Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FABP7_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FABP7_HUMAN
GO:0043168 anion binding 36.3636 4 yes
GO:0043169 cation binding 36.3636 4 no
GO:0046872 metal ion binding 36.3636 5 no
GO:0003779 actin binding 27.2727 4 no
GO:0000287 magnesium ion binding 27.2727 6 no
GO:0031406 carboxylic acid binding 18.1818 4 yes
GO:0033293 monocarboxylic acid binding 18.1818 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in FABP7_HUMAN
GO:0048523 negative regulation of cellular process 54.5455 4 yes
GO:0010646 regulation of cell communication 45.4545 4 no
GO:0009892 negative regulation of metabolic process 45.4545 4 no
GO:0031323 regulation of cellular metabolic process 45.4545 4 no
GO:0006355 regulation of DNA-templated transcription 36.3636 7 no
GO:0009889 regulation of biosynthetic process 36.3636 4 no
GO:0009890 negative regulation of biosynthetic process 36.3636 5 no
GO:0009966 regulation of signal transduction 36.3636 4 no
GO:0010468 regulation of gene expression 36.3636 6 no
GO:0010556 regulation of macromolecule biosynthetic process 36.3636 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 36.3636 6 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 36.3636 5 no
GO:0031324 negative regulation of cellular metabolic process 36.3636 5 no
GO:0031326 regulation of cellular biosynthetic process 36.3636 5 no
GO:0031327 negative regulation of cellular biosynthetic process 36.3636 6 no
GO:0048522 positive regulation of cellular process 36.3636 4 no
GO:0051252 regulation of RNA metabolic process 36.3636 5 no
GO:0060255 regulation of macromolecule metabolic process 36.3636 4 no
GO:0080090 regulation of primary metabolic process 36.3636 4 no
GO:2001141 regulation of RNA biosynthetic process 36.3636 6 no
GO:0008285 negative regulation of cell population proliferation 27.2727 5 yes
GO:0042127 regulation of cell population proliferation 27.2727 4 yes
GO:0071702 organic substance transport 27.2727 4 yes
GO:0050804 modulation of chemical synaptic transmission 27.2727 5 no
GO:0099177 regulation of trans-synaptic signaling 27.2727 4 no
GO:0009893 positive regulation of metabolic process 27.2727 4 no
GO:0009968 negative regulation of signal transduction 27.2727 5 no
GO:0010604 positive regulation of macromolecule metabolic process 27.2727 5 no
GO:0010648 negative regulation of cell communication 27.2727 5 no
GO:0010959 regulation of metal ion transport 27.2727 6 no
GO:0023057 negative regulation of signaling 27.2727 4 no
GO:0030162 regulation of proteolysis 27.2727 6 no
GO:0031399 regulation of protein modification process 27.2727 6 no
GO:0031401 positive regulation of protein modification process 27.2727 7 no
GO:0042981 regulation of apoptotic process 27.2727 5 no
GO:0043066 negative regulation of apoptotic process 27.2727 6 no
GO:0043067 regulation of programmed cell death 27.2727 4 no
GO:0043069 negative regulation of programmed cell death 27.2727 5 no
GO:0043269 regulation of monoatomic ion transport 27.2727 5 no
GO:0043523 regulation of neuron apoptotic process 27.2727 6 no
GO:0048585 negative regulation of response to stimulus 27.2727 4 no
GO:0051049 regulation of transport 27.2727 4 no
GO:0051246 regulation of protein metabolic process 27.2727 5 no
GO:0051247 positive regulation of protein metabolic process 27.2727 6 no
GO:0051248 negative regulation of protein metabolic process 27.2727 6 no
GO:0051924 regulation of calcium ion transport 27.2727 7 no
GO:1902531 regulation of intracellular signal transduction 27.2727 5 no
GO:0000122 negative regulation of transcription by RNA polymerase II 27.2727 9 no
GO:0006357 regulation of transcription by RNA polymerase II 27.2727 8 no
GO:0009894 regulation of catabolic process 27.2727 4 no
GO:0045892 negative regulation of DNA-templated transcription 27.2727 8 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 27.2727 5 no
GO:0048584 positive regulation of response to stimulus 27.2727 4 no
GO:0051253 negative regulation of RNA metabolic process 27.2727 6 no
GO:1902679 negative regulation of RNA biosynthetic process 27.2727 7 no
GO:0097435 supramolecular fiber organization 27.2727 4 no
GO:0006869 lipid transport 18.1818 5 yes
GO:0007399 nervous system development 18.1818 4 yes
GO:0015711 organic anion transport 18.1818 5 yes
GO:0015718 monocarboxylic acid transport 18.1818 7 yes
GO:0015849 organic acid transport 18.1818 5 yes
GO:0015908 fatty acid transport 18.1818 6 yes
GO:0046942 carboxylic acid transport 18.1818 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
FABP7_HUMAN [view entry] [view interactions] Low throughput yes no
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
TENS2_HUMAN [view interactions] High throughput no no
GPR37_HUMAN [view interactions] High throughput no no
GRN_HUMAN [view interactions] High throughput no no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
SPRE1_HUMAN [view interactions] High throughput no yes
RN123_HUMAN [view interactions] High throughput no yes
PEMT_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
ALDR_HUMAN [view interactions] High throughput no no
HINT1_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
TAGL_HUMAN [view interactions] High throughput no no
TAGL2_HUMAN [view entry] [view interactions] High throughput yes no
TAGL3_HUMAN [view entry] [view interactions] High throughput yes yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
TKTL2_HUMAN [view interactions] High throughput no no
PPIL3_HUMAN [view interactions] High throughput no yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
BACD1_HUMAN [view interactions] High throughput no no
RHEB_HUMAN [view entry] [view interactions] High throughput yes yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no