Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TIM50_HUMAN

May participate in the release of snRNPs and SMN from the Cajal body. [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in TIM50_HUMAN
GO:0017076 purine nucleotide binding 22.8070 4 no
GO:0032555 purine ribonucleotide binding 22.8070 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.8070 4 no
GO:0003723 RNA binding 15.7895 4 yes
GO:0005126 cytokine receptor binding 5.2632 4 yes
GO:0070851 growth factor receptor binding 5.2632 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in TIM50_HUMAN
GO:0048522 positive regulation of cellular process 54.3860 4 no
GO:0006996 organelle organization 50.8772 4 yes
GO:0031323 regulation of cellular metabolic process 47.3684 4 no
GO:0080090 regulation of primary metabolic process 47.3684 4 no
GO:0051171 regulation of nitrogen compound metabolic process 42.1053 4 no
GO:0010646 regulation of cell communication 40.3509 4 no
GO:0048523 negative regulation of cellular process 40.3509 4 no
GO:0060255 regulation of macromolecule metabolic process 40.3509 4 no
GO:0051128 regulation of cellular component organization 36.8421 4 no
GO:0009889 regulation of biosynthetic process 36.8421 4 no
GO:0009966 regulation of signal transduction 36.8421 4 no
GO:0031326 regulation of cellular biosynthetic process 36.8421 5 no
GO:0022607 cellular component assembly 35.0877 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 35.0877 5 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0010468 regulation of gene expression 33.3333 5 no
GO:0071702 organic substance transport 31.5789 4 yes
GO:0071705 nitrogen compound transport 31.5789 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 31.5789 5 no
GO:0007010 cytoskeleton organization 29.8246 5 no
GO:0010647 positive regulation of cell communication 29.8246 5 no
GO:0023056 positive regulation of signaling 29.8246 4 no
GO:0048584 positive regulation of response to stimulus 29.8246 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 29.8246 5 no
GO:0051252 regulation of RNA metabolic process 29.8246 5 no
GO:1902531 regulation of intracellular signal transduction 29.8246 5 no
GO:0006355 regulation of DNA-templated transcription 28.0702 6 no
GO:0010604 positive regulation of macromolecule metabolic process 28.0702 5 no
GO:0031325 positive regulation of cellular metabolic process 28.0702 5 no
GO:0051246 regulation of protein metabolic process 28.0702 5 no
GO:0071310 cellular response to organic substance 28.0702 4 no
GO:1903506 regulation of nucleic acid-templated transcription 28.0702 7 no
GO:2001141 regulation of RNA biosynthetic process 28.0702 6 no
GO:0008104 protein localization 26.3158 4 yes
GO:0019220 regulation of phosphate metabolic process 26.3158 6 no
GO:0051174 regulation of phosphorus metabolic process 26.3158 5 no
GO:0009892 negative regulation of metabolic process 26.3158 4 no
GO:0009967 positive regulation of signal transduction 26.3158 5 no
GO:0043085 positive regulation of catalytic activity 26.3158 4 no
GO:0015031 protein transport 24.5614 4 yes
GO:0043412 macromolecule modification 24.5614 4 yes
GO:0031324 negative regulation of cellular metabolic process 24.5614 5 no
GO:0036211 protein modification process 22.8070 4 yes
GO:0010941 regulation of cell death 22.8070 4 no
GO:0042325 regulation of phosphorylation 22.8070 7 no
GO:0042981 regulation of apoptotic process 22.8070 6 no
GO:0043067 regulation of programmed cell death 22.8070 5 no
GO:0051247 positive regulation of protein metabolic process 22.8070 6 no
GO:0030030 cell projection organization 22.8070 4 no
GO:0033043 regulation of organelle organization 21.0526 5 no
GO:0051130 positive regulation of cellular component organization 21.0526 5 no
GO:0010562 positive regulation of phosphorus metabolic process 21.0526 6 no
GO:0010605 negative regulation of macromolecule metabolic process 21.0526 5 no
GO:0031399 regulation of protein modification process 21.0526 6 no
GO:0042127 regulation of cell population proliferation 21.0526 4 no
GO:0045937 positive regulation of phosphate metabolic process 21.0526 7 no
GO:0051172 negative regulation of nitrogen compound metabolic process 21.0526 5 no
GO:2000026 regulation of multicellular organismal development 21.0526 4 no
GO:0006886 intracellular protein transport 19.2982 4 yes
GO:0006796 phosphate-containing compound metabolic process 17.5439 4 yes
GO:0033365 protein localization to organelle 15.7895 5 yes
GO:0007005 mitochondrion organization 14.0351 5 yes
GO:0061024 membrane organization 14.0351 4 yes
GO:0072594 establishment of protein localization to organelle 14.0351 4 yes
GO:0006839 mitochondrial transport 12.2807 4 yes
GO:0070585 protein localization to mitochondrion 12.2807 6 yes
GO:0072655 establishment of protein localization to mitochondrion 12.2807 5 yes
GO:0044743 protein transmembrane import into intracellular organelle 10.5263 4 yes
GO:0065002 intracellular protein transmembrane transport 10.5263 4 yes
GO:0030150 protein import into mitochondrial matrix 8.7719 4 yes
GO:0007006 mitochondrial membrane organization 7.0175 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TI17B_HUMAN [view interactions] Low throughput no no
TR10B_HUMAN [view interactions] Low throughput no no
PIAS1_HUMAN [view interactions] Low throughput no yes
KCD21_HUMAN [view interactions] Low throughput no no
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
BMR1A_HUMAN [view interactions] High throughput no no
SMN_HUMAN [view interactions] High throughput no yes
TBA1C_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
CYFP2_HUMAN [view entry] [view interactions] High throughput yes yes
NMES1_HUMAN [view interactions] High throughput no no
MAIP1_HUMAN [view interactions] High throughput no yes
COQ9_HUMAN [view interactions] High throughput no yes
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
OPA3_HUMAN [view interactions] High throughput no yes
CISD3_HUMAN [view interactions] High throughput no yes
PTPM1_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
VAV_HUMAN [view interactions] High throughput no no
SOCS1_HUMAN [view interactions] High throughput no yes
MK07_HUMAN [view interactions] High throughput no yes
M3K14_HUMAN [view interactions] High throughput no yes
ELK1_HUMAN [view interactions] High throughput no yes
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
VAV2_HUMAN [view entry] [view interactions] High throughput yes yes
DOCK3_HUMAN [view entry] [view interactions] High throughput yes yes
MOT11_HUMAN [view interactions] High throughput no no
CTDS2_HUMAN [view interactions] High throughput no yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
PPE1_HUMAN [view interactions] High throughput no no
UN93B_HUMAN [view interactions] High throughput no yes
SP7_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
PELO_HUMAN [view interactions] High throughput no yes
AKTIP_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
SLAP1_HUMAN [view interactions] High throughput no yes
MAGD1_HUMAN [view interactions] High throughput no no
T22D1_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
PA1B2_HUMAN [view interactions] High throughput no yes
DYN1_HUMAN [view entry] [view interactions] High throughput yes yes
IKBA_HUMAN [view interactions] High throughput no yes
IKBB_HUMAN [view interactions] High throughput no no
IKBE_HUMAN [view entry] [view interactions] High throughput yes yes
IKKB_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] High throughput no yes
M3K3_HUMAN [view interactions] High throughput no no
NFKB2_HUMAN [view interactions] High throughput no yes
RELB_HUMAN [view interactions] High throughput no yes
RIPK1_HUMAN [view interactions] High throughput no yes
RIPK3_HUMAN [view interactions] High throughput no no
TAB2_HUMAN [view interactions] High throughput no yes
TNR1A_HUMAN [view interactions] High throughput no yes
TNR1B_HUMAN [view interactions] High throughput no no
TRAF1_HUMAN [view interactions] High throughput no no
TBA3E_HUMAN [view interactions] High throughput no no
TBB4B_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CBX6_HUMAN [view interactions] High throughput no yes
CBX7_HUMAN [view interactions] High throughput no yes
LMBL1_HUMAN [view interactions] High throughput no no
ERLN2_HUMAN [view entry] [view interactions] High throughput yes yes
COX15_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
COX14_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
PARL_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
RYK_HUMAN [view interactions] High throughput no no
AMFR_HUMAN [view interactions] High throughput no yes
TFE2_HUMAN [view interactions] High throughput no no
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
SMUF1_HUMAN [view interactions] High throughput no yes
NOS2_HUMAN [view interactions] High throughput no yes
PAN2_HUMAN [view interactions] High throughput no no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
ERR2_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
SUZ12_HUMAN [view interactions] High throughput no no
RING2_HUMAN [view interactions] High throughput no yes
BMI1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
CHC10_HUMAN [view interactions] High throughput no yes
CHCH2_HUMAN [view interactions] High throughput no yes
NDUF8_HUMAN [view interactions] High throughput no no
TRUB2_HUMAN [view interactions] High throughput no yes
NDKM_HUMAN [view interactions] High throughput no yes
OCAD1_HUMAN [view interactions] High throughput no yes
COQ8B_HUMAN [view interactions] High throughput no yes
NFAC2_HUMAN [view interactions] High throughput no yes
DPF3_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
MTMRB_HUMAN [view interactions] High throughput no no
ZN852_HUMAN [view interactions] High throughput no no
WASF1_HUMAN [view entry] [view interactions] High throughput yes yes
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
ZN629_HUMAN [view interactions] High throughput no no
ZSC20_HUMAN [view interactions] High throughput no yes
WASF3_HUMAN [view entry] [view interactions] High throughput yes yes
BRK1_HUMAN [view interactions] High throughput no no
MUC5B_HUMAN [view interactions] High throughput no no
WASF2_HUMAN [view entry] [view interactions] High throughput yes yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
GLCNE_HUMAN [view interactions] High throughput no yes
DPP9_HUMAN [view interactions] High throughput no yes
NCKP1_HUMAN [view entry] [view interactions] High throughput yes yes
BPIB1_HUMAN [view interactions] High throughput no no
ZN100_HUMAN [view interactions] High throughput no no
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
ZN624_HUMAN [view interactions] High throughput no yes
IGJ_HUMAN [view interactions] High throughput no no
ZKSC8_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
ZN598_HUMAN [view interactions] High throughput no no
HIF1N_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
MK06_HUMAN [view interactions] High throughput no yes
RMD5A_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
HIF1A_HUMAN [view interactions] High throughput no no
SOCS6_HUMAN [view interactions] High throughput no yes
MINY4_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
AMRA1_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
LYRIC_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
S15A3_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC3_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
BRD7_HUMAN [view interactions] High throughput no yes
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
RHG22_HUMAN [view entry] [view interactions] High throughput yes yes
PKHG2_HUMAN [view interactions] High throughput no no
CHM4C_HUMAN [view interactions] High throughput no yes
MD2L2_HUMAN [view interactions] High throughput no yes
BRD1_HUMAN [view interactions] High throughput no yes
BRPF3_HUMAN [view interactions] High throughput no yes
SP100_HUMAN [view interactions] High throughput no no
TRI33_HUMAN [view interactions] High throughput no yes
TRI66_HUMAN [view interactions] High throughput no yes
NMRL1_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
DNJB8_HUMAN [view interactions] High throughput no no
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
RIN3_HUMAN [view interactions] High throughput no yes
ISG15_HUMAN [view interactions] High throughput no no
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
DCAF8_HUMAN [view interactions] High throughput no yes
FZR1_HUMAN [view interactions] High throughput no no
WDR5_HUMAN [view interactions] High throughput no no
ZNF8_HUMAN [view interactions] High throughput no yes
ZN430_HUMAN [view interactions] High throughput no no
PLSI_HUMAN [view interactions] High throughput no no
ZNF92_HUMAN [view interactions] High throughput no no
SALL1_HUMAN [view interactions] High throughput no yes
ZN445_HUMAN [view interactions] High throughput no no
ZG16B_HUMAN [view interactions] High throughput no no
ZSCA2_HUMAN [view interactions] High throughput no yes
ZN768_HUMAN [view interactions] High throughput no yes
IPO8_HUMAN [view interactions] High throughput no no
CBWD1_HUMAN [view interactions] High throughput no yes
GTF2I_HUMAN [view interactions] High throughput no yes
ZN708_HUMAN [view interactions] High throughput no no
MDM2_HUMAN [view interactions] High throughput no yes
MCE1_HUMAN [view interactions] High throughput no yes
CCDC9_HUMAN [view interactions] High throughput no yes
VWA8_HUMAN [view interactions] High throughput no yes
ZN195_HUMAN [view interactions] High throughput no yes
SEN2_HUMAN [view interactions] High throughput no yes
ZN253_HUMAN [view interactions] High throughput no no
ZN320_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RIT1_HUMAN [view interactions] High throughput no yes
TOM70_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
SRSF5_HUMAN [view interactions] High throughput no yes
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
KDM1A_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
TIM13_HUMAN [view interactions] High throughput no yes
TOM40_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
TOM7_HUMAN [view interactions] High throughput no no
DAF_HUMAN [view interactions] High throughput no no
SFXN3_HUMAN [view entry] [view interactions] High throughput yes yes
ACAD9_HUMAN [view interactions] High throughput no yes
VAMP2_HUMAN [view entry] [view interactions] High throughput yes no
DCTN4_HUMAN [view entry] [view interactions] High throughput yes yes
CMC1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
BRAF_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
AP2A_HUMAN [view interactions] High throughput no no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
FTM_HUMAN [view interactions] High throughput no yes
CBX5_HUMAN [view interactions] High throughput no yes
TIM23_HUMAN [view interactions] High throughput no yes
TIM21_HUMAN [view interactions] High throughput no yes
HDAC6_HUMAN [view interactions] High throughput no yes
DNJA4_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
PR15A_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
IRAK1_HUMAN [view interactions] High throughput no yes
TOM22_HUMAN [view interactions] Computational no yes
MPPB_HUMAN [view interactions] Computational no yes
TIM10_HUMAN [view interactions] Computational no yes
MIA40_HUMAN [view interactions] Computational no yes
ATPB_HUMAN [view interactions] Computational no yes
TI17A_HUMAN [view interactions] Computational no yes
TIM9_HUMAN [view interactions] Computational no yes
GRPE1_HUMAN [view interactions] Computational no yes
TIM16_HUMAN [view entry] [view interactions] Computational yes no
GRPE2_HUMAN [view interactions] Computational no yes
DJC15_HUMAN [view interactions] Computational no no
ALR_HUMAN [view interactions] Computational no yes
SPT5H_HUMAN [view interactions] Computational no yes
GRP75_HUMAN [view entry] [view interactions] Computational yes yes
TIM8A_HUMAN [view interactions] Computational no yes
TOM20_HUMAN [view entry] [view interactions] Computational yes yes
TM40L_HUMAN [view entry] [view interactions] Computational yes yes
TIM44_HUMAN [view interactions] Computational no yes
SAM50_HUMAN [view entry] [view interactions] Computational yes yes
TIM14_HUMAN [view entry] [view interactions] Computational yes yes
MPPA_HUMAN [view interactions] Computational no yes
TIM22_HUMAN [view interactions] Computational no no
ROMO1_HUMAN [view interactions] Computational no yes