CALB2_HUMAN
Evidence for PS localization
Functions
Calretinin is a calcium-binding protein which is abundant in auditory neurons. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CALB2_HUMAN |
|---|---|---|---|---|
| GO:0003924 | GTPase activity | 33.3333 | 7 | no |
| GO:0016462 | pyrophosphatase activity | 33.3333 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 33.3333 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 33.3333 | 6 | no |
| GO:0046872 | metal ion binding | 22.2222 | 4 | yes |
| GO:0005525 | GTP binding | 22.2222 | 5 | no |
| GO:0017076 | purine nucleotide binding | 22.2222 | 4 | no |
| GO:0019001 | guanyl nucleotide binding | 22.2222 | 5 | no |
| GO:0019900 | kinase binding | 22.2222 | 4 | no |
| GO:0019901 | protein kinase binding | 22.2222 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.2222 | 4 | no |
| GO:0032561 | guanyl ribonucleotide binding | 22.2222 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0005216 | ion channel activity | 22.2222 | 4 | no |
| GO:0005261 | cation channel activity | 22.2222 | 5 | no |
| GO:0008324 | cation transmembrane transporter activity | 22.2222 | 4 | no |
| GO:0015267 | channel activity | 22.2222 | 4 | no |
| GO:0022890 | inorganic cation transmembrane transporter activity | 22.2222 | 4 | no |
| GO:0046873 | metal ion transmembrane transporter activity | 22.2222 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CALB2_HUMAN |
|---|---|---|---|---|
| GO:0007268 | chemical synaptic transmission | 44.4444 | 6 | no |
| GO:0098916 | anterograde trans-synaptic signaling | 44.4444 | 5 | no |
| GO:0099537 | trans-synaptic signaling | 44.4444 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 44.4444 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.3333 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 33.3333 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 33.3333 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 33.3333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 33.3333 | 4 | no |
| GO:0006996 | organelle organization | 33.3333 | 4 | no |
| GO:0006873 | cellular ion homeostasis | 22.2222 | 4 | yes |
| GO:0006875 | cellular metal ion homeostasis | 22.2222 | 6 | yes |
| GO:0030003 | cellular cation homeostasis | 22.2222 | 5 | yes |
| GO:0048878 | chemical homeostasis | 22.2222 | 4 | yes |
| GO:0050801 | ion homeostasis | 22.2222 | 5 | yes |
| GO:0055065 | metal ion homeostasis | 22.2222 | 7 | yes |
| GO:0055080 | cation homeostasis | 22.2222 | 6 | yes |
| GO:0098771 | inorganic ion homeostasis | 22.2222 | 6 | yes |
| GO:0008104 | protein localization | 22.2222 | 4 | no |
| GO:0010807 | regulation of synaptic vesicle priming | 22.2222 | 6 | no |
| GO:0015031 | protein transport | 22.2222 | 4 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 22.2222 | 5 | no |
| GO:0071702 | organic substance transport | 22.2222 | 4 | no |
| GO:0071705 | nitrogen compound transport | 22.2222 | 4 | no |
| GO:0007010 | cytoskeleton organization | 22.2222 | 5 | no |
| GO:0030030 | cell projection organization | 22.2222 | 4 | no |
| GO:0032990 | cell part morphogenesis | 22.2222 | 4 | no |
| GO:0034330 | cell junction organization | 22.2222 | 4 | no |
| GO:0043269 | regulation of ion transport | 22.2222 | 5 | no |
| GO:0048812 | neuron projection morphogenesis | 22.2222 | 7 | no |
| GO:0048858 | cell projection morphogenesis | 22.2222 | 5 | no |
| GO:0050808 | synapse organization | 22.2222 | 5 | no |
| GO:0051049 | regulation of transport | 22.2222 | 4 | no |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 22.2222 | 6 | no |
| GO:0048523 | negative regulation of cellular process | 22.2222 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NUFP1_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| DGUOK_HUMAN | [view interactions] | High throughput | no | yes |
| KTU_HUMAN | [view interactions] | High throughput | no | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TLX3_HUMAN | [view interactions] | High throughput | no | no |
| HMX2_HUMAN | [view interactions] | High throughput | no | no |
| SNAB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCE1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CCKN_HUMAN | [view interactions] | Computational | no | yes |
| NPY_HUMAN | [view interactions] | Computational | no | yes |
| SMS_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PRVA_HUMAN | [view interactions] | Computational | no | yes |