SNP23_HUMAN
Evidence for PS localization
Functions
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNP23_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 33.7349 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 33.7349 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 33.7349 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 28.9157 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 28.9157 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 28.9157 | 6 | no |
| GO:0019900 | kinase binding | 26.5060 | 4 | no |
| GO:0003924 | GTPase activity | 26.5060 | 7 | no |
| GO:0005525 | GTP binding | 25.3012 | 5 | no |
| GO:0019001 | guanyl nucleotide binding | 25.3012 | 5 | no |
| GO:0032561 | guanyl ribonucleotide binding | 25.3012 | 5 | no |
| GO:0019901 | protein kinase binding | 22.8916 | 5 | no |
| GO:0019905 | syntaxin binding | 20.4819 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNP23_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 66.2651 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 62.6506 | 4 | no |
| GO:0071702 | organic substance transport | 60.2410 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 59.0361 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 57.8313 | 4 | yes |
| GO:0015031 | protein transport | 53.0120 | 4 | yes |
| GO:0006996 | organelle organization | 51.8072 | 4 | yes |
| GO:0051049 | regulation of transport | 51.8072 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 48.1928 | 4 | no |
| GO:0022607 | cellular component assembly | 44.5783 | 4 | yes |
| GO:0010646 | regulation of cell communication | 44.5783 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 38.5542 | 4 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 38.5542 | 4 | no |
| GO:0046903 | secretion | 37.3494 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 37.3494 | 4 | no |
| GO:0061024 | membrane organization | 34.9398 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 34.9398 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 34.9398 | 4 | no |
| GO:0006887 | exocytosis | 33.7349 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 32.5301 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 32.5301 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.5301 | 5 | no |
| GO:0023056 | positive regulation of signaling | 31.3253 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 31.3253 | 4 | no |
| GO:0016050 | vesicle organization | 30.1205 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 30.1205 | 4 | no |
| GO:0071310 | cellular response to organic substance | 30.1205 | 4 | no |
| GO:0051046 | regulation of secretion | 30.1205 | 5 | no |
| GO:1903530 | regulation of secretion by cell | 30.1205 | 4 | no |
| GO:0032880 | regulation of protein localization | 28.9157 | 5 | no |
| GO:0033043 | regulation of organelle organization | 28.9157 | 5 | no |
| GO:0006886 | intracellular protein transport | 28.9157 | 4 | no |
| GO:0009966 | regulation of signal transduction | 28.9157 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.9157 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.7108 | 5 | no |
| GO:0051050 | positive regulation of transport | 27.7108 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 27.7108 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 27.7108 | 5 | no |
| GO:0010468 | regulation of gene expression | 26.5060 | 5 | no |
| GO:0061025 | membrane fusion | 25.3012 | 5 | yes |
| GO:0030030 | cell projection organization | 25.3012 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 24.0964 | 5 | no |
| GO:0017157 | regulation of exocytosis | 24.0964 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.8916 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.8916 | 4 | no |
| GO:0009894 | regulation of catabolic process | 22.8916 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.8916 | 6 | no |
| GO:0006906 | vesicle fusion | 21.6867 | 6 | yes |
| GO:0048193 | Golgi vesicle transport | 21.6867 | 5 | yes |
| GO:0048284 | organelle fusion | 21.6867 | 5 | yes |
| GO:0090174 | organelle membrane fusion | 21.6867 | 6 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 21.6867 | 5 | no |
| GO:0072657 | protein localization to membrane | 21.6867 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.4819 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.4819 | 6 | no |
| GO:0048278 | vesicle docking | 20.4819 | 4 | no |
| GO:0043933 | protein-containing complex organization | 19.2771 | 4 | yes |
| GO:0006892 | post-Golgi vesicle-mediated transport | 16.8675 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 15.6627 | 5 | yes |
| GO:0023061 | signal release | 14.4578 | 4 | yes |
| GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane | 8.4337 | 4 | yes |
| GO:0048499 | synaptic vesicle membrane organization | 8.4337 | 5 | yes |
| GO:0006811 | ion transport | 7.2289 | 4 | yes |
| GO:0009914 | hormone transport | 7.2289 | 4 | yes |
| GO:0046879 | hormone secretion | 7.2289 | 5 | yes |
| GO:0006812 | cation transport | 6.0241 | 5 | yes |
| GO:0001821 | histamine secretion | 3.6145 | 5 | yes |
| GO:0002441 | histamine secretion involved in inflammatory response | 3.6145 | 6 | yes |
| GO:0051608 | histamine transport | 3.6145 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in SNP23_HUMAN |
|---|---|---|---|---|
| DOID:1826 | epilepsy | 2.4096 | 5 | no |
| DOID:331 | central nervous system disease | 2.4096 | 3 | no |
| DOID:936 | brain disease | 2.4096 | 4 | no |
| DOID:0111962 | combined immunodeficiency | 2.4096 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 2.4096 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SNTG1_HUMAN | [view interactions] | Low throughput | no | no |
| STXB5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX11_HUMAN | [view interactions] | Low throughput | no | yes |
| STX1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX1B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
| SCAM5_HUMAN | [view interactions] | Low throughput | no | yes |
| STX17_HUMAN | [view interactions] | Low throughput | no | yes |
| CFTR_HUMAN | [view interactions] | Low throughput | no | no |
| ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SNAPN_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP7_HUMAN | [view interactions] | Low throughput | no | yes |
| VAMP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| STX4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VAMP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VAMP8_HUMAN | [view interactions] | Low throughput | no | no |
| TLK1_HUMAN | [view interactions] | Low throughput | no | yes |
| SEGN_HUMAN | [view interactions] | Low throughput | no | no |
| STXB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STX2_HUMAN | [view interactions] | Low throughput | no | no |
| KINH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SCAM1_HUMAN | [view interactions] | Low throughput | no | no |
| SCAM2_HUMAN | [view interactions] | Low throughput | no | no |
| STX6_HUMAN | [view interactions] | Low throughput | no | yes |
| IKKA_HUMAN | [view interactions] | Low throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| PTAR1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF2_HUMAN | [view interactions] | High throughput | no | yes |
| SAP_HUMAN | [view interactions] | High throughput | no | yes |
| C10_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| FAM3C_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ROAA_HUMAN | [view interactions] | High throughput | no | yes |
| MIA40_HUMAN | [view interactions] | High throughput | no | yes |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| DNJ5B_HUMAN | [view interactions] | High throughput | no | no |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS12B_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3B_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| WASH2_HUMAN | [view interactions] | High throughput | no | no |
| STB5L_HUMAN | [view interactions] | High throughput | no | no |
| GBG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P20L1_HUMAN | [view interactions] | High throughput | no | yes |
| TBC30_HUMAN | [view interactions] | High throughput | no | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UT2_HUMAN | [view interactions] | High throughput | no | no |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| CEBPD_HUMAN | [view interactions] | High throughput | no | no |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| ZDH17_HUMAN | [view interactions] | High throughput | no | yes |
| SNAB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX18_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP97_HUMAN | [view interactions] | High throughput | no | yes |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX19_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| STXB6_HUMAN | [view interactions] | High throughput | no | yes |
| CHM2A_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP4_HUMAN | [view interactions] | High throughput | no | yes |
| CXB7_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| CLUA1_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| CERS2_HUMAN | [view interactions] | High throughput | no | no |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| NEMO_HUMAN | [view interactions] | Computational | no | yes |
| SC22B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| HLAF_HUMAN | [view interactions] | Computational | no | no |
| HLAC_HUMAN | [view interactions] | Computational | no | no |
| RAB13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GOSR2_HUMAN | [view interactions] | Computational | no | yes |
| EXOC4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CPLX2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HLAA_HUMAN | [view interactions] | Computational | no | no |
| VTI1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| STX16_HUMAN | [view interactions] | Computational | no | yes |
| SNX4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| STXB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ASPC1_HUMAN | [view interactions] | Computational | no | yes |
| HLAB_HUMAN | [view interactions] | Computational | no | yes |
| VTI1A_HUMAN | [view interactions] | Computational | no | yes |
| STXB2_HUMAN | [view interactions] | Computational | no | no |
| GLUT4_HUMAN | [view interactions] | Computational | no | no |
| HLAE_HUMAN | [view interactions] | Computational | no | no |
| ANXA2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CPLX1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| STX8_HUMAN | [view interactions] | Computational | no | yes |
| SNP25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VAMP1_HUMAN | [view interactions] | Computational | no | no |
| EXOC6_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EXOC5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EXOC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| YKT6_HUMAN | [view interactions] | Computational | no | yes |
| EXOC7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EXOC8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HLAG_HUMAN | [view interactions] | Computational | no | no |
| SYT7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| EXOC2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| VAPA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |