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SDCB1_HUMAN

Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed). May also play a role in vesicular trafficking (PubMed). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed). [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI002343 LIG_LYPXL_S_1 LIG 3 7 -
ELMI002344 LIG_LYPXL_S_1 LIG 45 49 -
ELMI002345 LIG_LYPXL_S_1 LIG 49 53 -

Molecular function

Term Name % Distance from the top of the tree Annotated in SDCB1_HUMAN
GO:0019900 kinase binding 25.0000 4 no
GO:0019901 protein kinase binding 21.4286 5 no
GO:0046872 metal ion binding 20.2381 4 no
GO:0001664 G protein-coupled receptor binding 9.5238 4 yes
GO:0046875 ephrin receptor binding 7.1429 4 yes
GO:0070851 growth factor receptor binding 7.1429 4 yes
GO:0035091 phosphatidylinositol binding 5.9524 4 yes
GO:0046982 protein heterodimerization activity 4.7619 4 yes
GO:1901981 phosphatidylinositol phosphate binding 4.7619 5 yes
GO:1902936 phosphatidylinositol bisphosphate binding 4.7619 6 yes
GO:0005126 cytokine receptor binding 3.5714 4 yes
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3.5714 4 yes
GO:0005109 frizzled binding 2.3810 5 yes
GO:0005137 interleukin-5 receptor binding 2.3810 5 yes
GO:0042043 neurexin family protein binding 2.3810 4 yes
GO:0045545 syndecan binding 2.3810 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SDCB1_HUMAN
GO:0048522 positive regulation of cellular process 52.3810 4 yes
GO:0010646 regulation of cell communication 51.1905 4 yes
GO:0060255 regulation of macromolecule metabolic process 47.6190 4 yes
GO:0048523 negative regulation of cellular process 46.4286 4 yes
GO:0080090 regulation of primary metabolic process 45.2381 4 yes
GO:0031323 regulation of cellular metabolic process 44.0476 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 44.0476 4 yes
GO:0009966 regulation of signal transduction 39.2857 4 yes
GO:0006996 organelle organization 38.0952 4 yes
GO:0009893 positive regulation of metabolic process 38.0952 4 yes
GO:0051128 regulation of cellular component organization 38.0952 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 36.9048 5 yes
GO:0051049 regulation of transport 36.9048 4 yes
GO:0051246 regulation of protein metabolic process 35.7143 5 yes
GO:0008104 protein localization 34.5238 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 34.5238 5 yes
GO:0010468 regulation of gene expression 32.1429 5 yes
GO:1902531 regulation of intracellular signal transduction 32.1429 5 yes
GO:0022607 cellular component assembly 30.9524 4 yes
GO:0051247 positive regulation of protein metabolic process 29.7619 6 yes
GO:0031325 positive regulation of cellular metabolic process 28.5714 5 yes
GO:0009892 negative regulation of metabolic process 27.3810 4 yes
GO:0030030 cell projection organization 27.3810 4 yes
GO:0010647 positive regulation of cell communication 26.1905 5 yes
GO:0023056 positive regulation of signaling 26.1905 4 yes
GO:0033043 regulation of organelle organization 26.1905 5 yes
GO:0051050 positive regulation of transport 26.1905 4 yes
GO:0010941 regulation of cell death 26.1905 4 no
GO:0009889 regulation of biosynthetic process 25.0000 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.0000 5 yes
GO:0031326 regulation of cellular biosynthetic process 25.0000 5 yes
GO:0031399 regulation of protein modification process 25.0000 6 yes
GO:0044087 regulation of cellular component biogenesis 25.0000 4 yes
GO:0048584 positive regulation of response to stimulus 25.0000 4 yes
GO:0007010 cytoskeleton organization 23.8095 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 23.8095 5 yes
GO:0031324 negative regulation of cellular metabolic process 23.8095 5 yes
GO:0031401 positive regulation of protein modification process 23.8095 7 yes
GO:0010556 regulation of macromolecule biosynthetic process 22.6190 5 yes
GO:0019220 regulation of phosphate metabolic process 22.6190 6 yes
GO:0042325 regulation of phosphorylation 22.6190 7 yes
GO:0051174 regulation of phosphorus metabolic process 22.6190 5 yes
GO:0051252 regulation of RNA metabolic process 22.6190 5 yes
GO:0071702 organic substance transport 22.6190 4 yes
GO:0120036 plasma membrane bounded cell projection organization 22.6190 5 yes
GO:0016192 vesicle-mediated transport 22.6190 4 no
GO:0050804 modulation of chemical synaptic transmission 22.6190 5 no
GO:0099177 regulation of trans-synaptic signaling 22.6190 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 21.4286 5 yes
GO:0071705 nitrogen compound transport 21.4286 4 yes
GO:0042981 regulation of apoptotic process 21.4286 6 no
GO:0043067 regulation of programmed cell death 21.4286 5 no
GO:0001932 regulation of protein phosphorylation 20.2381 7 yes
GO:0006355 regulation of DNA-templated transcription 20.2381 6 yes
GO:0009967 positive regulation of signal transduction 20.2381 5 yes
GO:0051726 regulation of cell cycle 20.2381 4 yes
GO:1903506 regulation of nucleic acid-templated transcription 20.2381 7 yes
GO:2001141 regulation of RNA biosynthetic process 20.2381 6 yes
GO:0031344 regulation of cell projection organization 20.2381 5 no
GO:0061024 membrane organization 20.2381 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 20.2381 6 no
GO:0010648 negative regulation of cell communication 20.2381 5 no
GO:0023057 negative regulation of signaling 20.2381 4 no
GO:0009894 regulation of catabolic process 19.0476 4 yes
GO:0010562 positive regulation of phosphorus metabolic process 19.0476 6 yes
GO:0015031 protein transport 19.0476 4 yes
GO:0042327 positive regulation of phosphorylation 19.0476 8 yes
GO:0045937 positive regulation of phosphate metabolic process 19.0476 7 yes
GO:0051129 negative regulation of cellular component organization 19.0476 5 yes
GO:0060627 regulation of vesicle-mediated transport 19.0476 4 yes
GO:0080134 regulation of response to stress 19.0476 4 yes
GO:0099537 trans-synaptic signaling 19.0476 4 yes
GO:0001934 positive regulation of protein phosphorylation 17.8571 8 yes
GO:0007268 chemical synaptic transmission 17.8571 6 yes
GO:0051130 positive regulation of cellular component organization 17.8571 5 yes
GO:0098916 anterograde trans-synaptic signaling 17.8571 5 yes
GO:0045595 regulation of cell differentiation 16.6667 4 yes
GO:0051046 regulation of secretion 16.6667 5 yes
GO:1902533 positive regulation of intracellular signal transduction 16.6667 6 yes
GO:1903530 regulation of secretion by cell 16.6667 4 yes
GO:2000145 regulation of cell motility 16.6667 4 yes
GO:0030334 regulation of cell migration 15.4762 5 yes
GO:0042127 regulation of cell population proliferation 15.4762 4 yes
GO:0044089 positive regulation of cellular component biogenesis 15.4762 5 yes
GO:0051094 positive regulation of developmental process 15.4762 4 yes
GO:0051248 negative regulation of protein metabolic process 14.2857 6 yes
GO:0006886 intracellular protein transport 13.0952 4 yes
GO:0010638 positive regulation of organelle organization 13.0952 6 yes
GO:0030100 regulation of endocytosis 13.0952 5 yes
GO:0030162 regulation of proteolysis 13.0952 6 yes
GO:0042176 regulation of protein catabolic process 13.0952 5 yes
GO:0072657 protein localization to membrane 13.0952 4 yes
GO:1902115 regulation of organelle assembly 13.0952 5 yes
GO:0007264 small GTPase mediated signal transduction 11.9048 4 yes
GO:0009890 negative regulation of biosynthetic process 11.9048 5 yes
GO:0017157 regulation of exocytosis 11.9048 5 yes
GO:0031329 regulation of cellular catabolic process 11.9048 5 yes
GO:0043408 regulation of MAPK cascade 11.9048 6 yes
GO:0045597 positive regulation of cell differentiation 11.9048 5 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 11.9048 6 yes
GO:0051240 positive regulation of multicellular organismal process 11.9048 4 yes
GO:0051253 negative regulation of RNA metabolic process 11.9048 6 yes
GO:0080135 regulation of cellular response to stress 11.9048 4 yes
GO:0006357 regulation of transcription by RNA polymerase II 10.7143 7 yes
GO:0030335 positive regulation of cell migration 10.7143 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 10.7143 6 yes
GO:0040017 positive regulation of locomotion 10.7143 4 yes
GO:0051051 negative regulation of transport 10.7143 4 yes
GO:2000147 positive regulation of cell motility 10.7143 5 yes
GO:0001558 regulation of cell growth 9.5238 4 yes
GO:0007265 Ras protein signal transduction 9.5238 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 9.5238 6 yes
GO:0030031 cell projection assembly 9.5238 5 yes
GO:0045892 negative regulation of DNA-templated transcription 9.5238 7 yes
GO:0051047 positive regulation of secretion 9.5238 5 yes
GO:1902679 negative regulation of RNA biosynthetic process 9.5238 7 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 9.5238 8 yes
GO:1903532 positive regulation of secretion by cell 9.5238 5 yes
GO:0008284 positive regulation of cell population proliferation 8.3333 5 yes
GO:0009895 negative regulation of catabolic process 8.3333 5 yes
GO:0045927 positive regulation of growth 8.3333 4 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 7.1429 8 yes
GO:0031330 negative regulation of cellular catabolic process 7.1429 6 yes
GO:0043410 positive regulation of MAPK cascade 7.1429 7 yes
GO:0045921 positive regulation of exocytosis 7.1429 6 yes
GO:0048259 regulation of receptor-mediated endocytosis 7.1429 6 yes
GO:0090150 establishment of protein localization to membrane 7.1429 4 yes
GO:0120031 plasma membrane bounded cell projection assembly 7.1429 6 yes
GO:1902117 positive regulation of organelle assembly 7.1429 6 yes
GO:0006605 protein targeting 5.9524 5 yes
GO:0030307 positive regulation of cell growth 5.9524 5 yes
GO:0032872 regulation of stress-activated MAPK cascade 5.9524 6 yes
GO:0042177 negative regulation of protein catabolic process 5.9524 6 yes
GO:0045861 negative regulation of proteolysis 5.9524 7 yes
GO:0070302 regulation of stress-activated protein kinase signaling cascade 5.9524 5 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 5.9524 7 yes
GO:0007346 regulation of mitotic cell cycle 4.7619 5 yes
GO:0046328 regulation of JNK cascade 4.7619 7 yes
GO:0061136 regulation of proteasomal protein catabolic process 4.7619 6 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 4.7619 6 yes
GO:0002090 regulation of receptor internalization 3.5714 7 yes
GO:0006612 protein targeting to membrane 3.5714 5 yes
GO:0010717 regulation of epithelial to mesenchymal transition 3.5714 5 yes
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3.5714 6 yes
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 3.5714 7 yes
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 3.5714 8 yes
GO:0032874 positive regulation of stress-activated MAPK cascade 3.5714 7 yes
GO:0045806 negative regulation of endocytosis 3.5714 5 yes
GO:0046330 positive regulation of JNK cascade 3.5714 8 yes
GO:0048261 negative regulation of receptor-mediated endocytosis 3.5714 6 yes
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3.5714 6 yes
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3.5714 5 yes
GO:0090287 regulation of cellular response to growth factor stimulus 3.5714 4 yes
GO:1901799 negative regulation of proteasomal protein catabolic process 3.5714 7 yes
GO:1903051 negative regulation of proteolysis involved in protein catabolic process 3.5714 8 yes
GO:1903541 regulation of exosomal secretion 3.5714 6 yes
GO:1903543 positive regulation of exosomal secretion 3.5714 6 yes
GO:1903551 regulation of extracellular exosome assembly 3.5714 6 yes
GO:1903553 positive regulation of extracellular exosome assembly 3.5714 7 yes
GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 3.5714 5 yes
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 3.5714 7 yes
GO:0002091 negative regulation of receptor internalization 2.3810 7 yes
GO:0006930 substrate-dependent cell migration, cell extension 2.3810 7 yes
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.3810 5 yes
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 2.3810 7 yes
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 2.3810 6 yes
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 2.3810 8 yes
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.3810 6 yes
GO:0099054 presynapse assembly 2.3810 5 yes
GO:0099172 presynapse organization 2.3810 4 yes
GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 2.3810 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in SDCB1_HUMAN
DOID:0050700 cardiomyopathy 4.7619 4 no
DOID:0060036 intrinsic cardiomyopathy 4.7619 5 no
DOID:114 heart disease 4.7619 3 no
DOID:2843 long QT syndrome 3.5714 6 no
DOID:10273 heart conduction disease 2.3810 4 no
DOID:0060038 specific developmental disorder 2.3810 3 no
DOID:1059 intellectual disability 2.3810 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NECT1_HUMAN [view interactions] Low throughput no yes
EPHA7_HUMAN [view entry] [view interactions] Low throughput yes no
EFNB1_HUMAN [view interactions] Low throughput no yes
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
TGFA_HUMAN [view interactions] Low throughput no yes
JAG1_HUMAN [view interactions] Low throughput no no
SOX4_HUMAN [view interactions] Low throughput no yes
FZD7_HUMAN [view interactions] Low throughput no yes
FZD3_HUMAN [view interactions] Low throughput no yes
FZD8_HUMAN [view interactions] Low throughput no yes
SDC2_HUMAN [view interactions] Low throughput no yes
CD6_HUMAN [view interactions] Low throughput no no
EFNB3_HUMAN [view entry] [view interactions] Low throughput yes yes
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
SDC4_HUMAN [view interactions] Low throughput no yes
GRIK2_HUMAN [view entry] [view interactions] Low throughput yes yes
IL5RA_HUMAN [view interactions] Low throughput no no
GRIK1_HUMAN [view entry] [view interactions] Low throughput yes yes
ULK1_HUMAN [view interactions] Low throughput no no
RAB5A_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRJ_HUMAN [view interactions] Low throughput no yes
MERL_HUMAN [view interactions] Low throughput no yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
GPR37_HUMAN [view interactions] Low throughput no no
PTN1_HUMAN [view interactions] Low throughput no yes
SDC1_HUMAN [view interactions] Low throughput no no
TRAF6_HUMAN [view interactions] Low throughput no yes
ILK_HUMAN [view interactions] Low throughput no no
CD63_HUMAN [view interactions] Low throughput no no
SDCB1_HUMAN [view entry] [view interactions] Low throughput yes yes
SEPT1_HUMAN [view interactions] High throughput no no
TMCO2_HUMAN [view interactions] High throughput no no
TCF21_HUMAN [view interactions] High throughput no yes
MYLIP_HUMAN [view interactions] High throughput no no
KCNV1_HUMAN [view interactions] High throughput no no
KTBL1_HUMAN [view interactions] High throughput no no
RRS1_HUMAN [view interactions] High throughput no yes
BRNP2_HUMAN [view interactions] High throughput no no
GKAP1_HUMAN [view interactions] High throughput no no
EGLN1_HUMAN [view entry] [view interactions] High throughput yes yes
GRCR1_HUMAN [view interactions] High throughput no no
SP8_HUMAN [view interactions] High throughput no no
TCP4_HUMAN [view interactions] High throughput no yes
SMCA2_HUMAN [view interactions] High throughput no yes
ID3_HUMAN [view interactions] High throughput no yes
IFNL3_HUMAN [view interactions] High throughput no no
SYPL1_HUMAN [view interactions] High throughput no yes
TBC3H_HUMAN [view interactions] High throughput no no
EMIL3_HUMAN [view interactions] High throughput no yes
ABCB6_HUMAN [view interactions] High throughput no yes
C2C2L_HUMAN [view interactions] High throughput no yes
AFF4_HUMAN [view interactions] High throughput no yes
HUS1_HUMAN [view interactions] High throughput no yes
HDAC7_HUMAN [view interactions] High throughput no no
HHAT_HUMAN [view interactions] High throughput no yes
OTUB2_HUMAN [view interactions] High throughput no no
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
G3ST1_HUMAN [view interactions] High throughput no no
K1C14_HUMAN [view interactions] High throughput no no
NECT3_HUMAN [view entry] [view interactions] High throughput yes yes
LERL1_HUMAN [view interactions] High throughput no no
PP6R2_HUMAN [view interactions] High throughput no no
N4BP3_HUMAN [view interactions] High throughput no yes
ZN768_HUMAN [view interactions] High throughput no yes
SNRPA_HUMAN [view interactions] High throughput no yes
ZEP1_HUMAN [view interactions] High throughput no yes
RS26_HUMAN [view entry] [view interactions] High throughput yes yes
ODAM_HUMAN [view interactions] High throughput no no
RPRM_HUMAN [view interactions] High throughput no no
RTL8B_HUMAN [view interactions] High throughput no no
MKRN1_HUMAN [view interactions] High throughput no no
AIM2_HUMAN [view interactions] High throughput no no
PDZ1I_HUMAN [view interactions] High throughput no no
CNOT1_HUMAN [view interactions] High throughput no yes
SFT2A_HUMAN [view interactions] High throughput no no
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
DERL3_HUMAN [view interactions] High throughput no yes
TMED2_HUMAN [view interactions] High throughput no yes
CAV2_HUMAN [view interactions] High throughput no no
JUNB_HUMAN [view interactions] High throughput no yes
SYS1_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
SDCG8_HUMAN [view interactions] High throughput no yes
TFP11_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
FRIH_HUMAN [view entry] [view interactions] High throughput yes yes
RIC8A_HUMAN [view entry] [view interactions] High throughput yes no
WFS1_HUMAN [view entry] [view interactions] High throughput yes yes
VAPB_HUMAN [view entry] [view interactions] High throughput yes yes
RNF11_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
SPRE1_HUMAN [view interactions] High throughput no yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
GRIA3_HUMAN [view entry] [view interactions] High throughput yes yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
GRIA4_HUMAN [view entry] [view interactions] High throughput yes no
ATX1_HUMAN [view interactions] High throughput no yes
GRM4_HUMAN [view interactions] High throughput no no
WDR91_HUMAN [view entry] [view interactions] High throughput yes no
GRM7_HUMAN [view entry] [view interactions] High throughput yes no
ESR1_HUMAN [view interactions] High throughput no no
GRIA2_HUMAN [view entry] [view interactions] High throughput yes yes
S15A4_HUMAN [view interactions] High throughput no yes
GRM6_HUMAN [view interactions] High throughput no no
MYPC2_HUMAN [view interactions] High throughput no no
GRM3_HUMAN [view entry] [view interactions] High throughput yes no
FYN_HUMAN [view entry] [view interactions] High throughput yes no
GRIA1_HUMAN [view entry] [view interactions] High throughput yes yes
CD3D_HUMAN [view interactions] High throughput no no
SCLT1_HUMAN [view interactions] High throughput no yes
HSC20_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
H2B1C_HUMAN [view interactions] High throughput no yes
C102B_HUMAN [view interactions] High throughput no yes
TRI38_HUMAN [view interactions] High throughput no yes
TRAF5_HUMAN [view interactions] High throughput no yes
WASL_HUMAN [view entry] [view interactions] High throughput yes yes
CEP55_HUMAN [view interactions] High throughput no yes
ERIC2_HUMAN [view interactions] High throughput no no
HSBP1_HUMAN [view interactions] High throughput no no
RTN1_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT14_HUMAN [view interactions] High throughput no yes
CAPS1_HUMAN [view entry] [view interactions] High throughput yes yes
SSNA1_HUMAN [view interactions] High throughput no no
ENTR1_HUMAN [view interactions] High throughput no no
ST1B1_HUMAN [view interactions] High throughput no no
TRIM1_HUMAN [view interactions] High throughput no no
PPIP1_HUMAN [view interactions] High throughput no no
GNMT_HUMAN [view interactions] High throughput no no
FOXP2_HUMAN [view interactions] High throughput no yes
NECA2_HUMAN [view interactions] High throughput no yes
CDIPT_HUMAN [view entry] [view interactions] High throughput yes yes
PR40A_HUMAN [view interactions] High throughput no yes
FRIL_HUMAN [view interactions] High throughput no yes
HOMEZ_HUMAN [view interactions] High throughput no no
CRYAA_HUMAN [view interactions] High throughput no no
KR103_HUMAN [view interactions] High throughput no no
HPRT_HUMAN [view interactions] High throughput no yes
CBY2_HUMAN [view interactions] High throughput no no
LDOC1_HUMAN [view interactions] High throughput no no
NADK_HUMAN [view interactions] High throughput no yes
SCML1_HUMAN [view interactions] High throughput no no
KCNH1_HUMAN [view entry] [view interactions] High throughput yes yes
MGLL_HUMAN [view interactions] High throughput no yes
KLHL2_HUMAN [view interactions] High throughput no no
SNG1_HUMAN [view entry] [view interactions] High throughput yes yes
DCTD_HUMAN [view interactions] High throughput no yes
GSG1_HUMAN [view interactions] High throughput no no
CDD_HUMAN [view interactions] High throughput no no
MATN4_HUMAN [view interactions] High throughput no no
KRA59_HUMAN [view interactions] High throughput no no
RALY_HUMAN [view interactions] High throughput no yes
TRI27_HUMAN [view interactions] High throughput no yes
CEP85_HUMAN [view interactions] High throughput no no
HNRPC_HUMAN [view interactions] High throughput no yes
RPR1A_HUMAN [view interactions] High throughput no yes
HXA1_HUMAN [view interactions] High throughput no no
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
T23O_HUMAN [view interactions] High throughput no no
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
SRS11_HUMAN [view interactions] High throughput no yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
REL_HUMAN [view interactions] High throughput no yes
PDE9A_HUMAN [view interactions] High throughput no yes
PTPS_HUMAN [view interactions] High throughput no yes
BEND7_HUMAN [view interactions] High throughput no no
KR107_HUMAN [view interactions] High throughput no no
MOBP_HUMAN [view interactions] High throughput no no
5NTC_HUMAN [view interactions] High throughput no yes
CTBP2_HUMAN [view interactions] High throughput no no
IKZF1_HUMAN [view interactions] High throughput no no
WASH1_HUMAN [view interactions] High throughput no yes
CACO2_HUMAN [view interactions] High throughput no yes
TARG1_HUMAN [view interactions] High throughput no no
TRI32_HUMAN [view entry] [view interactions] High throughput yes yes
PPARA_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
CYHR1_HUMAN [view interactions] High throughput no yes
TLE5_HUMAN [view interactions] High throughput no no
ITF2_HUMAN [view interactions] High throughput no yes
P5CR3_HUMAN [view interactions] High throughput no no
AN36B_HUMAN [view interactions] High throughput no no
KLH12_HUMAN [view interactions] High throughput no no
SRSF7_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
RBM39_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
ANR40_HUMAN [view interactions] High throughput no yes
TSN3_HUMAN [view interactions] High throughput no yes
KHDR2_HUMAN [view interactions] High throughput no yes
SYRC_HUMAN [view interactions] High throughput no yes
MYOME_HUMAN [view interactions] High throughput no no
SYIC_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
SYQ_HUMAN [view interactions] High throughput no yes
RUN3A_HUMAN [view interactions] High throughput no yes
SYEP_HUMAN [view interactions] High throughput no yes
NT2NA_HUMAN [view interactions] High throughput no no
AIMP2_HUMAN [view interactions] High throughput no yes
KCTD9_HUMAN [view interactions] High throughput no no
SYDC_HUMAN [view interactions] High throughput no yes
KCTD1_HUMAN [view interactions] High throughput no no
SYMC_HUMAN [view interactions] High throughput no yes
NKAP1_HUMAN [view interactions] High throughput no yes
SYTC2_HUMAN [view interactions] High throughput no yes
FAM9B_HUMAN [view interactions] High throughput no no
AIMP1_HUMAN [view interactions] High throughput no yes
IHO1_HUMAN [view interactions] High throughput no no
MCA3_HUMAN [view interactions] High throughput no yes
PHC2_HUMAN [view interactions] High throughput no yes
SYLC_HUMAN [view interactions] High throughput no yes
SIAH1_HUMAN [view interactions] High throughput no yes
ANR28_HUMAN [view interactions] High throughput no no
FAD1_HUMAN [view interactions] High throughput no yes
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
PNMA1_HUMAN [view interactions] High throughput no yes
TNR3_HUMAN [view interactions] High throughput no yes
KCTD6_HUMAN [view interactions] High throughput no yes
WRP73_HUMAN [view interactions] High throughput no no
IN80E_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
ZBT8A_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
TEKT1_HUMAN [view interactions] High throughput no no
SAMD1_HUMAN [view interactions] High throughput no no
EDAD_HUMAN [view entry] [view interactions] High throughput yes yes
MANS1_HUMAN [view interactions] High throughput no yes
TM239_HUMAN [view interactions] High throughput no no
GPC5B_HUMAN [view entry] [view interactions] High throughput yes no
ENOX1_HUMAN [view interactions] High throughput no no
PCDBB_HUMAN [view interactions] High throughput no no
MTNB_HUMAN [view interactions] High throughput no yes
PCDGG_HUMAN [view interactions] High throughput no no
DTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
FA8A1_HUMAN [view interactions] High throughput no yes
CKLF5_HUMAN [view interactions] High throughput no yes
PCDGD_HUMAN [view interactions] High throughput no no
TIFA_HUMAN [view interactions] High throughput no yes
RUSF1_HUMAN [view interactions] High throughput no yes
NO40_HUMAN [view interactions] High throughput no yes
TR10A_HUMAN [view interactions] High throughput no no
ROP1A_HUMAN [view interactions] High throughput no no
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
DCTP1_HUMAN [view interactions] High throughput no no
LITAF_HUMAN [view interactions] High throughput no yes
TRI54_HUMAN [view interactions] High throughput no no
TM223_HUMAN [view interactions] High throughput no yes
F118B_HUMAN [view interactions] High throughput no yes
TEDC2_HUMAN [view interactions] High throughput no no
MR1L1_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
REEP6_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
ABI2_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
THG1_HUMAN [view interactions] High throughput no yes
CGAS_HUMAN [view interactions] High throughput no yes
F118A_HUMAN [view interactions] High throughput no yes
CUTC_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
LZTL1_HUMAN [view interactions] High throughput no no
DYR1A_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
ZBT7B_HUMAN [view interactions] High throughput no no
PUF60_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
SEPT3_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
CGBP1_HUMAN [view interactions] High throughput no yes
NUPR1_HUMAN [view interactions] High throughput no no
NAGK_HUMAN [view interactions] High throughput no no
NPC1_HUMAN [view interactions] High throughput no yes
WASC3_HUMAN [view interactions] High throughput no yes
CTIP_HUMAN [view interactions] High throughput no no
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
UFL1_HUMAN [view interactions] High throughput no yes
PNMA2_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
HMGB3_HUMAN [view interactions] High throughput no no
PCDG7_HUMAN [view interactions] High throughput no no
TFIP8_HUMAN [view interactions] High throughput no no
SYK_HUMAN [view interactions] High throughput no yes
MBD3_HUMAN [view interactions] High throughput no yes
INGR1_HUMAN [view interactions] High throughput no no
LEG2_HUMAN [view interactions] High throughput no no
EDAR_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
RN149_HUMAN [view interactions] High throughput no no
RINI_HUMAN [view interactions] High throughput no yes
FFAR1_HUMAN [view interactions] High throughput no no
UB2R1_HUMAN [view interactions] High throughput no yes
LEG1_HUMAN [view interactions] High throughput no yes
UBE2A_HUMAN [view interactions] High throughput no no
HBB_HUMAN [view interactions] High throughput no no
CLK2_HUMAN [view interactions] High throughput no yes
HBA_HUMAN [view interactions] High throughput no no
CLK3_HUMAN [view interactions] High throughput no yes
HBD_HUMAN [view interactions] High throughput no no
LSM6_HUMAN [view interactions] High throughput no yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
PRS10_HUMAN [view interactions] High throughput no yes
INKA1_HUMAN [view interactions] High throughput no no
SET_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
MD2L1_HUMAN [view interactions] High throughput no no
IFM3_HUMAN [view interactions] High throughput no yes
DMC1_HUMAN [view interactions] High throughput no no
TM192_HUMAN [view interactions] High throughput no yes
TKFC_HUMAN [view interactions] High throughput no no
PDE2A_HUMAN [view entry] [view interactions] High throughput yes yes
B2L15_HUMAN [view interactions] High throughput no no
LEG3_HUMAN [view interactions] High throughput no yes
CT455_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
CT45A_HUMAN [view interactions] High throughput no no
RHOJ_HUMAN [view interactions] High throughput no yes
GPT11_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
EIF1A_HUMAN [view interactions] High throughput no no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
SR1IP_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
PR38A_HUMAN [view interactions] High throughput no no
RHOH_HUMAN [view interactions] High throughput no yes
CT453_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
ZCH10_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
AN32B_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
OSTF1_HUMAN [view interactions] High throughput no yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
EAF1_HUMAN [view interactions] High throughput no yes
RHOC_HUMAN [view interactions] High throughput no no
IF5A2_HUMAN [view interactions] High throughput no yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
CK068_HUMAN [view interactions] High throughput no yes
GRM2_HUMAN [view entry] [view interactions] High throughput yes yes
CDCP1_HUMAN [view interactions] High throughput no yes
CA109_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
PRR13_HUMAN [view interactions] High throughput no yes
CADM1_HUMAN [view entry] [view interactions] High throughput yes no
MMTA2_HUMAN [view interactions] High throughput no yes
SPCS_HUMAN [view interactions] High throughput no no
TNKS1_HUMAN [view interactions] High throughput no yes
SNP25_HUMAN [view entry] [view interactions] High throughput yes yes
SCG3_HUMAN [view interactions] High throughput no yes
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
SYHM_HUMAN [view entry] [view interactions] High throughput yes yes
HSF2B_HUMAN [view interactions] High throughput no yes
VAMP2_HUMAN [view entry] [view interactions] High throughput yes no
PHS_HUMAN [view interactions] High throughput no yes
SYNM_HUMAN [view interactions] High throughput no yes
AR6P1_HUMAN [view interactions] High throughput no yes
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
SRSF3_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
UB2R2_HUMAN [view interactions] High throughput no no
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
HOME3_HUMAN [view entry] [view interactions] High throughput yes yes
ACTC_HUMAN [view interactions] High throughput no no
DYLT1_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
CDN2D_HUMAN [view interactions] High throughput no no
PERI_HUMAN [view entry] [view interactions] High throughput yes no
TSN_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
LDHB_HUMAN [view entry] [view interactions] High throughput yes yes
SQSTM_HUMAN [view interactions] High throughput no yes
MEOX1_HUMAN [view interactions] High throughput no no
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
ONCO_HUMAN [view interactions] High throughput no no
S100B_HUMAN [view entry] [view interactions] High throughput yes yes
CABP5_HUMAN [view interactions] High throughput no no
UBB_HUMAN [view entry] [view interactions] High throughput yes yes
PCH2_HUMAN [view interactions] High throughput no no
CRX_HUMAN [view interactions] High throughput no no
MINY3_HUMAN [view interactions] High throughput no yes
KRA13_HUMAN [view interactions] High throughput no no
HEXI2_HUMAN [view interactions] High throughput no yes
SRCRL_HUMAN [view interactions] High throughput no yes
SPXN3_HUMAN [view interactions] High throughput no no
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
RL22_HUMAN [view entry] [view interactions] High throughput yes no
IF5A1_HUMAN [view interactions] High throughput no yes
TP8L3_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
PCY1A_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
UBE2K_HUMAN [view interactions] High throughput no yes
FHL5_HUMAN [view interactions] High throughput no no
HXA7_HUMAN [view interactions] High throughput no no
SNAB_HUMAN [view entry] [view interactions] High throughput yes yes
RP9_HUMAN [view interactions] High throughput no yes
FADD_HUMAN [view interactions] High throughput no yes
MK09_HUMAN [view interactions] High throughput no yes
HMBX1_HUMAN [view interactions] High throughput no yes
NC2A_HUMAN [view interactions] High throughput no yes
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CT451_HUMAN [view interactions] High throughput no no
GGPPS_HUMAN [view interactions] High throughput no yes
ZSC23_HUMAN [view interactions] High throughput no no
SWET1_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
GSC2_HUMAN [view interactions] High throughput no no
ZN343_HUMAN [view interactions] High throughput no yes
FAM9A_HUMAN [view interactions] High throughput no no
MOFA1_HUMAN [view interactions] High throughput no yes
RPIA_HUMAN [view interactions] High throughput no yes
ZMY12_HUMAN [view interactions] High throughput no no
ARFP2_HUMAN [view interactions] High throughput no no
ZN660_HUMAN [view interactions] High throughput no no
TMM17_HUMAN [view interactions] High throughput no yes
CC106_HUMAN [view interactions] High throughput no no
PDLI4_HUMAN [view entry] [view interactions] High throughput yes yes
IBP6_HUMAN [view interactions] High throughput no yes
FHL3_HUMAN [view interactions] High throughput no no
PANKY_HUMAN [view interactions] High throughput no no
RIR2_HUMAN [view interactions] High throughput no no
CHM1A_HUMAN [view entry] [view interactions] High throughput yes no
CBR3_HUMAN [view entry] [view interactions] High throughput yes yes
LUR1L_HUMAN [view interactions] High throughput no no
RPC10_HUMAN [view interactions] High throughput no yes
CTDS1_HUMAN [view interactions] High throughput no no
GET4_HUMAN [view interactions] High throughput no yes
PFD5_HUMAN [view interactions] High throughput no yes
KRA15_HUMAN [view interactions] High throughput no no
PIHD2_HUMAN [view interactions] High throughput no no
LDB2_HUMAN [view interactions] High throughput no yes
PSME2_HUMAN [view interactions] High throughput no no
ZN485_HUMAN [view interactions] High throughput no no
PSB3_HUMAN [view interactions] High throughput no yes
EXOS4_HUMAN [view interactions] High throughput no yes
PHF11_HUMAN [view interactions] High throughput no no
RPB11_HUMAN [view interactions] High throughput no no
YIF1A_HUMAN [view interactions] High throughput no yes
CHIC2_HUMAN [view interactions] High throughput no no
CD166_HUMAN [view interactions] Computational no no
SC6A5_HUMAN [view interactions] Computational no no
EZRI_HUMAN [view entry] [view interactions] Computational yes no
RHEB_HUMAN [view entry] [view interactions] Computational yes yes
DEN2B_HUMAN [view interactions] Computational no yes
CD4_HUMAN [view interactions] Computational no no
IL5_HUMAN [view interactions] Computational no no
NFASC_HUMAN [view entry] [view interactions] Computational yes yes