
| NELFA_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| DESI1_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS27A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| UBB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HGF_HUMAN | [view interactions] | Computational | no | yes |
| VLDLR_HUMAN | [view interactions] | Computational | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EGF_HUMAN | [view interactions] | Computational | no | no |
| PTN3_HUMAN | [view interactions] | Computational | no | yes |
| EPS15_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RELN_HUMAN | [view interactions] | Computational | no | no |