XPO2_HUMAN
Evidence for PS localization
Functions
Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in XPO2_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 40.5063 | 4 | no |
| GO:0017076 | purine nucleotide binding | 40.5063 | 5 | no |
| GO:0043168 | anion binding | 40.5063 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 39.2405 | 4 | no |
| GO:0043169 | cation binding | 39.2405 | 4 | no |
| GO:0046872 | metal ion binding | 39.2405 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 36.7089 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 27.8481 | 6 | no |
| GO:0019900 | kinase binding | 26.5823 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 26.5823 | 5 | no |
| GO:0019901 | protein kinase binding | 25.3165 | 5 | no |
| GO:0005524 | ATP binding | 24.0506 | 5 | no |
| GO:0003723 | RNA binding | 22.7848 | 4 | no |
| GO:0031267 | small GTPase binding | 6.3291 | 5 | yes |
| GO:0051020 | GTPase binding | 6.3291 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in XPO2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 55.6962 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 51.8987 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 49.3671 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.1013 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 44.3038 | 4 | no |
| GO:0010646 | regulation of cell communication | 44.3038 | 4 | no |
| GO:0009966 | regulation of signal transduction | 40.5063 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 39.2405 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 39.2405 | 5 | no |
| GO:0010468 | regulation of gene expression | 37.9747 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 37.9747 | 5 | no |
| GO:0008104 | protein localization | 34.1772 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 34.1772 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 34.1772 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 32.9114 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.9114 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 31.6456 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.3797 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 30.3797 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 30.3797 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.1139 | 5 | no |
| GO:0006996 | organelle organization | 29.1139 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.8481 | 5 | no |
| GO:0022607 | cellular component assembly | 27.8481 | 4 | no |
| GO:0023056 | positive regulation of signaling | 27.8481 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.5823 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 26.5823 | 5 | no |
| GO:0060341 | regulation of cellular localization | 26.5823 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.3165 | 4 | no |
| GO:0031399 | regulation of protein modification process | 25.3165 | 6 | no |
| GO:0032880 | regulation of protein localization | 25.3165 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 25.3165 | 5 | no |
| GO:0036211 | protein modification process | 24.0506 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 24.0506 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 24.0506 | 4 | no |
| GO:0043412 | macromolecule modification | 24.0506 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.0506 | 6 | no |
| GO:0051049 | regulation of transport | 24.0506 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.0506 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 21.5190 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.5190 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.5190 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.2532 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 20.2532 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 20.2532 | 6 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.2532 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.2532 | 7 | no |
| GO:0042325 | regulation of phosphorylation | 20.2532 | 7 | no |
| GO:1903829 | positive regulation of protein localization | 20.2532 | 5 | no |
| GO:0009968 | negative regulation of signal transduction | 20.2532 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.2532 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.2532 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 20.2532 | 5 | no |
| GO:0071702 | organic substance transport | 18.9873 | 4 | yes |
| GO:0033365 | protein localization to organelle | 17.7215 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 16.4557 | 4 | yes |
| GO:0015031 | protein transport | 15.1899 | 4 | yes |
| GO:0006886 | intracellular protein transport | 12.6582 | 4 | yes |
| GO:0006913 | nucleocytoplasmic transport | 10.1266 | 5 | yes |
| GO:0034504 | protein localization to nucleus | 10.1266 | 6 | yes |
| GO:0051169 | nuclear transport | 10.1266 | 4 | yes |
| GO:0006606 | protein import into nucleus | 7.5949 | 5 | yes |
| GO:0051170 | import into nucleus | 7.5949 | 6 | yes |
| GO:0072594 | establishment of protein localization to organelle | 7.5949 | 4 | yes |
| GO:0006611 | protein export from nucleus | 5.0633 | 5 | yes |
| GO:0051168 | nuclear export | 5.0633 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| IMA3_HUMAN | [view interactions] | Low throughput | no | yes |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| P53_HUMAN | [view interactions] | Low throughput | no | no |
| IMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 4ET_HUMAN | [view interactions] | Low throughput | no | yes |
| NRIP1_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BIRC2_HUMAN | [view interactions] | Low throughput | no | yes |
| IMA5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| B3GN2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATG10_HUMAN | [view interactions] | High throughput | no | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYDC_HUMAN | [view interactions] | High throughput | no | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN45A_HUMAN | [view interactions] | High throughput | no | yes |
| TXND5_HUMAN | [view interactions] | High throughput | no | yes |
| AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| UBP19_HUMAN | [view interactions] | High throughput | no | no |
| UBR1_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| UBXN1_HUMAN | [view interactions] | High throughput | no | no |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| NFAC2_HUMAN | [view interactions] | High throughput | no | yes |
| UBP1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CIA2B_HUMAN | [view interactions] | High throughput | no | yes |
| BCCIP_HUMAN | [view interactions] | High throughput | no | no |
| URM1_HUMAN | [view interactions] | High throughput | no | yes |
| KCRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| CHRD1_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRAGB_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCEA1_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GUAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSF3_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| KYNU_HUMAN | [view interactions] | High throughput | no | no |
| PTPRE_HUMAN | [view interactions] | High throughput | no | no |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| MVD1_HUMAN | [view interactions] | High throughput | no | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| PSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMIG1_HUMAN | [view interactions] | High throughput | no | no |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCLY_HUMAN | [view interactions] | High throughput | no | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| SPSY_HUMAN | [view interactions] | High throughput | no | no |
| RBM45_HUMAN | [view interactions] | High throughput | no | yes |
| TBCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| UBFD1_HUMAN | [view interactions] | High throughput | no | no |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACD1_HUMAN | [view interactions] | High throughput | no | no |
| MTAP_HUMAN | [view interactions] | High throughput | no | no |
| M4A4A_HUMAN | [view interactions] | High throughput | no | no |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| PGK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TN13B_HUMAN | [view interactions] | High throughput | no | no |
| PLAP_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| MTREX_HUMAN | [view interactions] | High throughput | no | yes |
| VAMP5_HUMAN | [view interactions] | High throughput | no | no |
| XPP1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| ST1C3_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ST1C4_HUMAN | [view interactions] | High throughput | no | no |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIPRL_HUMAN | [view interactions] | High throughput | no | yes |
| GRK6_HUMAN | [view interactions] | High throughput | no | yes |
| TPP2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| COQ8A_HUMAN | [view interactions] | High throughput | no | no |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| SG196_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAT_HUMAN | [view interactions] | High throughput | no | no |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZAP70_HUMAN | [view interactions] | High throughput | no | no |
| PSMD3_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| ANM3_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| NFIC_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC5_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| PSB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| PPCE_HUMAN | [view interactions] | High throughput | no | yes |
| TX101_HUMAN | [view interactions] | High throughput | no | no |
| TAF6_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNBP_HUMAN | [view interactions] | High throughput | no | no |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM62_HUMAN | [view interactions] | High throughput | no | yes |
| GT251_HUMAN | [view interactions] | High throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| SMYD3_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| R113A_HUMAN | [view interactions] | High throughput | no | yes |
| NEMO_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| TNR1B_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| STK4_HUMAN | [view interactions] | High throughput | no | yes |
| KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| AMFR_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| FBX25_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ASB16_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| TM171_HUMAN | [view interactions] | High throughput | no | yes |
| VSIG2_HUMAN | [view interactions] | High throughput | no | no |
| XRP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI18A_HUMAN | [view interactions] | High throughput | no | yes |
| PPME1_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| NKX21_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRN_HUMAN | [view interactions] | High throughput | no | yes |
| PACC1_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| CCND2_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| TPTE_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| RN181_HUMAN | [view interactions] | High throughput | no | no |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| R144A_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| CCND1_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| PPAP_HUMAN | [view interactions] | High throughput | no | no |
| DUS16_HUMAN | [view interactions] | High throughput | no | yes |
| DUS23_HUMAN | [view interactions] | High throughput | no | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRM_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRU_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| ARGAL_HUMAN | [view interactions] | High throughput | no | yes |
| DEP1B_HUMAN | [view interactions] | High throughput | no | yes |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| MALL_HUMAN | [view interactions] | High throughput | no | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR5_HUMAN | [view interactions] | High throughput | no | no |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPP3_HUMAN | [view interactions] | High throughput | no | no |
| GPR17_HUMAN | [view interactions] | High throughput | no | no |
| VIPR1_HUMAN | [view interactions] | High throughput | no | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| MAP7_HUMAN | [view interactions] | High throughput | no | yes |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| FPR1_HUMAN | [view interactions] | High throughput | no | no |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| GTR1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| OPALI_HUMAN | [view interactions] | High throughput | no | yes |
| TPST2_HUMAN | [view interactions] | High throughput | no | yes |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| CMTD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPR45_HUMAN | [view interactions] | High throughput | no | no |
| SYT6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AQP3_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| NUP50_HUMAN | [view interactions] | High throughput | no | yes |
| SRP54_HUMAN | [view interactions] | High throughput | no | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| ARMC5_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| HAPR1_HUMAN | [view interactions] | High throughput | no | yes |
| LOXL2_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD9_HUMAN | [view interactions] | High throughput | no | no |
| GBRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |