ABI2_HUMAN
Evidence for PS localization
Functions
Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (PubMed). Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (PubMed, PubMed, PubMed). Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain . In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth . Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface . Also required for nascent adherens junction assembly in epithelial cells (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABI2_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 23.1579 | 4 | no |
| GO:0043168 | anion binding | 21.0526 | 4 | no |
| GO:0019900 | kinase binding | 18.9474 | 4 | yes |
| GO:0017124 | SH3 domain binding | 13.6842 | 4 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 11.5789 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 10.5263 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABI2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.1053 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 55.7895 | 4 | yes |
| GO:0006996 | organelle organization | 49.4737 | 4 | yes |
| GO:0022607 | cellular component assembly | 47.3684 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 46.3158 | 4 | no |
| GO:0010646 | regulation of cell communication | 45.2632 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 45.2632 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.2632 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.0526 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 41.0526 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.9474 | 4 | no |
| GO:0008104 | protein localization | 37.8947 | 4 | no |
| GO:0030030 | cell projection organization | 37.8947 | 4 | no |
| GO:0007010 | cytoskeleton organization | 34.7368 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 34.7368 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 34.7368 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 34.7368 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.7368 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.6842 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.6842 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.6842 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 33.6842 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.6842 | 6 | no |
| GO:0051049 | regulation of transport | 32.6316 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.6316 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.5263 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 30.5263 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 30.5263 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 29.4737 | 6 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 29.4737 | 5 | no |
| GO:0023056 | positive regulation of signaling | 29.4737 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 28.4211 | 5 | yes |
| GO:0097435 | supramolecular fiber organization | 28.4211 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 28.4211 | 6 | yes |
| GO:0009967 | positive regulation of signal transduction | 27.3684 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.3158 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.3158 | 4 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 25.2632 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 25.2632 | 4 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 25.2632 | 5 | yes |
| GO:0007015 | actin filament organization | 24.2105 | 5 | yes |
| GO:0141124 | intracellular signaling cassette | 24.2105 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.1579 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.1579 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.1579 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.1579 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 23.1579 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 23.1579 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 23.1579 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 23.1579 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 23.1579 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 23.1579 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.1053 | 4 | no |
| GO:0051050 | positive regulation of transport | 22.1053 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.1053 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 22.1053 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.1053 | 6 | no |
| GO:0110053 | regulation of actin filament organization | 22.1053 | 6 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 22.1053 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.1053 | 7 | no |
| GO:0010648 | negative regulation of cell communication | 21.0526 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.0526 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.0526 | 5 | no |
| GO:2000145 | regulation of cell motility | 21.0526 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 21.0526 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 21.0526 | 6 | no |
| GO:0036211 | protein modification process | 20.0000 | 4 | yes |
| GO:0043412 | macromolecule modification | 20.0000 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 18.9474 | 7 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 18.9474 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 18.9474 | 6 | yes |
| GO:0031346 | positive regulation of cell projection organization | 17.8947 | 6 | yes |
| GO:0007264 | small GTPase-mediated signal transduction | 16.8421 | 5 | yes |
| GO:0034330 | cell junction organization | 16.8421 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 13.6842 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 13.6842 | 5 | yes |
| GO:0060491 | regulation of cell projection assembly | 13.6842 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 13.6842 | 6 | yes |
| GO:0016601 | Rac protein signal transduction | 11.5789 | 6 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 11.5789 | 6 | yes |
| GO:0008154 | actin polymerization or depolymerization | 10.5263 | 6 | yes |
| GO:0034329 | cell junction assembly | 10.5263 | 5 | yes |
| GO:0010591 | regulation of lamellipodium assembly | 9.4737 | 7 | yes |
| GO:0099175 | regulation of postsynapse organization | 9.4737 | 6 | yes |
| GO:1902743 | regulation of lamellipodium organization | 9.4737 | 7 | yes |
| GO:0006468 | protein phosphorylation | 8.4211 | 5 | yes |
| GO:0010592 | positive regulation of lamellipodium assembly | 8.4211 | 7 | yes |
| GO:0016310 | phosphorylation | 8.4211 | 5 | yes |
| GO:0045216 | cell-cell junction organization | 8.4211 | 5 | yes |
| GO:1902745 | positive regulation of lamellipodium organization | 8.4211 | 7 | yes |
| GO:0007043 | cell-cell junction assembly | 7.3684 | 6 | yes |
| GO:0018193 | peptidyl-amino acid modification | 7.3684 | 5 | yes |
| GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation | 7.3684 | 8 | yes |
| GO:0051125 | regulation of actin nucleation | 7.3684 | 7 | yes |
| GO:0051127 | positive regulation of actin nucleation | 7.3684 | 7 | yes |
| GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation | 7.3684 | 8 | yes |
| GO:0034332 | adherens junction organization | 6.3158 | 6 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 6.3158 | 5 | yes |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 5.2632 | 6 | yes |
| GO:0018212 | peptidyl-tyrosine modification | 5.2632 | 6 | yes |
| GO:0034333 | adherens junction assembly | 5.2632 | 7 | yes |
| GO:0007399 | nervous system development | 4.2105 | 4 | yes |
| GO:0045186 | zonula adherens assembly | 2.1053 | 8 | yes |
| GO:0070309 | lens fiber cell morphogenesis | 2.1053 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ADA19_HUMAN | [view interactions] | Low throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CSKI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRK1_HUMAN | [view interactions] | Low throughput | no | no |
| PCD10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRI32_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN688_HUMAN | [view interactions] | High throughput | no | yes |
| ATOSB_HUMAN | [view interactions] | High throughput | no | yes |
| AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| LMO3_HUMAN | [view interactions] | High throughput | no | no |
| PRDM6_HUMAN | [view interactions] | High throughput | no | no |
| MED29_HUMAN | [view interactions] | High throughput | no | no |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZMY12_HUMAN | [view interactions] | High throughput | no | no |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEGN_HUMAN | [view interactions] | High throughput | no | no |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM28_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FXL19_HUMAN | [view interactions] | High throughput | no | no |
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| RSP14_HUMAN | [view interactions] | High throughput | no | no |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| LENG1_HUMAN | [view interactions] | High throughput | no | no |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| LHX3_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| RASD1_HUMAN | [view interactions] | High throughput | no | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHL5_HUMAN | [view interactions] | High throughput | no | no |
| PHF1_HUMAN | [view interactions] | High throughput | no | yes |
| COLI_HUMAN | [view interactions] | High throughput | no | no |
| IN80B_HUMAN | [view interactions] | High throughput | no | no |
| AIRIM_HUMAN | [view interactions] | High throughput | no | yes |
| DNAI7_HUMAN | [view interactions] | High throughput | no | no |
| VINEX_HUMAN | [view interactions] | High throughput | no | no |
| MYOG_HUMAN | [view interactions] | High throughput | no | no |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| KRT36_HUMAN | [view interactions] | High throughput | no | no |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKAP_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| ES8L1_HUMAN | [view interactions] | High throughput | no | no |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED10_HUMAN | [view interactions] | High throughput | no | no |
| EGR4_HUMAN | [view interactions] | High throughput | no | yes |
| COG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC115_HUMAN | [view interactions] | High throughput | no | no |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD017_HUMAN | [view interactions] | High throughput | no | no |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CA216_HUMAN | [view interactions] | High throughput | no | yes |
| LMO4_HUMAN | [view interactions] | High throughput | no | yes |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| BIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PRD14_HUMAN | [view interactions] | High throughput | no | no |
| CC74B_HUMAN | [view interactions] | High throughput | no | no |
| HHEX_HUMAN | [view interactions] | High throughput | no | no |
| CENPH_HUMAN | [view interactions] | High throughput | no | yes |
| RABX5_HUMAN | [view interactions] | High throughput | no | no |
| SLAP1_HUMAN | [view interactions] | High throughput | no | yes |
| F161B_HUMAN | [view interactions] | High throughput | no | yes |
| BAG4_HUMAN | [view interactions] | High throughput | no | yes |
| HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
| RUSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED11_HUMAN | [view interactions] | High throughput | no | no |
| LHX8_HUMAN | [view interactions] | High throughput | no | no |
| SNX7_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFASC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| ZN474_HUMAN | [view interactions] | High throughput | no | no |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| MYOZ3_HUMAN | [view interactions] | High throughput | no | no |
| CEP57_HUMAN | [view interactions] | High throughput | no | yes |
| RBTN1_HUMAN | [view interactions] | High throughput | no | no |
| ATP23_HUMAN | [view interactions] | High throughput | no | yes |
| K1C24_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LEG9B_HUMAN | [view interactions] | High throughput | no | no |
| K2C75_HUMAN | [view interactions] | High throughput | no | no |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| PWP2B_HUMAN | [view interactions] | High throughput | no | yes |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| ABLM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| TRI72_HUMAN | [view interactions] | High throughput | no | no |
| RPP25_HUMAN | [view interactions] | High throughput | no | yes |
| STX19_HUMAN | [view interactions] | High throughput | no | yes |
| SNX18_HUMAN | [view interactions] | High throughput | no | no |
| MOFA1_HUMAN | [view interactions] | High throughput | no | yes |
| TRIMM_HUMAN | [view interactions] | High throughput | no | no |
| GGN_HUMAN | [view interactions] | High throughput | no | no |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUED1_HUMAN | [view interactions] | High throughput | no | yes |
| WASH1_HUMAN | [view interactions] | High throughput | no | yes |
| FX4L1_HUMAN | [view interactions] | High throughput | no | no |
| ZFP90_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| K1C14_HUMAN | [view interactions] | High throughput | no | no |
| FAM9C_HUMAN | [view interactions] | High throughput | no | no |
| PKHN1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S5_HUMAN | [view interactions] | High throughput | no | yes |
| ACTMP_HUMAN | [view interactions] | High throughput | no | no |
| INCA1_HUMAN | [view interactions] | High throughput | no | no |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SESQ1_HUMAN | [view interactions] | High throughput | no | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGA1_HUMAN | [view interactions] | High throughput | no | no |
| OOEP_HUMAN | [view interactions] | High throughput | no | no |
| GPAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PR20E_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNPS1_HUMAN | [view interactions] | High throughput | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CMI2B_HUMAN | [view interactions] | High throughput | no | no |
| CT202_HUMAN | [view interactions] | High throughput | no | no |
| GA2L2_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN511_HUMAN | [view interactions] | High throughput | no | yes |
| UBX11_HUMAN | [view interactions] | High throughput | no | yes |
| LHX4_HUMAN | [view interactions] | High throughput | no | no |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL3_HUMAN | [view interactions] | High throughput | no | yes |
| NCKPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| AMZ1_HUMAN | [view interactions] | High throughput | no | no |
| CBLC_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBR3_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| SIKE1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHS_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IHO1_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DP13B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP37C_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| WIPF1_HUMAN | [view interactions] | High throughput | no | no |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBTN2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| PTK7_HUMAN | [view interactions] | High throughput | no | yes |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| TLE5_HUMAN | [view interactions] | High throughput | no | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARGN_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| GCC1_HUMAN | [view interactions] | High throughput | no | yes |
| MR1L1_HUMAN | [view interactions] | High throughput | no | no |
| PRAM_HUMAN | [view interactions] | High throughput | no | no |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| ARMC7_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RM44_HUMAN | [view interactions] | High throughput | no | yes |
| C102B_HUMAN | [view interactions] | High throughput | no | yes |
| CRX_HUMAN | [view interactions] | High throughput | no | no |
| EFS_HUMAN | [view interactions] | High throughput | no | no |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| KT33B_HUMAN | [view interactions] | High throughput | no | no |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| SYVM_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C13_HUMAN | [view interactions] | High throughput | no | no |
| K1C20_HUMAN | [view interactions] | High throughput | no | no |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PCD17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |