CYC_HUMAN
Evidence for PS localization
Functions
Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CYC_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 34.2342 | 4 | yes |
| GO:0020037 | heme binding | 4.5045 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CYC_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 45.9459 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 45.9459 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 45.9459 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.0450 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 44.1441 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 41.4414 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 41.4414 | 4 | no |
| GO:0010646 | regulation of cell communication | 39.6396 | 4 | no |
| GO:0009966 | regulation of signal transduction | 36.0360 | 4 | no |
| GO:0010468 | regulation of gene expression | 36.0360 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.2342 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 34.2342 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 34.2342 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 33.3333 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0010941 | regulation of cell death | 32.4324 | 4 | no |
| GO:0015980 | energy derivation by oxidation of organic compounds | 31.5315 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 31.5315 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 30.6306 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 30.6306 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.7297 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.7297 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 29.7297 | 6 | no |
| GO:0045333 | cellular respiration | 27.0270 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 27.0270 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.0270 | 4 | no |
| GO:0006996 | organelle organization | 27.0270 | 4 | no |
| GO:0043933 | protein-containing complex organization | 27.0270 | 4 | no |
| GO:0009060 | aerobic respiration | 26.1261 | 6 | yes |
| GO:0022900 | electron transport chain | 26.1261 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 26.1261 | 4 | no |
| GO:0022607 | cellular component assembly | 26.1261 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 26.1261 | 5 | no |
| GO:0023056 | positive regulation of signaling | 26.1261 | 4 | no |
| GO:0022904 | respiratory electron transport chain | 25.2252 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 25.2252 | 5 | no |
| GO:0051049 | regulation of transport | 25.2252 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.3243 | 6 | yes |
| GO:0036211 | protein modification process | 24.3243 | 4 | no |
| GO:0043412 | macromolecule modification | 24.3243 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.4234 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 23.4234 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 23.4234 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.4234 | 6 | no |
| GO:0071310 | cellular response to organic substance | 23.4234 | 4 | no |
| GO:0019646 | aerobic electron transport chain | 22.5225 | 6 | yes |
| GO:0043085 | positive regulation of catalytic activity | 22.5225 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 22.5225 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.5225 | 4 | no |
| GO:0060548 | negative regulation of cell death | 22.5225 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 22.5225 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 22.5225 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.6216 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 21.6216 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.6216 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 21.6216 | 5 | no |
| GO:0060341 | regulation of cellular localization | 21.6216 | 4 | no |
| GO:0031399 | regulation of protein modification process | 20.7207 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.7207 | 6 | no |
| GO:0009894 | regulation of catabolic process | 20.7207 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 18.0180 | 4 | yes |
| GO:0030162 | regulation of proteolysis | 14.4144 | 6 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 14.4144 | 5 | yes |
| GO:0006915 | apoptotic process | 13.5135 | 4 | yes |
| GO:0052547 | regulation of peptidase activity | 13.5135 | 5 | yes |
| GO:0052548 | regulation of endopeptidase activity | 12.6126 | 6 | yes |
| GO:0045862 | positive regulation of proteolysis | 11.7117 | 7 | yes |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 11.7117 | 7 | yes |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 10.8108 | 8 | yes |
| GO:0010952 | positive regulation of peptidase activity | 9.9099 | 6 | yes |
| GO:0010950 | positive regulation of endopeptidase activity | 9.0090 | 7 | yes |
| GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 9.0090 | 8 | yes |
| GO:0006508 | proteolysis | 8.1081 | 4 | yes |
| GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 8.1081 | 9 | yes |
| GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen | 7.2072 | 7 | yes |
| GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 6.3063 | 10 | yes |
| GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c | 5.4054 | 7 | yes |
| GO:0016485 | protein processing | 2.7027 | 5 | yes |
| GO:0031638 | zymogen activation | 2.7027 | 6 | yes |
| GO:0051604 | protein maturation | 2.7027 | 4 | yes |
| GO:0097202 | activation of cysteine-type endopeptidase activity | 2.7027 | 7 | yes |
| GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | 1.8018 | 11 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in CYC_HUMAN |
|---|---|---|---|---|
| DOID:1289 | neurodegenerative disease | 2.7027 | 4 | no |
| DOID:331 | central nervous system disease | 2.7027 | 3 | no |
| DOID:0050686 | organ system cancer | 1.8018 | 3 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 1.8018 | 6 | no |
| DOID:440 | neuromuscular disease | 1.8018 | 5 | no |
| DOID:574 | peripheral nervous system disease | 1.8018 | 3 | no |
| DOID:870 | neuropathy | 1.8018 | 4 | no |
| DOID:0050890 | synucleinopathy | 1.8018 | 5 | no |
| DOID:0060894 | early-onset Parkinsons disease | 1.8018 | 7 | no |
| DOID:14330 | Parkinsons disease | 1.8018 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| APAF_HUMAN | [view interactions] | Low throughput | no | no |
| R144B_HUMAN | [view interactions] | Low throughput | no | yes |
| SPNS1_HUMAN | [view interactions] | Low throughput | no | yes |
| NCPR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CISD2_HUMAN | [view interactions] | Low throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | Low throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CUL9_HUMAN | [view interactions] | Low throughput | no | no |
| AAPK1_HUMAN | [view interactions] | Low throughput | no | no |
| CYC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COX42_HUMAN | [view interactions] | Low throughput | no | no |
| CYB5_HUMAN | [view interactions] | Low throughput | no | no |
| QCR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NDOR1_HUMAN | [view interactions] | Low throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAX_HUMAN | [view interactions] | Low throughput | no | yes |
| CBPE_HUMAN | [view interactions] | Low throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| A2GL_HUMAN | [view interactions] | High throughput | no | no |
| SUCHY_HUMAN | [view interactions] | High throughput | no | yes |
| FMC1_HUMAN | [view interactions] | High throughput | no | no |
| COQ7_HUMAN | [view interactions] | High throughput | no | yes |
| OPA3_HUMAN | [view interactions] | High throughput | no | yes |
| PTPM1_HUMAN | [view interactions] | High throughput | no | yes |
| COQ6_HUMAN | [view interactions] | High throughput | no | yes |
| SPT20_HUMAN | [view interactions] | High throughput | no | yes |
| COQ8B_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCRIL_HUMAN | [view interactions] | High throughput | no | no |
| MED4_HUMAN | [view interactions] | High throughput | no | yes |
| MED23_HUMAN | [view interactions] | High throughput | no | no |
| MED20_HUMAN | [view interactions] | High throughput | no | no |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRM7_HUMAN | [view interactions] | High throughput | no | yes |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |
| PINX1_HUMAN | [view interactions] | High throughput | no | yes |
| TR10D_HUMAN | [view interactions] | High throughput | no | no |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSTK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOMA_HUMAN | [view interactions] | High throughput | no | no |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| IKKE_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| HLAB_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CBPC1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C40_HUMAN | [view interactions] | High throughput | no | no |
| FAM9A_HUMAN | [view interactions] | High throughput | no | no |
| LONF2_HUMAN | [view interactions] | High throughput | no | yes |
| ASCL4_HUMAN | [view interactions] | High throughput | no | no |
| LRC56_HUMAN | [view interactions] | High throughput | no | no |
| CC036_HUMAN | [view interactions] | High throughput | no | no |
| KCD17_HUMAN | [view interactions] | High throughput | no | yes |
| PHF23_HUMAN | [view interactions] | High throughput | no | yes |
| COA7_HUMAN | [view interactions] | High throughput | no | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3F_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT14_HUMAN | [view interactions] | High throughput | no | yes |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RUAS1_HUMAN | [view interactions] | High throughput | no | no |
| FX4L6_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| CASP9_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| LACTB_HUMAN | [view interactions] | High throughput | no | yes |
| OMA1_HUMAN | [view interactions] | High throughput | no | no |
| PARL_HUMAN | [view interactions] | High throughput | no | yes |
| YMEL1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| RD23B_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CQ10B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC13_HUMAN | [view interactions] | High throughput | no | yes |
| MIX23_HUMAN | [view interactions] | High throughput | no | yes |
| PPA6_HUMAN | [view interactions] | High throughput | no | no |
| TRUB2_HUMAN | [view interactions] | High throughput | no | yes |
| ETFR1_HUMAN | [view interactions] | High throughput | no | no |
| NDKM_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| ARHG4_HUMAN | [view interactions] | High throughput | no | yes |
| GMIP_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| GDIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCA_HUMAN | [view interactions] | High throughput | no | yes |
| DOPD_HUMAN | [view interactions] | High throughput | no | yes |
| CYTB_HUMAN | [view interactions] | High throughput | no | no |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SELS_HUMAN | [view interactions] | High throughput | no | yes |
| PHF3_HUMAN | [view interactions] | High throughput | no | yes |
| SFSWA_HUMAN | [view interactions] | High throughput | no | yes |
| RSRC1_HUMAN | [view interactions] | High throughput | no | yes |
| PR38B_HUMAN | [view interactions] | High throughput | no | no |
| UBP36_HUMAN | [view interactions] | High throughput | no | yes |
| ESF1_HUMAN | [view interactions] | High throughput | no | yes |
| DCNL5_HUMAN | [view interactions] | High throughput | no | yes |
| CD11B_HUMAN | [view interactions] | High throughput | no | yes |
| UBP4_HUMAN | [view interactions] | High throughput | no | no |
| FANCB_HUMAN | [view interactions] | High throughput | no | no |
| RBM27_HUMAN | [view interactions] | High throughput | no | yes |
| SUGP1_HUMAN | [view interactions] | High throughput | no | yes |
| DIDO1_HUMAN | [view interactions] | High throughput | no | yes |
| AL1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| RP9_HUMAN | [view interactions] | High throughput | no | yes |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| ZGPAT_HUMAN | [view interactions] | High throughput | no | no |
| SIR1_HUMAN | [view interactions] | High throughput | no | yes |
| PRP16_HUMAN | [view interactions] | High throughput | no | yes |
| FANCL_HUMAN | [view interactions] | High throughput | no | yes |
| RBL2_HUMAN | [view interactions] | High throughput | no | yes |
| CCHL_HUMAN | [view interactions] | High throughput | no | yes |
| HABP4_HUMAN | [view interactions] | High throughput | no | yes |
| FP100_HUMAN | [view interactions] | High throughput | no | yes |
| DDX46_HUMAN | [view interactions] | High throughput | no | yes |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| RBM33_HUMAN | [view interactions] | High throughput | no | yes |
| SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBL1_HUMAN | [view interactions] | High throughput | no | yes |
| CWC25_HUMAN | [view interactions] | High throughput | no | yes |
| AL1A3_HUMAN | [view interactions] | High throughput | no | yes |
| CDK12_HUMAN | [view interactions] | High throughput | no | yes |
| ELOA1_HUMAN | [view interactions] | High throughput | no | yes |
| UTP11_HUMAN | [view interactions] | High throughput | no | yes |
| SNR27_HUMAN | [view interactions] | High throughput | no | yes |
| RB15B_HUMAN | [view interactions] | High throughput | no | yes |
| RRP36_HUMAN | [view interactions] | High throughput | no | yes |
| ZC3H4_HUMAN | [view interactions] | High throughput | no | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RSRC2_HUMAN | [view interactions] | High throughput | no | yes |
| ZG16B_HUMAN | [view interactions] | High throughput | no | no |
| ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCNA2_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| YTDC1_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ARL2_HUMAN | [view interactions] | High throughput | no | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPD1L_HUMAN | [view interactions] | High throughput | no | no |
| UCRI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLRX2_HUMAN | [view interactions] | High throughput | no | yes |
| IMPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMPA2_HUMAN | [view interactions] | High throughput | no | no |
| NLE1_HUMAN | [view interactions] | High throughput | no | yes |
| HCDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT5L2_HUMAN | [view interactions] | High throughput | no | no |
| ATP5L_HUMAN | [view interactions] | High throughput | no | yes |
| COX5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
| ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CISY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDHM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA3_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACPM_HUMAN | [view interactions] | High throughput | no | yes |
| NDUBA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUC2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUCR_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBX2_HUMAN | [view interactions] | High throughput | no | yes |
| SDHA_HUMAN | [view interactions] | High throughput | no | yes |
| SDHB_HUMAN | [view interactions] | High throughput | no | yes |
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR6L_HUMAN | [view interactions] | High throughput | no | yes |
| QCR6_HUMAN | [view interactions] | High throughput | no | yes |
| ATPMK_HUMAN | [view interactions] | High throughput | no | no |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUB5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| MIC26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFXN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| SHOC2_HUMAN | [view interactions] | Computational | no | yes |
| SURF1_HUMAN | [view interactions] | Computational | no | yes |
| TOX4_HUMAN | [view interactions] | Computational | no | yes |
| 2A5A_HUMAN | [view interactions] | Computational | no | yes |
| CASP8_HUMAN | [view interactions] | Computational | no | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPIF_HUMAN | [view interactions] | Computational | no | no |
| COX14_HUMAN | [view interactions] | Computational | no | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| C560_HUMAN | [view interactions] | Computational | no | no |
| 2ABA_HUMAN | [view interactions] | Computational | no | yes |
| ANXA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MYPT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX3_HUMAN | [view interactions] | Computational | no | yes |
| SORT_HUMAN | [view interactions] | Computational | no | yes |
| SCO2_HUMAN | [view interactions] | Computational | no | no |
| QCR7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SIR5_HUMAN | [view interactions] | Computational | no | yes |
| CASP3_HUMAN | [view interactions] | Computational | no | yes |
| CNEP1_HUMAN | [view interactions] | Computational | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CX7A1_HUMAN | [view interactions] | Computational | no | no |
| COX1_HUMAN | [view interactions] | Computational | no | yes |
| CYB_HUMAN | [view interactions] | Computational | no | yes |
| COX7R_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CANB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MAGD1_HUMAN | [view interactions] | Computational | no | no |
| PP4R4_HUMAN | [view interactions] | Computational | no | yes |
| TNR16_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BCL2_HUMAN | [view interactions] | Computational | no | no |
| AVEN_HUMAN | [view interactions] | Computational | no | yes |
| BAK_HUMAN | [view interactions] | Computational | no | no |
| PR15A_HUMAN | [view interactions] | Computational | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ALR_HUMAN | [view interactions] | Computational | no | yes |
| PTPA_HUMAN | [view interactions] | Computational | no | yes |
| XIAP_HUMAN | [view interactions] | Computational | no | yes |
| MPCP_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CARD8_HUMAN | [view interactions] | Computational | no | yes |
| ADX_HUMAN | [view interactions] | Computational | no | no |
| MYG_HUMAN | [view interactions] | Computational | no | no |
| TACO1_HUMAN | [view interactions] | Computational | no | yes |
| COX11_HUMAN | [view interactions] | Computational | no | yes |
| WDR82_HUMAN | [view interactions] | Computational | no | no |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GELS_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BID_HUMAN | [view interactions] | Computational | no | no |
| COX19_HUMAN | [view interactions] | Computational | no | yes |
| COX16_HUMAN | [view interactions] | Computational | no | no |
| COX15_HUMAN | [view interactions] | Computational | no | yes |
| NGB_HUMAN | [view interactions] | Computational | no | yes |
| HSPB3_HUMAN | [view interactions] | Computational | no | no |
| HSP74_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX7C_HUMAN | [view interactions] | Computational | no | yes |
| PP2AB_HUMAN | [view interactions] | Computational | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ALBU_HUMAN | [view interactions] | Computational | no | no |
| PP1G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| P53_HUMAN | [view interactions] | Computational | no | no |
| CASPA_HUMAN | [view interactions] | Computational | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| COX5B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ADT3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ERR1_HUMAN | [view interactions] | Computational | no | yes |
| NUCG_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CX6A1_HUMAN | [view interactions] | Computational | no | yes |
| COX2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SODM_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| QCR8_HUMAN | [view interactions] | Computational | no | yes |
| MCL1_HUMAN | [view interactions] | Computational | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PR15B_HUMAN | [view interactions] | Computational | no | no |
| PRGC2_HUMAN | [view interactions] | Computational | no | no |
| QCR10_HUMAN | [view interactions] | Computational | no | no |
| COX8A_HUMAN | [view interactions] | Computational | no | yes |
| COX20_HUMAN | [view interactions] | Computational | no | yes |
| MTHR_HUMAN | [view interactions] | Computational | no | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| BAD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MIA40_HUMAN | [view interactions] | Computational | no | yes |
| 2A5G_HUMAN | [view interactions] | Computational | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DHSD_HUMAN | [view interactions] | Computational | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NGF_HUMAN | [view interactions] | Computational | no | no |
| PP2BA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HTRA2_HUMAN | [view interactions] | Computational | no | yes |
| CH10_HUMAN | [view interactions] | Computational | no | yes |
| ADT4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NEPR1_HUMAN | [view interactions] | Computational | no | yes |
| SCO1_HUMAN | [view interactions] | Computational | no | yes |
| B2L11_HUMAN | [view interactions] | Computational | no | yes |
| NRF1_HUMAN | [view interactions] | Computational | no | yes |
| PP4R2_HUMAN | [view interactions] | Computational | no | yes |