RGS14_HUMAN
Evidence for PS localization
Functions
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RGS14_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 25.9887 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 25.9887 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.4237 | 4 | no |
| GO:0046872 | metal ion binding | 24.2938 | 4 | no |
| GO:0003779 | actin binding | 22.0339 | 4 | no |
| GO:0003723 | RNA binding | 20.3390 | 4 | no |
| GO:0016462 | pyrophosphatase activity | 17.5141 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 17.5141 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 17.5141 | 6 | yes |
| GO:0003924 | GTPase activity | 15.8192 | 7 | yes |
| GO:0019900 | kinase binding | 15.2542 | 4 | yes |
| GO:0019901 | protein kinase binding | 13.5593 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 7.9096 | 4 | yes |
| GO:0005096 | GTPase activator activity | 5.0847 | 4 | yes |
| GO:0015631 | tubulin binding | 3.3898 | 4 | yes |
| GO:0008017 | microtubule binding | 2.8249 | 5 | yes |
| GO:0030159 | signaling receptor complex adaptor activity | 2.8249 | 4 | yes |
| GO:0005092 | GDP-dissociation inhibitor activity | 1.1299 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RGS14_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 45.1977 | 4 | yes |
| GO:0006996 | organelle organization | 38.9831 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 38.4181 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 38.4181 | 4 | no |
| GO:0022607 | cellular component assembly | 34.4633 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.8983 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 28.8136 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 27.6836 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 26.5537 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 25.9887 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 25.4237 | 4 | yes |
| GO:0051049 | regulation of transport | 25.4237 | 4 | no |
| GO:0007010 | cytoskeleton organization | 23.7288 | 5 | yes |
| GO:0008104 | protein localization | 23.1638 | 4 | no |
| GO:0033043 | regulation of organelle organization | 21.4689 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 20.9040 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 19.7740 | 5 | yes |
| GO:0010468 | regulation of gene expression | 19.2090 | 5 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 18.0791 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 18.0791 | 4 | yes |
| GO:0043085 | positive regulation of catalytic activity | 15.8192 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 15.2542 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 15.2542 | 4 | yes |
| GO:0051336 | regulation of hydrolase activity | 14.6893 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 14.6893 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 14.1243 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 14.1243 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 14.1243 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 14.1243 | 4 | yes |
| GO:0031399 | regulation of protein modification process | 14.1243 | 6 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 13.5593 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 13.5593 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 12.9944 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 12.9944 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 12.9944 | 5 | yes |
| GO:0045595 | regulation of cell differentiation | 12.9944 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 12.9944 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 12.4294 | 5 | yes |
| GO:0042325 | regulation of phosphorylation | 12.4294 | 7 | yes |
| GO:0001932 | regulation of protein phosphorylation | 11.8644 | 7 | yes |
| GO:0010648 | negative regulation of cell communication | 11.8644 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 11.8644 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 11.8644 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 11.2994 | 4 | yes |
| GO:0051252 | regulation of RNA metabolic process | 11.2994 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 10.7345 | 6 | yes |
| GO:0051338 | regulation of transferase activity | 10.7345 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 10.7345 | 5 | yes |
| GO:0009968 | negative regulation of signal transduction | 10.1695 | 5 | yes |
| GO:0043549 | regulation of kinase activity | 10.1695 | 5 | yes |
| GO:0045597 | positive regulation of cell differentiation | 10.1695 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 9.6045 | 6 | yes |
| GO:0043408 | regulation of MAPK cascade | 9.6045 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 9.6045 | 6 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 9.6045 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 9.6045 | 6 | yes |
| GO:2000026 | regulation of multicellular organismal development | 9.0395 | 4 | yes |
| GO:0031400 | negative regulation of protein modification process | 8.4746 | 7 | yes |
| GO:0060284 | regulation of cell development | 8.4746 | 5 | yes |
| GO:0043087 | regulation of GTPase activity | 7.9096 | 5 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 7.3446 | 6 | yes |
| GO:0010720 | positive regulation of cell development | 7.3446 | 6 | yes |
| GO:0043086 | negative regulation of catalytic activity | 7.3446 | 4 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 7.3446 | 7 | yes |
| GO:0043547 | positive regulation of GTPase activity | 6.7797 | 6 | yes |
| GO:0050767 | regulation of neurogenesis | 6.7797 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 6.7797 | 5 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 6.2147 | 8 | yes |
| GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 6.2147 | 5 | yes |
| GO:0009416 | response to light stimulus | 6.2147 | 4 | yes |
| GO:0042326 | negative regulation of phosphorylation | 6.2147 | 8 | yes |
| GO:0050769 | positive regulation of neurogenesis | 6.2147 | 6 | yes |
| GO:0050890 | cognition | 6.2147 | 4 | yes |
| GO:0051962 | positive regulation of nervous system development | 6.2147 | 5 | yes |
| GO:0007612 | learning | 5.6497 | 4 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 5.6497 | 7 | yes |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 5.0847 | 7 | yes |
| GO:0006469 | negative regulation of protein kinase activity | 3.9548 | 7 | yes |
| GO:0008306 | associative learning | 3.9548 | 5 | yes |
| GO:0033673 | negative regulation of kinase activity | 3.9548 | 6 | yes |
| GO:0051348 | negative regulation of transferase activity | 3.9548 | 5 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 3.9548 | 6 | yes |
| GO:0006913 | nucleocytoplasmic transport | 3.3898 | 5 | yes |
| GO:0043405 | regulation of MAP kinase activity | 3.3898 | 8 | yes |
| GO:0050806 | positive regulation of synaptic transmission | 3.3898 | 5 | yes |
| GO:0051169 | nuclear transport | 3.3898 | 4 | yes |
| GO:0007613 | memory | 2.8249 | 4 | yes |
| GO:0008542 | visual learning | 2.8249 | 4 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 2.2599 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 2.2599 | 5 | yes |
| GO:0043409 | negative regulation of MAPK cascade | 2.2599 | 7 | yes |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 2.2599 | 8 | yes |
| GO:0007616 | long-term memory | 1.6949 | 5 | yes |
| GO:0043407 | negative regulation of MAP kinase activity | 1.6949 | 8 | yes |
| GO:0045744 | negative regulation of G protein-coupled receptor signaling pathway | 1.6949 | 6 | yes |
| GO:0010070 | zygote asymmetric cell division | 1.1299 | 4 | yes |
| GO:0031914 | negative regulation of synaptic plasticity | 1.1299 | 4 | yes |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 1.1299 | 4 | yes |
| GO:0048008 | platelet-derived growth factor receptor signaling pathway | 1.1299 | 6 | yes |
| GO:0060291 | long-term synaptic potentiation | 1.1299 | 4 | yes |
| GO:0070373 | negative regulation of ERK1 and ERK2 cascade | 1.1299 | 8 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in RGS14_HUMAN |
|---|---|---|---|---|
| DOID:114 | heart disease | 2.2599 | 3 | no |
| DOID:0050700 | cardiomyopathy | 1.6949 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.6949 | 5 | no |
| DOID:2843 | long QT syndrome | 1.1299 | 6 | no |
| DOID:0080000 | muscular disease | 1.1299 | 3 | no |
| DOID:3191 | nemaline myopathy | 1.1299 | 7 | no |
| DOID:422 | congenital structural myopathy | 1.1299 | 6 | no |
| DOID:423 | myopathy | 1.1299 | 5 | no |
| DOID:66 | muscle tissue disease | 1.1299 | 4 | no |
| DOID:0050155 | sensory system disease | 1.1299 | 3 | no |
| DOID:574 | peripheral nervous system disease | 1.1299 | 3 | no |
| DOID:870 | neuropathy | 1.1299 | 4 | no |
| DOID:1247 | blood coagulation disease | 1.1299 | 3 | no |
| DOID:2218 | blood platelet disease | 1.1299 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| RAP2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GNA11_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GNAO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNAI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RUFY3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG5_HUMAN | [view interactions] | High throughput | no | no |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP8_HUMAN | [view interactions] | High throughput | no | no |
| IDH3G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR2A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HPCL4_HUMAN | [view interactions] | High throughput | no | no |
| KCAB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG4_HUMAN | [view interactions] | High throughput | no | no |
| COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TB10B_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PSB5_HUMAN | [view interactions] | High throughput | no | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR9_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DHRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MICA1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRC7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LY6H_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRIM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CADH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MLC1_HUMAN | [view interactions] | High throughput | no | no |
| NFH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHRF1_HUMAN | [view interactions] | High throughput | no | no |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UN13A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERIP6_HUMAN | [view interactions] | High throughput | no | no |
| ZC21A_HUMAN | [view interactions] | High throughput | no | yes |
| IP3KA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTY_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCJ10_HUMAN | [view interactions] | High throughput | no | no |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AOFB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CA198_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACO11_HUMAN | [view interactions] | High throughput | no | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYGM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GTR14_HUMAN | [view interactions] | High throughput | no | no |
| GTR3_HUMAN | [view interactions] | High throughput | no | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| GAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BORG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADM4_HUMAN | [view interactions] | High throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MMSA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HIBCH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SV2C_HUMAN | [view interactions] | High throughput | no | no |
| RFIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYAC_HUMAN | [view interactions] | High throughput | no | yes |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ETHE1_HUMAN | [view interactions] | High throughput | no | yes |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP2_HUMAN | [view interactions] | High throughput | no | no |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| THYG_HUMAN | [view interactions] | High throughput | no | no |
| CDIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H14_HUMAN | [view interactions] | High throughput | no | yes |
| PAIRB_HUMAN | [view interactions] | High throughput | no | yes |
| RN214_HUMAN | [view interactions] | High throughput | no | yes |
| RAB18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDHD2_HUMAN | [view interactions] | High throughput | no | yes |
| IPKA_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS12_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASP_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4B_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSF1_HUMAN | [view interactions] | High throughput | no | no |
| TINF2_HUMAN | [view interactions] | High throughput | no | no |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| VIPR2_HUMAN | [view interactions] | High throughput | no | no |
| POTE1_HUMAN | [view interactions] | High throughput | no | no |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| MYL6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ML12B_HUMAN | [view interactions] | High throughput | no | no |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRB_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYL6B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BSN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TMOD2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASB9_HUMAN | [view interactions] | High throughput | no | no |
| MYL9_HUMAN | [view interactions] | High throughput | no | no |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| APOB_HUMAN | [view interactions] | High throughput | no | no |
| LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
| ADDB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRF1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADDG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYL10_HUMAN | [view interactions] | High throughput | no | no |
| CSKI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCLO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA6_HUMAN | [view interactions] | High throughput | no | no |
| NDUS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL15_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYPT2_HUMAN | [view interactions] | High throughput | no | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS4_HUMAN | [view interactions] | Computational | no | no |
| RGS20_HUMAN | [view interactions] | Computational | no | no |
| RGS8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RGS21_HUMAN | [view interactions] | Computational | no | no |
| RGS5_HUMAN | [view interactions] | Computational | no | no |
| RGS10_HUMAN | [view interactions] | Computational | no | yes |
| RGS11_HUMAN | [view interactions] | Computational | no | yes |
| RGS13_HUMAN | [view interactions] | Computational | no | no |
| RAP1B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ITAL_HUMAN | [view interactions] | Computational | no | no |
| RGS7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RGS16_HUMAN | [view interactions] | Computational | no | no |
| RGS17_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RGS19_HUMAN | [view interactions] | Computational | no | yes |
| RGS18_HUMAN | [view interactions] | Computational | no | yes |
| RGS3_HUMAN | [view interactions] | Computational | no | no |
| RGS9_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RGS1_HUMAN | [view interactions] | Computational | no | yes |
| ITAM_HUMAN | [view interactions] | Computational | no | no |
| RGS6_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ITB2_HUMAN | [view interactions] | Computational | no | no |