ABI1_HUMAN
Evidence for PS localization
Functions
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000206 | LIG_SH3_5 | LIG | 417 | 421 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABI1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 32.2034 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 31.3559 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 31.3559 | 4 | no |
| GO:0003779 | actin binding | 24.5763 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.7288 | 5 | no |
| GO:0005524 | ATP binding | 22.8814 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 22.8814 | 5 | no |
| GO:0045296 | cadherin binding | 15.2542 | 4 | yes |
| GO:0017124 | SH3 domain binding | 11.8644 | 4 | yes |
| GO:0019887 | protein kinase regulator activity | 5.9322 | 4 | yes |
| GO:0019209 | kinase activator activity | 3.3898 | 4 | yes |
| GO:0030295 | protein kinase activator activity | 3.3898 | 5 | yes |
| GO:0030296 | protein tyrosine kinase activator activity | 1.6949 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABI1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 72.0339 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 56.7797 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.5424 | 4 | no |
| GO:0009966 | regulation of signal transduction | 49.1525 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 46.6102 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 45.7627 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.7627 | 4 | no |
| GO:0022607 | cellular component assembly | 43.2203 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 42.3729 | 4 | no |
| GO:0006996 | organelle organization | 41.5254 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.6780 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 40.6780 | 4 | no |
| GO:0030030 | cell projection organization | 38.9831 | 4 | yes |
| GO:0051049 | regulation of transport | 38.9831 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 38.9831 | 5 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 38.9831 | 4 | no |
| GO:0033043 | regulation of organelle organization | 38.1356 | 5 | no |
| GO:0010468 | regulation of gene expression | 36.4407 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 34.7458 | 5 | no |
| GO:0023056 | positive regulation of signaling | 34.7458 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 34.7458 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 34.7458 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.7458 | 5 | no |
| GO:0071310 | cellular response to organic substance | 34.7458 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.8983 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 33.8983 | 6 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 33.0508 | 5 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 32.2034 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 32.2034 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 32.2034 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 31.3559 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 30.5085 | 5 | no |
| GO:0007010 | cytoskeleton organization | 29.6610 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 29.6610 | 5 | no |
| GO:0008104 | protein localization | 29.6610 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.8136 | 5 | no |
| GO:0097435 | supramolecular fiber organization | 27.9661 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 27.9661 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 27.9661 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 27.9661 | 5 | no |
| GO:0030155 | regulation of cell adhesion | 27.1186 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 27.1186 | 5 | no |
| GO:2000145 | regulation of cell motility | 27.1186 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 27.1186 | 4 | no |
| GO:0007015 | actin filament organization | 27.1186 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 26.2712 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.2712 | 4 | no |
| GO:0010638 | positive regulation of organelle organization | 25.4237 | 6 | no |
| GO:0030334 | regulation of cell migration | 25.4237 | 5 | no |
| GO:0031399 | regulation of protein modification process | 25.4237 | 6 | no |
| GO:0110053 | regulation of actin filament organization | 25.4237 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.4237 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 25.4237 | 4 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 25.4237 | 4 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 24.5763 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 24.5763 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 24.5763 | 5 | yes |
| GO:0042127 | regulation of cell population proliferation | 23.7288 | 4 | yes |
| GO:0010941 | regulation of cell death | 23.7288 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.7288 | 7 | no |
| GO:0036211 | protein modification process | 22.8814 | 4 | yes |
| GO:0043412 | macromolecule modification | 22.8814 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 22.8814 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 22.8814 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.8814 | 5 | no |
| GO:0080134 | regulation of response to stress | 22.8814 | 4 | no |
| GO:0031346 | positive regulation of cell projection organization | 22.8814 | 6 | no |
| GO:0009892 | negative regulation of metabolic process | 22.0339 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.0339 | 5 | no |
| GO:0051050 | positive regulation of transport | 22.0339 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.0339 | 4 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 22.0339 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.1864 | 4 | no |
| GO:0051495 | positive regulation of cytoskeleton organization | 21.1864 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.1864 | 6 | no |
| GO:0060341 | regulation of cellular localization | 21.1864 | 4 | no |
| GO:0002684 | positive regulation of immune system process | 20.3390 | 4 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.3390 | 6 | no |
| GO:0030335 | positive regulation of cell migration | 20.3390 | 6 | no |
| GO:0040017 | positive regulation of locomotion | 20.3390 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 20.3390 | 8 | no |
| GO:0043067 | regulation of programmed cell death | 20.3390 | 5 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.3390 | 7 | no |
| GO:2000147 | positive regulation of cell motility | 20.3390 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 20.3390 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 20.3390 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 20.3390 | 4 | no |
| GO:0022604 | regulation of cell morphogenesis | 20.3390 | 5 | no |
| GO:0032990 | cell part morphogenesis | 18.6441 | 4 | yes |
| GO:0048858 | cell projection morphogenesis | 18.6441 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 17.7966 | 6 | yes |
| GO:0016310 | phosphorylation | 17.7966 | 5 | yes |
| GO:0048812 | neuron projection morphogenesis | 16.1017 | 7 | yes |
| GO:0006468 | protein phosphorylation | 16.1017 | 5 | yes |
| GO:0018193 | peptidyl-amino acid modification | 15.2542 | 5 | yes |
| GO:0008154 | actin polymerization or depolymerization | 12.7119 | 6 | yes |
| GO:0018212 | peptidyl-tyrosine modification | 11.0169 | 6 | yes |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 11.0169 | 6 | yes |
| GO:0097581 | lamellipodium organization | 9.3220 | 6 | yes |
| GO:0008285 | negative regulation of cell population proliferation | 5.9322 | 5 | yes |
| GO:0048813 | dendrite morphogenesis | 5.0847 | 8 | yes |
| GO:0061515 | myeloid cell development | 5.0847 | 4 | yes |
| GO:0098751 | bone cell development | 4.2373 | 4 | yes |
| GO:0035855 | megakaryocyte development | 3.3898 | 5 | yes |
| GO:0072673 | lamellipodium morphogenesis | 3.3898 | 7 | yes |
| GO:0009952 | anterior/posterior pattern specification | 2.5424 | 4 | yes |
| GO:0035282 | segmentation | 1.6949 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ABI1_HUMAN |
|---|---|---|---|---|
| DOID:0060038 | specific developmental disorder | 1.6949 | 3 | no |
| DOID:1059 | intellectual disability | 1.6949 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 1.6949 | 6 | no |
| DOID:440 | neuromuscular disease | 1.6949 | 5 | no |
| DOID:574 | peripheral nervous system disease | 1.6949 | 3 | no |
| DOID:870 | neuropathy | 1.6949 | 4 | no |
| DOID:0111962 | combined immunodeficiency | 1.6949 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.6949 | 3 | no |
| DOID:0050700 | cardiomyopathy | 1.6949 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.6949 | 5 | no |
| DOID:114 | heart disease | 1.6949 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 1.6949 | 6 | no |
| DOID:1289 | neurodegenerative disease | 1.6949 | 4 | no |
| DOID:331 | central nervous system disease | 1.6949 | 3 | no |
| DOID:0050686 | organ system cancer | 1.6949 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ES8L1_HUMAN | [view interactions] | Low throughput | no | no |
| ES8L2_HUMAN | [view interactions] | Low throughput | no | yes |
| ES8L3_HUMAN | [view interactions] | Low throughput | no | no |
| CBL_HUMAN | [view interactions] | Low throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SYNJ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SPTA1_HUMAN | [view interactions] | Low throughput | no | no |
| ABL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCF1_HUMAN | [view interactions] | Low throughput | no | no |
| SOS2_HUMAN | [view interactions] | Low throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| BAIP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SOS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EPS8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
| DIAP3_HUMAN | [view interactions] | Low throughput | no | no |
| BSN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAX_HUMAN | [view interactions] | Low throughput | no | yes |
| MYC_HUMAN | [view interactions] | Low throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| RCOR3_HUMAN | [view interactions] | High throughput | no | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F124B_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| CIP4_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view interactions] | High throughput | no | yes |
| SYVM_HUMAN | [view interactions] | High throughput | no | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HHEX_HUMAN | [view interactions] | High throughput | no | no |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| RBM15_HUMAN | [view interactions] | High throughput | no | yes |
| NFASC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBTN1_HUMAN | [view interactions] | High throughput | no | no |
| CV015_HUMAN | [view interactions] | High throughput | no | no |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| CCHCR_HUMAN | [view interactions] | High throughput | no | no |
| RYK_HUMAN | [view interactions] | High throughput | no | no |
| ZN511_HUMAN | [view interactions] | High throughput | no | yes |
| OD3L2_HUMAN | [view interactions] | High throughput | no | no |
| UBX11_HUMAN | [view interactions] | High throughput | no | yes |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LHX4_HUMAN | [view interactions] | High throughput | no | no |
| PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| T2EB_HUMAN | [view interactions] | High throughput | no | yes |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| IKIP_HUMAN | [view interactions] | High throughput | no | no |
| AMZ1_HUMAN | [view interactions] | High throughput | no | no |
| WASF3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COG6_HUMAN | [view interactions] | High throughput | no | yes |
| CCD22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAAT_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| RHG12_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
| CCR1_HUMAN | [view interactions] | High throughput | no | no |
| THIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTCS_HUMAN | [view interactions] | High throughput | no | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCRG1_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD123_HUMAN | [view interactions] | High throughput | no | yes |
| NCKPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| WASL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WIPF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI14_HUMAN | [view interactions] | High throughput | no | yes |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMY11_HUMAN | [view interactions] | High throughput | no | no |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PR40A_HUMAN | [view interactions] | High throughput | no | yes |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM3_HUMAN | [view interactions] | High throughput | no | no |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| YLPM1_HUMAN | [view interactions] | High throughput | no | yes |
| PREX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| CAC1A_HUMAN | [view interactions] | High throughput | no | no |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAPH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THOC6_HUMAN | [view interactions] | High throughput | no | yes |
| NHS_HUMAN | [view interactions] | High throughput | no | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NHSL1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPRB_HUMAN | [view interactions] | High throughput | no | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB5_HUMAN | [view interactions] | High throughput | no | yes |
| PRPS2_HUMAN | [view interactions] | High throughput | no | no |
| KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRA2B_HUMAN | [view interactions] | High throughput | no | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPRA_HUMAN | [view interactions] | High throughput | no | no |
| PDCD4_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP76_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP77_HUMAN | [view interactions] | High throughput | no | no |
| ITA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K1522_HUMAN | [view interactions] | High throughput | no | yes |
| DPP2_HUMAN | [view interactions] | High throughput | no | yes |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| GAS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| NEBU_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK6_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| K0408_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE2_HUMAN | [view interactions] | High throughput | no | no |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MR1L1_HUMAN | [view interactions] | High throughput | no | no |
| MOFA1_HUMAN | [view interactions] | High throughput | no | yes |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRK_HUMAN | [view interactions] | High throughput | no | no |
| FGR_HUMAN | [view interactions] | High throughput | no | no |
| YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FER_HUMAN | [view interactions] | High throughput | no | yes |
| SOCS7_HUMAN | [view interactions] | High throughput | no | yes |
| FES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASA1_HUMAN | [view interactions] | High throughput | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P55G_HUMAN | [view interactions] | High throughput | no | yes |
| ABL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITK_HUMAN | [view interactions] | High throughput | no | no |
| CBLC_HUMAN | [view interactions] | High throughput | no | yes |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBLB_HUMAN | [view interactions] | High throughput | no | yes |
| SHC2_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXN_HUMAN | [view interactions] | High throughput | no | no |
| CAD23_HUMAN | [view interactions] | High throughput | no | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| FXL19_HUMAN | [view interactions] | High throughput | no | no |
| TTC23_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| US6NL_HUMAN | [view interactions] | Computational | no | yes |
| VCAM1_HUMAN | [view interactions] | Computational | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PI3R6_HUMAN | [view interactions] | Computational | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARPC4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| WASP_HUMAN | [view interactions] | Computational | no | yes |
| PK3CB_HUMAN | [view interactions] | Computational | no | yes |
| ARPC5_HUMAN | [view interactions] | Computational | no | yes |
| ARP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ITA4_HUMAN | [view interactions] | Computational | no | no |
| ARF1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARPC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ARC1B_HUMAN | [view interactions] | Computational | no | no |
| ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| FNBP1_HUMAN | [view interactions] | Computational | no | yes |
| EGF_HUMAN | [view interactions] | Computational | no | no |
| SRA1_HUMAN | [view interactions] | Computational | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PK3CG_HUMAN | [view interactions] | Computational | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | Computational | yes | yes |