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SDCB1_HUMAN

Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed). May also play a role in vesicular trafficking (PubMed). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed). [View more on UniProt]

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No data found.

ELM instance Name Type Start End Partner
ELMI002343 LIG_LYPXL_S_1 LIG 3 7 -
ELMI002344 LIG_LYPXL_S_1 LIG 45 49 -
ELMI002345 LIG_LYPXL_S_1 LIG 49 53 -
ELMI002343 LIG_LYPXL_S_1 LIG 3 7 -
ELMI002344 LIG_LYPXL_S_1 LIG 45 49 -
ELMI002345 LIG_LYPXL_S_1 LIG 49 53 -

Molecular function

Term Name % Distance from the top of the tree Annotated in SDCB1_HUMAN
GO:0043168 anion binding 22.7273 4 yes
GO:0043169 cation binding 22.7273 4 no
GO:0046872 metal ion binding 22.7273 5 no
GO:0019900 kinase binding 22.7273 4 no
GO:0001664 G protein-coupled receptor binding 9.0909 4 yes
GO:0035254 glutamate receptor binding 6.8182 4 yes
GO:0046875 ephrin receptor binding 6.8182 4 yes
GO:0035091 phosphatidylinositol binding 5.6818 4 yes
GO:0070851 growth factor receptor binding 5.6818 4 yes
GO:0005126 cytokine receptor binding 4.5455 4 yes
GO:0046982 protein heterodimerization activity 4.5455 4 yes
GO:1901981 phosphatidylinositol phosphate binding 4.5455 5 yes
GO:1902936 phosphatidylinositol bisphosphate binding 4.5455 6 yes
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3.4091 5 yes
GO:0005109 frizzled binding 2.2727 5 yes
GO:0005137 interleukin-5 receptor binding 2.2727 5 yes
GO:0035255 ionotropic glutamate receptor binding 2.2727 5 yes
GO:0042043 neurexin family protein binding 2.2727 4 yes
GO:0045545 syndecan binding 2.2727 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SDCB1_HUMAN
GO:0048522 positive regulation of cellular process 59.0909 4 yes
GO:0010646 regulation of cell communication 54.5455 4 yes
GO:0060255 regulation of macromolecule metabolic process 47.7273 4 yes
GO:0048523 negative regulation of cellular process 47.7273 4 yes
GO:0080090 regulation of primary metabolic process 42.0455 4 yes
GO:0031323 regulation of cellular metabolic process 42.0455 4 yes
GO:0051128 regulation of cellular component organization 42.0455 4 yes
GO:0009893 positive regulation of metabolic process 39.7727 4 yes
GO:0009966 regulation of signal transduction 39.7727 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 36.3636 5 no
GO:0006996 organelle organization 35.2273 4 yes
GO:0051049 regulation of transport 35.2273 4 yes
GO:0022607 cellular component assembly 34.0909 4 yes
GO:0009889 regulation of biosynthetic process 32.9545 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 32.9545 5 yes
GO:0010647 positive regulation of cell communication 32.9545 5 yes
GO:0023056 positive regulation of signaling 32.9545 4 yes
GO:0031325 positive regulation of cellular metabolic process 32.9545 5 yes
GO:0031326 regulation of cellular biosynthetic process 32.9545 5 yes
GO:0051246 regulation of protein metabolic process 31.8182 5 no
GO:0008104 protein localization 31.8182 4 yes
GO:0010468 regulation of gene expression 31.8182 6 yes
GO:1902531 regulation of intracellular signal transduction 30.6818 5 yes
GO:0048584 positive regulation of response to stimulus 30.6818 4 yes
GO:0009892 negative regulation of metabolic process 26.1364 4 yes
GO:0030030 cell projection organization 26.1364 4 yes
GO:0050804 modulation of chemical synaptic transmission 25.0000 5 no
GO:0099177 regulation of trans-synaptic signaling 25.0000 4 no
GO:0051247 positive regulation of protein metabolic process 25.0000 6 no
GO:0009967 positive regulation of signal transduction 25.0000 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 yes
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 yes
GO:0044087 regulation of cellular component biogenesis 25.0000 4 yes
GO:0031399 regulation of protein modification process 23.8636 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.7273 5 yes
GO:0019220 regulation of phosphate metabolic process 22.7273 6 yes
GO:0042325 regulation of phosphorylation 22.7273 7 yes
GO:0051174 regulation of phosphorus metabolic process 22.7273 5 yes
GO:0010648 negative regulation of cell communication 21.5909 5 no
GO:0023057 negative regulation of signaling 21.5909 4 no
GO:0031401 positive regulation of protein modification process 21.5909 7 no
GO:0042981 regulation of apoptotic process 21.5909 5 no
GO:0043067 regulation of programmed cell death 21.5909 4 no
GO:0007010 cytoskeleton organization 21.5909 5 yes
GO:0051050 positive regulation of transport 21.5909 4 yes
GO:0099536 synaptic signaling 20.4545 4 yes
GO:0099537 trans-synaptic signaling 20.4545 5 yes
GO:2000145 regulation of cell motility 20.4545 4 yes
GO:0061024 membrane organization 20.4545 4 no
GO:0001932 regulation of protein phosphorylation 20.4545 7 no
GO:0031344 regulation of cell projection organization 20.4545 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 20.4545 6 no
GO:0009891 positive regulation of biosynthetic process 20.4545 5 no
GO:0031328 positive regulation of cellular biosynthetic process 20.4545 6 no
GO:0033043 regulation of organelle organization 20.4545 5 yes
GO:0060627 regulation of vesicle-mediated transport 19.3182 4 yes
GO:0098916 anterograde trans-synaptic signaling 19.3182 6 yes
GO:0120036 plasma membrane bounded cell projection organization 19.3182 5 yes
GO:0007268 chemical synaptic transmission 19.3182 7 yes
GO:0010562 positive regulation of phosphorus metabolic process 19.3182 6 yes
GO:0030334 regulation of cell migration 19.3182 5 yes
GO:0042327 positive regulation of phosphorylation 19.3182 8 yes
GO:0045937 positive regulation of phosphate metabolic process 19.3182 7 yes
GO:0051252 regulation of RNA metabolic process 19.3182 5 yes
GO:0051726 regulation of cell cycle 18.1818 4 yes
GO:0141124 intracellular signaling cassette 18.1818 4 yes
GO:1902533 positive regulation of intracellular signal transduction 18.1818 6 yes
GO:0009890 negative regulation of biosynthetic process 18.1818 5 yes
GO:0042127 regulation of cell population proliferation 18.1818 4 yes
GO:0051129 negative regulation of cellular component organization 18.1818 5 yes
GO:2001141 regulation of RNA biosynthetic process 17.0455 6 yes
GO:0006355 regulation of DNA-templated transcription 17.0455 7 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 17.0455 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 17.0455 6 yes
GO:0051130 positive regulation of cellular component organization 17.0455 5 yes
GO:1903530 regulation of secretion by cell 14.7727 4 yes
GO:0045595 regulation of cell differentiation 14.7727 4 yes
GO:0051046 regulation of secretion 14.7727 5 yes
GO:0044089 positive regulation of cellular component biogenesis 13.6364 5 yes
GO:0051240 positive regulation of multicellular organismal process 13.6364 4 yes
GO:2000147 positive regulation of cell motility 12.5000 5 yes
GO:0030335 positive regulation of cell migration 12.5000 6 yes
GO:0040017 positive regulation of locomotion 12.5000 4 yes
GO:0043408 regulation of MAPK cascade 12.5000 6 yes
GO:0072657 protein localization to membrane 11.3636 4 yes
GO:1902115 regulation of organelle assembly 11.3636 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 11.3636 8 yes
GO:0010638 positive regulation of organelle organization 11.3636 6 yes
GO:0017157 regulation of exocytosis 11.3636 5 yes
GO:0030100 regulation of endocytosis 11.3636 5 yes
GO:0051051 negative regulation of transport 11.3636 4 yes
GO:0051094 positive regulation of developmental process 11.3636 4 yes
GO:0001558 regulation of cell growth 10.2273 4 yes
GO:0006508 proteolysis 10.2273 4 yes
GO:0007264 small GTPase-mediated signal transduction 10.2273 5 yes
GO:0008284 positive regulation of cell population proliferation 10.2273 5 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 10.2273 5 yes
GO:1903532 positive regulation of secretion by cell 9.0909 5 yes
GO:0043410 positive regulation of MAPK cascade 9.0909 7 yes
GO:0051047 positive regulation of secretion 9.0909 5 yes
GO:0051253 negative regulation of RNA metabolic process 9.0909 6 yes
GO:0045597 positive regulation of cell differentiation 7.9545 5 yes
GO:0090150 establishment of protein localization to membrane 6.8182 4 yes
GO:1902117 positive regulation of organelle assembly 6.8182 6 yes
GO:1902679 negative regulation of RNA biosynthetic process 6.8182 7 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 6.8182 9 yes
GO:0030031 cell projection assembly 6.8182 5 yes
GO:0045892 negative regulation of DNA-templated transcription 6.8182 8 yes
GO:0045921 positive regulation of exocytosis 6.8182 6 yes
GO:0045927 positive regulation of growth 6.8182 4 yes
GO:0048259 regulation of receptor-mediated endocytosis 6.8182 6 yes
GO:0006605 protein targeting 5.6818 4 yes
GO:0007346 regulation of mitotic cell cycle 5.6818 5 yes
GO:0030307 positive regulation of cell growth 5.6818 5 yes
GO:0120031 plasma membrane bounded cell projection assembly 4.5455 6 yes
GO:0002090 regulation of receptor internalization 4.5455 7 yes
GO:0045806 negative regulation of endocytosis 4.5455 5 yes
GO:0046328 regulation of JNK cascade 4.5455 7 yes
GO:0048261 negative regulation of receptor-mediated endocytosis 4.5455 6 yes
GO:0090287 regulation of cellular response to growth factor stimulus 3.4091 4 yes
GO:1903541 regulation of exosomal secretion 3.4091 6 yes
GO:1903543 positive regulation of exosomal secretion 3.4091 6 yes
GO:1903551 regulation of extracellular exosome assembly 3.4091 6 yes
GO:1903553 positive regulation of extracellular exosome assembly 3.4091 7 yes
GO:0002091 negative regulation of receptor internalization 3.4091 7 yes
GO:0006612 protein targeting to membrane 3.4091 5 yes
GO:0010717 regulation of epithelial to mesenchymal transition 3.4091 5 yes
GO:0046330 positive regulation of JNK cascade 3.4091 8 yes
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.2727 5 yes
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.2727 6 yes
GO:0099054 presynapse assembly 2.2727 5 yes
GO:0099172 presynapse organization 2.2727 4 yes
GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 2.2727 5 yes
GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 2.2727 5 yes
GO:0006930 substrate-dependent cell migration, cell extension 2.2727 7 yes
GO:0007265 Ras protein signal transduction 2.2727 6 yes
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.2727 5 yes
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 2.2727 6 yes
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 2.2727 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SDCB1_HUMAN [view entry] [view interactions] Low throughput yes yes
NECT1_HUMAN [view interactions] Low throughput no yes
EPHA7_HUMAN [view entry] [view interactions] Low throughput yes no
EFNB1_HUMAN [view interactions] Low throughput no yes
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
TGFA_HUMAN [view interactions] Low throughput no yes
JAG1_HUMAN [view interactions] Low throughput no no
SOX4_HUMAN [view interactions] Low throughput no yes
FZD3_HUMAN [view interactions] Low throughput no yes
FZD7_HUMAN [view interactions] Low throughput no yes
SDC2_HUMAN [view entry] [view interactions] Low throughput yes yes
FZD8_HUMAN [view interactions] Low throughput no yes
CD6_HUMAN [view interactions] Low throughput no no
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
EFNB3_HUMAN [view entry] [view interactions] Low throughput yes yes
SDC4_HUMAN [view interactions] Low throughput no yes
IL5RA_HUMAN [view interactions] Low throughput no no
GRIK2_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIK1_HUMAN [view entry] [view interactions] Low throughput yes yes
ULK1_HUMAN [view interactions] Low throughput no no
RAB5A_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRJ_HUMAN [view interactions] Low throughput no yes
MERL_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
GPR37_HUMAN [view interactions] Low throughput no no
PTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
SDC1_HUMAN [view interactions] Low throughput no no
TRAF6_HUMAN [view entry] [view interactions] Low throughput yes yes
ILK_HUMAN [view interactions] Low throughput no no
CD63_HUMAN [view interactions] Low throughput no no
CD9_HUMAN [view entry] [view interactions] Low throughput yes no
YAP1_HUMAN [view interactions] Low throughput no yes
HXA7_HUMAN [view interactions] High throughput no no
SNAB_HUMAN [view entry] [view interactions] High throughput yes yes
RP9_HUMAN [view interactions] High throughput no yes
FADD_HUMAN [view interactions] High throughput no yes
MK09_HUMAN [view interactions] High throughput no yes
HMBX1_HUMAN [view interactions] High throughput no yes
NC2A_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
GGPPS_HUMAN [view interactions] High throughput no yes
CT451_HUMAN [view interactions] High throughput no no
ZSC23_HUMAN [view interactions] High throughput no no
SWET1_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
GSC2_HUMAN [view interactions] High throughput no no
ZN343_HUMAN [view interactions] High throughput no yes
FAM9A_HUMAN [view interactions] High throughput no no
MOFA1_HUMAN [view interactions] High throughput no yes
RPIA_HUMAN [view interactions] High throughput no yes
ZMY12_HUMAN [view interactions] High throughput no no
ARFP2_HUMAN [view interactions] High throughput no no
ZN660_HUMAN [view interactions] High throughput no no
TMM17_HUMAN [view interactions] High throughput no yes
TM276_HUMAN [view interactions] High throughput no no
CC106_HUMAN [view interactions] High throughput no no
PDLI4_HUMAN [view entry] [view interactions] High throughput yes yes
IBP6_HUMAN [view interactions] High throughput no yes
FHL3_HUMAN [view interactions] High throughput no no
PANKY_HUMAN [view interactions] High throughput no no
RIR2_HUMAN [view interactions] High throughput no no
CHM1A_HUMAN [view entry] [view interactions] High throughput yes no
CBR3_HUMAN [view entry] [view interactions] High throughput yes yes
LUR1L_HUMAN [view interactions] High throughput no no
RPC10_HUMAN [view interactions] High throughput no yes
CTDS1_HUMAN [view interactions] High throughput no no
GET4_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
KRA15_HUMAN [view interactions] High throughput no no
PIHD2_HUMAN [view interactions] High throughput no no
LDB2_HUMAN [view interactions] High throughput no yes
PSME2_HUMAN [view interactions] High throughput no no
ZN485_HUMAN [view interactions] High throughput no no
PSB3_HUMAN [view interactions] High throughput no yes
EXOS4_HUMAN [view interactions] High throughput no yes
PHF11_HUMAN [view interactions] High throughput no no
RPB11_HUMAN [view interactions] High throughput no no
YIF1A_HUMAN [view interactions] High throughput no yes
CHIC2_HUMAN [view interactions] High throughput no no
SEPT1_HUMAN [view interactions] High throughput no no
KCNV1_HUMAN [view interactions] High throughput no no
TMCO2_HUMAN [view interactions] High throughput no no
TCF21_HUMAN [view interactions] High throughput no yes
BRNP2_HUMAN [view interactions] High throughput no no
MYLIP_HUMAN [view interactions] High throughput no no
EGLN1_HUMAN [view entry] [view interactions] High throughput yes yes
KTBL1_HUMAN [view interactions] High throughput no no
SP8_HUMAN [view interactions] High throughput no no
RRS1_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
GKAP1_HUMAN [view interactions] High throughput no no
IFNL3_HUMAN [view interactions] High throughput no no
GRCR1_HUMAN [view interactions] High throughput no no
TBC3H_HUMAN [view interactions] High throughput no no
TCP4_HUMAN [view interactions] High throughput no yes
ABCB6_HUMAN [view interactions] High throughput no yes
ID3_HUMAN [view interactions] High throughput no yes
AFF4_HUMAN [view interactions] High throughput no yes
EMIL3_HUMAN [view interactions] High throughput no yes
HDAC7_HUMAN [view interactions] High throughput no no
SYPL1_HUMAN [view interactions] High throughput no yes
OTUB2_HUMAN [view interactions] High throughput no no
C2C2L_HUMAN [view interactions] High throughput no yes
G3ST1_HUMAN [view interactions] High throughput no no
HUS1_HUMAN [view interactions] High throughput no yes
NECT3_HUMAN [view entry] [view interactions] High throughput yes yes
HHAT_HUMAN [view interactions] High throughput no yes
PP6R2_HUMAN [view interactions] High throughput no no
K1C14_HUMAN [view interactions] High throughput no no
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
LERL1_HUMAN [view interactions] High throughput no no
ZEP1_HUMAN [view interactions] High throughput no yes
N4BP3_HUMAN [view interactions] High throughput no yes
ZN768_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
ODAM_HUMAN [view interactions] High throughput no no
AIM2_HUMAN [view interactions] High throughput no no
RPRM_HUMAN [view interactions] High throughput no no
CNOT1_HUMAN [view interactions] High throughput no yes
RTL8B_HUMAN [view interactions] High throughput no no
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
MKRN1_HUMAN [view interactions] High throughput no no
TMED2_HUMAN [view interactions] High throughput no yes
PDZ1I_HUMAN [view interactions] High throughput no no
JUNB_HUMAN [view interactions] High throughput no yes
SFT2A_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
DERL3_HUMAN [view interactions] High throughput no yes
SDCG8_HUMAN [view interactions] High throughput no yes
CAV2_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
SYS1_HUMAN [view interactions] High throughput no yes
NPC1_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
TFP11_HUMAN [view interactions] High throughput no no
FRIH_HUMAN [view entry] [view interactions] High throughput yes yes
RIC8A_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
GRIA3_HUMAN [view entry] [view interactions] High throughput yes yes
SPRE1_HUMAN [view interactions] High throughput no yes
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
GRM4_HUMAN [view interactions] High throughput no no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
GRM7_HUMAN [view entry] [view interactions] High throughput yes no
ATX1_HUMAN [view interactions] High throughput no yes
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
WDR91_HUMAN [view entry] [view interactions] High throughput yes no
GRM6_HUMAN [view interactions] High throughput no no
ESR1_HUMAN [view interactions] High throughput no no
GRM3_HUMAN [view entry] [view interactions] High throughput yes no
S15A4_HUMAN [view interactions] High throughput no yes
GRIA1_HUMAN [view entry] [view interactions] High throughput yes yes
MYPC2_HUMAN [view interactions] High throughput no no
CD3D_HUMAN [view interactions] High throughput no no
FYN_HUMAN [view entry] [view interactions] High throughput yes no
HSC20_HUMAN [view interactions] High throughput no yes
LCOR_HUMAN [view interactions] High throughput no yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
SCLT1_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
H2B1C_HUMAN [view interactions] High throughput no yes
C102B_HUMAN [view interactions] High throughput no yes
SWAP1_HUMAN [view interactions] High throughput no no
WASL_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
TRAF5_HUMAN [view interactions] High throughput no yes
TRI38_HUMAN [view interactions] High throughput no yes
ERIC2_HUMAN [view interactions] High throughput no no
CEP55_HUMAN [view interactions] High throughput no yes
CDIPT_HUMAN [view entry] [view interactions] High throughput yes yes
FOXP2_HUMAN [view interactions] High throughput no yes
PPIP1_HUMAN [view interactions] High throughput no no
ST1B1_HUMAN [view interactions] High throughput no no
SSNA1_HUMAN [view interactions] High throughput no no
RTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT14_HUMAN [view interactions] High throughput no yes
CAPS1_HUMAN [view entry] [view interactions] High throughput yes yes
HSBP1_HUMAN [view interactions] High throughput no no
ENTR1_HUMAN [view interactions] High throughput no no
KLHL2_HUMAN [view interactions] High throughput no no
TRIM1_HUMAN [view interactions] High throughput no no
KCNH1_HUMAN [view entry] [view interactions] High throughput yes yes
GNMT_HUMAN [view interactions] High throughput no no
NADK_HUMAN [view interactions] High throughput no yes
NECA2_HUMAN [view entry] [view interactions] High throughput yes yes
LDOC1_HUMAN [view interactions] High throughput no no
PR40A_HUMAN [view interactions] High throughput no no
HPRT_HUMAN [view interactions] High throughput no yes
HOMEZ_HUMAN [view interactions] High throughput no no
CRYAA_HUMAN [view interactions] High throughput no no
KR103_HUMAN [view interactions] High throughput no no
FRIL_HUMAN [view interactions] High throughput no yes
CBY2_HUMAN [view interactions] High throughput no no
HNRPC_HUMAN [view interactions] High throughput no yes
TRI27_HUMAN [view interactions] High throughput no yes
SCML1_HUMAN [view interactions] High throughput no no
KRA59_HUMAN [view interactions] High throughput no no
MGLL_HUMAN [view interactions] High throughput no yes
CDD_HUMAN [view interactions] High throughput no no
SNG1_HUMAN [view entry] [view interactions] High throughput yes yes
DCTD_HUMAN [view interactions] High throughput no yes
GSG1_HUMAN [view interactions] High throughput no no
T23O_HUMAN [view interactions] High throughput no no
MATN4_HUMAN [view interactions] High throughput no no
HXA1_HUMAN [view interactions] High throughput no no
RALY_HUMAN [view interactions] High throughput no yes
5NTC_HUMAN [view interactions] High throughput no yes
CEP85_HUMAN [view interactions] High throughput no no
KR107_HUMAN [view interactions] High throughput no no
RPR1A_HUMAN [view interactions] High throughput no yes
PTPS_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
REL_HUMAN [view interactions] High throughput no yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
SRS11_HUMAN [view interactions] High throughput no yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
TLE5_HUMAN [view interactions] High throughput no no
PDE9A_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
BEND7_HUMAN [view interactions] High throughput no no
TRI32_HUMAN [view entry] [view interactions] High throughput yes yes
MOBP_HUMAN [view interactions] High throughput no no
CACO2_HUMAN [view interactions] High throughput no yes
CTBP2_HUMAN [view interactions] High throughput no no
IKZF1_HUMAN [view interactions] High throughput no no
WASH1_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
TARG1_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
PPARA_HUMAN [view interactions] High throughput no yes
SRSF7_HUMAN [view interactions] High throughput no yes
ZTRF1_HUMAN [view interactions] High throughput no no
KLH12_HUMAN [view interactions] High throughput no no
ITF2_HUMAN [view interactions] High throughput no yes
P5CR3_HUMAN [view interactions] High throughput no no
AN36B_HUMAN [view interactions] High throughput no no
RUN3A_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
MYOME_HUMAN [view interactions] High throughput no no
ITA4_HUMAN [view interactions] High throughput no no
KHDR2_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
ANR40_HUMAN [view interactions] High throughput no yes
TSN3_HUMAN [view interactions] High throughput no yes
NKAP1_HUMAN [view interactions] High throughput no yes
SYRC_HUMAN [view interactions] High throughput no yes
KCTD1_HUMAN [view interactions] High throughput no no
SYIC_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
SYQ_HUMAN [view interactions] High throughput no yes
NT2NA_HUMAN [view interactions] High throughput no no
SYEP_HUMAN [view interactions] High throughput no yes
SIAH1_HUMAN [view interactions] High throughput no yes
AIMP2_HUMAN [view interactions] High throughput no yes
PHC2_HUMAN [view interactions] High throughput no yes
SYDC_HUMAN [view interactions] High throughput no yes
IHO1_HUMAN [view interactions] High throughput no no
SYMC_HUMAN [view interactions] High throughput no yes
FAM9B_HUMAN [view interactions] High throughput no no
SYTC2_HUMAN [view interactions] High throughput no yes
IN80E_HUMAN [view interactions] High throughput no yes
AIMP1_HUMAN [view interactions] High throughput no yes
KCTD6_HUMAN [view interactions] High throughput no yes
MCA3_HUMAN [view interactions] High throughput no yes
PNMA1_HUMAN [view interactions] High throughput no yes
SYLC_HUMAN [view interactions] High throughput no yes
FAD1_HUMAN [view interactions] High throughput no yes
ANR28_HUMAN [view interactions] High throughput no no
ZBT8A_HUMAN [view interactions] High throughput no yes
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
ENOX1_HUMAN [view interactions] High throughput no no
TNR3_HUMAN [view interactions] High throughput no yes
TM239_HUMAN [view interactions] High throughput no no
WRP73_HUMAN [view interactions] High throughput no no
EDAD_HUMAN [view entry] [view interactions] High throughput yes yes
UNK_HUMAN [view interactions] High throughput no yes
TEKT1_HUMAN [view interactions] High throughput no no
IF16_HUMAN [view interactions] High throughput no no
TIFA_HUMAN [view interactions] High throughput no yes
SAMD1_HUMAN [view interactions] High throughput no no
CKLF5_HUMAN [view interactions] High throughput no yes
MANS1_HUMAN [view interactions] High throughput no yes
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
GPC5B_HUMAN [view entry] [view interactions] High throughput yes no
MTNB_HUMAN [view interactions] High throughput no yes
PCDBB_HUMAN [view interactions] High throughput no no
REEP6_HUMAN [view interactions] High throughput no no
PCDGG_HUMAN [view interactions] High throughput no no
MR1L1_HUMAN [view interactions] High throughput no no
FA8A1_HUMAN [view interactions] High throughput no yes
F118B_HUMAN [view interactions] High throughput no yes
PCDGD_HUMAN [view interactions] High throughput no no
TRI54_HUMAN [view interactions] High throughput no no
RUSF1_HUMAN [view interactions] High throughput no yes
DCTP1_HUMAN [view interactions] High throughput no no
TR10A_HUMAN [view interactions] High throughput no no
ROP1A_HUMAN [view interactions] High throughput no no
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
ZCC17_HUMAN [view interactions] High throughput no yes
LITAF_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
TM223_HUMAN [view interactions] High throughput no yes
LZTL1_HUMAN [view interactions] High throughput no no
TEDC2_HUMAN [view interactions] High throughput no no
CUTC_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
F118A_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
THG1_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
CGAS_HUMAN [view interactions] High throughput no yes
CGBP1_HUMAN [view interactions] High throughput no yes
SEPT3_HUMAN [view interactions] High throughput no no
H4_HUMAN [view interactions] High throughput no yes
PUF60_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
NAGK_HUMAN [view interactions] High throughput no no
ZBT7B_HUMAN [view interactions] High throughput no no
PNMA2_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
WASC3_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
HMGB3_HUMAN [view interactions] High throughput no no
CTIP_HUMAN [view interactions] High throughput no no
TFIP8_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
MBD3_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
LEG2_HUMAN [view interactions] High throughput no no
PCDG7_HUMAN [view interactions] High throughput no no
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
SYK_HUMAN [view interactions] High throughput no yes
RINI_HUMAN [view interactions] High throughput no yes
INGR1_HUMAN [view interactions] High throughput no no
UB2R1_HUMAN [view interactions] High throughput no yes
EDAR_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
RN149_HUMAN [view interactions] High throughput no no
CLK2_HUMAN [view interactions] High throughput no yes
FFAR1_HUMAN [view interactions] High throughput no no
CLK3_HUMAN [view interactions] High throughput no yes
LEG1_HUMAN [view interactions] High throughput no yes
LSM6_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
PRS10_HUMAN [view interactions] High throughput no yes
HBA_HUMAN [view interactions] High throughput no no
SET_HUMAN [view interactions] High throughput no yes
HBD_HUMAN [view interactions] High throughput no no
MD2L1_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
DMC1_HUMAN [view interactions] High throughput no no
INKA1_HUMAN [view interactions] High throughput no no
TKFC_HUMAN [view interactions] High throughput no no
IFM1_HUMAN [view interactions] High throughput no no
B2L15_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
CT455_HUMAN [view interactions] High throughput no no
TM192_HUMAN [view interactions] High throughput no yes
CT45A_HUMAN [view interactions] High throughput no no
PDE2A_HUMAN [view entry] [view interactions] High throughput yes yes
GPT11_HUMAN [view interactions] High throughput no no
LEG3_HUMAN [view interactions] High throughput no yes
EIF1A_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
SR1IP_HUMAN [view interactions] High throughput no no
RHOJ_HUMAN [view interactions] High throughput no yes
PR38A_HUMAN [view interactions] High throughput no no
RHOQ_HUMAN [view interactions] High throughput no no
CT453_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
ZCH10_HUMAN [view interactions] High throughput no yes
RHOU_HUMAN [view interactions] High throughput no no
AN32B_HUMAN [view interactions] High throughput no yes
RHOH_HUMAN [view interactions] High throughput no yes
OSTF1_HUMAN [view interactions] High throughput no yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
EAF1_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
IF5A2_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
CK068_HUMAN [view interactions] High throughput no yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
CDCP1_HUMAN [view interactions] High throughput no yes
RHOC_HUMAN [view interactions] High throughput no no
AIRIM_HUMAN [view interactions] High throughput no yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
PRR13_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
MMTA2_HUMAN [view interactions] High throughput no yes
FOXA1_HUMAN [view interactions] High throughput no no
TNKS1_HUMAN [view interactions] High throughput no yes
MALT1_HUMAN [view interactions] High throughput no no
SCG3_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
HSF2B_HUMAN [view interactions] High throughput no yes
SNIP1_HUMAN [view interactions] High throughput no no
PHS_HUMAN [view interactions] High throughput no yes
CDK7_HUMAN [view interactions] High throughput no yes
AR6P1_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
SRSF3_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
UB2R2_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
DYLT1_HUMAN [view interactions] High throughput no no
GOLI_HUMAN [view interactions] High throughput no yes
HOME3_HUMAN [view entry] [view interactions] High throughput yes yes
CDN2D_HUMAN [view interactions] High throughput no no
GRM2_HUMAN [view entry] [view interactions] High throughput yes yes
TSN_HUMAN [view interactions] High throughput no yes
CADM1_HUMAN [view entry] [view interactions] High throughput yes no
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
SPCS_HUMAN [view interactions] High throughput no no
MEOX1_HUMAN [view interactions] High throughput no no
SNP25_HUMAN [view entry] [view interactions] High throughput yes yes
ONCO_HUMAN [view interactions] High throughput no no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
S100B_HUMAN [view entry] [view interactions] High throughput yes yes
SYHM_HUMAN [view entry] [view interactions] High throughput yes yes
CABP5_HUMAN [view interactions] High throughput no no
VAMP2_HUMAN [view entry] [view interactions] High throughput yes no
UBB_HUMAN [view entry] [view interactions] High throughput yes yes
SYNM_HUMAN [view interactions] High throughput no yes
PCH2_HUMAN [view interactions] High throughput no no
H14_HUMAN [view interactions] High throughput no yes
CRX_HUMAN [view interactions] High throughput no no
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
MINY3_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
KRA13_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
HEXI2_HUMAN [view interactions] High throughput no yes
ACTC_HUMAN [view interactions] High throughput no no
SRCRL_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
SPXN3_HUMAN [view interactions] High throughput no no
PERI_HUMAN [view entry] [view interactions] High throughput yes no
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
NAA40_HUMAN [view interactions] High throughput no no
RL22_HUMAN [view entry] [view interactions] High throughput yes no
SQSTM_HUMAN [view interactions] High throughput no yes
IF5A1_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
TP8L3_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
OPTN_HUMAN [view interactions] High throughput no yes
KBTB4_HUMAN [view interactions] High throughput no yes
PCY1A_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
DX39B_HUMAN [view interactions] High throughput no no
RAB25_HUMAN [view interactions] High throughput no no
UBE2K_HUMAN [view interactions] High throughput no yes
FHL5_HUMAN [view interactions] High throughput no no