WASL_HUMAN
Evidence for PS localization
Functions
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization (PubMed, PubMed, PubMed, PubMed, PubMed). Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia (PubMed). In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization (PubMed). Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression . Plays a role in dendrite spine morphogenesis . Decreasing levels of DNMBP (using antisense RNA) alters apical junction morphology in cultured enterocytes, junctions curve instead of being nearly linear (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
No data found.
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI003346 | LIG_GBD_Chelix_1 | LIG | 467 | 475 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in WASL_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 37.8378 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 31.0811 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 29.7297 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.7297 | 4 | no |
| GO:0019900 | kinase binding | 27.0270 | 4 | no |
| GO:0019901 | protein kinase binding | 24.3243 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 21.6216 | 5 | no |
| GO:0045296 | cadherin binding | 21.6216 | 4 | no |
| GO:0005524 | ATP binding | 20.2703 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.2703 | 5 | no |
| GO:0030695 | GTPase regulator activity | 12.1622 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in WASL_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 77.0270 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 71.6216 | 4 | yes |
| GO:0022607 | cellular component assembly | 52.7027 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 52.7027 | 4 | yes |
| GO:0030030 | cell projection organization | 51.3514 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 51.3514 | 5 | yes |
| GO:0051130 | positive regulation of cellular component organization | 50.0000 | 5 | yes |
| GO:0006996 | organelle organization | 48.6486 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 48.6486 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 45.9459 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 45.9459 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 44.5946 | 4 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 44.5946 | 6 | yes |
| GO:0080090 | regulation of primary metabolic process | 44.5946 | 4 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 43.2432 | 5 | yes |
| GO:0032970 | regulation of actin filament-based process | 43.2432 | 4 | yes |
| GO:0010646 | regulation of cell communication | 43.2432 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.5405 | 4 | yes |
| GO:0097435 | supramolecular fiber organization | 40.5405 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 40.5405 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 39.1892 | 5 | yes |
| GO:0007010 | cytoskeleton organization | 39.1892 | 5 | no |
| GO:0007015 | actin filament organization | 37.8378 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.8378 | 5 | yes |
| GO:0031344 | regulation of cell projection organization | 37.8378 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 37.8378 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 37.8378 | 6 | yes |
| GO:1902903 | regulation of supramolecular fiber organization | 37.8378 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 37.8378 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.4865 | 5 | yes |
| GO:0110053 | regulation of actin filament organization | 36.4865 | 6 | yes |
| GO:0016192 | vesicle-mediated transport | 36.4865 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.1351 | 5 | yes |
| GO:0051049 | regulation of transport | 35.1351 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.1351 | 5 | yes |
| GO:0010647 | positive regulation of cell communication | 33.7838 | 5 | no |
| GO:0023056 | positive regulation of signaling | 33.7838 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 32.4324 | 6 | yes |
| GO:0032990 | cell part morphogenesis | 32.4324 | 4 | yes |
| GO:0048858 | cell projection morphogenesis | 32.4324 | 5 | yes |
| GO:0006897 | endocytosis | 32.4324 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 32.4324 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 32.4324 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 32.4324 | 5 | no |
| GO:0031346 | positive regulation of cell projection organization | 31.0811 | 6 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 31.0811 | 6 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 31.0811 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 31.0811 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 31.0811 | 4 | no |
| GO:0043933 | protein-containing complex organization | 29.7297 | 4 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 29.7297 | 7 | yes |
| GO:1902905 | positive regulation of supramolecular fiber organization | 29.7297 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 29.7297 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 28.3784 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 28.3784 | 5 | yes |
| GO:0048812 | neuron projection morphogenesis | 28.3784 | 7 | yes |
| GO:0065003 | protein-containing complex assembly | 28.3784 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 27.0270 | 5 | yes |
| GO:0051050 | positive regulation of transport | 27.0270 | 4 | yes |
| GO:0032271 | regulation of protein polymerization | 27.0270 | 6 | no |
| GO:0032535 | regulation of cellular component size | 27.0270 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 27.0270 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 27.0270 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.0270 | 5 | no |
| GO:0071310 | cellular response to organic substance | 27.0270 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 27.0270 | 4 | no |
| GO:0022604 | regulation of cell morphogenesis | 27.0270 | 5 | no |
| GO:0030334 | regulation of cell migration | 25.6757 | 5 | yes |
| GO:2000145 | regulation of cell motility | 25.6757 | 4 | yes |
| GO:0010941 | regulation of cell death | 25.6757 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 25.6757 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.6757 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.3243 | 5 | yes |
| GO:0032880 | regulation of protein localization | 24.3243 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 24.3243 | 4 | yes |
| GO:0060491 | regulation of cell projection assembly | 24.3243 | 5 | yes |
| GO:0008064 | regulation of actin polymerization or depolymerization | 24.3243 | 6 | no |
| GO:0030832 | regulation of actin filament length | 24.3243 | 5 | no |
| GO:0030833 | regulation of actin filament polymerization | 24.3243 | 7 | no |
| GO:0031399 | regulation of protein modification process | 24.3243 | 6 | no |
| GO:0030031 | cell projection assembly | 24.3243 | 5 | no |
| GO:0080134 | regulation of response to stress | 24.3243 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.9730 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 22.9730 | 6 | yes |
| GO:0001932 | regulation of protein phosphorylation | 22.9730 | 7 | no |
| GO:0008104 | protein localization | 22.9730 | 4 | no |
| GO:0034330 | cell junction organization | 22.9730 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.9730 | 6 | no |
| GO:0042327 | positive regulation of phosphorylation | 22.9730 | 8 | no |
| GO:0042981 | regulation of apoptotic process | 22.9730 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 22.9730 | 5 | no |
| GO:0045597 | positive regulation of cell differentiation | 22.9730 | 5 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.9730 | 7 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 22.9730 | 4 | no |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 22.9730 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 22.9730 | 6 | no |
| GO:0043085 | positive regulation of catalytic activity | 22.9730 | 4 | no |
| GO:0061024 | membrane organization | 21.6216 | 4 | yes |
| GO:0007264 | small GTPase mediated signal transduction | 21.6216 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 20.2703 | 6 | yes |
| GO:0051252 | regulation of RNA metabolic process | 20.2703 | 5 | yes |
| GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 20.2703 | 6 | yes |
| GO:0002684 | positive regulation of immune system process | 20.2703 | 4 | no |
| GO:0030335 | positive regulation of cell migration | 20.2703 | 6 | no |
| GO:0040017 | positive regulation of locomotion | 20.2703 | 4 | no |
| GO:2000147 | positive regulation of cell motility | 20.2703 | 5 | no |
| GO:0060284 | regulation of cell development | 20.2703 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 18.9189 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 18.9189 | 5 | yes |
| GO:0031175 | neuron projection development | 18.9189 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 18.9189 | 6 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 18.9189 | 4 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 18.9189 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 18.9189 | 6 | yes |
| GO:0008154 | actin polymerization or depolymerization | 17.5676 | 6 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 17.5676 | 6 | yes |
| GO:0030100 | regulation of endocytosis | 16.2162 | 5 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 14.8649 | 7 | yes |
| GO:0030041 | actin filament polymerization | 13.5135 | 7 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 13.5135 | 7 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 13.5135 | 6 | yes |
| GO:0051258 | protein polymerization | 13.5135 | 6 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 13.5135 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 13.5135 | 8 | yes |
| GO:0051125 | regulation of actin nucleation | 12.1622 | 7 | yes |
| GO:0051127 | positive regulation of actin nucleation | 12.1622 | 7 | yes |
| GO:0002685 | regulation of leukocyte migration | 10.8108 | 4 | yes |
| GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation | 10.8108 | 8 | yes |
| GO:0106027 | neuron projection organization | 10.8108 | 6 | yes |
| GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation | 10.8108 | 8 | yes |
| GO:0045807 | positive regulation of endocytosis | 9.4595 | 5 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 9.4595 | 8 | yes |
| GO:0097061 | dendritic spine organization | 9.4595 | 5 | yes |
| GO:0099173 | postsynapse organization | 9.4595 | 4 | yes |
| GO:0002683 | negative regulation of immune system process | 8.1081 | 4 | yes |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 8.1081 | 4 | yes |
| GO:0040013 | negative regulation of locomotion | 8.1081 | 4 | yes |
| GO:0048259 | regulation of receptor-mediated endocytosis | 8.1081 | 6 | yes |
| GO:2000146 | negative regulation of cell motility | 8.1081 | 5 | yes |
| GO:0030336 | negative regulation of cell migration | 6.7568 | 6 | yes |
| GO:0071675 | regulation of mononuclear cell migration | 6.7568 | 5 | yes |
| GO:0048260 | positive regulation of receptor-mediated endocytosis | 5.4054 | 6 | yes |
| GO:0051489 | regulation of filopodium assembly | 5.4054 | 7 | yes |
| GO:0051650 | establishment of vesicle localization | 5.4054 | 4 | yes |
| GO:0060997 | dendritic spine morphogenesis | 5.4054 | 6 | yes |
| GO:1903729 | regulation of plasma membrane organization | 5.4054 | 5 | yes |
| GO:2000401 | regulation of lymphocyte migration | 5.4054 | 6 | yes |
| GO:0030050 | vesicle transport along actin filament | 4.0541 | 4 | yes |
| GO:0051491 | positive regulation of filopodium assembly | 4.0541 | 7 | yes |
| GO:0099515 | actin filament-based transport | 4.0541 | 5 | yes |
| GO:0099518 | vesicle cytoskeletal trafficking | 4.0541 | 5 | yes |
| GO:1903525 | regulation of membrane tubulation | 4.0541 | 6 | yes |
| GO:1903526 | negative regulation of membrane tubulation | 4.0541 | 6 | yes |
| GO:2000369 | regulation of clathrin-dependent endocytosis | 4.0541 | 7 | yes |
| GO:2000370 | positive regulation of clathrin-dependent endocytosis | 4.0541 | 7 | yes |
| GO:0002686 | negative regulation of leukocyte migration | 2.7027 | 5 | yes |
| GO:0006900 | vesicle budding from membrane | 2.7027 | 5 | yes |
| GO:0016050 | vesicle organization | 2.7027 | 5 | yes |
| GO:0071676 | negative regulation of mononuclear cell migration | 2.7027 | 6 | yes |
| GO:2000402 | negative regulation of lymphocyte migration | 2.7027 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in WASL_HUMAN |
|---|---|---|---|---|
| DOID:0111962 | combined immunodeficiency | 2.7027 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 2.7027 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ACTG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PR40A_HUMAN | [view interactions] | Low throughput | no | yes |
| PACN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VIPR1_HUMAN | [view interactions] | Low throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBP1L_HUMAN | [view interactions] | Low throughput | no | yes |
| PPIP1_HUMAN | [view interactions] | Low throughput | no | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GELS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARPC5_HUMAN | [view interactions] | Low throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
| CIB1_HUMAN | [view interactions] | Low throughput | no | no |
| WIPF1_HUMAN | [view interactions] | Low throughput | no | no |
| ROBO4_HUMAN | [view interactions] | Low throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FNBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NOSTN_HUMAN | [view interactions] | Low throughput | no | yes |
| SNX9_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PAK4_HUMAN | [view interactions] | Low throughput | no | yes |
| SPN90_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CRK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARC1B_HUMAN | [view interactions] | Low throughput | no | no |
| WASL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PROF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PROF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CIP4_HUMAN | [view interactions] | Low throughput | no | no |
| ITA2_HUMAN | [view interactions] | Low throughput | no | yes |
| CD44_HUMAN | [view interactions] | Low throughput | no | yes |
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PGFRB_HUMAN | [view interactions] | Low throughput | no | yes |
| COBL_HUMAN | [view interactions] | Low throughput | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DNMBP_HUMAN | [view interactions] | Low throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARPC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BI2L1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN2_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOQ_HUMAN | [view interactions] | Low throughput | no | no |
| VINEX_HUMAN | [view interactions] | Low throughput | no | no |
| BIN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CORO7_HUMAN | [view interactions] | Low throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDIA1_HUMAN | [view interactions] | High throughput | no | yes |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LSM1_HUMAN | [view interactions] | High throughput | no | no |
| ZN638_HUMAN | [view interactions] | High throughput | no | yes |
| WASF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| BICD2_HUMAN | [view interactions] | High throughput | no | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FIBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF8_HUMAN | [view interactions] | High throughput | no | yes |
| HPT_HUMAN | [view interactions] | High throughput | no | no |
| IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FCSD2_HUMAN | [view interactions] | High throughput | no | no |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN395_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| KI18A_HUMAN | [view interactions] | High throughput | no | yes |
| CHMP6_HUMAN | [view interactions] | High throughput | no | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| CHLE_HUMAN | [view interactions] | High throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG4C_HUMAN | [view interactions] | High throughput | no | yes |
| WIPF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTBL_HUMAN | [view interactions] | High throughput | no | no |
| ACY2_HUMAN | [view interactions] | High throughput | no | no |
| WIPF3_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| SDCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTK6_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3B_HUMAN | [view interactions] | High throughput | no | yes |
| PACN3_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| ITBP2_HUMAN | [view interactions] | High throughput | no | no |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| TNNT3_HUMAN | [view interactions] | High throughput | no | no |
| WWP1_HUMAN | [view interactions] | High throughput | no | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM2_HUMAN | [view interactions] | High throughput | no | yes |
| OSTF1_HUMAN | [view interactions] | High throughput | no | yes |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3R1_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBS3A_HUMAN | [view interactions] | High throughput | no | no |
| RHG12_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| ARGAL_HUMAN | [view interactions] | High throughput | no | yes |
| MET_HUMAN | [view interactions] | Computational | no | yes |
| KIRR1_HUMAN | [view interactions] | Computational | no | no |
| GAB1_HUMAN | [view interactions] | Computational | no | yes |
| GAS7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARP5L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FCSD1_HUMAN | [view interactions] | Computational | no | yes |
| COF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AMPH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARP3B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NONO_HUMAN | [view interactions] | Computational | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BTK_HUMAN | [view interactions] | Computational | no | no |
| BRK1_HUMAN | [view interactions] | Computational | no | no |
| PODO_HUMAN | [view interactions] | Computational | no | no |
| HGF_HUMAN | [view interactions] | Computational | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DBNL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MYO1E_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EFNB3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAV1_HUMAN | [view interactions] | Computational | no | no |
| ARP3C_HUMAN | [view interactions] | Computational | no | no |
| ARC1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SPD2A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ACTS_HUMAN | [view interactions] | Computational | no | no |
| CYFP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NCKPL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PDGFB_HUMAN | [view interactions] | Computational | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DOCK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SNX18_HUMAN | [view interactions] | Computational | no | no |
| NPHN_HUMAN | [view interactions] | Computational | no | no |
| EFNB1_HUMAN | [view interactions] | Computational | no | yes |