ABI1_HUMAN
Evidence for PS localization
Functions
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000206 | LIG_SH3_PxxDY_5 | LIG | 417 | 421 | - |
| ELMI000206 | LIG_SH3_PxxDY_5 | LIG | 417 | 421 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABI1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 31.7460 | 4 | no |
| GO:0000166 | nucleotide binding | 27.7778 | 4 | no |
| GO:0017076 | purine nucleotide binding | 27.7778 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 27.7778 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.7778 | 4 | no |
| GO:0005524 | ATP binding | 21.4286 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 21.4286 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.4286 | 5 | no |
| GO:0045296 | cadherin binding | 16.6667 | 4 | yes |
| GO:0017124 | SH3 domain binding | 13.4921 | 4 | yes |
| GO:0019887 | protein kinase regulator activity | 5.5556 | 4 | yes |
| GO:0019209 | kinase activator activity | 2.3810 | 4 | yes |
| GO:0030295 | protein kinase activator activity | 2.3810 | 5 | yes |
| GO:0030296 | protein tyrosine kinase activator activity | 1.5873 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABI1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 69.8413 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 58.7302 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.7619 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 52.3810 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 49.2063 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 47.6190 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 46.8254 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.8571 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 40.4762 | 4 | no |
| GO:0022607 | cellular component assembly | 40.4762 | 4 | no |
| GO:0006996 | organelle organization | 39.6825 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 38.8889 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.8889 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 38.8889 | 5 | no |
| GO:0030030 | cell projection organization | 38.0952 | 4 | yes |
| GO:0010468 | regulation of gene expression | 37.3016 | 6 | no |
| GO:0009893 | positive regulation of metabolic process | 37.3016 | 4 | yes |
| GO:0051049 | regulation of transport | 35.7143 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 34.9206 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 34.1270 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 34.1270 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 34.1270 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.1270 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 33.3333 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 33.3333 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 32.5397 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 31.7460 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 30.9524 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 30.1587 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 30.1587 | 5 | no |
| GO:0008104 | protein localization | 30.1587 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 30.1587 | 5 | no |
| GO:2000145 | regulation of cell motility | 26.9841 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 26.1905 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.1905 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 26.1905 | 4 | no |
| GO:0030334 | regulation of cell migration | 26.1905 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 26.1905 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.1905 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 26.1905 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 26.1905 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 25.3968 | 5 | no |
| GO:0048585 | negative regulation of response to stimulus | 25.3968 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 24.6032 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.6032 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 23.8095 | 4 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 23.8095 | 4 | yes |
| GO:0007169 | cell surface receptor protein tyrosine kinase signaling pathway | 23.8095 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 23.8095 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 23.8095 | 7 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 23.8095 | 6 | no |
| GO:0141124 | intracellular signaling cassette | 23.8095 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 23.8095 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 23.0159 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.0159 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.0159 | 6 | no |
| GO:0042981 | regulation of apoptotic process | 23.0159 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 23.0159 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 23.0159 | 4 | no |
| GO:0071310 | cellular response to organic substance | 23.0159 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 22.2222 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.2222 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.2222 | 4 | no |
| GO:0060341 | regulation of cellular localization | 22.2222 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.2222 | 7 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 22.2222 | 6 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 21.4286 | 5 | no |
| GO:0032880 | regulation of protein localization | 21.4286 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 21.4286 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 21.4286 | 5 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 21.4286 | 5 | no |
| GO:0043412 | macromolecule modification | 20.6349 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.6349 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 20.6349 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.6349 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.6349 | 5 | no |
| GO:0007015 | actin filament organization | 20.6349 | 5 | yes |
| GO:0010975 | regulation of neuron projection development | 20.6349 | 7 | no |
| GO:0036211 | protein modification process | 20.6349 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 18.2540 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 18.2540 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 18.2540 | 7 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 18.2540 | 4 | yes |
| GO:0031401 | positive regulation of protein modification process | 17.4603 | 7 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 16.6667 | 8 | yes |
| GO:0048812 | neuron projection morphogenesis | 16.6667 | 5 | yes |
| GO:0043085 | positive regulation of catalytic activity | 13.4921 | 4 | yes |
| GO:0043549 | regulation of kinase activity | 11.9048 | 5 | yes |
| GO:0045859 | regulation of protein kinase activity | 11.9048 | 6 | yes |
| GO:0051338 | regulation of transferase activity | 11.9048 | 4 | yes |
| GO:0008154 | actin polymerization or depolymerization | 10.3175 | 6 | yes |
| GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 7.9365 | 8 | yes |
| GO:0097581 | lamellipodium organization | 7.9365 | 6 | yes |
| GO:0033674 | positive regulation of kinase activity | 7.1429 | 6 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 7.1429 | 7 | yes |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 7.1429 | 9 | yes |
| GO:0051347 | positive regulation of transferase activity | 7.1429 | 5 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 6.3492 | 5 | yes |
| GO:0030097 | hemopoiesis | 6.3492 | 4 | yes |
| GO:0061515 | myeloid cell development | 4.7619 | 5 | yes |
| GO:0048813 | dendrite morphogenesis | 3.9683 | 6 | yes |
| GO:0035855 | megakaryocyte development | 3.1746 | 6 | yes |
| GO:0061097 | regulation of protein tyrosine kinase activity | 3.1746 | 7 | yes |
| GO:0061098 | positive regulation of protein tyrosine kinase activity | 3.1746 | 8 | yes |
| GO:0072673 | lamellipodium morphogenesis | 3.1746 | 5 | yes |
| GO:0009952 | anterior/posterior pattern specification | 2.3810 | 4 | yes |
| GO:0035282 | segmentation | 1.5873 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
| DIAP3_HUMAN | [view interactions] | Low throughput | no | no |
| BSN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAX_HUMAN | [view interactions] | Low throughput | no | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| NCK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ES8L1_HUMAN | [view interactions] | Low throughput | no | no |
| ES8L2_HUMAN | [view interactions] | Low throughput | no | yes |
| ES8L3_HUMAN | [view interactions] | Low throughput | no | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTA1_HUMAN | [view interactions] | Low throughput | no | no |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCF1_HUMAN | [view interactions] | Low throughput | no | no |
| SOS2_HUMAN | [view interactions] | Low throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| S25A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRA2B_HUMAN | [view interactions] | High throughput | no | yes |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPRB_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPP2_HUMAN | [view interactions] | High throughput | no | yes |
| NHSL3_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP77_HUMAN | [view interactions] | High throughput | no | no |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEBU_HUMAN | [view interactions] | High throughput | no | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K0408_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOFA1_HUMAN | [view interactions] | High throughput | no | yes |
| MR1L1_HUMAN | [view interactions] | High throughput | no | no |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRK_HUMAN | [view interactions] | High throughput | no | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FER_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS7_HUMAN | [view interactions] | High throughput | no | yes |
| FES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITK_HUMAN | [view interactions] | High throughput | no | no |
| CBLC_HUMAN | [view interactions] | High throughput | no | yes |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBLB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHC2_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| KCNK3_HUMAN | [view interactions] | High throughput | no | no |
| NXN_HUMAN | [view interactions] | High throughput | no | no |
| CAD23_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| FXL19_HUMAN | [view interactions] | High throughput | no | no |
| TTC23_HUMAN | [view interactions] | High throughput | no | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| RCOR3_HUMAN | [view interactions] | High throughput | no | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F124B_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CIP4_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYVM_HUMAN | [view interactions] | High throughput | no | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HHEX_HUMAN | [view interactions] | High throughput | no | no |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| RBM15_HUMAN | [view interactions] | High throughput | no | yes |
| NFASC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBTN1_HUMAN | [view interactions] | High throughput | no | no |
| CV015_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| RYK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN511_HUMAN | [view interactions] | High throughput | no | yes |
| CMA1D_HUMAN | [view interactions] | High throughput | no | no |
| UBX11_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LHX4_HUMAN | [view interactions] | High throughput | no | no |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| AMZ1_HUMAN | [view interactions] | High throughput | no | no |
| WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| RHG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TLS1_HUMAN | [view interactions] | High throughput | no | yes |
| AIMP2_HUMAN | [view interactions] | High throughput | no | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PRRT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCRG1_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD123_HUMAN | [view interactions] | High throughput | no | yes |
| NCKPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIPF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| PPIH_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| PSA3_HUMAN | [view interactions] | High throughput | no | no |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
| PRP16_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| BRSK2_HUMAN | [view interactions] | High throughput | no | no |
| LRC4C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA4_HUMAN | [view interactions] | High throughput | no | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PR40A_HUMAN | [view interactions] | High throughput | no | no |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM3_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| YLPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PREX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| CAC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| NHS_HUMAN | [view interactions] | High throughput | no | yes |
| THOC6_HUMAN | [view interactions] | High throughput | no | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| PDCD4_HUMAN | [view interactions] | High throughput | no | yes |
| KPRA_HUMAN | [view interactions] | High throughput | no | no |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |