Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FABP7_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FABP7_HUMAN
GO:0005509 calcium ion binding 33.3333 5 no
GO:0046872 metal ion binding 33.3333 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in FABP7_HUMAN
GO:0048523 negative regulation of cellular process 66.6667 4 yes
GO:0006355 regulation of DNA-templated transcription 50.0000 6 no
GO:0009889 regulation of biosynthetic process 50.0000 4 no
GO:0009892 negative regulation of metabolic process 50.0000 4 no
GO:0010468 regulation of gene expression 50.0000 5 no
GO:0010556 regulation of macromolecule biosynthetic process 50.0000 5 no
GO:0010605 negative regulation of macromolecule metabolic process 50.0000 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 50.0000 5 no
GO:0031323 regulation of cellular metabolic process 50.0000 4 no
GO:0031324 negative regulation of cellular metabolic process 50.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 50.0000 5 no
GO:0051171 regulation of nitrogen compound metabolic process 50.0000 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 50.0000 5 no
GO:0051252 regulation of RNA metabolic process 50.0000 5 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:1903506 regulation of nucleic acid-templated transcription 50.0000 7 no
GO:2001141 regulation of RNA biosynthetic process 50.0000 6 no
GO:0008285 negative regulation of cell population proliferation 33.3333 5 yes
GO:0042127 regulation of cell population proliferation 33.3333 4 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 33.3333 8 no
GO:0006357 regulation of transcription by RNA polymerase II 33.3333 7 no
GO:0006873 cellular ion homeostasis 33.3333 4 no
GO:0006875 cellular metal ion homeostasis 33.3333 6 no
GO:0009890 negative regulation of biosynthetic process 33.3333 5 no
GO:0009893 positive regulation of metabolic process 33.3333 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0009968 negative regulation of signal transduction 33.3333 5 no
GO:0010243 response to organonitrogen compound 33.3333 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 33.3333 6 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0010646 regulation of cell communication 33.3333 4 no
GO:0010648 negative regulation of cell communication 33.3333 5 no
GO:0010941 regulation of cell death 33.3333 4 no
GO:0010959 regulation of metal ion transport 33.3333 6 no
GO:0023057 negative regulation of signaling 33.3333 4 no
GO:0030003 cellular cation homeostasis 33.3333 5 no
GO:0031327 negative regulation of cellular biosynthetic process 33.3333 6 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0031401 positive regulation of protein modification process 33.3333 7 no
GO:0042981 regulation of apoptotic process 33.3333 6 no
GO:0043066 negative regulation of apoptotic process 33.3333 7 no
GO:0043067 regulation of programmed cell death 33.3333 5 no
GO:0043069 negative regulation of programmed cell death 33.3333 6 no
GO:0043269 regulation of ion transport 33.3333 5 no
GO:0043433 negative regulation of DNA-binding transcription factor activity 33.3333 4 no
GO:0043523 regulation of neuron apoptotic process 33.3333 6 no
GO:0045892 negative regulation of DNA-templated transcription 33.3333 7 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 33.3333 6 no
GO:0048585 negative regulation of response to stimulus 33.3333 4 no
GO:0048878 chemical homeostasis 33.3333 4 no
GO:0050801 ion homeostasis 33.3333 5 no
GO:0051049 regulation of transport 33.3333 4 no
GO:0051050 positive regulation of transport 33.3333 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0051253 negative regulation of RNA metabolic process 33.3333 6 no
GO:0051924 regulation of calcium ion transport 33.3333 7 no
GO:0055065 metal ion homeostasis 33.3333 7 no
GO:0055080 cation homeostasis 33.3333 6 no
GO:0060548 negative regulation of cell death 33.3333 5 no
GO:0098771 inorganic ion homeostasis 33.3333 6 no
GO:1901214 regulation of neuron death 33.3333 5 no
GO:1902531 regulation of intracellular signal transduction 33.3333 5 no
GO:1902532 negative regulation of intracellular signal transduction 33.3333 6 no
GO:1902679 negative regulation of RNA biosynthetic process 33.3333 7 no
GO:1903507 negative regulation of nucleic acid-templated transcription 33.3333 8 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
TNS2_HUMAN [view interactions] High throughput no no
GPR37_HUMAN [view interactions] High throughput no no
GRN_HUMAN [view interactions] High throughput no no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
SPRE1_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
PEMT_HUMAN [view interactions] High throughput no yes
ALDR_HUMAN [view interactions] High throughput no no
HINT1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
TAGL_HUMAN [view interactions] High throughput no no
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
TAGL3_HUMAN [view entry] [view interactions] High throughput yes yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
TKTL2_HUMAN [view interactions] High throughput no no
PPIL3_HUMAN [view interactions] High throughput no yes
MAMD1_HUMAN [view interactions] Computational no no
MAML3_HUMAN [view interactions] Computational no yes
SUH_HUMAN [view interactions] Computational no yes
KAT2B_HUMAN [view interactions] Computational no yes
MAML1_HUMAN [view interactions] Computational no yes
EP300_HUMAN [view interactions] Computational no yes
NOTC3_HUMAN [view interactions] Computational no yes
KAT2A_HUMAN [view interactions] Computational no no
MAML2_HUMAN [view interactions] Computational no yes
SNW1_HUMAN [view interactions] Computational no yes
CBP_HUMAN [view interactions] Computational no yes