PGK1_HUMAN
Evidence for PS localization
Functions
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed, PubMed). In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed). May play a role in sperm motility (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 88 | Leu | Pro | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 158 | Gly | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 164 | Asp | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 206 | Arg | Pro | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 252 | Glu | Ala | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 266 | Val | Met | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 285 | Asp | Val | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 315 | Asp | Asn | Phosphoglyceratekinase1deficiency(PGK1D) | - |
| 316 | Cys | Arg | Phosphoglyceratekinase1deficiency(PGK1D) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PGK1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 37.8788 | 4 | no |
| GO:0019900 | kinase binding | 24.2424 | 4 | no |
| GO:0000166 | nucleotide binding | 23.4848 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 23.4848 | 5 | yes |
| GO:0043168 | anion binding | 22.7273 | 4 | yes |
| GO:0043169 | cation binding | 21.2121 | 4 | no |
| GO:0046872 | metal ion binding | 21.2121 | 5 | no |
| GO:0019901 | protein kinase binding | 21.2121 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 20.4545 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 20.4545 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 17.4242 | 6 | yes |
| GO:0005524 | ATP binding | 14.3939 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 14.3939 | 5 | yes |
| GO:0016301 | kinase activity | 8.3333 | 4 | yes |
| GO:0015036 | disulfide oxidoreductase activity | 1.5152 | 4 | yes |
| GO:0043531 | ADP binding | 1.5152 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PGK1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 52.2727 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 47.7273 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 47.7273 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.4545 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 43.9394 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 39.3939 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 39.3939 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.6364 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.6364 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 38.6364 | 5 | no |
| GO:0010468 | regulation of gene expression | 37.1212 | 6 | no |
| GO:0010646 | regulation of cell communication | 37.1212 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 34.8485 | 4 | no |
| GO:0009966 | regulation of signal transduction | 33.3333 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 32.5758 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.8182 | 5 | no |
| GO:0022607 | cellular component assembly | 31.0606 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.3030 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 30.3030 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.5455 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.5455 | 4 | no |
| GO:0006996 | organelle organization | 28.0303 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 27.2727 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 26.5152 | 4 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.5152 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 26.5152 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 25.7576 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.7576 | 6 | no |
| GO:0008104 | protein localization | 25.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 25.0000 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.0000 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 25.0000 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.2424 | 7 | no |
| GO:0009967 | positive regulation of signal transduction | 24.2424 | 5 | no |
| GO:0043412 | macromolecule modification | 24.2424 | 4 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.2424 | 6 | no |
| GO:0036211 | protein modification process | 23.4848 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 22.7273 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 22.7273 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 22.7273 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.9697 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.9697 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 21.9697 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.9697 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 21.9697 | 6 | no |
| GO:0009894 | regulation of catabolic process | 21.9697 | 4 | no |
| GO:0051049 | regulation of transport | 21.9697 | 4 | no |
| GO:0060341 | regulation of cellular localization | 21.9697 | 4 | no |
| GO:0031399 | regulation of protein modification process | 21.2121 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.2121 | 4 | no |
| GO:0080134 | regulation of response to stress | 20.4545 | 4 | no |
| GO:0006753 | nucleoside phosphate metabolic process | 17.4242 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 17.4242 | 5 | yes |
| GO:0006163 | purine nucleotide metabolic process | 16.6667 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 16.6667 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 16.6667 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 15.1515 | 4 | yes |
| GO:0009141 | nucleoside triphosphate metabolic process | 14.3939 | 5 | yes |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 14.3939 | 6 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 14.3939 | 6 | yes |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 14.3939 | 6 | yes |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 14.3939 | 7 | yes |
| GO:0009259 | ribonucleotide metabolic process | 14.3939 | 5 | yes |
| GO:0019752 | carboxylic acid metabolic process | 14.3939 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 14.3939 | 4 | yes |
| GO:0046034 | ATP metabolic process | 14.3939 | 7 | yes |
| GO:2000026 | regulation of multicellular organismal development | 14.3939 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 13.6364 | 6 | yes |
| GO:0019362 | pyridine nucleotide metabolic process | 12.1212 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 12.1212 | 4 | yes |
| GO:0034655 | nucleobase-containing compound catabolic process | 12.1212 | 4 | yes |
| GO:0046496 | nicotinamide nucleotide metabolic process | 12.1212 | 6 | yes |
| GO:0072524 | pyridine-containing compound metabolic process | 12.1212 | 4 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 12.1212 | 4 | yes |
| GO:0006508 | proteolysis | 11.3636 | 4 | yes |
| GO:0006090 | pyruvate metabolic process | 9.8485 | 7 | yes |
| GO:0009166 | nucleotide catabolic process | 9.8485 | 6 | yes |
| GO:0016052 | carbohydrate catabolic process | 9.8485 | 4 | yes |
| GO:0046434 | organophosphate catabolic process | 9.8485 | 4 | yes |
| GO:0051093 | negative regulation of developmental process | 9.8485 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 9.8485 | 4 | yes |
| GO:1901136 | carbohydrate derivative catabolic process | 9.8485 | 4 | yes |
| GO:1901292 | nucleoside phosphate catabolic process | 9.8485 | 5 | yes |
| GO:0006096 | glycolytic process | 9.0909 | 4 | yes |
| GO:0006195 | purine nucleotide catabolic process | 9.0909 | 6 | yes |
| GO:0009132 | nucleoside diphosphate metabolic process | 9.0909 | 5 | yes |
| GO:0009134 | nucleoside diphosphate catabolic process | 9.0909 | 6 | yes |
| GO:0009135 | purine nucleoside diphosphate metabolic process | 9.0909 | 6 | yes |
| GO:0009137 | purine nucleoside diphosphate catabolic process | 9.0909 | 7 | yes |
| GO:0009154 | purine ribonucleotide catabolic process | 9.0909 | 6 | yes |
| GO:0009179 | purine ribonucleoside diphosphate metabolic process | 9.0909 | 7 | yes |
| GO:0009181 | purine ribonucleoside diphosphate catabolic process | 9.0909 | 8 | yes |
| GO:0009185 | ribonucleoside diphosphate metabolic process | 9.0909 | 6 | yes |
| GO:0009191 | ribonucleoside diphosphate catabolic process | 9.0909 | 7 | yes |
| GO:0009261 | ribonucleotide catabolic process | 9.0909 | 5 | yes |
| GO:0016051 | carbohydrate biosynthetic process | 9.0909 | 4 | yes |
| GO:0019364 | pyridine nucleotide catabolic process | 9.0909 | 6 | yes |
| GO:0046031 | ADP metabolic process | 9.0909 | 7 | yes |
| GO:0046032 | ADP catabolic process | 9.0909 | 7 | yes |
| GO:0072523 | purine-containing compound catabolic process | 9.0909 | 5 | yes |
| GO:0072526 | pyridine-containing compound catabolic process | 9.0909 | 5 | yes |
| GO:0016310 | phosphorylation | 8.3333 | 5 | yes |
| GO:0019318 | hexose metabolic process | 8.3333 | 4 | yes |
| GO:0046364 | monosaccharide biosynthetic process | 8.3333 | 4 | yes |
| GO:0006006 | glucose metabolic process | 7.5758 | 5 | yes |
| GO:0006094 | gluconeogenesis | 6.8182 | 6 | yes |
| GO:0019319 | hexose biosynthetic process | 6.8182 | 5 | yes |
| GO:0019674 | NAD metabolic process | 6.8182 | 6 | yes |
| GO:0006734 | NADH metabolic process | 6.0606 | 7 | yes |
| GO:0030855 | epithelial cell differentiation | 6.0606 | 4 | yes |
| GO:0006007 | glucose catabolic process | 5.3030 | 6 | yes |
| GO:0006735 | NADH regeneration | 5.3030 | 8 | yes |
| GO:0019320 | hexose catabolic process | 5.3030 | 5 | yes |
| GO:0019677 | NAD catabolic process | 5.3030 | 7 | yes |
| GO:0046365 | monosaccharide catabolic process | 5.3030 | 4 | yes |
| GO:0061615 | glycolytic process through fructose-6-phosphate | 5.3030 | 5 | yes |
| GO:0061620 | glycolytic process through glucose-6-phosphate | 5.3030 | 6 | yes |
| GO:0061621 | canonical glycolysis | 5.3030 | 7 | yes |
| GO:0061718 | glucose catabolic process to pyruvate | 5.3030 | 7 | yes |
| GO:0051604 | protein maturation | 3.0303 | 4 | yes |
| GO:0016485 | protein processing | 2.2727 | 5 | yes |
| GO:0036293 | response to decreased oxygen levels | 2.2727 | 4 | yes |
| GO:0045765 | regulation of angiogenesis | 2.2727 | 5 | yes |
| GO:1901342 | regulation of vasculature development | 2.2727 | 5 | yes |
| GO:0016525 | negative regulation of angiogenesis | 1.5152 | 6 | yes |
| GO:0036294 | cellular response to decreased oxygen levels | 1.5152 | 5 | yes |
| GO:0071453 | cellular response to oxygen levels | 1.5152 | 4 | yes |
| GO:0071456 | cellular response to hypoxia | 1.5152 | 4 | yes |
| GO:1901343 | negative regulation of vasculature development | 1.5152 | 5 | yes |
| GO:2000181 | negative regulation of blood vessel morphogenesis | 1.5152 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MCM2_HUMAN | [view interactions] | Low throughput | no | no |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RFIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
| PK3C3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAKOR_HUMAN | [view interactions] | Low throughput | no | yes |
| NAA10_HUMAN | [view interactions] | Low throughput | no | yes |
| CDC7_HUMAN | [view interactions] | Low throughput | no | yes |
| CSK21_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TENA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| G3P_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STAT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| ELP3_HUMAN | [view interactions] | Low throughput | no | no |
| HDAC3_HUMAN | [view interactions] | Low throughput | no | yes |
| NEK7_HUMAN | [view interactions] | Low throughput | no | yes |
| PGAM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HS105_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCDH7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| KTNA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| ASB9_HUMAN | [view interactions] | High throughput | no | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| TGFR2_HUMAN | [view interactions] | High throughput | no | no |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| NHLC2_HUMAN | [view interactions] | High throughput | no | yes |
| TFE3_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| MRP6_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| EMC4_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| UCK1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AN32B_HUMAN | [view interactions] | High throughput | no | yes |
| CALR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STMN1_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANXA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| PTMS_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PGAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
| ATIF1_HUMAN | [view interactions] | High throughput | no | yes |
| YAF2_HUMAN | [view interactions] | High throughput | no | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| HMGN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBRS_HUMAN | [view interactions] | High throughput | no | no |
| PCGF3_HUMAN | [view interactions] | High throughput | no | yes |
| PCGF5_HUMAN | [view interactions] | High throughput | no | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP6_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSX2_HUMAN | [view interactions] | High throughput | no | no |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| FBX34_HUMAN | [view interactions] | High throughput | no | no |
| TET5C_HUMAN | [view interactions] | High throughput | no | yes |
| FND3A_HUMAN | [view interactions] | High throughput | no | yes |
| TRI72_HUMAN | [view interactions] | High throughput | no | no |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| RN149_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| KIF15_HUMAN | [view interactions] | High throughput | no | no |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| SYCM_HUMAN | [view interactions] | High throughput | no | yes |
| COQ2_HUMAN | [view interactions] | High throughput | no | yes |
| COX16_HUMAN | [view interactions] | High throughput | no | no |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEO1_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| RT63_HUMAN | [view interactions] | High throughput | no | yes |
| RM10_HUMAN | [view interactions] | High throughput | no | yes |
| RM22_HUMAN | [view interactions] | High throughput | no | yes |
| RM33_HUMAN | [view interactions] | High throughput | no | yes |
| RM37_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| RT11_HUMAN | [view interactions] | High throughput | no | yes |
| RT21_HUMAN | [view interactions] | High throughput | no | no |
| RT30_HUMAN | [view interactions] | High throughput | no | yes |
| PAPD1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB1_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB2_HUMAN | [view interactions] | High throughput | no | yes |
| NTF2_HUMAN | [view interactions] | High throughput | no | yes |
| 6PGD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DMAC1_HUMAN | [view interactions] | High throughput | no | no |
| SKI8_HUMAN | [view interactions] | High throughput | no | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| ITA2B_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBE3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK13_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FND3B_HUMAN | [view interactions] | High throughput | no | no |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBA5_HUMAN | [view interactions] | High throughput | no | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHLB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKG2_HUMAN | [view interactions] | High throughput | no | yes |
| HTSF1_HUMAN | [view interactions] | High throughput | no | yes |
| AAKG1_HUMAN | [view interactions] | High throughput | no | no |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| NRBF2_HUMAN | [view interactions] | High throughput | no | yes |
| SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| BOLA2_HUMAN | [view interactions] | High throughput | no | yes |
| FOXO3_HUMAN | [view interactions] | High throughput | no | yes |
| AK1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| ALDR_HUMAN | [view interactions] | High throughput | no | no |
| ATGA1_HUMAN | [view interactions] | High throughput | no | yes |
| AK1BA_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFIX_HUMAN | [view interactions] | High throughput | no | no |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFX5_HUMAN | [view interactions] | High throughput | no | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPA_HUMAN | [view interactions] | High throughput | no | no |
| ENOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CE162_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| LCA5_HUMAN | [view interactions] | High throughput | no | no |
| MTND_HUMAN | [view interactions] | High throughput | no | yes |
| PGK2_HUMAN | [view interactions] | High throughput | no | no |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| FUMH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHOC2_HUMAN | [view interactions] | High throughput | no | yes |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| CLC4G_HUMAN | [view interactions] | High throughput | no | no |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| PSB1_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| PYGL_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSB2_HUMAN | [view interactions] | High throughput | no | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| PPTC7_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHOP1_HUMAN | [view interactions] | High throughput | no | no |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| TAGL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| TAGL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYLK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COQ9_HUMAN | [view interactions] | High throughput | no | yes |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| G6PI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| RS17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| CSRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CK068_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX3_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| FBRL_HUMAN | [view interactions] | High throughput | no | yes |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| CLIC6_HUMAN | [view interactions] | High throughput | no | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TRAIP_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ARL6_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |