SNP23_HUMAN
Evidence for PS localization
Functions
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNP23_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 38.1579 | 4 | no |
| GO:0000166 | nucleotide binding | 36.8421 | 4 | no |
| GO:0017076 | purine nucleotide binding | 36.8421 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 36.8421 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 36.8421 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 30.2632 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 30.2632 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 30.2632 | 6 | no |
| GO:0003924 | GTPase activity | 26.3158 | 7 | no |
| GO:0005525 | GTP binding | 25.0000 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 25.0000 | 6 | no |
| GO:0032561 | guanyl ribonucleotide binding | 25.0000 | 5 | no |
| GO:0019900 | kinase binding | 23.6842 | 4 | no |
| GO:0019905 | syntaxin binding | 15.7895 | 4 | yes |
| GO:0017075 | syntaxin-1 binding | 9.2105 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNP23_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 68.4211 | 4 | no |
| GO:0008104 | protein localization | 63.1579 | 4 | yes |
| GO:0071702 | organic substance transport | 53.9474 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 50.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0006996 | organelle organization | 46.0526 | 4 | yes |
| GO:0015031 | protein transport | 46.0526 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 46.0526 | 4 | no |
| GO:0010646 | regulation of cell communication | 43.4211 | 4 | no |
| GO:0022607 | cellular component assembly | 42.1053 | 4 | yes |
| GO:0051049 | regulation of transport | 42.1053 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 42.1053 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 40.7895 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 39.4737 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.1579 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 36.8421 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 36.8421 | 4 | no |
| GO:0009966 | regulation of signal transduction | 35.5263 | 4 | no |
| GO:0060341 | regulation of cellular localization | 34.2105 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 34.2105 | 4 | no |
| GO:0010468 | regulation of gene expression | 34.2105 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 34.2105 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 34.2105 | 5 | no |
| GO:0023056 | positive regulation of signaling | 32.8947 | 4 | no |
| GO:0032880 | regulation of protein localization | 32.8947 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 31.5789 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.5789 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 31.5789 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.2632 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.2632 | 5 | no |
| GO:0006886 | intracellular protein transport | 30.2632 | 4 | no |
| GO:0061024 | membrane organization | 26.3158 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 26.3158 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.3158 | 5 | no |
| GO:2000145 | regulation of cell motility | 26.3158 | 4 | no |
| GO:0071310 | cellular response to organic substance | 25.0000 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.0000 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.0000 | 6 | no |
| GO:0051050 | positive regulation of transport | 23.6842 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 23.6842 | 5 | no |
| GO:0030334 | regulation of cell migration | 23.6842 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.6842 | 6 | no |
| GO:0016050 | vesicle organization | 22.3684 | 5 | yes |
| GO:0046903 | secretion | 22.3684 | 4 | yes |
| GO:0051046 | regulation of secretion | 22.3684 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 22.3684 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 22.3684 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.3684 | 6 | no |
| GO:0141124 | intracellular signaling cassette | 22.3684 | 4 | no |
| GO:0043933 | protein-containing complex organization | 21.0526 | 4 | yes |
| GO:0030030 | cell projection organization | 21.0526 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 21.0526 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.0526 | 5 | no |
| GO:0061025 | membrane fusion | 18.4211 | 5 | yes |
| GO:0048284 | organelle fusion | 17.1053 | 5 | yes |
| GO:0065003 | protein-containing complex assembly | 17.1053 | 5 | yes |
| GO:0006906 | vesicle fusion | 15.7895 | 6 | yes |
| GO:0090174 | organelle membrane fusion | 15.7895 | 6 | yes |
| GO:0006892 | post-Golgi vesicle-mediated transport | 10.5263 | 4 | yes |
| GO:0023061 | signal release | 10.5263 | 4 | yes |
| GO:0009914 | hormone transport | 7.8947 | 4 | yes |
| GO:0046879 | hormone secretion | 7.8947 | 5 | yes |
| GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane | 6.5789 | 4 | yes |
| GO:0048499 | synaptic vesicle membrane organization | 6.5789 | 5 | yes |
| GO:0001821 | histamine secretion | 3.9474 | 5 | yes |
| GO:0002441 | histamine secretion involved in inflammatory response | 3.9474 | 6 | yes |
| GO:0051608 | histamine transport | 3.9474 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KINH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCAM1_HUMAN | [view interactions] | Low throughput | no | no |
| SCAM2_HUMAN | [view interactions] | Low throughput | no | no |
| STX6_HUMAN | [view interactions] | Low throughput | no | yes |
| IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNTG1_HUMAN | [view interactions] | Low throughput | no | no |
| STXB5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX11_HUMAN | [view interactions] | Low throughput | no | yes |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
| SCAM5_HUMAN | [view interactions] | Low throughput | no | yes |
| STX17_HUMAN | [view interactions] | Low throughput | no | yes |
| CFTR_HUMAN | [view interactions] | Low throughput | no | no |
| ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNAPN_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP7_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| STX4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VAMP8_HUMAN | [view interactions] | Low throughput | no | no |
| TLK1_HUMAN | [view interactions] | Low throughput | no | yes |
| SEGN_HUMAN | [view interactions] | Low throughput | no | no |
| STXB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX2_HUMAN | [view interactions] | Low throughput | no | no |
| STX18_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP97_HUMAN | [view interactions] | High throughput | no | yes |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX19_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| STXB6_HUMAN | [view interactions] | High throughput | no | yes |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXB7_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| WWP1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| CLD4_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| MIDN_HUMAN | [view interactions] | High throughput | no | no |
| RECQ1_HUMAN | [view interactions] | High throughput | no | yes |
| PTAR1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| ELOF1_HUMAN | [view interactions] | High throughput | no | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF2_HUMAN | [view interactions] | High throughput | no | yes |
| SAP_HUMAN | [view interactions] | High throughput | no | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| FAM3C_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS12B_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LMAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| ARL4C_HUMAN | [view interactions] | High throughput | no | yes |
| ARL5A_HUMAN | [view interactions] | High throughput | no | yes |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| ARL15_HUMAN | [view interactions] | High throughput | no | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| TP4A2_HUMAN | [view interactions] | High throughput | no | yes |
| MOB2_HUMAN | [view interactions] | High throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MUC18_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| WASH2_HUMAN | [view interactions] | High throughput | no | no |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P20L1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC30_HUMAN | [view interactions] | High throughput | no | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UT2_HUMAN | [view interactions] | High throughput | no | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| CEBPD_HUMAN | [view interactions] | High throughput | no | no |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| ZDH17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |