SNX12_HUMAN
Evidence for PS localization
Functions
May be involved in several stages of intracellular trafficking. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SNX12_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 26.6667 | 4 | no |
| GO:0005524 | ATP binding | 23.3333 | 5 | no |
| GO:0017076 | purine nucleotide binding | 23.3333 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.3333 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 23.3333 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.3333 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.3333 | 4 | no |
| GO:0035091 | phosphatidylinositol binding | 20.0000 | 4 | yes |
| GO:1901981 | phosphatidylinositol phosphate binding | 13.3333 | 5 | yes |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | 10.0000 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SNX12_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 63.3333 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 63.3333 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 63.3333 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 60.0000 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 56.6667 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.6667 | 4 | no |
| GO:0008104 | protein localization | 46.6667 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 46.6667 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 43.3333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.3333 | 4 | no |
| GO:0010468 | regulation of gene expression | 43.3333 | 5 | yes |
| GO:0051049 | regulation of transport | 40.0000 | 4 | yes |
| GO:0009894 | regulation of catabolic process | 40.0000 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 36.6667 | 5 | yes |
| GO:0071702 | organic substance transport | 36.6667 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 36.6667 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 36.6667 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.6667 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 36.6667 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.6667 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.6667 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 36.6667 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 33.3333 | 5 | yes |
| GO:0006996 | organelle organization | 33.3333 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | yes |
| GO:0015031 | protein transport | 33.3333 | 4 | yes |
| GO:0016197 | endosomal transport | 33.3333 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 30.0000 | 6 | yes |
| GO:0060341 | regulation of cellular localization | 30.0000 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.0000 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.0000 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 30.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.0000 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 30.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.0000 | 5 | no |
| GO:0032880 | regulation of protein localization | 30.0000 | 5 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 26.6667 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.6667 | 6 | no |
| GO:0033043 | regulation of organelle organization | 26.6667 | 5 | no |
| GO:0010941 | regulation of cell death | 26.6667 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.6667 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.6667 | 4 | no |
| GO:0051050 | positive regulation of transport | 26.6667 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 26.6667 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.6667 | 6 | no |
| GO:0070201 | regulation of establishment of protein localization | 23.3333 | 6 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.3333 | 6 | no |
| GO:0010638 | positive regulation of organelle organization | 23.3333 | 6 | no |
| GO:0022607 | cellular component assembly | 23.3333 | 4 | no |
| GO:0060548 | negative regulation of cell death | 23.3333 | 5 | no |
| GO:0006886 | intracellular protein transport | 23.3333 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.3333 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.3333 | 5 | no |
| GO:0023057 | negative regulation of signaling | 23.3333 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 23.3333 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 23.3333 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.3333 | 5 | no |
| GO:0016482 | cytosolic transport | 23.3333 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 20.0000 | 4 | yes |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 20.0000 | 4 | yes |
| GO:0032456 | endocytic recycling | 20.0000 | 5 | yes |
| GO:0042147 | retrograde transport, endosome to Golgi | 20.0000 | 5 | yes |
| GO:0042176 | regulation of protein catabolic process | 20.0000 | 5 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 16.6667 | 6 | yes |
| GO:0051223 | regulation of protein transport | 16.6667 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 16.6667 | 5 | yes |
| GO:0032386 | regulation of intracellular transport | 16.6667 | 5 | yes |
| GO:0051051 | negative regulation of transport | 13.3333 | 4 | yes |
| GO:0010629 | negative regulation of gene expression | 13.3333 | 6 | yes |
| GO:0048193 | Golgi vesicle transport | 10.0000 | 5 | yes |
| GO:1903649 | regulation of cytoplasmic transport | 10.0000 | 6 | yes |
| GO:1903828 | negative regulation of protein localization | 10.0000 | 5 | yes |
| GO:2000641 | regulation of early endosome to late endosome transport | 10.0000 | 5 | yes |
| GO:0030100 | regulation of endocytosis | 10.0000 | 5 | yes |
| GO:0032387 | negative regulation of intracellular transport | 10.0000 | 5 | yes |
| GO:0051224 | negative regulation of protein transport | 6.6667 | 5 | yes |
| GO:1903650 | negative regulation of cytoplasmic transport | 6.6667 | 6 | yes |
| GO:1904950 | negative regulation of establishment of protein localization | 6.6667 | 6 | yes |
| GO:2000642 | negative regulation of early endosome to late endosome transport | 6.6667 | 6 | yes |
| GO:0030162 | regulation of proteolysis | 6.6667 | 6 | yes |
| GO:0034499 | late endosome to Golgi transport | 6.6667 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| AR6P1_HUMAN | [view interactions] | High throughput | no | yes |
| RPRM_HUMAN | [view interactions] | High throughput | no | no |
| FKBP7_HUMAN | [view interactions] | High throughput | no | yes |
| ANGT_HUMAN | [view interactions] | High throughput | no | no |
| KLKB1_HUMAN | [view interactions] | High throughput | no | no |
| LIPL_HUMAN | [view interactions] | High throughput | no | no |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PACN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BORG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FACC1_HUMAN | [view interactions] | High throughput | no | no |
| TMTC4_HUMAN | [view interactions] | High throughput | no | yes |
| EVA1C_HUMAN | [view interactions] | High throughput | no | yes |
| F217B_HUMAN | [view interactions] | High throughput | no | yes |
| NTNG1_HUMAN | [view interactions] | High throughput | no | no |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| SNTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTN23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDEAS_HUMAN | [view interactions] | High throughput | no | yes |
| VPS35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICLN_HUMAN | [view interactions] | High throughput | no | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GNPI2_HUMAN | [view interactions] | High throughput | no | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
| APT_HUMAN | [view interactions] | High throughput | no | yes |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GILT_HUMAN | [view interactions] | High throughput | no | no |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P4R3A_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNX6_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNX17_HUMAN | [view interactions] | Computational | no | yes |
| VP26B_HUMAN | [view interactions] | Computational | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNX5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |