Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

HGS_HUMAN

Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation. [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI001341 LIG_PTAP_UEV_1 LIG 347 352 -

Molecular function

Term Name % Distance from the top of the tree Annotated in HGS_HUMAN
GO:0017076 purine nucleotide binding 26.0563 4 no
GO:0032555 purine ribonucleotide binding 25.3521 4 no
GO:0035639 purine ribonucleoside triphosphate binding 25.3521 4 no
GO:0030554 adenyl nucleotide binding 21.1268 5 no
GO:0005524 ATP binding 20.4225 5 no
GO:0032559 adenyl ribonucleotide binding 20.4225 5 no
GO:0046872 metal ion binding 19.0141 4 yes
GO:0044389 ubiquitin-like protein ligase binding 13.3803 4 yes
GO:0035091 phosphatidylinositol binding 8.4507 4 yes
GO:0043130 ubiquitin binding 5.6338 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in HGS_HUMAN
GO:0048522 positive regulation of cellular process 57.7465 4 yes
GO:0060255 regulation of macromolecule metabolic process 53.5211 4 yes
GO:0080090 regulation of primary metabolic process 52.1127 4 yes
GO:0048523 negative regulation of cellular process 51.4085 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 51.4085 4 yes
GO:0031323 regulation of cellular metabolic process 48.5915 4 yes
GO:0010646 regulation of cell communication 47.8873 4 yes
GO:0051128 regulation of cellular component organization 47.1831 4 no
GO:0008104 protein localization 45.0704 4 yes
GO:0006996 organelle organization 43.6620 4 yes
GO:0009893 positive regulation of metabolic process 42.9577 4 yes
GO:0009966 regulation of signal transduction 41.5493 4 yes
GO:0051246 regulation of protein metabolic process 40.8451 5 yes
GO:0016192 vesicle-mediated transport 40.1408 4 yes
GO:0051049 regulation of transport 40.1408 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 38.0282 5 yes
GO:0022607 cellular component assembly 38.0282 4 yes
GO:0071702 organic substance transport 38.0282 4 yes
GO:0071705 nitrogen compound transport 37.3239 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 34.5070 5 no
GO:0010468 regulation of gene expression 33.8028 5 yes
GO:0015031 protein transport 33.8028 4 yes
GO:0010647 positive regulation of cell communication 31.6901 5 no
GO:0023056 positive regulation of signaling 31.6901 4 no
GO:0009892 negative regulation of metabolic process 30.9859 4 no
GO:0031325 positive regulation of cellular metabolic process 30.9859 5 no
GO:0044087 regulation of cellular component biogenesis 29.5775 4 yes
GO:0031399 regulation of protein modification process 28.8732 6 yes
GO:1902531 regulation of intracellular signal transduction 28.8732 5 no
GO:0009889 regulation of biosynthetic process 28.1690 4 no
GO:0048584 positive regulation of response to stimulus 28.1690 4 no
GO:0051247 positive regulation of protein metabolic process 28.1690 6 no
GO:0051172 negative regulation of nitrogen compound metabolic process 26.7606 5 no
GO:0031326 regulation of cellular biosynthetic process 26.7606 5 no
GO:0009967 positive regulation of signal transduction 26.7606 5 no
GO:0051050 positive regulation of transport 26.0563 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 26.0563 5 no
GO:0010605 negative regulation of macromolecule metabolic process 26.0563 5 no
GO:0051130 positive regulation of cellular component organization 26.0563 5 no
GO:0009894 regulation of catabolic process 25.3521 4 yes
GO:0036211 protein modification process 24.6479 4 no
GO:0043412 macromolecule modification 24.6479 4 no
GO:0051240 positive regulation of multicellular organismal process 23.9437 4 no
GO:0010941 regulation of cell death 23.9437 4 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 23.9437 5 no
GO:0033043 regulation of organelle organization 23.2394 5 no
GO:0051252 regulation of RNA metabolic process 23.2394 5 no
GO:0010648 negative regulation of cell communication 22.5352 5 yes
GO:0019220 regulation of phosphate metabolic process 22.5352 6 yes
GO:0023057 negative regulation of signaling 22.5352 4 yes
GO:0048585 negative regulation of response to stimulus 22.5352 4 yes
GO:0051174 regulation of phosphorus metabolic process 22.5352 5 yes
GO:0060341 regulation of cellular localization 22.5352 4 no
GO:0045595 regulation of cell differentiation 22.5352 4 no
GO:0031324 negative regulation of cellular metabolic process 22.5352 5 no
GO:0060627 regulation of vesicle-mediated transport 21.8310 4 yes
GO:0031344 regulation of cell projection organization 21.8310 5 no
GO:0042325 regulation of phosphorylation 21.1268 7 yes
GO:2000026 regulation of multicellular organismal development 21.1268 4 yes
GO:0032880 regulation of protein localization 21.1268 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.1268 6 no
GO:0030030 cell projection organization 21.1268 4 no
GO:0071310 cellular response to organic substance 21.1268 4 no
GO:0009968 negative regulation of signal transduction 20.4225 5 yes
GO:0043933 protein-containing complex organization 20.4225 4 no
GO:1903506 regulation of nucleic acid-templated transcription 20.4225 7 no
GO:2001141 regulation of RNA biosynthetic process 20.4225 6 no
GO:0051094 positive regulation of developmental process 20.4225 4 no
GO:0006886 intracellular protein transport 19.7183 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 19.0141 4 yes
GO:0042127 regulation of cell population proliferation 18.3099 4 yes
GO:0001932 regulation of protein phosphorylation 18.3099 7 yes
GO:0010628 positive regulation of gene expression 16.9014 6 yes
GO:0016050 vesicle organization 16.9014 5 yes
GO:0051241 negative regulation of multicellular organismal process 16.9014 4 yes
GO:0051338 regulation of transferase activity 16.9014 4 yes
GO:0072657 protein localization to membrane 16.9014 4 yes
GO:0016197 endosomal transport 16.1972 4 yes
GO:0044089 positive regulation of cellular component biogenesis 16.1972 5 yes
GO:0051046 regulation of secretion 16.1972 5 yes
GO:0042176 regulation of protein catabolic process 15.4930 5 yes
GO:1903530 regulation of secretion by cell 15.4930 4 yes
GO:0043549 regulation of kinase activity 14.7887 5 yes
GO:0051093 negative regulation of developmental process 14.0845 4 yes
GO:0061024 membrane organization 14.0845 4 yes
GO:0070925 organelle assembly 14.0845 5 yes
GO:0045859 regulation of protein kinase activity 11.9718 6 yes
GO:0007034 vacuolar transport 11.9718 4 yes
GO:0007041 lysosomal transport 11.2676 5 yes
GO:0033365 protein localization to organelle 11.2676 5 yes
GO:0008285 negative regulation of cell population proliferation 9.8592 5 yes
GO:0051047 positive regulation of secretion 9.8592 5 yes
GO:1903532 positive regulation of secretion by cell 9.1549 5 yes
GO:0007032 endosome organization 9.1549 6 yes
GO:0017157 regulation of exocytosis 8.4507 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 8.4507 7 yes
GO:0006605 protein targeting 8.4507 5 yes
GO:0072594 establishment of protein localization to organelle 7.0423 4 yes
GO:0016236 macroautophagy 6.3380 4 yes
GO:0036257 multivesicular body organization 6.3380 7 yes
GO:0036258 multivesicular body assembly 6.3380 6 yes
GO:0043405 regulation of MAP kinase activity 6.3380 8 yes
GO:0045765 regulation of angiogenesis 6.3380 5 yes
GO:1901342 regulation of vasculature development 6.3380 5 yes
GO:0072665 protein localization to vacuole 5.6338 6 yes
GO:0072666 establishment of protein localization to vacuole 5.6338 5 yes
GO:0045921 positive regulation of exocytosis 4.9296 6 yes
GO:0061462 protein localization to lysosome 4.9296 7 yes
GO:0006622 protein targeting to lysosome 4.9296 6 yes
GO:0006623 protein targeting to vacuole 4.9296 5 yes
GO:0016525 negative regulation of angiogenesis 4.2254 6 yes
GO:0090287 regulation of cellular response to growth factor stimulus 4.2254 4 yes
GO:1901343 negative regulation of vasculature development 4.2254 5 yes
GO:2000181 negative regulation of blood vessel morphogenesis 4.2254 5 yes
GO:1903541 regulation of exosomal secretion 3.5211 6 yes
GO:1903543 positive regulation of exosomal secretion 3.5211 6 yes
GO:0090288 negative regulation of cellular response to growth factor stimulus 2.8169 5 yes
GO:0010324 membrane invagination 2.1127 5 yes
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 2.1127 5 yes
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2.1127 5 yes
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 2.1127 6 yes
GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2.1127 6 yes
GO:1904892 regulation of receptor signaling pathway via STAT 2.1127 5 yes
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1.4085 6 yes
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1.4085 7 yes
GO:1904893 negative regulation of receptor signaling pathway via STAT 1.4085 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in HGS_HUMAN
DOID:331 central nervous system disease 3.5211 3 no
DOID:1289 neurodegenerative disease 2.1127 4 no
DOID:936 brain disease 1.4085 4 no
DOID:0050686 organ system cancer 1.4085 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SNX5_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN23_HUMAN [view entry] [view interactions] Low throughput yes yes
IL2RA_HUMAN [view interactions] Low throughput no no
DTX3L_HUMAN [view interactions] Low throughput no yes
LRIG1_HUMAN [view interactions] Low throughput no yes
MET_HUMAN [view interactions] Low throughput no yes
LAP4B_HUMAN [view interactions] Low throughput no yes
NOTC1_HUMAN [view interactions] Low throughput no yes
FLOT1_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
M3K7_HUMAN [view interactions] Low throughput no yes
UBE4B_HUMAN [view interactions] Low throughput no yes
NEDD8_HUMAN [view interactions] Low throughput no yes
FLOT2_HUMAN [view entry] [view interactions] Low throughput yes yes
KSYK_HUMAN [view interactions] Low throughput no no
CSK21_HUMAN [view entry] [view interactions] Low throughput yes yes
CXA1_HUMAN [view entry] [view interactions] Low throughput yes yes
ROCK1_HUMAN [view entry] [view interactions] Low throughput yes yes
OPRM_HUMAN [view entry] [view interactions] Low throughput yes no
SYPH_HUMAN [view entry] [view interactions] Low throughput yes yes
UBQL1_HUMAN [view interactions] Low throughput no yes
RAB4A_HUMAN [view entry] [view interactions] Low throughput yes no
RAB7A_HUMAN [view entry] [view interactions] Low throughput yes yes
RB11A_HUMAN [view entry] [view interactions] Low throughput yes yes
ERBB3_HUMAN [view interactions] Low throughput no yes
FGFR2_HUMAN [view interactions] Low throughput no yes
EPS15_HUMAN [view entry] [view interactions] Low throughput yes yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
SNP25_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
TS101_HUMAN [view entry] [view interactions] Low throughput yes yes
LYST_HUMAN [view interactions] Low throughput no no
TOM1_HUMAN [view interactions] Low throughput no yes
ARMC8_HUMAN [view interactions] Low throughput no yes
TM1L1_HUMAN [view interactions] Low throughput no yes
SMAD5_HUMAN [view interactions] Low throughput no no
GGA2_HUMAN [view interactions] Low throughput no yes
PELP1_HUMAN [view interactions] Low throughput no yes
GGA1_HUMAN [view interactions] Low throughput no yes
GGA3_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTN4_HUMAN [view entry] [view interactions] Low throughput yes yes
SNP23_HUMAN [view entry] [view interactions] Low throughput yes no
CEP55_HUMAN [view interactions] Low throughput no yes
PMEPA_HUMAN [view interactions] Low throughput no no
HAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
MERL_HUMAN [view interactions] Low throughput no yes
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
ARRB2_HUMAN [view entry] [view interactions] Low throughput yes no
ARRD3_HUMAN [view interactions] Low throughput no no
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PCDA4_HUMAN [view interactions] Low throughput no yes
GP143_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
STAM2_HUMAN [view interactions] Low throughput no yes
RAB14_HUMAN [view entry] [view interactions] Low throughput yes yes
EGFR_HUMAN [view interactions] Low throughput no no
NTRK2_HUMAN [view entry] [view interactions] Low throughput yes yes
HGS_HUMAN [view entry] [view interactions] Low throughput yes yes
STAM1_HUMAN [view interactions] Low throughput no yes
VP37C_HUMAN [view interactions] Low throughput no yes
WASH1_HUMAN [view interactions] Low throughput no yes
SCAM3_HUMAN [view interactions] Low throughput no no
IL2RB_HUMAN [view interactions] Low throughput no no
IL6RB_HUMAN [view interactions] Low throughput no no
VPS4A_HUMAN [view entry] [view interactions] Low throughput yes yes
ITCH_HUMAN [view interactions] Low throughput no yes
OCLN_HUMAN [view interactions] Low throughput no no
ABCA1_HUMAN [view interactions] Low throughput no yes
JAG1_HUMAN [view interactions] Low throughput no no
SH3K1_HUMAN [view entry] [view interactions] Low throughput yes yes
IL4RA_HUMAN [view interactions] Low throughput no no
SCNNA_HUMAN [view interactions] Low throughput no yes
SCNNB_HUMAN [view interactions] Low throughput no yes
NED4L_HUMAN [view interactions] Low throughput no yes
PDES1_HUMAN [view interactions] Low throughput no no
TRAK2_HUMAN [view interactions] Low throughput no yes
TFR1_HUMAN [view interactions] Low throughput no yes
INSR_HUMAN [view interactions] Low throughput no yes
VEGFA_HUMAN [view entry] [view interactions] Low throughput yes yes
TLR4_HUMAN [view interactions] Low throughput no yes
CD4_HUMAN [view interactions] Low throughput no no
SMAD1_HUMAN [view interactions] Low throughput no yes
SMAD3_HUMAN [view interactions] Low throughput no yes
SMAD2_HUMAN [view interactions] Low throughput no yes
SMAD4_HUMAN [view interactions] Low throughput no yes
BST2_HUMAN [view interactions] Low throughput no yes
TRAK1_HUMAN [view interactions] Low throughput no yes
SNX1_HUMAN [view entry] [view interactions] Low throughput yes yes
VPS35_HUMAN [view entry] [view interactions] Low throughput yes yes
VAMP2_HUMAN [view entry] [view interactions] Low throughput yes no
STX12_HUMAN [view entry] [view interactions] Low throughput yes yes
SPY2_HUMAN [view interactions] Low throughput no yes
TRIM3_HUMAN [view entry] [view interactions] Low throughput yes no
MYO5A_HUMAN [view entry] [view interactions] Low throughput yes yes
CTRO_HUMAN [view entry] [view interactions] Low throughput yes yes
RNF11_HUMAN [view interactions] Low throughput no yes
ADRB2_HUMAN [view entry] [view interactions] Low throughput yes no
V2R_HUMAN [view interactions] Low throughput no no
STX1A_HUMAN [view entry] [view interactions] Low throughput yes yes
KRT37_HUMAN [view interactions] High throughput no no
EX3L1_HUMAN [view interactions] High throughput no yes
K2C75_HUMAN [view interactions] High throughput no no
K1C26_HUMAN [view interactions] High throughput no no
KRT35_HUMAN [view interactions] High throughput no no
PO6F2_HUMAN [view interactions] High throughput no no
K1C27_HUMAN [view interactions] High throughput no no
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
MOONR_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
FSD2_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
K1C39_HUMAN [view interactions] High throughput no no
UBQL2_HUMAN [view interactions] High throughput no yes
TNR3_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
VP33B_HUMAN [view interactions] High throughput no yes
TAD2A_HUMAN [view interactions] High throughput no no
PAX5_HUMAN [view interactions] High throughput no no
HPBP1_HUMAN [view interactions] High throughput no yes
VINEX_HUMAN [view interactions] High throughput no no
B2CL1_HUMAN [view interactions] High throughput no yes
K2C3_HUMAN [view interactions] High throughput no no
FIGN_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
NUP62_HUMAN [view interactions] High throughput no yes
PKNX2_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
TRI23_HUMAN [view interactions] High throughput no yes
KI2L4_HUMAN [view interactions] High throughput no no
PAX6_HUMAN [view interactions] High throughput no no
KCNE3_HUMAN [view interactions] High throughput no yes
TEKT5_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
TBX19_HUMAN [view interactions] High throughput no no
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
MKRN3_HUMAN [view interactions] High throughput no yes
CEL2A_HUMAN [view interactions] High throughput no no
SRTD3_HUMAN [view interactions] High throughput no no
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
TFG_HUMAN [view interactions] High throughput no yes
EDAR_HUMAN [view interactions] High throughput no yes
TRI27_HUMAN [view interactions] High throughput no yes
NRSN1_HUMAN [view interactions] High throughput no yes
MED25_HUMAN [view interactions] High throughput no yes
AQP9_HUMAN [view interactions] High throughput no no
DYDC1_HUMAN [view interactions] High throughput no no
TGM1_HUMAN [view interactions] High throughput no no
DTX2_HUMAN [view interactions] High throughput no yes
R9BP_HUMAN [view interactions] High throughput no no
BICRL_HUMAN [view interactions] High throughput no yes
HSP72_HUMAN [view entry] [view interactions] High throughput yes no
BFSP2_HUMAN [view interactions] High throughput no no
CTLA4_HUMAN [view interactions] High throughput no no
OBF1_HUMAN [view interactions] High throughput no no
TGM7_HUMAN [view interactions] High throughput no no
K1C16_HUMAN [view interactions] High throughput no no
RM42_HUMAN [view interactions] High throughput no yes
K1C18_HUMAN [view interactions] High throughput no no
RDH14_HUMAN [view interactions] High throughput no yes
TRIMM_HUMAN [view interactions] High throughput no no
LIRA5_HUMAN [view interactions] High throughput no no
K1C19_HUMAN [view interactions] High throughput no no
TUSC2_HUMAN [view interactions] High throughput no no
T11L2_HUMAN [view interactions] High throughput no yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
SRGEF_HUMAN [view interactions] High throughput no yes
NTNG1_HUMAN [view interactions] High throughput no no
GOG7B_HUMAN [view entry] [view interactions] High throughput yes yes
TR19L_HUMAN [view interactions] High throughput no no
UBQLN_HUMAN [view interactions] High throughput no no
FBX32_HUMAN [view interactions] High throughput no no
K1C24_HUMAN [view entry] [view interactions] High throughput yes no
RHOJ_HUMAN [view interactions] High throughput no yes
NADE_HUMAN [view interactions] High throughput no yes
RHOU_HUMAN [view interactions] High throughput no no
RSPO4_HUMAN [view interactions] High throughput no no
PSA5_HUMAN [view interactions] High throughput no yes
FBN1_HUMAN [view interactions] High throughput no no
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
STMN3_HUMAN [view interactions] High throughput no yes
HMGN5_HUMAN [view interactions] High throughput no no
LMO4_HUMAN [view interactions] High throughput no yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
RBTN1_HUMAN [view interactions] High throughput no no
IST1_HUMAN [view interactions] High throughput no yes
SMRP1_HUMAN [view interactions] High throughput no yes
MB12A_HUMAN [view interactions] High throughput no yes
AKP8L_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
MS18B_HUMAN [view interactions] High throughput no no
RIT1_HUMAN [view interactions] High throughput no yes
ODAM_HUMAN [view interactions] High throughput no no
MET27_HUMAN [view interactions] High throughput no yes
EIF3F_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
KLF4_HUMAN [view interactions] High throughput no no
APLP2_HUMAN [view interactions] High throughput no yes
SPT12_HUMAN [view interactions] High throughput no no
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
F185A_HUMAN [view interactions] High throughput no no
AR6P1_HUMAN [view interactions] High throughput no yes
BBC3B_HUMAN [view interactions] High throughput no yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
PLCD1_HUMAN [view entry] [view interactions] High throughput yes yes
TIDC1_HUMAN [view interactions] High throughput no yes
CT173_HUMAN [view interactions] High throughput no no
BRNP3_HUMAN [view interactions] High throughput no yes
FTCD_HUMAN [view interactions] High throughput no no
VMP1_HUMAN [view interactions] High throughput no yes
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
SUN2_HUMAN [view interactions] High throughput no yes
MED30_HUMAN [view interactions] High throughput no no
SAHH2_HUMAN [view entry] [view interactions] High throughput yes yes
ARMC7_HUMAN [view interactions] High throughput no yes
CSKP_HUMAN [view entry] [view interactions] High throughput yes yes
KR195_HUMAN [view interactions] High throughput no no
ZO2_HUMAN [view entry] [view interactions] High throughput yes no
ADA2C_HUMAN [view entry] [view interactions] High throughput yes no
M3K10_HUMAN [view interactions] High throughput no yes
GATC_HUMAN [view interactions] High throughput no no
STXB1_HUMAN [view entry] [view interactions] High throughput yes yes
RNF4_HUMAN [view interactions] High throughput no yes
SCRN1_HUMAN [view entry] [view interactions] High throughput yes yes
SDHL_HUMAN [view interactions] High throughput no yes
DPYL1_HUMAN [view entry] [view interactions] High throughput yes yes
HAUS1_HUMAN [view interactions] High throughput no yes
DCTN2_HUMAN [view entry] [view interactions] High throughput yes yes
K1C14_HUMAN [view interactions] High throughput no no
GFAP_HUMAN [view entry] [view interactions] High throughput yes no
KRT82_HUMAN [view interactions] High throughput no no
MARK4_HUMAN [view interactions] High throughput no yes
FX4L1_HUMAN [view interactions] High throughput no no
PP16A_HUMAN [view interactions] High throughput no no
CEAM6_HUMAN [view interactions] High throughput no no
RHBT3_HUMAN [view interactions] High throughput no no
IPO4_HUMAN [view interactions] High throughput no no
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
PA2GX_HUMAN [view interactions] High throughput no no
ERR3_HUMAN [view interactions] High throughput no yes
SECR_HUMAN [view interactions] High throughput no no
ILKAP_HUMAN [view interactions] High throughput no yes
KRT86_HUMAN [view interactions] High throughput no no
PP1R7_HUMAN [view entry] [view interactions] High throughput yes yes
ANR55_HUMAN [view interactions] High throughput no yes
RSU1_HUMAN [view interactions] High throughput no no
PSB11_HUMAN [view interactions] High throughput no no
ACLY_HUMAN [view entry] [view interactions] High throughput yes yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
CBS_HUMAN [view interactions] High throughput no yes
PKHB2_HUMAN [view interactions] High throughput no yes
DECR_HUMAN [view entry] [view interactions] High throughput yes yes
BL1S1_HUMAN [view interactions] High throughput no yes
METK2_HUMAN [view interactions] High throughput no no
CCND3_HUMAN [view interactions] High throughput no no
C1TM_HUMAN [view entry] [view interactions] High throughput yes yes
ST32C_HUMAN [view entry] [view interactions] High throughput yes yes
OSBL5_HUMAN [view interactions] High throughput no yes
LRC61_HUMAN [view interactions] High throughput no yes
PLD3_HUMAN [view entry] [view interactions] High throughput yes yes
GUC1C_HUMAN [view interactions] High throughput no no
PFKAM_HUMAN [view entry] [view interactions] High throughput yes yes
FND11_HUMAN [view interactions] High throughput no no
HNRDL_HUMAN [view interactions] High throughput no yes
ANKMT_HUMAN [view interactions] High throughput no yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
P2R3B_HUMAN [view interactions] High throughput no no
SF3B3_HUMAN [view interactions] High throughput no yes
K0825_HUMAN [view interactions] High throughput no yes
PTCD3_HUMAN [view interactions] High throughput no yes
JMJD7_HUMAN [view interactions] High throughput no yes
ZN302_HUMAN [view interactions] High throughput no no
T10B_HUMAN [view interactions] High throughput no yes
MEST_HUMAN [view interactions] High throughput no no
SPC25_HUMAN [view interactions] High throughput no no
TMCC2_HUMAN [view interactions] High throughput no yes
PSB4_HUMAN [view interactions] High throughput no yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
DSN1_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
CK001_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
IFN16_HUMAN [view interactions] High throughput no no
PLAT1_HUMAN [view interactions] High throughput no no
KRA71_HUMAN [view interactions] High throughput no no
MED21_HUMAN [view interactions] High throughput no yes
UBAP2_HUMAN [view interactions] High throughput no yes
F166A_HUMAN [view interactions] High throughput no no
RASF4_HUMAN [view interactions] High throughput no yes
CC036_HUMAN [view interactions] High throughput no no
EGFL7_HUMAN [view interactions] High throughput no yes
MOG1_HUMAN [view interactions] High throughput no yes
SUMO5_HUMAN [view interactions] High throughput no no
GKAP1_HUMAN [view interactions] High throughput no no
HGH1_HUMAN [view interactions] High throughput no no
EHMT2_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A3_HUMAN [view interactions] High throughput no yes
EXOC8_HUMAN [view entry] [view interactions] High throughput yes yes
SLK_HUMAN [view entry] [view interactions] High throughput yes yes
CCD33_HUMAN [view interactions] High throughput no no
TTC4_HUMAN [view interactions] High throughput no yes
BEGIN_HUMAN [view entry] [view interactions] High throughput yes no
REPI1_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
SNX2_HUMAN [view entry] [view interactions] High throughput yes no
APC_HUMAN [view entry] [view interactions] High throughput yes no
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
SC23A_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX12_HUMAN [view entry] [view interactions] High throughput yes yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
SYJ2B_HUMAN [view entry] [view interactions] High throughput yes no
TOM22_HUMAN [view interactions] High throughput no yes
DNJC5_HUMAN [view interactions] High throughput no yes
LAT1_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] High throughput no yes
PTPR2_HUMAN [view interactions] High throughput no yes
UB2V1_HUMAN [view entry] [view interactions] High throughput yes no
PTH2_HUMAN [view interactions] High throughput no yes
UBA1_HUMAN [view entry] [view interactions] High throughput yes yes
BICD1_HUMAN [view interactions] High throughput no yes
UBE2N_HUMAN [view entry] [view interactions] High throughput yes yes
RHDF2_HUMAN [view interactions] High throughput no yes
TMM17_HUMAN [view interactions] High throughput no yes
MIB1_HUMAN [view entry] [view interactions] High throughput yes yes
BET1_HUMAN [view interactions] High throughput no no
SMAP2_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
DCP1A_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view interactions] High throughput no yes
RN183_HUMAN [view interactions] High throughput no no
PLRKT_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view interactions] High throughput no yes
ATG12_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
B3GA1_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
CK052_HUMAN [view interactions] High throughput no no
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
CAV1_HUMAN [view interactions] High throughput no no
CSF1R_HUMAN [view interactions] High throughput no yes
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
EPHA2_HUMAN [view interactions] High throughput no no
DIRA3_HUMAN [view interactions] High throughput no yes
EPHA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
EPHA4_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
EPHA5_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
EPHA7_HUMAN [view entry] [view interactions] High throughput yes no
MET7A_HUMAN [view interactions] High throughput no no
EPHA8_HUMAN [view interactions] High throughput no no
PERI_HUMAN [view entry] [view interactions] High throughput yes no
EPHB2_HUMAN [view entry] [view interactions] High throughput yes yes
RAB9A_HUMAN [view interactions] High throughput no yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
STX6_HUMAN [view interactions] High throughput no yes
FGFR3_HUMAN [view interactions] High throughput no yes
SYNE3_HUMAN [view interactions] High throughput no no
FGFR4_HUMAN [view interactions] High throughput no no
VINC_HUMAN [view entry] [view interactions] High throughput yes no
PTN11_HUMAN [view entry] [view interactions] High throughput yes yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
NTRK1_HUMAN [view interactions] High throughput no yes
ZFPL1_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
ZYX_HUMAN [view interactions] High throughput no no
PGFRA_HUMAN [view interactions] High throughput no no
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRB_HUMAN [view interactions] High throughput no yes
TMPS2_HUMAN [view interactions] High throughput no no
RET_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
RYK_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
STYK1_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
CACO2_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3B_HUMAN [view interactions] High throughput no yes
RNF43_HUMAN [view interactions] High throughput no yes
ATX1L_HUMAN [view interactions] High throughput no no
UBQL4_HUMAN [view interactions] High throughput no yes
GFI1B_HUMAN [view interactions] High throughput no no
DGCR6_HUMAN [view interactions] High throughput no no
CE57L_HUMAN [view interactions] High throughput no yes
MKNK1_HUMAN [view interactions] High throughput no yes
FANCG_HUMAN [view interactions] High throughput no yes
TLE5_HUMAN [view interactions] High throughput no no
NFL_HUMAN [view entry] [view interactions] High throughput yes yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
FCSD2_HUMAN [view interactions] High throughput no no
F168A_HUMAN [view interactions] High throughput no yes
CREST_HUMAN [view interactions] High throughput no yes
CC136_HUMAN [view interactions] High throughput no yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
CEP63_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
TRI69_HUMAN [view interactions] High throughput no no
DEUP1_HUMAN [view interactions] High throughput no no
PNMA1_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
HOIL1_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
TASO2_HUMAN [view interactions] High throughput no yes
RINT1_HUMAN [view interactions] High throughput no yes
LASP1_HUMAN [view entry] [view interactions] High throughput yes yes
CEP68_HUMAN [view interactions] High throughput no yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
RFC2_HUMAN [view interactions] High throughput no yes
EPHA6_HUMAN [view interactions] High throughput no no
EYA2_HUMAN [view interactions] High throughput no yes
NFYC_HUMAN [view interactions] High throughput no no
YPEL3_HUMAN [view interactions] High throughput no yes
TX101_HUMAN [view interactions] High throughput no no
IFT74_HUMAN [view interactions] High throughput no yes
SNF5_HUMAN [view interactions] High throughput no yes
HSF4_HUMAN [view interactions] High throughput no no
MEIS3_HUMAN [view interactions] High throughput no no
NDC80_HUMAN [view interactions] High throughput no no
ATN1_HUMAN [view interactions] High throughput no yes
MI4GD_HUMAN [view interactions] High throughput no yes
ZN430_HUMAN [view interactions] High throughput no no
SUMO1_HUMAN [view interactions] High throughput no yes
KRT36_HUMAN [view interactions] High throughput no no
K1C15_HUMAN [view interactions] High throughput no no
NTM2F_HUMAN [view interactions] High throughput no no
LDOC1_HUMAN [view interactions] High throughput no no
RPR1A_HUMAN [view interactions] High throughput no yes
KRT38_HUMAN [view interactions] High throughput no no
DAAM2_HUMAN [view entry] [view interactions] High throughput yes yes
K1C40_HUMAN [view interactions] High throughput no no
MED22_HUMAN [view interactions] High throughput no no
K1H1_HUMAN [view interactions] High throughput no no
UBX11_HUMAN [view interactions] High throughput no yes
DAZP2_HUMAN [view interactions] High throughput no no
RUNX1_HUMAN [view interactions] High throughput no yes
ING5_HUMAN [view interactions] High throughput no yes
PPR32_HUMAN [view interactions] High throughput no no
P4HA3_HUMAN [view interactions] High throughput no no
ACO11_HUMAN [view interactions] High throughput no yes
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
ICA1L_HUMAN [view interactions] High throughput no yes
ODAD1_HUMAN [view interactions] High throughput no no
UBP54_HUMAN [view interactions] High throughput no yes
MAGB4_HUMAN [view interactions] High throughput no no
NB5R2_HUMAN [view interactions] High throughput no no
SPF27_HUMAN [view interactions] High throughput no yes
FOXI1_HUMAN [view interactions] High throughput no no
K2C6A_HUMAN [view entry] [view interactions] High throughput yes no
TRI73_HUMAN [view interactions] High throughput no no
CSTF2_HUMAN [view interactions] High throughput no yes
ARFP2_HUMAN [view interactions] High throughput no no
PRR5_HUMAN [view interactions] High throughput no yes
NUP54_HUMAN [view interactions] High throughput no yes
ZNF34_HUMAN [view interactions] High throughput no no
POGZ_HUMAN [view interactions] High throughput no yes
ZNF44_HUMAN [view interactions] High throughput no yes
CC103_HUMAN [view interactions] High throughput no no
ASB12_HUMAN [view interactions] High throughput no no
MISSL_HUMAN [view interactions] High throughput no yes
CDSN_HUMAN [view interactions] High throughput no no
JKIP2_HUMAN [view entry] [view interactions] High throughput yes no
TRI10_HUMAN [view interactions] High throughput no no
MR1L1_HUMAN [view interactions] High throughput no no
SPIR2_HUMAN [view interactions] High throughput no yes
INT4_HUMAN [view interactions] High throughput no yes
VGLL3_HUMAN [view interactions] High throughput no no
LITAF_HUMAN [view interactions] High throughput no yes
PRR22_HUMAN [view interactions] High throughput no no
CSTFT_HUMAN [view interactions] High throughput no yes
SAPC1_HUMAN [view interactions] High throughput no no
CT2NL_HUMAN [view interactions] High throughput no yes
PEF1_HUMAN [view interactions] High throughput no no
SNX7_HUMAN [view interactions] High throughput no yes
EXOC7_HUMAN [view entry] [view interactions] High throughput yes yes
NPAS2_HUMAN [view interactions] High throughput no yes
PITX1_HUMAN [view interactions] High throughput no yes
HSFY1_HUMAN [view interactions] High throughput no no
KR261_HUMAN [view interactions] High throughput no no
EXOC5_HUMAN [view entry] [view interactions] High throughput yes yes
VPS52_HUMAN [view entry] [view interactions] High throughput yes no
TEKT1_HUMAN [view interactions] High throughput no no
NMI_HUMAN [view interactions] High throughput no yes
RFX6_HUMAN [view interactions] High throughput no no
CRX_HUMAN [view interactions] High throughput no no
TRAF4_HUMAN [view interactions] High throughput no yes
VP37B_HUMAN [view interactions] High throughput no yes
K1C13_HUMAN [view interactions] High throughput no no
COG8_HUMAN [view interactions] High throughput no no
MED7_HUMAN [view interactions] High throughput no no
KT33B_HUMAN [view interactions] High throughput no no
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
CDR2_HUMAN [view interactions] High throughput no yes
USBP1_HUMAN [view interactions] High throughput no no
STX11_HUMAN [view interactions] High throughput no yes
CA094_HUMAN [view interactions] High throughput no no
MAGD1_HUMAN [view interactions] High throughput no no
TRI17_HUMAN [view interactions] High throughput no yes
ACTN3_HUMAN [view entry] [view interactions] High throughput yes no
GG6L9_HUMAN [view interactions] High throughput no no
TRI54_HUMAN [view interactions] High throughput no no
BORC6_HUMAN [view interactions] High throughput no yes
LURA1_HUMAN [view interactions] High throughput no yes
EFHC2_HUMAN [view interactions] High throughput no no
TRAF1_HUMAN [view interactions] High throughput no no
KRT34_HUMAN [view interactions] High throughput no no
K1C25_HUMAN [view interactions] High throughput no no
K22O_HUMAN [view interactions] High throughput no no
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
UBB_HUMAN [view entry] [view interactions] Computational yes yes
RS27A_HUMAN [view entry] [view interactions] Computational yes yes
RL40_HUMAN [view entry] [view interactions] Computational yes yes
VP37A_HUMAN [view interactions] Computational no yes
VP37D_HUMAN [view interactions] Computational no no
CHM4A_HUMAN [view interactions] Computational no no
UBP8_HUMAN [view entry] [view interactions] Computational yes no
CHMP7_HUMAN [view interactions] Computational no yes
SRC_HUMAN [view entry] [view interactions] Computational yes no
CHM1A_HUMAN [view entry] [view interactions] Computational yes no
HGF_HUMAN [view interactions] Computational no yes
SNF8_HUMAN [view interactions] Computational no yes
SDF1_HUMAN [view interactions] Computational no no
CHM1B_HUMAN [view interactions] Computational no yes
MB12B_HUMAN [view interactions] Computational no no
CHM2B_HUMAN [view entry] [view interactions] Computational yes yes
CHMP6_HUMAN [view interactions] Computational no yes
AP1G2_HUMAN [view interactions] Computational no yes
CHM4B_HUMAN [view entry] [view interactions] Computational yes yes
CHM2A_HUMAN [view interactions] Computational no yes
VPS25_HUMAN [view interactions] Computational no yes
VPS36_HUMAN [view interactions] Computational no yes
EP15R_HUMAN [view entry] [view interactions] Computational yes yes
PTN3_HUMAN [view interactions] Computational no yes
EGF_HUMAN [view interactions] Computational no no
CADH1_HUMAN [view entry] [view interactions] Computational yes no
VPS28_HUMAN [view entry] [view interactions] Computational yes yes
UBAP1_HUMAN [view interactions] Computational no yes
EPN1_HUMAN [view entry] [view interactions] Computational yes yes
CTNB1_HUMAN [view entry] [view interactions] Computational yes yes
CXCR4_HUMAN [view interactions] Computational no no
VPS4B_HUMAN [view interactions] Computational no yes
HPSE_HUMAN [view interactions] Computational no no