PGK1_HUMAN
Evidence for PS localization
Functions
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed, PubMed). In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed). May play a role in sperm motility (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 88 | Leu | Pro | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 158 | Gly | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 164 | Asp | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 206 | Arg | Pro | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 252 | Glu | Ala | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 266 | Val | Met | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 285 | Asp | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 315 | Asp | Asn | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 316 | Cys | Arg | Phosphoglyceratekinase1deficiency(PGK1D) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PGK1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 35.5932 | 4 | no |
| GO:0019900 | kinase binding | 27.1186 | 4 | no |
| GO:0019901 | protein kinase binding | 23.7288 | 5 | no |
| GO:0017076 | purine nucleotide binding | 22.0339 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 20.3390 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.3390 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 15.2542 | 5 | yes |
| GO:0005524 | ATP binding | 13.5593 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 13.5593 | 5 | yes |
| GO:0016301 | kinase activity | 9.3220 | 4 | yes |
| GO:0015036 | disulfide oxidoreductase activity | 1.6949 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PGK1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 49.1525 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.4576 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 44.9153 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 44.9153 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 42.3729 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 40.6780 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 37.2881 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.4407 | 5 | no |
| GO:0010646 | regulation of cell communication | 35.5932 | 4 | no |
| GO:0010468 | regulation of gene expression | 33.8983 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 32.2034 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 32.2034 | 5 | no |
| GO:0009966 | regulation of signal transduction | 31.3559 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.5085 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.6610 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 29.6610 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 29.6610 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.9661 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.1186 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 27.1186 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.1186 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.1186 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.2712 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.4237 | 6 | no |
| GO:0022607 | cellular component assembly | 25.4237 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.7288 | 4 | yes |
| GO:0010941 | regulation of cell death | 23.7288 | 4 | no |
| GO:0008104 | protein localization | 22.0339 | 4 | no |
| GO:0051049 | regulation of transport | 22.0339 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.0339 | 5 | no |
| GO:0006996 | organelle organization | 22.0339 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 22.0339 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.0339 | 4 | no |
| GO:0060341 | regulation of cellular localization | 21.1864 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.1864 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.1864 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.1864 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 21.1864 | 6 | no |
| GO:0043412 | macromolecule modification | 21.1864 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 20.3390 | 6 | no |
| GO:0031399 | regulation of protein modification process | 20.3390 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 20.3390 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.3390 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 20.3390 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.3390 | 6 | no |
| GO:0036211 | protein modification process | 20.3390 | 4 | no |
| GO:0016310 | phosphorylation | 19.4915 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 18.6441 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 18.6441 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 17.7966 | 6 | yes |
| GO:0009117 | nucleotide metabolic process | 15.2542 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 15.2542 | 4 | yes |
| GO:0016052 | carbohydrate catabolic process | 13.5593 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 13.5593 | 4 | yes |
| GO:0006090 | pyruvate metabolic process | 13.5593 | 7 | yes |
| GO:0009132 | nucleoside diphosphate metabolic process | 12.7119 | 5 | yes |
| GO:0009135 | purine nucleoside diphosphate metabolic process | 12.7119 | 6 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 12.7119 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 12.7119 | 6 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 12.7119 | 6 | yes |
| GO:0009179 | purine ribonucleoside diphosphate metabolic process | 12.7119 | 7 | yes |
| GO:0009185 | ribonucleoside diphosphate metabolic process | 12.7119 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 12.7119 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 12.7119 | 7 | yes |
| GO:0009259 | ribonucleotide metabolic process | 12.7119 | 5 | yes |
| GO:0046031 | ADP metabolic process | 12.7119 | 7 | yes |
| GO:0046034 | ATP metabolic process | 12.7119 | 7 | yes |
| GO:0046939 | nucleotide phosphorylation | 12.7119 | 6 | yes |
| GO:0072521 | purine-containing compound metabolic process | 12.7119 | 4 | yes |
| GO:0006096 | glycolytic process | 12.7119 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 12.7119 | 5 | yes |
| GO:0006165 | nucleoside diphosphate phosphorylation | 12.7119 | 6 | yes |
| GO:0006757 | ATP generation from ADP | 12.7119 | 4 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 11.0169 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 10.1695 | 4 | yes |
| GO:0019318 | hexose metabolic process | 9.3220 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 8.4746 | 4 | yes |
| GO:0006006 | glucose metabolic process | 7.6271 | 5 | yes |
| GO:0006508 | proteolysis | 7.6271 | 4 | yes |
| GO:0051093 | negative regulation of developmental process | 6.7797 | 4 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 5.9322 | 4 | yes |
| GO:0046364 | monosaccharide biosynthetic process | 5.9322 | 4 | yes |
| GO:0030855 | epithelial cell differentiation | 5.0847 | 4 | yes |
| GO:0019319 | hexose biosynthetic process | 4.2373 | 5 | yes |
| GO:0036293 | response to decreased oxygen levels | 4.2373 | 4 | yes |
| GO:0006094 | gluconeogenesis | 4.2373 | 6 | yes |
| GO:0036294 | cellular response to decreased oxygen levels | 2.5424 | 5 | yes |
| GO:0045765 | regulation of angiogenesis | 2.5424 | 5 | yes |
| GO:0071453 | cellular response to oxygen levels | 2.5424 | 4 | yes |
| GO:0071456 | cellular response to hypoxia | 2.5424 | 4 | yes |
| GO:1901342 | regulation of vasculature development | 2.5424 | 5 | yes |
| GO:0016485 | protein processing | 1.6949 | 5 | yes |
| GO:0016525 | negative regulation of angiogenesis | 1.6949 | 6 | yes |
| GO:0051604 | protein maturation | 1.6949 | 4 | yes |
| GO:1901343 | negative regulation of vasculature development | 1.6949 | 5 | yes |
| GO:2000181 | negative regulation of blood vessel morphogenesis | 1.6949 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in PGK1_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 3.3898 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.3898 | 5 | no |
| DOID:114 | heart disease | 3.3898 | 3 | no |
| DOID:1289 | neurodegenerative disease | 2.5424 | 4 | no |
| DOID:331 | central nervous system disease | 2.5424 | 3 | no |
| DOID:2843 | long QT syndrome | 1.6949 | 6 | no |
| DOID:65 | connective tissue disease | 1.6949 | 3 | no |
| DOID:0080000 | muscular disease | 1.6949 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 1.6949 | 6 | no |
| DOID:423 | myopathy | 1.6949 | 5 | no |
| DOID:66 | muscle tissue disease | 1.6949 | 4 | no |
| DOID:0050890 | synucleinopathy | 1.6949 | 5 | no |
| DOID:0060894 | early-onset Parkinsons disease | 1.6949 | 7 | no |
| DOID:14330 | Parkinsons disease | 1.6949 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RFIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
| PK3C3_HUMAN | [view interactions] | Low throughput | no | yes |
| BAKOR_HUMAN | [view interactions] | Low throughput | no | yes |
| NAA10_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC7_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TENA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STAT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HDAC3_HUMAN | [view interactions] | Low throughput | no | yes |
| ELP3_HUMAN | [view interactions] | Low throughput | no | no |
| NEK7_HUMAN | [view interactions] | Low throughput | no | yes |
| PGAM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HS105_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MCM2_HUMAN | [view interactions] | Low throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| UCK1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STMN1_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| PTMS_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| YAF2_HUMAN | [view interactions] | High throughput | no | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBRS_HUMAN | [view interactions] | High throughput | no | no |
| PCGF3_HUMAN | [view interactions] | High throughput | no | yes |
| PCGF5_HUMAN | [view interactions] | High throughput | no | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP6_HUMAN | [view interactions] | High throughput | no | yes |
| SYCM_HUMAN | [view interactions] | High throughput | no | yes |
| COQ2_HUMAN | [view interactions] | High throughput | no | yes |
| COX16_HUMAN | [view interactions] | High throughput | no | no |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| RT63_HUMAN | [view interactions] | High throughput | no | yes |
| RM10_HUMAN | [view interactions] | High throughput | no | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| RM33_HUMAN | [view interactions] | High throughput | no | yes |
| RM37_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| RT11_HUMAN | [view interactions] | High throughput | no | yes |
| RT21_HUMAN | [view interactions] | High throughput | no | no |
| RT30_HUMAN | [view interactions] | High throughput | no | yes |
| PAPD1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | High throughput | no | yes |
| NTF2_HUMAN | [view interactions] | High throughput | no | yes |
| 6PGD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMAC1_HUMAN | [view interactions] | High throughput | no | no |
| WDR61_HUMAN | [view interactions] | High throughput | no | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| UBE3A_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HTSF1_HUMAN | [view interactions] | High throughput | no | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BOLA2_HUMAN | [view interactions] | High throughput | no | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| AK1BA_HUMAN | [view interactions] | High throughput | no | no |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| MTND_HUMAN | [view interactions] | High throughput | no | yes |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| PYGL_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAKG2_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKG1_HUMAN | [view interactions] | High throughput | no | no |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRBF2_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FOXO3_HUMAN | [view interactions] | High throughput | no | yes |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIX_HUMAN | [view interactions] | High throughput | no | no |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| RFX5_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPA_HUMAN | [view interactions] | High throughput | no | no |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGK2_HUMAN | [view interactions] | High throughput | no | no |
| RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHOC2_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG5_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| CBX3_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK_HUMAN | [view interactions] | High throughput | no | no |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK068_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| ASB9_HUMAN | [view interactions] | High throughput | no | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| KPYR_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PMGE_HUMAN | [view interactions] | Computational | no | no |
| PFKAL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PGAM4_HUMAN | [view interactions] | Computational | no | no |
| A0A2U3TZM8_HUMAN | [view interactions] | Computational | no | no |
| PFKAM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAB28_HUMAN | [view interactions] | Computational | no | yes |
| ENO4_HUMAN | [view interactions] | Computational | no | no |
| G3PT_HUMAN | [view interactions] | Computational | no | no |