RAP1A_HUMAN
Evidence for PS localization
Functions
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RAP1A_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 42.5287 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 42.5287 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 40.2299 | 4 | yes |
| GO:0019900 | kinase binding | 29.8851 | 4 | no |
| GO:0019901 | protein kinase binding | 28.7356 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.2874 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.2874 | 5 | no |
| GO:0046872 | metal ion binding | 25.2874 | 4 | no |
| GO:0005524 | ATP binding | 22.9885 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 21.8391 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 21.8391 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 21.8391 | 6 | yes |
| GO:0003924 | GTPase activity | 20.6897 | 7 | yes |
| GO:0005525 | GTP binding | 17.2414 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 17.2414 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 17.2414 | 5 | yes |
| GO:0019003 | GDP binding | 14.9425 | 4 | yes |
| GO:0030695 | GTPase regulator activity | 14.9425 | 4 | yes |
| GO:0051020 | GTPase binding | 12.6437 | 4 | yes |
| GO:0031267 | small GTPase binding | 10.3448 | 5 | yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 6.8966 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RAP1A_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 65.5172 | 4 | yes |
| GO:0010646 | regulation of cell communication | 64.3678 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 56.3218 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 52.8736 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 51.7241 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.5747 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 50.5747 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 49.4253 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 48.2759 | 4 | yes |
| GO:0010468 | regulation of gene expression | 42.5287 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 41.3793 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 41.3793 | 5 | yes |
| GO:0022607 | cellular component assembly | 41.3793 | 4 | no |
| GO:0051049 | regulation of transport | 40.2299 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 37.9310 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 37.9310 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 37.9310 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 36.7816 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 36.7816 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 36.7816 | 4 | yes |
| GO:0008104 | protein localization | 36.7816 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 35.6322 | 4 | yes |
| GO:0006996 | organelle organization | 35.6322 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.4828 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 33.3333 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | yes |
| GO:0009967 | positive regulation of signal transduction | 32.1839 | 5 | yes |
| GO:0010243 | response to organonitrogen compound | 32.1839 | 4 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 31.0345 | 4 | yes |
| GO:0010941 | regulation of cell death | 31.0345 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.0345 | 5 | no |
| GO:0051336 | regulation of hydrolase activity | 29.8851 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 29.8851 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 29.8851 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 28.7356 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 28.7356 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 28.7356 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 28.7356 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 28.7356 | 5 | no |
| GO:0071702 | organic substance transport | 28.7356 | 4 | no |
| GO:0031399 | regulation of protein modification process | 27.5862 | 6 | yes |
| GO:0042325 | regulation of phosphorylation | 27.5862 | 7 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 27.5862 | 5 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 27.5862 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 27.5862 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.5862 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 27.5862 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 27.5862 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 27.5862 | 6 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 26.4368 | 6 | yes |
| GO:0042127 | regulation of cell population proliferation | 26.4368 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 26.4368 | 4 | no |
| GO:0071705 | nitrogen compound transport | 26.4368 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 26.4368 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 26.4368 | 4 | yes |
| GO:0043408 | regulation of MAPK cascade | 25.2874 | 6 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 25.2874 | 6 | no |
| GO:0036211 | protein modification process | 25.2874 | 4 | no |
| GO:0043412 | macromolecule modification | 25.2874 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 25.2874 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 25.2874 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.2874 | 4 | no |
| GO:2000145 | regulation of cell motility | 25.2874 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 25.2874 | 7 | yes |
| GO:0045597 | positive regulation of cell differentiation | 24.1379 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 24.1379 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 24.1379 | 4 | yes |
| GO:0071417 | cellular response to organonitrogen compound | 24.1379 | 4 | yes |
| GO:1901699 | cellular response to nitrogen compound | 24.1379 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 24.1379 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 24.1379 | 5 | yes |
| GO:0042327 | positive regulation of phosphorylation | 22.9885 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.9885 | 7 | yes |
| GO:0051338 | regulation of transferase activity | 22.9885 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 22.9885 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.9885 | 6 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.9885 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.9885 | 4 | no |
| GO:0033043 | regulation of organelle organization | 22.9885 | 5 | no |
| GO:0030334 | regulation of cell migration | 22.9885 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.9885 | 6 | yes |
| GO:0031401 | positive regulation of protein modification process | 21.8391 | 7 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 21.8391 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 21.8391 | 5 | no |
| GO:0015031 | protein transport | 21.8391 | 4 | no |
| GO:0030030 | cell projection organization | 21.8391 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 21.8391 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.6897 | 5 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 20.6897 | 4 | no |
| GO:0016310 | phosphorylation | 20.6897 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.6897 | 4 | no |
| GO:0060284 | regulation of cell development | 20.6897 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.6897 | 5 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 20.6897 | 8 | yes |
| GO:0014070 | response to organic cyclic compound | 20.6897 | 4 | yes |
| GO:0032880 | regulation of protein localization | 19.5402 | 5 | yes |
| GO:0043087 | regulation of GTPase activity | 19.5402 | 5 | yes |
| GO:0051347 | positive regulation of transferase activity | 19.5402 | 5 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 19.5402 | 4 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 18.3908 | 7 | yes |
| GO:0043549 | regulation of kinase activity | 18.3908 | 5 | yes |
| GO:0007264 | small GTPase mediated signal transduction | 18.3908 | 4 | yes |
| GO:0070848 | response to growth factor | 17.2414 | 4 | yes |
| GO:0051046 | regulation of secretion | 16.0920 | 5 | yes |
| GO:0071407 | cellular response to organic cyclic compound | 16.0920 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 14.9425 | 6 | yes |
| GO:0043547 | positive regulation of GTPase activity | 14.9425 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 14.9425 | 6 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 14.9425 | 5 | yes |
| GO:1903530 | regulation of secretion by cell | 14.9425 | 4 | yes |
| GO:0031346 | positive regulation of cell projection organization | 14.9425 | 6 | yes |
| GO:0007265 | Ras protein signal transduction | 13.7931 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 13.7931 | 7 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 12.6437 | 7 | yes |
| GO:0072657 | protein localization to membrane | 12.6437 | 4 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 10.3448 | 7 | yes |
| GO:0017157 | regulation of exocytosis | 10.3448 | 5 | yes |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 9.1954 | 8 | yes |
| GO:0072659 | protein localization to plasma membrane | 9.1954 | 5 | yes |
| GO:1901888 | regulation of cell junction assembly | 9.1954 | 5 | yes |
| GO:1990778 | protein localization to cell periphery | 9.1954 | 5 | yes |
| GO:0051051 | negative regulation of transport | 8.0460 | 4 | yes |
| GO:1905475 | regulation of protein localization to membrane | 6.8966 | 6 | yes |
| GO:1990090 | cellular response to nerve growth factor stimulus | 6.8966 | 4 | yes |
| GO:0010976 | positive regulation of neuron projection development | 6.8966 | 7 | yes |
| GO:0038179 | neurotrophin signaling pathway | 5.7471 | 4 | yes |
| GO:0046683 | response to organophosphorus | 5.7471 | 4 | yes |
| GO:0051048 | negative regulation of secretion | 5.7471 | 5 | yes |
| GO:0051588 | regulation of neurotransmitter transport | 5.7471 | 5 | yes |
| GO:1903531 | negative regulation of secretion by cell | 5.7471 | 5 | yes |
| GO:1904375 | regulation of protein localization to cell periphery | 5.7471 | 6 | yes |
| GO:0002064 | epithelial cell development | 5.7471 | 4 | yes |
| GO:0014074 | response to purine-containing compound | 5.7471 | 5 | yes |
| GO:0046928 | regulation of neurotransmitter secretion | 4.5977 | 4 | yes |
| GO:0051591 | response to cAMP | 4.5977 | 4 | yes |
| GO:1903305 | regulation of regulated secretory pathway | 4.5977 | 6 | yes |
| GO:0032486 | Rap protein signal transduction | 3.4483 | 6 | yes |
| GO:0045920 | negative regulation of exocytosis | 3.4483 | 6 | yes |
| GO:0061028 | establishment of endothelial barrier | 3.4483 | 6 | yes |
| GO:0071320 | cellular response to cAMP | 3.4483 | 5 | yes |
| GO:1902683 | regulation of receptor localization to synapse | 3.4483 | 4 | yes |
| GO:2000300 | regulation of synaptic vesicle exocytosis | 3.4483 | 5 | yes |
| GO:0001885 | endothelial cell development | 3.4483 | 5 | yes |
| GO:0038180 | nerve growth factor signaling pathway | 2.2989 | 5 | yes |
| GO:0046929 | negative regulation of neurotransmitter secretion | 2.2989 | 5 | yes |
| GO:0050805 | negative regulation of synaptic transmission | 2.2989 | 5 | yes |
| GO:0051589 | negative regulation of neurotransmitter transport | 2.2989 | 5 | yes |
| GO:1902473 | regulation of protein localization to synapse | 2.2989 | 6 | yes |
| GO:1903306 | negative regulation of regulated secretory pathway | 2.2989 | 7 | yes |
| GO:2000301 | negative regulation of synaptic vesicle exocytosis | 2.2989 | 6 | yes |
| GO:2001212 | regulation of vasculogenesis | 2.2989 | 5 | yes |
| GO:2001214 | positive regulation of vasculogenesis | 2.2989 | 6 | yes |
| GO:0007399 | nervous system development | 2.2989 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in RAP1A_HUMAN |
|---|---|---|---|---|
| DOID:0050686 | organ system cancer | 2.2989 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RGDSR_HUMAN | [view interactions] | Low throughput | no | no |
| RUN3A_HUMAN | [view interactions] | Low throughput | no | yes |
| RGS14_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BIN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BMX_HUMAN | [view interactions] | Low throughput | no | no |
| SMCA2_HUMAN | [view interactions] | Low throughput | no | yes |
| TR10C_HUMAN | [view interactions] | Low throughput | no | no |
| ELOA1_HUMAN | [view interactions] | Low throughput | no | yes |
| FADD_HUMAN | [view interactions] | Low throughput | no | yes |
| FAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| HDAC1_HUMAN | [view interactions] | Low throughput | no | no |
| HSP74_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GBRL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARHG1_HUMAN | [view interactions] | Low throughput | no | no |
| RPGF3_HUMAN | [view interactions] | Low throughput | no | yes |
| RPGF4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RPGF5_HUMAN | [view interactions] | Low throughput | no | yes |
| RPGP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RPGF6_HUMAN | [view interactions] | Low throughput | no | yes |
| AB1IP_HUMAN | [view interactions] | Low throughput | no | no |
| GNDS_HUMAN | [view interactions] | Low throughput | no | yes |
| RASF5_HUMAN | [view interactions] | Low throughput | no | yes |
| GDS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRAF_HUMAN | [view interactions] | Low throughput | no | yes |
| PRAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| RPGF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KRIT1_HUMAN | [view interactions] | Low throughput | no | no |
| PDE6D_HUMAN | [view interactions] | Low throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RPGF1_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR6_HUMAN | [view interactions] | Low throughput | no | no |
| AFAD_HUMAN | [view interactions] | Low throughput | no | yes |
| TSC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHEB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NTRK1_HUMAN | [view interactions] | Low throughput | no | yes |
| RADIL_HUMAN | [view interactions] | Low throughput | no | no |
| GBB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DGKI_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SIR1_HUMAN | [view interactions] | Low throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| REQU_HUMAN | [view interactions] | High throughput | no | yes |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| ANDR_HUMAN | [view interactions] | High throughput | no | no |
| RGL1_HUMAN | [view interactions] | High throughput | no | yes |
| DPOE3_HUMAN | [view interactions] | High throughput | no | yes |
| O2T10_HUMAN | [view interactions] | High throughput | no | no |
| PIGO_HUMAN | [view interactions] | High throughput | no | no |
| TMM31_HUMAN | [view interactions] | High throughput | no | no |
| INSC_HUMAN | [view interactions] | High throughput | no | yes |
| NK3R_HUMAN | [view interactions] | High throughput | no | no |
| HYPM_HUMAN | [view interactions] | High throughput | no | no |
| BORC8_HUMAN | [view interactions] | High throughput | no | yes |
| CC85A_HUMAN | [view interactions] | High throughput | no | yes |
| RL35A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFT22_HUMAN | [view interactions] | High throughput | no | yes |
| CD53_HUMAN | [view interactions] | High throughput | no | yes |
| AGRF3_HUMAN | [view interactions] | High throughput | no | no |
| CENPM_HUMAN | [view interactions] | High throughput | no | yes |
| SAAL1_HUMAN | [view interactions] | High throughput | no | yes |
| MAGA3_HUMAN | [view interactions] | High throughput | no | no |
| PCDA8_HUMAN | [view interactions] | High throughput | no | no |
| CACL1_HUMAN | [view interactions] | High throughput | no | no |
| GPC3_HUMAN | [view interactions] | High throughput | no | no |
| MSS4_HUMAN | [view interactions] | High throughput | no | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
| PP4R2_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC8_HUMAN | [view interactions] | High throughput | no | yes |
| NKG2F_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| PON2_HUMAN | [view interactions] | High throughput | no | yes |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD11B_HUMAN | [view interactions] | High throughput | no | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHM_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB8B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| TAXB1_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RM34_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPLX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAKD4_HUMAN | [view interactions] | High throughput | no | yes |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| HNRDL_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRM7_HUMAN | [view interactions] | High throughput | no | yes |
| VHL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| GRP4_HUMAN | [view interactions] | High throughput | no | no |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| PARL_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| OXDA_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS19_HUMAN | [view interactions] | High throughput | no | yes |
| DUS22_HUMAN | [view interactions] | High throughput | no | yes |
| DUS9_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| UB2R1_HUMAN | [view interactions] | High throughput | no | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KPCD2_HUMAN | [view interactions] | Computational | no | yes |
| KPCD3_HUMAN | [view interactions] | Computational | no | yes |
| TIAM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| SIPA1_HUMAN | [view interactions] | Computational | no | yes |
| PLCE1_HUMAN | [view interactions] | Computational | no | yes |
| FRS3_HUMAN | [view interactions] | Computational | no | no |
| RET_HUMAN | [view interactions] | Computational | no | yes |
| ITAM_HUMAN | [view interactions] | Computational | no | no |
| PTN1_HUMAN | [view interactions] | Computational | no | yes |
| MP2K6_HUMAN | [view interactions] | Computational | no | yes |
| GAB1_HUMAN | [view interactions] | Computational | no | yes |
| CRKL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PTN11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TRAF3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MET_HUMAN | [view interactions] | Computational | no | yes |
| SI1L1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DAB1_HUMAN | [view interactions] | Computational | no | yes |
| M3K2_HUMAN | [view interactions] | Computational | no | yes |
| VAV3_HUMAN | [view interactions] | Computational | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ITA4_HUMAN | [view interactions] | Computational | no | no |
| CTND1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CAH2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| FRS2_HUMAN | [view interactions] | Computational | no | no |
| TLN1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GAB2_HUMAN | [view interactions] | Computational | no | yes |
| JAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GRP3_HUMAN | [view interactions] | Computational | no | no |
| GDNF_HUMAN | [view interactions] | Computational | no | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GRP1_HUMAN | [view interactions] | Computational | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KPCZ_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RPGP2_HUMAN | [view interactions] | Computational | no | yes |
| RAP1B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| MK08_HUMAN | [view interactions] | Computational | no | yes |
| KAPCB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARAP3_HUMAN | [view interactions] | Computational | no | no |
| ITAL_HUMAN | [view interactions] | Computational | no | no |
| DOK4_HUMAN | [view interactions] | Computational | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PEBP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HGF_HUMAN | [view interactions] | Computational | no | yes |
| CBL_HUMAN | [view interactions] | Computational | no | yes |
| EPOR_HUMAN | [view interactions] | Computational | no | no |
| ARAP1_HUMAN | [view interactions] | Computational | no | yes |
| GFRA1_HUMAN | [view interactions] | Computational | no | no |
| DOCK4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SKAP1_HUMAN | [view interactions] | Computational | no | no |
| KPCD1_HUMAN | [view interactions] | Computational | no | yes |
| VAV_HUMAN | [view interactions] | Computational | no | no |
| ITB2_HUMAN | [view interactions] | Computational | no | no |
| KCC2B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KDIS_HUMAN | [view interactions] | Computational | no | yes |
| VAV2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ID1_HUMAN | [view interactions] | Computational | no | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EPO_HUMAN | [view interactions] | Computational | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KPCI_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KAPCG_HUMAN | [view interactions] | Computational | no | no |
| GRP2_HUMAN | [view interactions] | Computational | no | yes |
| SI1L2_HUMAN | [view interactions] | Computational | no | yes |
| LCP2_HUMAN | [view interactions] | Computational | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MK09_HUMAN | [view interactions] | Computational | no | yes |
| FARP2_HUMAN | [view interactions] | Computational | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MP2K3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |