THIL_HUMAN
Evidence for PS localization
Functions
This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (PubMed, PubMed, PubMed). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (PubMed, PubMed, PubMed). The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA (PubMed). Thereby, it plays a major role in ketone body metabolism (PubMed, PubMed, PubMed, PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in THIL_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 34.2105 | 4 | yes |
| GO:0043168 | anion binding | 32.8947 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 31.5789 | 5 | yes |
| GO:0003723 | RNA binding | 30.2632 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 28.9474 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.3158 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.6842 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 21.0526 | 5 | yes |
| GO:0043169 | cation binding | 21.0526 | 4 | yes |
| GO:0046872 | metal ion binding | 21.0526 | 5 | yes |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | 5.2632 | 4 | yes |
| GO:0003985 | acetyl-CoA C-acetyltransferase activity | 3.9474 | 7 | yes |
| GO:0003988 | acetyl-CoA C-acyltransferase activity | 3.9474 | 6 | yes |
| GO:0016407 | acetyltransferase activity | 3.9474 | 5 | yes |
| GO:0016408 | C-acyltransferase activity | 3.9474 | 5 | yes |
| GO:0016453 | C-acetyltransferase activity | 3.9474 | 6 | yes |
| GO:0004772 | sterol O-acyltransferase activity | 2.6316 | 6 | yes |
| GO:0008374 | O-acyltransferase activity | 2.6316 | 5 | yes |
| GO:0030955 | potassium ion binding | 2.6316 | 7 | yes |
| GO:0031420 | alkali metal ion binding | 2.6316 | 6 | yes |
| GO:0034736 | cholesterol O-acyltransferase activity | 2.6316 | 7 | yes |
| GO:0120225 | coenzyme A binding | 2.6316 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in THIL_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 48.6842 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 47.3684 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 44.7368 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 42.1053 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 38.1579 | 4 | no |
| GO:0010646 | regulation of cell communication | 38.1579 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.8421 | 4 | no |
| GO:0022607 | cellular component assembly | 36.8421 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 35.5263 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.2105 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 34.2105 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 34.2105 | 4 | no |
| GO:0006996 | organelle organization | 32.8947 | 4 | no |
| GO:0010468 | regulation of gene expression | 32.8947 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 32.8947 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 32.8947 | 5 | no |
| GO:0008104 | protein localization | 30.2632 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 28.9474 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 28.9474 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.9474 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.6316 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.3158 | 5 | no |
| GO:0043933 | protein-containing complex organization | 26.3158 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 26.3158 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.3158 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 26.3158 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.3158 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 25.0000 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.0000 | 4 | no |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 23.6842 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.6842 | 4 | no |
| GO:0009894 | regulation of catabolic process | 23.6842 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 23.6842 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.6842 | 5 | no |
| GO:0071705 | nitrogen compound transport | 23.6842 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 22.3684 | 5 | no |
| GO:0043412 | macromolecule modification | 22.3684 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.3684 | 6 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.3684 | 5 | no |
| GO:0031399 | regulation of protein modification process | 21.0526 | 6 | no |
| GO:0036211 | protein modification process | 21.0526 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 21.0526 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.0526 | 7 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.0526 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.0526 | 6 | no |
| GO:0051049 | regulation of transport | 21.0526 | 4 | no |
| GO:0019752 | carboxylic acid metabolic process | 18.4211 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 18.4211 | 4 | yes |
| GO:1901565 | organonitrogen compound catabolic process | 17.1053 | 4 | yes |
| GO:0006163 | purine nucleotide metabolic process | 15.7895 | 5 | yes |
| GO:0006753 | nucleoside phosphate metabolic process | 15.7895 | 4 | yes |
| GO:0009117 | nucleotide metabolic process | 15.7895 | 5 | yes |
| GO:0072521 | purine-containing compound metabolic process | 15.7895 | 4 | yes |
| GO:0032787 | monocarboxylic acid metabolic process | 13.1579 | 6 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 13.1579 | 4 | yes |
| GO:0009150 | purine ribonucleotide metabolic process | 11.8421 | 6 | yes |
| GO:0009259 | ribonucleotide metabolic process | 11.8421 | 5 | yes |
| GO:0014070 | response to organic cyclic compound | 11.8421 | 4 | yes |
| GO:0019693 | ribose phosphate metabolic process | 11.8421 | 4 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 11.8421 | 4 | yes |
| GO:0016042 | lipid catabolic process | 10.5263 | 4 | yes |
| GO:0016054 | organic acid catabolic process | 10.5263 | 4 | yes |
| GO:0046395 | carboxylic acid catabolic process | 10.5263 | 5 | yes |
| GO:0006631 | fatty acid metabolic process | 9.2105 | 4 | yes |
| GO:0009063 | amino acid catabolic process | 9.2105 | 4 | yes |
| GO:0030258 | lipid modification | 9.2105 | 4 | yes |
| GO:0006635 | fatty acid beta-oxidation | 7.8947 | 6 | yes |
| GO:0009062 | fatty acid catabolic process | 7.8947 | 5 | yes |
| GO:0019395 | fatty acid oxidation | 7.8947 | 5 | yes |
| GO:0034440 | lipid oxidation | 7.8947 | 5 | yes |
| GO:0044242 | cellular lipid catabolic process | 7.8947 | 4 | yes |
| GO:0072329 | monocarboxylic acid catabolic process | 7.8947 | 6 | yes |
| GO:0090407 | organophosphate biosynthetic process | 7.8947 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 7.8947 | 4 | yes |
| GO:0006084 | acetyl-CoA metabolic process | 6.5789 | 4 | yes |
| GO:0006164 | purine nucleotide biosynthetic process | 6.5789 | 6 | yes |
| GO:0009081 | branched-chain amino acid metabolic process | 6.5789 | 4 | yes |
| GO:0009083 | branched-chain amino acid catabolic process | 6.5789 | 5 | yes |
| GO:0009152 | purine ribonucleotide biosynthetic process | 6.5789 | 7 | yes |
| GO:0009165 | nucleotide biosynthetic process | 6.5789 | 6 | yes |
| GO:0009260 | ribonucleotide biosynthetic process | 6.5789 | 6 | yes |
| GO:0033865 | nucleoside bisphosphate metabolic process | 6.5789 | 5 | yes |
| GO:0033875 | ribonucleoside bisphosphate metabolic process | 6.5789 | 6 | yes |
| GO:0034032 | purine nucleoside bisphosphate metabolic process | 6.5789 | 5 | yes |
| GO:0046390 | ribose phosphate biosynthetic process | 6.5789 | 5 | yes |
| GO:0072522 | purine-containing compound biosynthetic process | 6.5789 | 5 | yes |
| GO:1901137 | carbohydrate derivative biosynthetic process | 6.5789 | 4 | yes |
| GO:1901293 | nucleoside phosphate biosynthetic process | 6.5789 | 5 | yes |
| GO:1901361 | organic cyclic compound catabolic process | 6.5789 | 4 | yes |
| GO:1901605 | alpha-amino acid metabolic process | 6.5789 | 4 | yes |
| GO:1901606 | alpha-amino acid catabolic process | 6.5789 | 5 | yes |
| GO:0006085 | acetyl-CoA biosynthetic process | 5.2632 | 5 | yes |
| GO:0008610 | lipid biosynthetic process | 5.2632 | 4 | yes |
| GO:0033866 | nucleoside bisphosphate biosynthetic process | 5.2632 | 6 | yes |
| GO:0034030 | ribonucleoside bisphosphate biosynthetic process | 5.2632 | 7 | yes |
| GO:0034033 | purine nucleoside bisphosphate biosynthetic process | 5.2632 | 6 | yes |
| GO:0034655 | nucleobase-containing compound catabolic process | 5.2632 | 4 | yes |
| GO:0035384 | thioester biosynthetic process | 5.2632 | 4 | yes |
| GO:0044272 | sulfur compound biosynthetic process | 5.2632 | 4 | yes |
| GO:0048732 | gland development | 5.2632 | 4 | yes |
| GO:0071616 | acyl-CoA biosynthetic process | 5.2632 | 4 | yes |
| GO:0001889 | liver development | 3.9474 | 5 | yes |
| GO:0006549 | isoleucine metabolic process | 3.9474 | 5 | yes |
| GO:0006550 | isoleucine catabolic process | 3.9474 | 6 | yes |
| GO:0009166 | nucleotide catabolic process | 3.9474 | 6 | yes |
| GO:0046434 | organophosphate catabolic process | 3.9474 | 4 | yes |
| GO:1901292 | nucleoside phosphate catabolic process | 3.9474 | 5 | yes |
| GO:0006195 | purine nucleotide catabolic process | 2.6316 | 6 | yes |
| GO:0009154 | purine ribonucleotide catabolic process | 2.6316 | 6 | yes |
| GO:0009261 | ribonucleotide catabolic process | 2.6316 | 5 | yes |
| GO:0015936 | coenzyme A metabolic process | 2.6316 | 6 | yes |
| GO:0015937 | coenzyme A biosynthetic process | 2.6316 | 7 | yes |
| GO:0033869 | nucleoside bisphosphate catabolic process | 2.6316 | 6 | yes |
| GO:0034031 | ribonucleoside bisphosphate catabolic process | 2.6316 | 7 | yes |
| GO:0034034 | purine nucleoside bisphosphate catabolic process | 2.6316 | 6 | yes |
| GO:0035337 | fatty-acyl-CoA metabolic process | 2.6316 | 4 | yes |
| GO:0044273 | sulfur compound catabolic process | 2.6316 | 4 | yes |
| GO:0046356 | acetyl-CoA catabolic process | 2.6316 | 5 | yes |
| GO:0046949 | fatty-acyl-CoA biosynthetic process | 2.6316 | 5 | yes |
| GO:0046952 | ketone body catabolic process | 2.6316 | 4 | yes |
| GO:0060429 | epithelium development | 2.6316 | 4 | yes |
| GO:0060612 | adipose tissue development | 2.6316 | 5 | yes |
| GO:0061326 | renal tubule development | 2.6316 | 4 | yes |
| GO:0061448 | connective tissue development | 2.6316 | 4 | yes |
| GO:0072009 | nephron epithelium development | 2.6316 | 6 | yes |
| GO:0072019 | proximal convoluted tubule development | 2.6316 | 6 | yes |
| GO:0072073 | kidney epithelium development | 2.6316 | 5 | yes |
| GO:0072080 | nephron tubule development | 2.6316 | 5 | yes |
| GO:0072170 | metanephric tubule development | 2.6316 | 4 | yes |
| GO:0072207 | metanephric epithelium development | 2.6316 | 6 | yes |
| GO:0072229 | metanephric proximal convoluted tubule development | 2.6316 | 6 | yes |
| GO:0072234 | metanephric nephron tubule development | 2.6316 | 5 | yes |
| GO:0072243 | metanephric nephron epithelium development | 2.6316 | 7 | yes |
| GO:0072523 | purine-containing compound catabolic process | 2.6316 | 5 | yes |
| GO:1901136 | carbohydrate derivative catabolic process | 2.6316 | 4 | yes |
| GO:1901568 | fatty acid derivative metabolic process | 2.6316 | 4 | yes |
| GO:1901569 | fatty acid derivative catabolic process | 2.6316 | 5 | yes |
| GO:1901570 | fatty acid derivative biosynthetic process | 2.6316 | 5 | yes |
| GO:1902224 | ketone body metabolic process | 2.6316 | 4 | yes |
| GO:1902858 | propionyl-CoA metabolic process | 2.6316 | 5 | yes |
| GO:1902860 | propionyl-CoA biosynthetic process | 2.6316 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ODPA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PEX7_HUMAN | [view interactions] | Low throughput | no | yes |
| PDP1_HUMAN | [view interactions] | Low throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GCSP_HUMAN | [view interactions] | Low throughput | no | yes |
| THIL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SAFB1_HUMAN | [view interactions] | High throughput | no | yes |
| TOM7_HUMAN | [view interactions] | High throughput | no | no |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTF2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| TBB1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP2L_HUMAN | [view interactions] | High throughput | no | yes |
| ABCB7_HUMAN | [view interactions] | High throughput | no | yes |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERCC1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTBP1_HUMAN | [view interactions] | High throughput | no | no |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UD3A2_HUMAN | [view interactions] | High throughput | no | no |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| CRIP1_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUS3L_HUMAN | [view interactions] | High throughput | no | yes |
| ERCC2_HUMAN | [view interactions] | High throughput | no | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFXN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| COF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIT2_HUMAN | [view interactions] | High throughput | no | yes |
| KAD2_HUMAN | [view interactions] | High throughput | no | no |
| CH10_HUMAN | [view interactions] | High throughput | no | yes |
| IDHP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX17_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MRM1_HUMAN | [view interactions] | High throughput | no | no |
| GRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| AUHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTRFR_HUMAN | [view interactions] | High throughput | no | yes |
| CQ080_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAL3A_HUMAN | [view interactions] | High throughput | no | yes |
| GAL3B_HUMAN | [view interactions] | High throughput | no | no |
| MRES1_HUMAN | [view interactions] | High throughput | no | yes |
| CH082_HUMAN | [view interactions] | High throughput | no | yes |
| MCUR1_HUMAN | [view interactions] | High throughput | no | no |
| CC90B_HUMAN | [view interactions] | High throughput | no | yes |
| QOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD2_HUMAN | [view interactions] | High throughput | no | no |
| FAKD5_HUMAN | [view interactions] | High throughput | no | yes |
| EFGM_HUMAN | [view interactions] | High throughput | no | yes |
| HINT2_HUMAN | [view interactions] | High throughput | no | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCUB_HUMAN | [view interactions] | High throughput | no | no |
| MET15_HUMAN | [view interactions] | High throughput | no | no |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |
| RM11_HUMAN | [view interactions] | High throughput | no | yes |
| RT12_HUMAN | [view interactions] | High throughput | no | yes |
| RT26_HUMAN | [view interactions] | High throughput | no | yes |
| RRFM_HUMAN | [view interactions] | High throughput | no | yes |
| MTG2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2M_HUMAN | [view interactions] | High throughput | no | yes |
| IF3M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1M_HUMAN | [view interactions] | High throughput | no | yes |
| RF1ML_HUMAN | [view interactions] | High throughput | no | yes |
| OTC_HUMAN | [view interactions] | High throughput | no | no |
| MPPA_HUMAN | [view interactions] | High throughput | no | yes |
| MPPB_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD3_HUMAN | [view interactions] | High throughput | no | yes |
| RUSD4_HUMAN | [view interactions] | High throughput | no | yes |
| SLIRP_HUMAN | [view interactions] | High throughput | no | yes |
| TACO1_HUMAN | [view interactions] | High throughput | no | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMM70_HUMAN | [view interactions] | High throughput | no | yes |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| EFTS_HUMAN | [view interactions] | High throughput | no | no |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VWA8_HUMAN | [view interactions] | High throughput | no | yes |
| RCC1L_HUMAN | [view interactions] | High throughput | no | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| CLPP_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| SYAM_HUMAN | [view interactions] | High throughput | no | yes |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| NUP35_HUMAN | [view interactions] | High throughput | no | yes |
| ETFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| AGT1_HUMAN | [view interactions] | High throughput | no | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR4_HUMAN | [view interactions] | High throughput | no | yes |
| THIC_HUMAN | [view interactions] | High throughput | no | yes |
| MTA70_HUMAN | [view interactions] | High throughput | no | no |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| RHG24_HUMAN | [view interactions] | High throughput | no | yes |
| RHG44_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIM26_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LMTK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| EIF1B_HUMAN | [view interactions] | High throughput | no | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| SOMA_HUMAN | [view interactions] | High throughput | no | no |
| 3MG_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| ANGI_HUMAN | [view interactions] | High throughput | no | no |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAKD3_HUMAN | [view interactions] | High throughput | no | yes |
| AKIP_HUMAN | [view interactions] | High throughput | no | yes |
| CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDK1_HUMAN | [view interactions] | High throughput | no | yes |
| TR61B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| RAD21_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| CHIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| TIA1_HUMAN | [view interactions] | High throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COMP_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| RHG30_HUMAN | [view interactions] | High throughput | no | no |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGG_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| DLP1_HUMAN | [view interactions] | High throughput | no | no |
| ARK72_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| HEAT3_HUMAN | [view interactions] | High throughput | no | yes |
| PSB10_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| UBP48_HUMAN | [view interactions] | High throughput | no | yes |
| TET5C_HUMAN | [view interactions] | High throughput | no | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| GOLI_HUMAN | [view interactions] | High throughput | no | yes |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| TOPB1_HUMAN | [view interactions] | High throughput | no | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GCN1_HUMAN | [view interactions] | High throughput | no | yes |
| SYMC_HUMAN | [view interactions] | High throughput | no | yes |
| TMM65_HUMAN | [view interactions] | High throughput | no | no |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXM1_HUMAN | [view interactions] | High throughput | no | yes |
| QCR7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM44_HUMAN | [view interactions] | High throughput | no | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |