ABI2_HUMAN
Evidence for PS localization
Functions
Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (PubMed). Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (PubMed, PubMed, PubMed). Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain . In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth . Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface . Also required for nascent adherens junction assembly in epithelial cells (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABI2_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 23.5294 | 4 | no |
| GO:0019900 | kinase binding | 20.0000 | 4 | yes |
| GO:0017124 | SH3 domain binding | 11.7647 | 4 | yes |
| GO:0044389 | ubiquitin-like protein ligase binding | 11.7647 | 4 | yes |
| GO:0031625 | ubiquitin protein ligase binding | 10.5882 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABI2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.3529 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 55.2941 | 4 | yes |
| GO:0006996 | organelle organization | 51.7647 | 4 | yes |
| GO:0022607 | cellular component assembly | 48.2353 | 4 | yes |
| GO:0010646 | regulation of cell communication | 48.2353 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.8824 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 44.7059 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.7059 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.5294 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.3529 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 41.1765 | 4 | no |
| GO:0008104 | protein localization | 40.0000 | 4 | no |
| GO:0007010 | cytoskeleton organization | 38.8235 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 38.8235 | 4 | no |
| GO:0033043 | regulation of organelle organization | 37.6471 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 35.2941 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 35.2941 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.2941 | 5 | no |
| GO:0030030 | cell projection organization | 35.2941 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 34.1176 | 6 | yes |
| GO:0010468 | regulation of gene expression | 32.9412 | 5 | no |
| GO:0051049 | regulation of transport | 32.9412 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.7647 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 31.7647 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 31.7647 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 31.7647 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.5882 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 29.4118 | 5 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 29.4118 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 29.4118 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.4118 | 6 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 28.2353 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 28.2353 | 5 | no |
| GO:0023056 | positive regulation of signaling | 28.2353 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 28.2353 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 28.2353 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 27.0588 | 5 | yes |
| GO:0097435 | supramolecular fiber organization | 25.8824 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 25.8824 | 4 | no |
| GO:0071702 | organic substance transport | 25.8824 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 25.8824 | 5 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 24.7059 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 24.7059 | 4 | no |
| GO:0015031 | protein transport | 24.7059 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.7059 | 5 | no |
| GO:0071705 | nitrogen compound transport | 24.7059 | 4 | no |
| GO:0007015 | actin filament organization | 23.5294 | 5 | yes |
| GO:0110053 | regulation of actin filament organization | 23.5294 | 6 | yes |
| GO:0009892 | negative regulation of metabolic process | 23.5294 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 23.5294 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.5294 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.5294 | 5 | no |
| GO:0010638 | positive regulation of organelle organization | 22.3529 | 6 | yes |
| GO:0036211 | protein modification process | 22.3529 | 4 | yes |
| GO:0043412 | macromolecule modification | 22.3529 | 4 | yes |
| GO:0051050 | positive regulation of transport | 22.3529 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.3529 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.3529 | 6 | no |
| GO:0051495 | positive regulation of cytoskeleton organization | 21.1765 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 21.1765 | 6 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 21.1765 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.1765 | 5 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 21.1765 | 7 | no |
| GO:2000026 | regulation of multicellular organismal development | 21.1765 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.1765 | 6 | no |
| GO:0030031 | cell projection assembly | 21.1765 | 5 | no |
| GO:0031399 | regulation of protein modification process | 21.1765 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 21.1765 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 18.8235 | 7 | yes |
| GO:0031346 | positive regulation of cell projection organization | 18.8235 | 6 | yes |
| GO:0034330 | cell junction organization | 18.8235 | 4 | yes |
| GO:0007264 | small GTPase mediated signal transduction | 17.6471 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 16.4706 | 4 | yes |
| GO:0007265 | Ras protein signal transduction | 15.2941 | 5 | yes |
| GO:0060491 | regulation of cell projection assembly | 15.2941 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 15.2941 | 6 | yes |
| GO:0050807 | regulation of synapse organization | 12.9412 | 5 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 12.9412 | 6 | yes |
| GO:0016310 | phosphorylation | 11.7647 | 5 | yes |
| GO:0016601 | Rac protein signal transduction | 11.7647 | 6 | yes |
| GO:0034329 | cell junction assembly | 11.7647 | 5 | yes |
| GO:0006468 | protein phosphorylation | 10.5882 | 5 | yes |
| GO:0008154 | actin polymerization or depolymerization | 10.5882 | 6 | yes |
| GO:0010591 | regulation of lamellipodium assembly | 10.5882 | 7 | yes |
| GO:0018193 | peptidyl-amino acid modification | 10.5882 | 5 | yes |
| GO:1902743 | regulation of lamellipodium organization | 10.5882 | 7 | yes |
| GO:0010592 | positive regulation of lamellipodium assembly | 9.4118 | 7 | yes |
| GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation | 9.4118 | 8 | yes |
| GO:0045216 | cell-cell junction organization | 9.4118 | 5 | yes |
| GO:0051125 | regulation of actin nucleation | 9.4118 | 7 | yes |
| GO:0051127 | positive regulation of actin nucleation | 9.4118 | 7 | yes |
| GO:1902745 | positive regulation of lamellipodium organization | 9.4118 | 7 | yes |
| GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation | 9.4118 | 8 | yes |
| GO:0007043 | cell-cell junction assembly | 8.2353 | 6 | yes |
| GO:0034332 | adherens junction organization | 7.0588 | 6 | yes |
| GO:0061001 | regulation of dendritic spine morphogenesis | 7.0588 | 5 | yes |
| GO:0099175 | regulation of postsynapse organization | 7.0588 | 6 | yes |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 5.8824 | 6 | yes |
| GO:0018212 | peptidyl-tyrosine modification | 5.8824 | 6 | yes |
| GO:0034333 | adherens junction assembly | 5.8824 | 7 | yes |
| GO:0000904 | cell morphogenesis involved in differentiation | 4.7059 | 4 | yes |
| GO:0007399 | nervous system development | 3.5294 | 4 | yes |
| GO:0045186 | zonula adherens assembly | 2.3529 | 8 | yes |
| GO:0070309 | lens fiber cell morphogenesis | 2.3529 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ABI2_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 2.3529 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 2.3529 | 5 | no |
| DOID:114 | heart disease | 2.3529 | 3 | no |
| DOID:1443 | cerebral degeneration | 2.3529 | 5 | no |
| DOID:331 | central nervous system disease | 2.3529 | 3 | no |
| DOID:936 | brain disease | 2.3529 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ADA19_HUMAN | [view interactions] | Low throughput | no | no |
| CSKI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRK1_HUMAN | [view interactions] | Low throughput | no | no |
| PCD10_HUMAN | [view interactions] | Low throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TRI32_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AMZ1_HUMAN | [view interactions] | High throughput | no | no |
| CBLC_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBR3_HUMAN | [view interactions] | High throughput | no | yes |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG12_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FSD2_HUMAN | [view interactions] | High throughput | no | no |
| SIKE1_HUMAN | [view interactions] | High throughput | no | yes |
| KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHS_HUMAN | [view interactions] | High throughput | no | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IHO1_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| KHDR1_HUMAN | [view interactions] | High throughput | no | yes |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DP13B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VP37C_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIPF1_HUMAN | [view interactions] | High throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBTN2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIF_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| TLE5_HUMAN | [view interactions] | High throughput | no | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARGN_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| GCC1_HUMAN | [view interactions] | High throughput | no | yes |
| MR1L1_HUMAN | [view interactions] | High throughput | no | no |
| PRAM_HUMAN | [view interactions] | High throughput | no | no |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| ARMC7_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RM44_HUMAN | [view interactions] | High throughput | no | yes |
| C102B_HUMAN | [view interactions] | High throughput | no | yes |
| CRX_HUMAN | [view interactions] | High throughput | no | no |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| EFS_HUMAN | [view interactions] | High throughput | no | no |
| KT33B_HUMAN | [view interactions] | High throughput | no | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| BL1S6_HUMAN | [view interactions] | High throughput | no | yes |
| TFP11_HUMAN | [view interactions] | High throughput | no | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1C19_HUMAN | [view interactions] | High throughput | no | no |
| K1C20_HUMAN | [view interactions] | High throughput | no | no |
| K1C13_HUMAN | [view interactions] | High throughput | no | no |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| SYVM_HUMAN | [view interactions] | High throughput | no | yes |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PCD17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN688_HUMAN | [view interactions] | High throughput | no | yes |
| F214B_HUMAN | [view interactions] | High throughput | no | yes |
| AKP8L_HUMAN | [view interactions] | High throughput | no | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| LMO3_HUMAN | [view interactions] | High throughput | no | no |
| PRDM6_HUMAN | [view interactions] | High throughput | no | no |
| MED29_HUMAN | [view interactions] | High throughput | no | no |
| ANS1A_HUMAN | [view interactions] | High throughput | no | yes |
| AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| ZMY12_HUMAN | [view interactions] | High throughput | no | no |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| SEGN_HUMAN | [view interactions] | High throughput | no | no |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM28_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FXL19_HUMAN | [view interactions] | High throughput | no | no |
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| RSP14_HUMAN | [view interactions] | High throughput | no | no |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MS18B_HUMAN | [view interactions] | High throughput | no | no |
| LENG1_HUMAN | [view interactions] | High throughput | no | no |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| LHX3_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| RASD1_HUMAN | [view interactions] | High throughput | no | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FHL5_HUMAN | [view interactions] | High throughput | no | no |
| PHF1_HUMAN | [view interactions] | High throughput | no | yes |
| COLI_HUMAN | [view interactions] | High throughput | no | no |
| IN80B_HUMAN | [view interactions] | High throughput | no | no |
| CA109_HUMAN | [view interactions] | High throughput | no | yes |
| DNAI7_HUMAN | [view interactions] | High throughput | no | no |
| VINEX_HUMAN | [view interactions] | High throughput | no | no |
| MYOG_HUMAN | [view interactions] | High throughput | no | no |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| KRT36_HUMAN | [view interactions] | High throughput | no | no |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKAP_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| ES8L1_HUMAN | [view interactions] | High throughput | no | no |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED10_HUMAN | [view interactions] | High throughput | no | no |
| EGR4_HUMAN | [view interactions] | High throughput | no | yes |
| COG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC115_HUMAN | [view interactions] | High throughput | no | no |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD017_HUMAN | [view interactions] | High throughput | no | no |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CA216_HUMAN | [view interactions] | High throughput | no | yes |
| LMO4_HUMAN | [view interactions] | High throughput | no | yes |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAPN_HUMAN | [view interactions] | High throughput | no | yes |
| BIN3_HUMAN | [view interactions] | High throughput | no | yes |
| PRD14_HUMAN | [view interactions] | High throughput | no | no |
| CC74B_HUMAN | [view interactions] | High throughput | no | no |
| HHEX_HUMAN | [view interactions] | High throughput | no | no |
| CENPH_HUMAN | [view interactions] | High throughput | no | yes |
| RABX5_HUMAN | [view interactions] | High throughput | no | no |
| SLAP1_HUMAN | [view interactions] | High throughput | no | yes |
| F161B_HUMAN | [view interactions] | High throughput | no | yes |
| BAG4_HUMAN | [view interactions] | High throughput | no | yes |
| HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
| RUSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VPS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED11_HUMAN | [view interactions] | High throughput | no | no |
| LHX8_HUMAN | [view interactions] | High throughput | no | no |
| SNX7_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFASC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| ZN474_HUMAN | [view interactions] | High throughput | no | no |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| MYOZ3_HUMAN | [view interactions] | High throughput | no | no |
| CEP57_HUMAN | [view interactions] | High throughput | no | yes |
| RBTN1_HUMAN | [view interactions] | High throughput | no | no |
| ATP23_HUMAN | [view interactions] | High throughput | no | yes |
| K1C24_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LEG9B_HUMAN | [view interactions] | High throughput | no | no |
| K2C75_HUMAN | [view interactions] | High throughput | no | no |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C27_HUMAN | [view interactions] | High throughput | no | no |
| PWP2B_HUMAN | [view interactions] | High throughput | no | yes |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| ABLM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| TRI72_HUMAN | [view interactions] | High throughput | no | no |
| RPP25_HUMAN | [view interactions] | High throughput | no | yes |
| STX19_HUMAN | [view interactions] | High throughput | no | yes |
| SNX18_HUMAN | [view interactions] | High throughput | no | no |
| MOFA1_HUMAN | [view interactions] | High throughput | no | yes |
| TRIMM_HUMAN | [view interactions] | High throughput | no | no |
| GGN_HUMAN | [view interactions] | High throughput | no | no |
| PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUED1_HUMAN | [view interactions] | High throughput | no | yes |
| WASH1_HUMAN | [view interactions] | High throughput | no | yes |
| FX4L1_HUMAN | [view interactions] | High throughput | no | no |
| ZFP90_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| K1C14_HUMAN | [view interactions] | High throughput | no | no |
| FAM9C_HUMAN | [view interactions] | High throughput | no | no |
| PKHN1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S5_HUMAN | [view interactions] | High throughput | no | yes |
| CS054_HUMAN | [view interactions] | High throughput | no | no |
| INCA1_HUMAN | [view interactions] | High throughput | no | no |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SESQ1_HUMAN | [view interactions] | High throughput | no | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGA1_HUMAN | [view interactions] | High throughput | no | no |
| OOEP_HUMAN | [view interactions] | High throughput | no | no |
| GPAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PR20E_HUMAN | [view interactions] | High throughput | no | no |
| INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNPS1_HUMAN | [view interactions] | High throughput | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F166B_HUMAN | [view interactions] | High throughput | no | no |
| CT202_HUMAN | [view interactions] | High throughput | no | no |
| GA2L2_HUMAN | [view interactions] | High throughput | no | no |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN511_HUMAN | [view interactions] | High throughput | no | yes |
| UBX11_HUMAN | [view interactions] | High throughput | no | yes |
| LHX4_HUMAN | [view interactions] | High throughput | no | no |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| K1522_HUMAN | [view interactions] | High throughput | no | yes |
| NCKPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |