TAGL2_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in TAGL2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 22.0588 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0588 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.0588 | 4 | no |
| GO:0003779 | actin binding | 20.5882 | 4 | no |
| GO:0045296 | cadherin binding | 19.1176 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in TAGL2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 54.4118 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.5294 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 48.5294 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 45.5882 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 45.5882 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.5882 | 4 | no |
| GO:0010646 | regulation of cell communication | 39.7059 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.2353 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 38.2353 | 4 | no |
| GO:0051049 | regulation of transport | 36.7647 | 4 | no |
| GO:0009966 | regulation of signal transduction | 33.8235 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.8235 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 33.8235 | 5 | no |
| GO:0008104 | protein localization | 33.8235 | 4 | no |
| GO:0006996 | organelle organization | 32.3529 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 30.8824 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.8824 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.8824 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.8824 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.4118 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 29.4118 | 5 | no |
| GO:0060341 | regulation of cellular localization | 29.4118 | 4 | no |
| GO:0071702 | organic substance transport | 29.4118 | 4 | no |
| GO:0032880 | regulation of protein localization | 27.9412 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.4706 | 5 | no |
| GO:0009894 | regulation of catabolic process | 26.4706 | 4 | no |
| GO:0022607 | cellular component assembly | 25.0000 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0010941 | regulation of cell death | 25.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 23.5294 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.5294 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 23.5294 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.5294 | 6 | no |
| GO:0071310 | cellular response to organic substance | 23.5294 | 4 | no |
| GO:0033043 | regulation of organelle organization | 23.5294 | 5 | no |
| GO:0071705 | nitrogen compound transport | 23.5294 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 23.5294 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.0588 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 22.0588 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 22.0588 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.0588 | 4 | no |
| GO:0036211 | protein modification process | 22.0588 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.0588 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 22.0588 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.0588 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 22.0588 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.0588 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.0588 | 5 | no |
| GO:0015031 | protein transport | 22.0588 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.0588 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 22.0588 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 22.0588 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 20.5882 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.5882 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.5882 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.5882 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.5882 | 4 | no |
| GO:0060548 | negative regulation of cell death | 20.5882 | 5 | no |
| GO:0030855 | epithelial cell differentiation | 7.3529 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in TAGL2_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 4.4118 | 3 | no |
| DOID:870 | neuropathy | 4.4118 | 4 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 2.9412 | 7 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.9412 | 6 | no |
| DOID:114 | heart disease | 2.9412 | 3 | no |
| DOID:440 | neuromuscular disease | 2.9412 | 5 | no |
| DOID:65 | connective tissue disease | 2.9412 | 3 | no |
| DOID:331 | central nervous system disease | 2.9412 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| UBP1_HUMAN | [view interactions] | High throughput | no | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| TIGD6_HUMAN | [view interactions] | High throughput | no | no |
| IFFO2_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD2_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| ACATN_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC1_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SOS2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIE1_HUMAN | [view interactions] | High throughput | no | no |
| TXD16_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG5_HUMAN | [view interactions] | High throughput | no | no |
| PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
| EIF1B_HUMAN | [view interactions] | High throughput | no | no |
| PINX1_HUMAN | [view interactions] | High throughput | no | yes |
| TRM7_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| ARP6_HUMAN | [view interactions] | High throughput | no | yes |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| EHD2_HUMAN | [view interactions] | High throughput | no | no |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| GDAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK068_HUMAN | [view interactions] | High throughput | no | yes |
| NUP43_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
| DNLI4_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| IFFO1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| TISD_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS21_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| INS_HUMAN | [view interactions] | High throughput | no | no |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VSIG8_HUMAN | [view interactions] | High throughput | no | no |
| SNH28_HUMAN | [view interactions] | High throughput | no | no |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| PSA5_HUMAN | [view interactions] | High throughput | no | yes |
| ELOV1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| CPLX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX36_HUMAN | [view interactions] | High throughput | no | yes |
| RUXF_HUMAN | [view interactions] | High throughput | no | no |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL8A_HUMAN | [view interactions] | High throughput | no | no |
| ATOX1_HUMAN | [view interactions] | High throughput | no | no |
| NNRD_HUMAN | [view interactions] | High throughput | no | yes |
| CLIC3_HUMAN | [view interactions] | High throughput | no | no |
| CLIC4_HUMAN | [view interactions] | High throughput | no | no |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| ECI1_HUMAN | [view interactions] | High throughput | no | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FABPH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FABP5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FABP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKB1A_HUMAN | [view interactions] | High throughput | no | yes |
| FKB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| C1TM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTF2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| MYP2_HUMAN | [view interactions] | High throughput | no | no |
| SERC_HUMAN | [view interactions] | High throughput | no | yes |
| RAB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COTL1_HUMAN | [view interactions] | High throughput | no | yes |
| DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
| IF5A2_HUMAN | [view interactions] | High throughput | no | yes |
| IF5AL_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FKBP2_HUMAN | [view interactions] | High throughput | no | yes |
| GDIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTO2_HUMAN | [view interactions] | High throughput | no | no |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| HSDL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP74_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| NDKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRE_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2C_HUMAN | [view interactions] | High throughput | no | yes |
| UB2V1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFC1_HUMAN | [view interactions] | High throughput | no | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TKTL2_HUMAN | [view interactions] | High throughput | no | no |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ENDD1_HUMAN | [view interactions] | Computational | no | yes |
| WDR1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HABP4_HUMAN | [view interactions] | Computational | no | yes |
| ANXA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PLEK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TBA4A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FLNA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| TLN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BRPF3_HUMAN | [view interactions] | Computational | no | yes |
| STXB2_HUMAN | [view interactions] | Computational | no | no |
| VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MANF_HUMAN | [view interactions] | Computational | no | yes |