Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SNAB_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SNAB_HUMAN
GO:0019900 kinase binding 39.2857 4 no
GO:0019905 syntaxin binding 35.7143 4 yes
GO:0019901 protein kinase binding 28.5714 5 no
GO:0046872 metal ion binding 25.0000 4 no
GO:0005509 calcium ion binding 21.4286 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in SNAB_HUMAN
GO:0048522 positive regulation of cellular process 75.0000 4 no
GO:0008104 protein localization 67.8571 4 yes
GO:0010646 regulation of cell communication 60.7143 4 no
GO:0022607 cellular component assembly 60.7143 4 no
GO:0015031 protein transport 57.1429 4 yes
GO:0051128 regulation of cellular component organization 57.1429 4 yes
GO:0071702 organic substance transport 57.1429 4 yes
GO:0071705 nitrogen compound transport 57.1429 4 yes
GO:0006996 organelle organization 57.1429 4 no
GO:0016192 vesicle-mediated transport 53.5714 4 no
GO:0051049 regulation of transport 53.5714 4 no
GO:0061024 membrane organization 53.5714 4 no
GO:0043933 protein-containing complex organization 50.0000 4 yes
GO:0061025 membrane fusion 50.0000 5 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0006886 intracellular protein transport 46.4286 4 yes
GO:0016050 vesicle organization 42.8571 5 no
GO:0050804 modulation of chemical synaptic transmission 42.8571 5 no
GO:0099177 regulation of trans-synaptic signaling 42.8571 4 no
GO:0009893 positive regulation of metabolic process 42.8571 4 no
GO:0009966 regulation of signal transduction 42.8571 4 no
GO:0048523 negative regulation of cellular process 42.8571 4 no
GO:0051171 regulation of nitrogen compound metabolic process 42.8571 4 no
GO:0051246 regulation of protein metabolic process 42.8571 5 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0006906 vesicle fusion 39.2857 6 no
GO:0023056 positive regulation of signaling 39.2857 4 no
GO:0048284 organelle fusion 39.2857 5 no
GO:0051046 regulation of secretion 39.2857 5 no
GO:0065003 protein-containing complex assembly 39.2857 5 no
GO:0090174 organelle membrane fusion 39.2857 6 no
GO:1903530 regulation of secretion by cell 39.2857 4 no
GO:0010604 positive regulation of macromolecule metabolic process 39.2857 5 no
GO:0031323 regulation of cellular metabolic process 39.2857 4 no
GO:0051050 positive regulation of transport 39.2857 4 no
GO:0060627 regulation of vesicle-mediated transport 39.2857 4 no
GO:0044087 regulation of cellular component biogenesis 35.7143 4 yes
GO:0006887 exocytosis 35.7143 4 no
GO:0010647 positive regulation of cell communication 35.7143 5 no
GO:0046903 secretion 35.7143 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 35.7143 5 no
GO:0051247 positive regulation of protein metabolic process 35.7143 6 no
GO:0017157 regulation of exocytosis 35.7143 5 no
GO:0032880 regulation of protein localization 32.1429 5 no
GO:0048278 vesicle docking 32.1429 4 no
GO:0060341 regulation of cellular localization 32.1429 4 no
GO:0031325 positive regulation of cellular metabolic process 32.1429 5 no
GO:0043269 regulation of ion transport 32.1429 5 no
GO:0050806 positive regulation of synaptic transmission 28.5714 5 no
GO:0009892 negative regulation of metabolic process 28.5714 4 no
GO:0019220 regulation of phosphate metabolic process 28.5714 6 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0031399 regulation of protein modification process 28.5714 6 no
GO:0042325 regulation of phosphorylation 28.5714 7 no
GO:0051174 regulation of phosphorus metabolic process 28.5714 5 no
GO:0048584 positive regulation of response to stimulus 28.5714 4 no
GO:0023061 signal release 25.0000 4 no
GO:0009894 regulation of catabolic process 25.0000 4 no
GO:0010038 response to metal ion 25.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 25.0000 5 no
GO:0001932 regulation of protein phosphorylation 25.0000 7 no
GO:0051051 negative regulation of transport 25.0000 4 no
GO:0072657 protein localization to membrane 25.0000 4 no
GO:0048193 Golgi vesicle transport 25.0000 5 no
GO:0007268 chemical synaptic transmission 21.4286 6 yes
GO:0098916 anterograde trans-synaptic signaling 21.4286 5 yes
GO:0099537 trans-synaptic signaling 21.4286 4 yes
GO:0006897 endocytosis 21.4286 5 no
GO:0016079 synaptic vesicle exocytosis 21.4286 4 no
GO:0031344 regulation of cell projection organization 21.4286 5 no
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane 21.4286 4 no
GO:0045055 regulated exocytosis 21.4286 5 no
GO:0048499 synaptic vesicle membrane organization 21.4286 5 no
GO:0099003 vesicle-mediated transport in synapse 21.4286 5 no
GO:0099643 signal release from synapse 21.4286 5 no
GO:0010562 positive regulation of phosphorus metabolic process 21.4286 6 no
GO:0030030 cell projection organization 21.4286 4 no
GO:0033043 regulation of organelle organization 21.4286 5 no
GO:0042327 positive regulation of phosphorylation 21.4286 8 no
GO:0043085 positive regulation of catalytic activity 21.4286 4 no
GO:0043549 regulation of kinase activity 21.4286 5 no
GO:0045937 positive regulation of phosphate metabolic process 21.4286 7 no
GO:0051129 negative regulation of cellular component organization 21.4286 5 no
GO:0051130 positive regulation of cellular component organization 21.4286 5 no
GO:0051248 negative regulation of protein metabolic process 21.4286 6 no
GO:0051336 regulation of hydrolase activity 21.4286 4 no
GO:0051338 regulation of transferase activity 21.4286 4 no
GO:0120036 plasma membrane bounded cell projection organization 21.4286 5 no
GO:1902531 regulation of intracellular signal transduction 21.4286 5 no
GO:1903829 positive regulation of protein localization 21.4286 5 no
GO:0022898 regulation of transmembrane transporter activity 21.4286 4 no
GO:0032412 regulation of ion transmembrane transporter activity 21.4286 5 no
GO:0034762 regulation of transmembrane transport 21.4286 4 no
GO:0034765 regulation of ion transmembrane transport 21.4286 5 no
GO:0043270 positive regulation of ion transport 21.4286 5 no
GO:0044057 regulation of system process 21.4286 4 no
GO:1904062 regulation of cation transmembrane transport 21.4286 6 no
GO:2001257 regulation of cation channel activity 21.4286 6 no
GO:0051047 positive regulation of secretion 21.4286 5 no
GO:1903532 positive regulation of secretion by cell 21.4286 5 no
GO:0043254 regulation of protein-containing complex assembly 17.8571 5 yes
GO:0010807 regulation of synaptic vesicle priming 14.2857 6 yes
GO:0022411 cellular component disassembly 14.2857 4 yes
GO:0032984 protein-containing complex disassembly 14.2857 5 yes
GO:0035494 SNARE complex disassembly 10.7143 6 yes
GO:0035249 synaptic transmission, glutamatergic 7.1429 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in SNAB_HUMAN
DOID:440 neuromuscular disease 7.1429 5 no
DOID:574 peripheral nervous system disease 7.1429 3 no
DOID:870 neuropathy 7.1429 4 no
DOID:0050700 cardiomyopathy 7.1429 4 no
DOID:0060036 intrinsic cardiomyopathy 7.1429 5 no
DOID:114 heart disease 7.1429 3 no
DOID:2843 long QT syndrome 7.1429 6 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TAF1B_HUMAN [view interactions] High throughput no no
SNP23_HUMAN [view entry] [view interactions] High throughput yes no
STX16_HUMAN [view interactions] High throughput no yes
TFEC_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX5_HUMAN [view interactions] High throughput no yes
STX3_HUMAN [view entry] [view interactions] High throughput yes no
AR6P1_HUMAN [view interactions] High throughput no yes
STX1A_HUMAN [view entry] [view interactions] High throughput yes yes
SNP29_HUMAN [view interactions] High throughput no yes
BET1_HUMAN [view interactions] High throughput no no
STX1B_HUMAN [view entry] [view interactions] High throughput yes yes
STX19_HUMAN [view interactions] High throughput no yes
SDCB1_HUMAN [view entry] [view interactions] High throughput yes yes
DG2L6_HUMAN [view interactions] High throughput no no
CLC10_HUMAN [view interactions] High throughput no yes
CISD2_HUMAN [view interactions] High throughput no yes
DHB13_HUMAN [view interactions] High throughput no yes
CXB5_HUMAN [view interactions] High throughput no no
CR3L1_HUMAN [view interactions] High throughput no yes
AL5AP_HUMAN [view interactions] High throughput no no
SIGL5_HUMAN [view interactions] High throughput no no
SYT2_HUMAN [view entry] [view interactions] High throughput yes no
TM139_HUMAN [view interactions] High throughput no no
PKHO1_HUMAN [view interactions] High throughput no no
F209A_HUMAN [view interactions] High throughput no no
SYT1_HUMAN [view entry] [view interactions] High throughput yes no
LEUTX_HUMAN [view interactions] High throughput no no
STX2_HUMAN [view interactions] High throughput no no
KCNN3_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
HAX1_HUMAN [view interactions] High throughput no no
DGUOK_HUMAN [view interactions] High throughput no yes
KTU_HUMAN [view interactions] High throughput no yes
VAMP4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
APEX1_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
CTBP2_HUMAN [view interactions] High throughput no no
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
SNAA_HUMAN [view entry] [view interactions] High throughput yes yes
VAMP5_HUMAN [view interactions] High throughput no no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
SNAG_HUMAN [view entry] [view interactions] High throughput yes yes
CALB2_HUMAN [view entry] [view interactions] High throughput yes yes
SC22B_HUMAN [view entry] [view interactions] High throughput yes no
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
SNP25_HUMAN [view entry] [view interactions] High throughput yes yes
VAMP1_HUMAN [view interactions] High throughput no no
STX6_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
NPHP4_HUMAN [view interactions] High throughput no yes
STX12_HUMAN [view entry] [view interactions] High throughput yes yes
NUFP1_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
VAMP2_HUMAN [view entry] [view interactions] High throughput yes no
BCAR1_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes