GDIR1_HUMAN
Evidence for PS localization
Functions
Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI001421 | MOD_PKA_2 | MOD | 171 | 177 | - |
| ELMI001421 | MOD_PKA_2 | MOD | 171 | 177 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GDIR1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 39.1304 | 4 | no |
| GO:0000166 | nucleotide binding | 36.2319 | 4 | no |
| GO:0017076 | purine nucleotide binding | 36.2319 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 34.7826 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.7826 | 4 | no |
| GO:0003723 | RNA binding | 26.0870 | 4 | no |
| GO:0043169 | cation binding | 26.0870 | 4 | no |
| GO:0046872 | metal ion binding | 24.6377 | 5 | no |
| GO:0019900 | kinase binding | 21.7391 | 4 | no |
| GO:0030695 | GTPase regulator activity | 5.7971 | 4 | yes |
| GO:0005092 | GDP-dissociation inhibitor activity | 4.3478 | 5 | yes |
| GO:0005096 | GTPase activator activity | 4.3478 | 4 | yes |
| GO:0005094 | Rho GDP-dissociation inhibitor activity | 2.8986 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GDIR1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 69.5652 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.0725 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 55.0725 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 52.1739 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 52.1739 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 50.7246 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 50.7246 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 47.8261 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 47.8261 | 4 | no |
| GO:0010468 | regulation of gene expression | 46.3768 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 46.3768 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 46.3768 | 5 | no |
| GO:0010646 | regulation of cell communication | 44.9275 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 42.0290 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 42.0290 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 39.1304 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 39.1304 | 5 | no |
| GO:0051049 | regulation of transport | 36.2319 | 4 | yes |
| GO:0022607 | cellular component assembly | 36.2319 | 4 | no |
| GO:0060341 | regulation of cellular localization | 34.7826 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 34.7826 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 34.7826 | 5 | no |
| GO:0032880 | regulation of protein localization | 33.3333 | 5 | yes |
| GO:0008104 | protein localization | 33.3333 | 4 | no |
| GO:0033043 | regulation of organelle organization | 33.3333 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 33.3333 | 6 | no |
| GO:0006355 | regulation of DNA-templated transcription | 33.3333 | 7 | no |
| GO:0009891 | positive regulation of biosynthetic process | 33.3333 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 33.3333 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 31.8841 | 4 | yes |
| GO:0006996 | organelle organization | 31.8841 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 31.8841 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 31.8841 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 31.8841 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 30.4348 | 5 | yes |
| GO:0043412 | macromolecule modification | 30.4348 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.4348 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 28.9855 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 28.9855 | 4 | no |
| GO:0141124 | intracellular signaling cassette | 27.5362 | 4 | yes |
| GO:0036211 | protein modification process | 27.5362 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.5362 | 5 | no |
| GO:0023056 | positive regulation of signaling | 27.5362 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 27.5362 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 27.5362 | 6 | no |
| GO:2000145 | regulation of cell motility | 27.5362 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 26.0870 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.0870 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 26.0870 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 24.6377 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.6377 | 5 | no |
| GO:0043933 | protein-containing complex organization | 24.6377 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.6377 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.6377 | 4 | no |
| GO:0007264 | small GTPase-mediated signal transduction | 23.1884 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 23.1884 | 4 | yes |
| GO:0097435 | supramolecular fiber organization | 23.1884 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.1884 | 6 | no |
| GO:0030334 | regulation of cell migration | 23.1884 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 23.1884 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 23.1884 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.1884 | 5 | no |
| GO:0009894 | regulation of catabolic process | 23.1884 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.1884 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 23.1884 | 5 | no |
| GO:2000026 | regulation of multicellular organismal development | 23.1884 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.1884 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 21.7391 | 7 | no |
| GO:0071702 | organic substance transport | 21.7391 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 21.7391 | 8 | no |
| GO:0009968 | negative regulation of signal transduction | 21.7391 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 21.7391 | 5 | no |
| GO:0023057 | negative regulation of signaling | 21.7391 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.7391 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.7391 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 20.2899 | 7 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 20.2899 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 20.2899 | 4 | no |
| GO:0071705 | nitrogen compound transport | 20.2899 | 4 | no |
| GO:1903829 | positive regulation of protein localization | 20.2899 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.2899 | 4 | no |
| GO:0043069 | negative regulation of programmed cell death | 17.3913 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 15.9420 | 6 | yes |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 11.5942 | 6 | yes |
| GO:0007266 | Rho protein signal transduction | 10.1449 | 6 | yes |
| GO:0035023 | regulation of Rho protein signal transduction | 8.6957 | 7 | yes |
| GO:0071526 | semaphorin-plexin signaling pathway | 5.7971 | 4 | yes |
| GO:0098693 | regulation of synaptic vesicle cycle | 2.8986 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RADI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SET_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOG_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RHOC_HUMAN | [view interactions] | Low throughput | no | no |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GDIR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TNR19_HUMAN | [view interactions] | Low throughput | no | no |
| KANK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOH_HUMAN | [view interactions] | Low throughput | no | yes |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| RN128_HUMAN | [view interactions] | Low throughput | no | yes |
| XIAP_HUMAN | [view interactions] | Low throughput | no | yes |
| ESR1_HUMAN | [view interactions] | Low throughput | no | no |
| PSD10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
| WDR26_HUMAN | [view interactions] | Low throughput | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCTD5_HUMAN | [view interactions] | Low throughput | no | no |
| LIS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBC9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| KAT2B_HUMAN | [view interactions] | Low throughput | no | yes |
| SIR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| PLST_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| FA98B_HUMAN | [view interactions] | High throughput | no | yes |
| GDIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HINT1_HUMAN | [view interactions] | High throughput | no | yes |
| PEPL1_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFKAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO4_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| RAB25_HUMAN | [view interactions] | High throughput | no | no |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAK_HUMAN | [view interactions] | High throughput | no | no |
| CBX5_HUMAN | [view interactions] | High throughput | no | yes |
| 3HAO_HUMAN | [view interactions] | High throughput | no | no |
| HERP1_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| C560_HUMAN | [view interactions] | High throughput | no | no |
| KCNRG_HUMAN | [view interactions] | High throughput | no | no |
| TWF2_HUMAN | [view interactions] | High throughput | no | no |
| UB2L6_HUMAN | [view interactions] | High throughput | no | no |
| UB2R2_HUMAN | [view interactions] | High throughput | no | no |
| UFM1_HUMAN | [view interactions] | High throughput | no | yes |
| S10A9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| SH2D3_HUMAN | [view interactions] | High throughput | no | no |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| TINF2_HUMAN | [view interactions] | High throughput | no | no |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| PGS1_HUMAN | [view interactions] | High throughput | no | no |
| FES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| STA5B_HUMAN | [view interactions] | High throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYLK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYLK4_HUMAN | [view interactions] | High throughput | no | no |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EI2BA_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| ROAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2B1_HUMAN | [view interactions] | High throughput | no | no |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDN1B_HUMAN | [view interactions] | High throughput | no | yes |
| NED4L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| POTE1_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| STOM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EI2BD_HUMAN | [view interactions] | High throughput | no | yes |
| AN13A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2B_HUMAN | [view interactions] | High throughput | no | no |
| ACL6A_HUMAN | [view interactions] | High throughput | no | yes |
| TRI13_HUMAN | [view interactions] | High throughput | no | no |
| SUMO3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| GLUC_HUMAN | [view interactions] | High throughput | no | no |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MTPN_HUMAN | [view interactions] | High throughput | no | yes |
| MDHC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBCA_HUMAN | [view interactions] | High throughput | no | yes |
| DOPD_HUMAN | [view interactions] | High throughput | no | yes |
| CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYTB_HUMAN | [view interactions] | High throughput | no | no |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | High throughput | no | no |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| LEG8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MSX2_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| CSK_HUMAN | [view interactions] | High throughput | no | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASP7_HUMAN | [view interactions] | High throughput | no | no |
| BID_HUMAN | [view interactions] | High throughput | no | no |
| TR10B_HUMAN | [view interactions] | High throughput | no | no |
| FADD_HUMAN | [view interactions] | High throughput | no | yes |
| TNFL6_HUMAN | [view interactions] | High throughput | no | yes |
| MK08_HUMAN | [view interactions] | High throughput | no | yes |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CASPA_HUMAN | [view interactions] | High throughput | no | yes |
| CASP8_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6_HUMAN | [view interactions] | High throughput | no | no |
| TNR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PIR_HUMAN | [view interactions] | High throughput | no | no |
| ALDOA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ALDOC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| COMD4_HUMAN | [view interactions] | High throughput | no | no |
| COTL1_HUMAN | [view interactions] | High throughput | no | yes |
| DUT_HUMAN | [view interactions] | High throughput | no | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IMPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMPA2_HUMAN | [view interactions] | High throughput | no | no |
| INO1_HUMAN | [view interactions] | High throughput | no | no |