Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SCRN1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SCRN1_HUMAN
GO:0046872 metal ion binding 28.5714 4 no
GO:0019900 kinase binding 28.5714 4 no
GO:0001664 G protein-coupled receptor binding 21.4286 4 no
GO:0043130 ubiquitin binding 21.4286 4 no
GO:0044389 ubiquitin-like protein ligase binding 21.4286 4 no
GO:0035091 phosphatidylinositol binding 21.4286 4 no
GO:0019901 protein kinase binding 21.4286 5 no
GO:0003677 DNA binding 21.4286 4 no
GO:0015631 tubulin binding 21.4286 4 no
GO:0008234 cysteine-type peptidase activity 14.2857 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SCRN1_HUMAN
GO:0048523 negative regulation of cellular process 78.5714 4 no
GO:0009966 regulation of signal transduction 71.4286 4 no
GO:0010646 regulation of cell communication 71.4286 4 no
GO:0048522 positive regulation of cellular process 71.4286 4 no
GO:0051171 regulation of nitrogen compound metabolic process 71.4286 4 no
GO:0060255 regulation of macromolecule metabolic process 71.4286 4 no
GO:0080090 regulation of primary metabolic process 71.4286 4 no
GO:0031323 regulation of cellular metabolic process 64.2857 4 no
GO:0051246 regulation of protein metabolic process 64.2857 5 no
GO:0009893 positive regulation of metabolic process 57.1429 4 no
GO:0031399 regulation of protein modification process 57.1429 6 no
GO:0010941 regulation of cell death 50.0000 4 no
GO:0019220 regulation of phosphate metabolic process 50.0000 6 no
GO:0051174 regulation of phosphorus metabolic process 50.0000 5 no
GO:1902531 regulation of intracellular signal transduction 50.0000 5 no
GO:0006996 organelle organization 50.0000 4 no
GO:0009892 negative regulation of metabolic process 42.8571 4 no
GO:0010605 negative regulation of macromolecule metabolic process 42.8571 5 no
GO:0031324 negative regulation of cellular metabolic process 42.8571 5 no
GO:0043067 regulation of programmed cell death 42.8571 5 no
GO:0051049 regulation of transport 42.8571 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 42.8571 5 no
GO:0042325 regulation of phosphorylation 42.8571 7 no
GO:0010468 regulation of gene expression 42.8571 5 no
GO:0010604 positive regulation of macromolecule metabolic process 42.8571 5 no
GO:0008104 protein localization 42.8571 4 no
GO:0022603 regulation of anatomical structure morphogenesis 42.8571 4 no
GO:0032880 regulation of protein localization 42.8571 5 no
GO:0060341 regulation of cellular localization 42.8571 4 no
GO:0009968 negative regulation of signal transduction 35.7143 5 no
GO:0010648 negative regulation of cell communication 35.7143 5 no
GO:0023057 negative regulation of signaling 35.7143 4 no
GO:0031325 positive regulation of cellular metabolic process 35.7143 5 no
GO:0042981 regulation of apoptotic process 35.7143 6 no
GO:0048585 negative regulation of response to stimulus 35.7143 4 no
GO:0051240 positive regulation of multicellular organismal process 35.7143 4 no
GO:0051241 negative regulation of multicellular organismal process 35.7143 4 no
GO:0051248 negative regulation of protein metabolic process 35.7143 6 no
GO:0060627 regulation of vesicle-mediated transport 35.7143 4 no
GO:0009894 regulation of catabolic process 35.7143 4 no
GO:0043549 regulation of kinase activity 35.7143 5 no
GO:0051338 regulation of transferase activity 35.7143 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 35.7143 5 no
GO:0010038 response to metal ion 35.7143 4 no
GO:0022607 cellular component assembly 35.7143 4 no
GO:0033365 protein localization to organelle 35.7143 5 no
GO:0051094 positive regulation of developmental process 35.7143 4 no
GO:0051128 regulation of cellular component organization 35.7143 4 no
GO:0051129 negative regulation of cellular component organization 35.7143 5 no
GO:0045595 regulation of cell differentiation 35.7143 4 no
GO:0051093 negative regulation of developmental process 35.7143 4 no
GO:0016192 vesicle-mediated transport 28.5714 4 yes
GO:0009967 positive regulation of signal transduction 28.5714 5 no
GO:0010647 positive regulation of cell communication 28.5714 5 no
GO:0023056 positive regulation of signaling 28.5714 4 no
GO:0031400 negative regulation of protein modification process 28.5714 7 no
GO:0043066 negative regulation of apoptotic process 28.5714 7 no
GO:0043069 negative regulation of programmed cell death 28.5714 6 no
GO:0043086 negative regulation of catalytic activity 28.5714 4 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0051050 positive regulation of transport 28.5714 4 no
GO:0060548 negative regulation of cell death 28.5714 5 no
GO:0001932 regulation of protein phosphorylation 28.5714 7 no
GO:0006508 proteolysis 28.5714 4 no
GO:0031329 regulation of cellular catabolic process 28.5714 5 no
GO:0036211 protein modification process 28.5714 4 no
GO:0043412 macromolecule modification 28.5714 4 no
GO:0045859 regulation of protein kinase activity 28.5714 6 no
GO:0006355 regulation of DNA-templated transcription 28.5714 6 no
GO:0009889 regulation of biosynthetic process 28.5714 4 no
GO:0010556 regulation of macromolecule biosynthetic process 28.5714 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.5714 5 no
GO:0031326 regulation of cellular biosynthetic process 28.5714 5 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0051252 regulation of RNA metabolic process 28.5714 5 no
GO:1903506 regulation of nucleic acid-templated transcription 28.5714 7 no
GO:2001141 regulation of RNA biosynthetic process 28.5714 6 no
GO:0030030 cell projection organization 28.5714 4 no
GO:0031175 neuron projection development 28.5714 6 no
GO:0031344 regulation of cell projection organization 28.5714 5 no
GO:0043933 protein-containing complex organization 28.5714 4 no
GO:0051130 positive regulation of cellular component organization 28.5714 5 no
GO:0065003 protein-containing complex assembly 28.5714 5 no
GO:0120036 plasma membrane bounded cell projection organization 28.5714 5 no
GO:1903829 positive regulation of protein localization 28.5714 5 no
GO:0044087 regulation of cellular component biogenesis 28.5714 4 no
GO:0045597 positive regulation of cell differentiation 28.5714 5 no
GO:0060284 regulation of cell development 28.5714 5 no
GO:0070201 regulation of establishment of protein localization 28.5714 6 no
GO:0080134 regulation of response to stress 28.5714 4 no
GO:2000026 regulation of multicellular organismal development 28.5714 4 no
GO:0010563 negative regulation of phosphorus metabolic process 21.4286 6 no
GO:0017157 regulation of exocytosis 21.4286 5 no
GO:0031667 response to nutrient levels 21.4286 4 no
GO:0042127 regulation of cell population proliferation 21.4286 4 no
GO:0043085 positive regulation of catalytic activity 21.4286 4 no
GO:0043408 regulation of MAPK cascade 21.4286 6 no
GO:0044057 regulation of system process 21.4286 4 no
GO:0045936 negative regulation of phosphate metabolic process 21.4286 7 no
GO:0050804 modulation of chemical synaptic transmission 21.4286 5 no
GO:0051046 regulation of secretion 21.4286 5 no
GO:0051047 positive regulation of secretion 21.4286 5 no
GO:0051051 negative regulation of transport 21.4286 4 no
GO:0051336 regulation of hydrolase activity 21.4286 4 no
GO:0099177 regulation of trans-synaptic signaling 21.4286 4 no
GO:1902533 positive regulation of intracellular signal transduction 21.4286 6 no
GO:1903530 regulation of secretion by cell 21.4286 4 no
GO:2000377 regulation of reactive oxygen species metabolic process 21.4286 5 no
GO:2000379 positive regulation of reactive oxygen species metabolic process 21.4286 6 no
GO:2001233 regulation of apoptotic signaling pathway 21.4286 5 no
GO:2001234 negative regulation of apoptotic signaling pathway 21.4286 6 no
GO:0010506 regulation of autophagy 21.4286 6 no
GO:0071900 regulation of protein serine/threonine kinase activity 21.4286 7 no
GO:0009891 positive regulation of biosynthetic process 21.4286 5 no
GO:0030162 regulation of proteolysis 21.4286 6 no
GO:0031401 positive regulation of protein modification process 21.4286 7 no
GO:0016050 vesicle organization 21.4286 5 no
GO:0031346 positive regulation of cell projection organization 21.4286 6 no
GO:1905475 regulation of protein localization to membrane 21.4286 6 no
GO:0001558 regulation of cell growth 21.4286 4 no
GO:0007010 cytoskeleton organization 21.4286 5 no
GO:0010720 positive regulation of cell development 21.4286 6 no
GO:0010942 positive regulation of cell death 21.4286 5 no
GO:0010975 regulation of neuron projection development 21.4286 7 no
GO:0030516 regulation of axon extension 21.4286 5 no
GO:0044089 positive regulation of cellular component biogenesis 21.4286 5 no
GO:0048638 regulation of developmental growth 21.4286 4 no
GO:0050767 regulation of neurogenesis 21.4286 6 no
GO:0050770 regulation of axonogenesis 21.4286 5 no
GO:0051960 regulation of nervous system development 21.4286 5 no
GO:0061387 regulation of extent of cell growth 21.4286 5 no
GO:0071310 cellular response to organic substance 21.4286 4 no
GO:0080135 regulation of cellular response to stress 21.4286 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 21.4286 6 no
GO:1901214 regulation of neuron death 21.4286 5 no
GO:0006796 phosphate-containing compound metabolic process 21.4286 4 no
GO:0071702 organic substance transport 21.4286 4 no
GO:0071705 nitrogen compound transport 21.4286 4 no
GO:0045596 negative regulation of cell differentiation 21.4286 5 no
GO:0051223 regulation of protein transport 21.4286 5 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
TAB2_HUMAN [view interactions] High throughput no yes
CTU1_HUMAN [view interactions] High throughput no no
MYCPP_HUMAN [view interactions] High throughput no no
TAB1_HUMAN [view interactions] High throughput no yes
CC85C_HUMAN [view interactions] High throughput no yes
FIBB_HUMAN [view entry] [view interactions] High throughput yes no
POPD3_HUMAN [view interactions] High throughput no no
CC121_HUMAN [view interactions] High throughput no no
CUL4B_HUMAN [view interactions] High throughput no yes
GORS1_HUMAN [view interactions] High throughput no yes
SODM_HUMAN [view entry] [view interactions] High throughput yes no
ZNF25_HUMAN [view interactions] High throughput no no
RPA34_HUMAN [view interactions] High throughput no yes
M3K7_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
CATZ_HUMAN [view interactions] High throughput no yes
FBX25_HUMAN [view interactions] High throughput no no
FCG2A_HUMAN [view interactions] High throughput no no
MFI_HUMAN [view interactions] High throughput no no
CD5R1_HUMAN [view entry] [view interactions] High throughput yes no
MBD5_HUMAN [view interactions] High throughput no no
SNR27_HUMAN [view interactions] High throughput no yes
AR6P6_HUMAN [view interactions] High throughput no yes
LACB2_HUMAN [view interactions] High throughput no yes
SCRN2_HUMAN [view interactions] High throughput no yes
COX10_HUMAN [view interactions] High throughput no yes
TR11B_HUMAN [view interactions] High throughput no no
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
HGS_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
NAGK_HUMAN [view interactions] High throughput no no
GDIA_HUMAN [view entry] [view interactions] High throughput yes yes
GNAI2_HUMAN [view entry] [view interactions] High throughput yes yes
HMGB3_HUMAN [view interactions] High throughput no no
SMAP_HUMAN [view interactions] High throughput no yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes