Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SCRN1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SCRN1_HUMAN
GO:0019900 kinase binding 30.4348 4 no
GO:0043169 cation binding 30.4348 4 no
GO:0046872 metal ion binding 30.4348 5 no
GO:0003779 actin binding 21.7391 4 no
GO:0044389 ubiquitin-like protein ligase binding 21.7391 4 no
GO:0001664 G protein-coupled receptor binding 21.7391 4 no
GO:0008234 cysteine-type peptidase activity 8.6957 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SCRN1_HUMAN
GO:0048522 positive regulation of cellular process 69.5652 4 no
GO:0048523 negative regulation of cellular process 65.2174 4 no
GO:0009966 regulation of signal transduction 65.2174 4 no
GO:0010646 regulation of cell communication 65.2174 4 no
GO:0051128 regulation of cellular component organization 56.5217 4 no
GO:0006996 organelle organization 56.5217 4 no
GO:0031323 regulation of cellular metabolic process 56.5217 4 no
GO:0008104 protein localization 52.1739 4 no
GO:0060255 regulation of macromolecule metabolic process 52.1739 4 no
GO:0044087 regulation of cellular component biogenesis 47.8261 4 no
GO:0080090 regulation of primary metabolic process 47.8261 4 no
GO:0009893 positive regulation of metabolic process 47.8261 4 no
GO:0051246 regulation of protein metabolic process 43.4783 5 no
GO:0022607 cellular component assembly 43.4783 4 no
GO:1902531 regulation of intracellular signal transduction 43.4783 5 no
GO:0048584 positive regulation of response to stimulus 43.4783 4 no
GO:0051049 regulation of transport 39.1304 4 yes
GO:0031399 regulation of protein modification process 39.1304 6 no
GO:0051130 positive regulation of cellular component organization 39.1304 5 no
GO:0031325 positive regulation of cellular metabolic process 39.1304 5 no
GO:0060627 regulation of vesicle-mediated transport 34.7826 4 yes
GO:0009889 regulation of biosynthetic process 34.7826 4 no
GO:0010468 regulation of gene expression 34.7826 6 no
GO:0010556 regulation of macromolecule biosynthetic process 34.7826 5 no
GO:0031326 regulation of cellular biosynthetic process 34.7826 5 no
GO:0032880 regulation of protein localization 34.7826 5 no
GO:0060341 regulation of cellular localization 34.7826 4 no
GO:0010604 positive regulation of macromolecule metabolic process 34.7826 5 no
GO:0009967 positive regulation of signal transduction 34.7826 5 no
GO:0009968 negative regulation of signal transduction 34.7826 5 no
GO:0010647 positive regulation of cell communication 34.7826 5 no
GO:0010648 negative regulation of cell communication 34.7826 5 no
GO:0023056 positive regulation of signaling 34.7826 4 no
GO:0023057 negative regulation of signaling 34.7826 4 no
GO:0048585 negative regulation of response to stimulus 34.7826 4 no
GO:0051094 positive regulation of developmental process 34.7826 4 no
GO:0006508 proteolysis 30.4348 4 yes
GO:0071702 organic substance transport 30.4348 4 no
GO:0071705 nitrogen compound transport 30.4348 4 no
GO:0009894 regulation of catabolic process 30.4348 4 no
GO:0019220 regulation of phosphate metabolic process 30.4348 6 no
GO:0022603 regulation of anatomical structure morphogenesis 30.4348 4 no
GO:0036211 protein modification process 30.4348 4 no
GO:0043067 regulation of programmed cell death 30.4348 4 no
GO:0043412 macromolecule modification 30.4348 4 no
GO:0051174 regulation of phosphorus metabolic process 30.4348 5 no
GO:0051129 negative regulation of cellular component organization 30.4348 5 no
GO:0051240 positive regulation of multicellular organismal process 30.4348 4 no
GO:0043933 protein-containing complex organization 30.4348 4 no
GO:0033365 protein localization to organelle 30.4348 5 no
GO:0009892 negative regulation of metabolic process 26.0870 4 no
GO:0010605 negative regulation of macromolecule metabolic process 26.0870 5 no
GO:0030030 cell projection organization 26.0870 4 no
GO:0031175 neuron projection development 26.0870 6 no
GO:0031324 negative regulation of cellular metabolic process 26.0870 5 no
GO:0033043 regulation of organelle organization 26.0870 5 no
GO:0042325 regulation of phosphorylation 26.0870 7 no
GO:0042981 regulation of apoptotic process 26.0870 5 no
GO:0043549 regulation of kinase activity 26.0870 5 no
GO:0044089 positive regulation of cellular component biogenesis 26.0870 5 no
GO:0051338 regulation of transferase activity 26.0870 4 no
GO:0051493 regulation of cytoskeleton organization 26.0870 6 no
GO:0120036 plasma membrane bounded cell projection organization 26.0870 5 no
GO:1902903 regulation of supramolecular fiber organization 26.0870 5 no
GO:0072657 protein localization to membrane 26.0870 4 no
GO:0010038 response to metal ion 26.0870 4 no
GO:0065003 protein-containing complex assembly 26.0870 5 no
GO:0051093 negative regulation of developmental process 26.0870 4 no
GO:0051247 positive regulation of protein metabolic process 26.0870 6 no
GO:0050804 modulation of chemical synaptic transmission 26.0870 5 no
GO:0099177 regulation of trans-synaptic signaling 26.0870 4 no
GO:0015031 protein transport 21.7391 4 no
GO:0001932 regulation of protein phosphorylation 21.7391 7 no
GO:0006355 regulation of DNA-templated transcription 21.7391 7 no
GO:0007010 cytoskeleton organization 21.7391 5 no
GO:0009890 negative regulation of biosynthetic process 21.7391 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.7391 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 21.7391 5 no
GO:0031327 negative regulation of cellular biosynthetic process 21.7391 6 no
GO:0031344 regulation of cell projection organization 21.7391 5 no
GO:0032956 regulation of actin cytoskeleton organization 21.7391 5 no
GO:0032970 regulation of actin filament-based process 21.7391 4 no
GO:0043254 regulation of protein-containing complex assembly 21.7391 5 no
GO:0045595 regulation of cell differentiation 21.7391 4 no
GO:0051252 regulation of RNA metabolic process 21.7391 5 no
GO:0070201 regulation of establishment of protein localization 21.7391 6 no
GO:1903829 positive regulation of protein localization 21.7391 5 no
GO:1905475 regulation of protein localization to membrane 21.7391 6 no
GO:2001141 regulation of RNA biosynthetic process 21.7391 6 no
GO:0009891 positive regulation of biosynthetic process 21.7391 5 no
GO:0031328 positive regulation of cellular biosynthetic process 21.7391 6 no
GO:0061024 membrane organization 21.7391 4 no
GO:0043066 negative regulation of apoptotic process 21.7391 6 no
GO:0043069 negative regulation of programmed cell death 21.7391 5 no
GO:0043408 regulation of MAPK cascade 21.7391 6 no
GO:0051241 negative regulation of multicellular organismal process 21.7391 4 no
GO:0071310 cellular response to organic substance 21.7391 4 no
GO:0080134 regulation of response to stress 21.7391 4 no
GO:1902533 positive regulation of intracellular signal transduction 21.7391 6 no
GO:2000026 regulation of multicellular organismal development 21.7391 4 no
GO:0007005 mitochondrion organization 21.7391 5 no
GO:2000377 regulation of reactive oxygen species metabolic process 21.7391 5 no
GO:0030162 regulation of proteolysis 21.7391 6 no
GO:0051248 negative regulation of protein metabolic process 21.7391 6 no
GO:0050890 cognition 21.7391 4 no
GO:0043086 negative regulation of catalytic activity 21.7391 4 no
GO:0046903 secretion 8.6957 4 yes
GO:0098693 regulation of synaptic vesicle cycle 8.6957 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
CC85C_HUMAN [view interactions] High throughput no yes
TAB1_HUMAN [view interactions] High throughput no yes
MYCPP_HUMAN [view interactions] High throughput no no
CTU1_HUMAN [view interactions] High throughput no no
TAB2_HUMAN [view interactions] High throughput no yes
FIBB_HUMAN [view entry] [view interactions] High throughput yes no
CC121_HUMAN [view interactions] High throughput no no
POPD3_HUMAN [view interactions] High throughput no no
CUL4B_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
DYR1A_HUMAN [view interactions] High throughput no yes
GORS1_HUMAN [view interactions] High throughput no yes
SODM_HUMAN [view entry] [view interactions] High throughput yes no
ZNF25_HUMAN [view interactions] High throughput no no
RPA34_HUMAN [view interactions] High throughput no yes
M3K7_HUMAN [view interactions] High throughput no yes
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
CATZ_HUMAN [view interactions] High throughput no yes
FBX25_HUMAN [view interactions] High throughput no no
FCG2A_HUMAN [view interactions] High throughput no no
MFI_HUMAN [view interactions] High throughput no no
CD5R1_HUMAN [view entry] [view interactions] High throughput yes no
MBD5_HUMAN [view interactions] High throughput no no
SNR27_HUMAN [view interactions] High throughput no yes
AR6P6_HUMAN [view interactions] High throughput no yes
LACB2_HUMAN [view interactions] High throughput no yes
SCRN2_HUMAN [view interactions] High throughput no yes
COX10_HUMAN [view interactions] High throughput no yes
TR11B_HUMAN [view interactions] High throughput no no
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
UBP48_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
SPPL3_HUMAN [view interactions] High throughput no no
HGS_HUMAN [view entry] [view interactions] High throughput yes yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
NAGK_HUMAN [view interactions] High throughput no no
GDIA_HUMAN [view entry] [view interactions] High throughput yes yes
GNAI2_HUMAN [view entry] [view interactions] High throughput yes yes
HMGB3_HUMAN [view interactions] High throughput no no
SMAP_HUMAN [view interactions] High throughput no yes
UCHL1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM3_HUMAN [view interactions] High throughput no no
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
TAF6_HUMAN [view interactions] High throughput no no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
ACTS_HUMAN [view interactions] High throughput no no
SPTB2_HUMAN [view entry] [view interactions] High throughput yes yes
ANM1_HUMAN [view interactions] High throughput no yes
HOIL1_HUMAN [view interactions] High throughput no no
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
NRX1A_HUMAN [view entry] [view interactions] High throughput yes no
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no