ABI3_HUMAN
Evidence for PS localization
Functions
May inhibit tumor metastasis . In vitro, reduces cell motility. [View more on UniProt]
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 37%
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Close ✖
ABI3_HUMAN has binary interactions with 27 proteins
Isoforms
Interacting regions
Canonical [ABI3_HUMAN]
Isoform [Q9P2A4-2] alignment
Isoform [I3L3W4] alignment
Isoform [I3L1X2] alignment
LOADING 45%
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABI3_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 32.1429 | 4 | yes |
| GO:0017124 | SH3 domain binding | 28.5714 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABI3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 64.2857 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 64.2857 | 4 | yes |
| GO:0006996 | organelle organization | 50.0000 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 50.0000 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 46.4286 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 46.4286 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 46.4286 | 4 | no |
| GO:0010646 | regulation of cell communication | 46.4286 | 4 | no |
| GO:0007010 | cytoskeleton organization | 42.8571 | 5 | yes |
| GO:0022607 | cellular component assembly | 42.8571 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 39.2857 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 39.2857 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 39.2857 | 6 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 39.2857 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 39.2857 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 39.2857 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 39.2857 | 6 | no |
| GO:0110053 | regulation of actin filament organization | 39.2857 | 6 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 39.2857 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 32.1429 | 4 | yes |
| GO:0030030 | cell projection organization | 32.1429 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 28.5714 | 7 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 28.5714 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 28.5714 | 5 | yes |
| GO:0010638 | positive regulation of organelle organization | 28.5714 | 6 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| 3BP1_HUMAN | [view interactions] | High throughput | no | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGTR1_HUMAN | [view interactions] | High throughput | no | no |
| ARMC7_HUMAN | [view interactions] | High throughput | no | yes |
| BFSP2_HUMAN | [view interactions] | High throughput | no | no |
| BI2L2_HUMAN | [view interactions] | High throughput | no | yes |
| BL1S5_HUMAN | [view interactions] | High throughput | no | yes |
| C170L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| CEP44_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP2_HUMAN | [view interactions] | High throughput | no | no |
| CYFP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DESI1_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| EMIL1_HUMAN | [view interactions] | High throughput | no | no |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EVL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F124B_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |